TWAS hub - SCFD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.1040	0.0370	9.8e-04	0.027	NA	0.032	NA	0.026	3.6e-03	NA	1.9e-03	NA	4.6e-03
2	METSIM	Adipose	0.0629	0.0235	1.2e-04	0.056	0.039	0.039	0.052	0.053	7.5e-09	1.3e-06	1.3e-06	2.8e-08	1.9e-08
3	YFS	Blood	0.0118	0.0064	1.9e-02	-0.001	0.001	0.000	0.002	0.001	8.1e-01	1.4e-01	4.9e-01	7.7e-02	1.8e-01
4	TCGA	Breast Invasive Carcinoma	0.0426	0.0159	1.7e-05	0.029	0.019	0.032	NA	0.031	8.7e-07	7.7e-05	3.1e-07	NA	4.8e-07
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.0729	0.0287	1.9e-04	0.059	0.027	0.024	NA	0.045	3.3e-07	4.6e-04	9.7e-04	NA	7.0e-06
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1640	0.0650	1.3e-03	-0.001	0.032	0.018	NA	0.002	3.8e-01	5.9e-03	3.2e-02	NA	2.5e-01
7	TCGA	Brain Lower Grade Glioma	0.0535	0.0305	9.0e-03	0.022	0.007	0.025	NA	0.012	1.3e-03	4.6e-02	6.2e-04	NA	1.3e-02
8	TCGA	Lung Adenocarcinoma	0.0608	0.0247	7.2e-04	0.023	0.024	0.011	NA	0.015	9.5e-04	6.4e-04	1.7e-02	NA	6.5e-03
9	TCGA	Ovarian Serous Cystadenocarcinoma	0.0740	0.0340	3.5e-03	0.018	0.023	0.012	NA	0.016	2.1e-02	9.8e-03	4.5e-02	NA	2.9e-02
10	TCGA	Pheochromocytoma and Paraganglioma	0.1150	0.0560	7.9e-03	0.035	0.062	0.024	NA	0.020	1.5e-02	1.8e-03	3.8e-02	NA	5.1e-02
11	TCGA	Thyroid Carcinoma	0.1200	0.0400	3.1e-07	0.033	0.065	0.047	NA	0.060	3.4e-04	6.5e-07	2.0e-05	NA	1.6e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Fractured/broken bones in last 5 years	8.7	11.2	17.3	3.0	3.3	1.5	3.7	4.2	2.7	3.4	3.6	3.8	3.3	3.7
Hair/balding pattern: Pattern 4	6.3	15.2	38.0	2.5	3.9	3.0	4.5	6.2	0.9	4.6	3.1	3.7	2.9	4.9
Prostate Cancer	4.4	6.1	13.7	1.8	1.0	1.7	2.9	3.7	1.8	1.7	2.1	3.0	2.8	3.3
Tinnitus: Yes, now most or all of the time	4.2	4.9	9.4	1.4	2.5	1.3	2.6	3.1	2.3	2.7	0.3	2.7	2.4	1.3
Eye problems/disorders: None of the above	4.0	4.7	10.2	1.9	2.5	1.8	2.4	3.2	0.1	2.5	1.3	2.0	2.0	2.5
Shortness of breath walking on level ground	3.7	4.4	10.6	1.7	2.1	3.1	1.1	1.5	3.3	2.5	1.9	2.2	1.5	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	3.6	3.8	8.8	1.5	2.4	3.0	2.0	1.2	1.6	2.1	1.8	1.8	1.6	1.8
Coronary Artery Disease (CAD)	3.2	3.9	7.2	-1.9	-2.7	-1.1	-1.7	-1.4	-2.7	-2.1	-2.6	-1.6	-1.7	-1.4
Hair/balding pattern: Pattern 3	3.0	4.4	8.0	-1.2	-2.6	-2.3	-2.4	-2.4	-1.0	-2.8	-1.5	-1.8	-2.5	-1.6
Fed-up feelings	2.9	5.3	8.8	1.3	2.1	3.0	1.9	2.9	1.5	2.4	2.5	1.9	2.6	2.7
Eye problems/disorders: Cataract	2.9	3.3	7.0	-1.5	-2.2	-1.3	-1.7	-2.6	-0.3	-2.6	-0.9	-1.8	-1.9	-1.8
Ever used hormone-replacement therapy (HRT)	2.7	3.5	8.3	2.9	1.8	-0.9	2.0	2.1	-1.5	1.7	1.3	2.1	0.5	2.4
Number of operations (self-reported)	2.4	3.6	8.4	2.6	2.9	1.5	1.9	1.6	1.9	2.3	1.8	1.1	1.0	1.4
Bipolar Disorder (2011)	2.3	2.2	6.4	-1.3	-1.5	-1.2	-1.4	-1.1	-0.5	-0.9	-0.9	-2.0	-1.9	-2.5
Medication: Ramipril	2.2	2.9	7.5	-1.3	-1.4	-0.3	-1.6	-1.9	-1.5	-1.5	-1.4	-2.1	-2.7	-1.8
Supplements: Glucosamine	2.1	2.7	8.5	2.9	2.4	0.3	2.1	1.6	0.6	0.6	0.5	1.5	1.2	2.1
Lupus	2.0	3.0	6.6	-0.4	-1.7	-1.5	-2.0	-1.5	-0.4	-1.7	-1.0	-2.3	-2.6	-2.3
Neuroticism	2.0	4.8	12.3	0.6	1.5	3.3	2.0	3.5	0.7	1.9	2.8	1.6	1.8	2.3
Qualifications: None of the above	2.0	4.3	6.9	1.8	2.2	2.0	1.9	1.8	2.4	0.9	2.3	2.0	2.4	2.6
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.2	9.8	1.5	1.8	3.1	1.2	1.7	2.3	1.5	1.7	1.4	1.0	1.7
Medication: Ventolin 100micrograms inhaler	2.0	2.6	9.3	0.3	0.8	3.0	1.0	-0.1	0.4	1.1	0.5	2.2	3.1	1.3
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	4.2	-0.5	-1.1	-1.6	-1.9	-2.0	0.7	-1.1	0.6	-0.9	-2.0	-2.0
Heart disease (mother)	1.9	2.3	6.0	1.5	2.0	1.3	2.5	0.6	1.7	0.7	0.5	1.8	1.9	1.1
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	5.2	0.5	0.2	1.6	1.3	2.2	0.5	0.8	2.3	1.4	1.2	2.2
Pain experienced in last month	1.8	3.0	8.4	-0.6	-1.2	-2.9	-1.4	-1.9	-1.2	-1.3	-2.3	-1.8	-1.4	-1.8
Alcohol drinker status: Previous	1.8	2.1	5.2	0.7	0.9	1.9	1.7	2.1	-0.3	1.2	0.5	1.5	1.1	2.3
Age at First Birth	1.7	2.5	6.5	-1.0	-1.1	-1.6	-2.4	-0.9	-2.1	-0.1	-2.5	-1.0	-0.7	-2.0
Triglycerides	1.7	2.8	6.1	2.3	2.5	1.4	1.6	1.4	-0.2	1.7	1.4	1.4	1.7	1.9
Leg fat-free mass (left)	1.7	8.8	29.6	-1.9	-3.0	-2.0	-3.5	-5.4	-0.1	-3.1	-2.7	-1.5	-2.2	-3.9
Sitting height	1.7	11.8	25.3	-2.0	-1.8	-3.2	-3.7	-4.9	-2.6	-3.0	-5.0	-3.2	-2.2	-4.2
Leg predicted mass (left)	1.7	8.8	28.9	-1.9	-3.0	-2.0	-3.5	-5.4	-0.1	-3.0	-2.6	-1.4	-2.3	-3.9
Neck or shoulder pain in last month	1.7	2.4	6.2	1.1	1.5	2.5	1.3	0.8	0.3	0.7	1.7	1.1	1.7	2.5
Leg fat-free mass (right)	1.7	9.0	29.2	-2.0	-3.3	-1.9	-3.7	-5.4	-0.1	-3.2	-2.5	-1.5	-2.3	-3.8
Leg predicted mass (right)	1.7	9.0	28.9	-1.9	-3.2	-1.9	-3.6	-5.4	0.0	-3.2	-2.5	-1.5	-2.3	-3.8
Heart disease (siblings)	1.7	2.1	7.3	-0.9	-2.7	0.5	-0.7	-2.3	-0.2	-2.6	-0.2	1.0	0.3	-0.4
Hip circumference	1.6	6.8	17.5	-1.6	-3.2	-1.5	-3.1	-4.2	-0.9	-2.8	-1.5	-2.3	-2.5	-2.9
Hearing aid user	1.6	1.8	3.8	0.6	1.9	1.1	1.8	1.7	-0.0	1.8	-0.1	1.6	1.4	0.6
Basal metabolic rate	1.6	8.8	29.3	-1.6	-3.2	-2.3	-3.7	-5.4	-0.6	-3.0	-2.7	-1.3	-2.1	-3.7
Bipolar Disorder (2018)	1.5	2.4	4.1	-0.9	-1.3	-1.9	-1.6	-1.8	-1.9	-1.2	-1.2	-2.0	-1.3	-1.8
Mean Putamen Volume	1.5	1.8	3.4	-1.3	-1.4	-0.2	-1.7	-0.9	-1.7	-1.8	-1.3	-1.5	-0.4	-1.3
Medication: Atenolol	1.5	1.9	5.1	0.2	0.1	1.4	1.4	1.9	0.3	0.4	2.1	1.5	0.9	2.2
Neuroticism score	1.5	3.1	8.2	0.7	0.8	2.9	1.3	2.7	0.7	1.3	2.5	1.3	1.3	1.9
Weight	1.5	7.1	21.7	-1.7	-3.1	-2.2	-3.4	-4.7	-0.6	-2.8	-2.3	-1.6	-2.0	-2.9
Worrier / anxious feelings	1.5	2.9	7.4	0.6	0.7	2.7	1.4	2.3	0.1	1.1	1.4	1.7	2.0	2.4
Illnesses of mother	1.5	1.8	5.2	-0.9	-0.5	-2.3	-1.4	-0.9	-1.3	0.1	-1.4	-1.4	-1.3	-1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	1.9	3.3	-1.3	-1.1	-0.7	-1.1	-1.8	-1.3	-1.3	-1.7	-1.7	-1.4	-1.6
Wheeze or whistling in the chest in last year	1.5	2.6	6.7	1.0	1.1	2.6	0.9	0.7	2.0	1.5	1.3	1.9	2.1	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	5.0	0.3	0.1	-2.2	-0.2	-1.5	-1.2	-1.0	-1.8	-1.5	-1.6	-1.2
Medication: Omeprazole	1.5	1.8	5.2	0.4	0.1	1.2	1.4	1.7	0.2	0.6	2.3	1.3	1.1	2.2
Age at last live birth	1.5	2.2	4.0	1.1	1.3	0.7	2.0	1.4	1.5	2.0	1.3	1.7	1.7	1.0
Cholesterol lowering medication	1.5	2.2	3.8	-1.7	-1.9	-1.9	-1.6	-1.2	-1.0	-1.3	-0.0	-0.9	-1.7	-1.7
Supplements: Calcium	1.5	1.6	4.1	1.0	1.3	0.4	2.0	1.5	0.4	1.4	1.6	1.0	0.3	1.8
HbA1C	1.4	1.5	4.0	-0.3	1.2	2.0	1.4	1.3	0.0	0.8	1.4	0.8	1.3	1.6
High blood pressure (mother)	1.4	2.0	4.5	1.6	0.4	1.8	0.8	2.1	1.0	0.5	2.1	1.7	0.5	1.5
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	6.0	1.4	1.1	1.9	1.3	0.9	2.5	1.0	1.8	1.8	0.8	1.2
Whole body fat-free mass	1.4	8.2	29.2	-1.3	-3.0	-2.2	-3.5	-5.4	-0.5	-2.9	-2.7	-0.9	-1.8	-3.7
Whole body water mass	1.4	8.0	28.5	-1.3	-3.0	-2.3	-3.5	-5.3	-0.3	-2.9	-2.6	-0.8	-1.8	-3.6
Ulcerative Colitis	1.3	1.9	6.6	-2.6	-1.0	-1.5	-0.8	0.0	-0.9	0.9	-0.1	-1.1	-2.1	-1.7
Lung FEV1/FVC ratio	1.3	6.8	15.1	-3.9	-3.5	-1.5	-3.0	-2.8	0.3	-2.2	-1.3	-1.5	-2.8	-3.4
Sensitivity / hurt feelings	1.3	2.3	5.2	1.5	1.4	1.7	2.0	2.3	0.3	0.1	0.8	0.9	2.0	1.8
Medication: Co-codamol	1.3	1.5	4.5	-1.7	-1.6	1.2	-0.6	-1.5	-0.9	-2.1	-0.0	-0.9	-0.5	0.2
Diabetes (mother)	1.3	1.6	8.1	-0.2	0.6	2.8	0.8	0.9	0.6	0.6	0.9	1.2	1.2	1.8
Average weekly fortified wine intake	1.3	1.5	6.1	-0.4	0.0	2.0	0.5	1.5	2.5	0.7	1.2	0.9	0.9	0.8
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.7	-1.0	-0.1	-1.9	-0.9	-1.3	-1.6	-0.3	-1.4	-1.4	-0.8	-1.3
Trunk fat-free mass	1.3	7.2	26.0	-0.9	-2.8	-2.3	-3.3	-5.1	-0.6	-2.7	-2.8	-0.6	-1.5	-3.3
Trunk predicted mass	1.3	7.2	25.8	-1.0	-2.8	-2.3	-3.3	-5.1	-0.6	-2.7	-2.7	-0.6	-1.5	-3.3
Chronic bronchitis/emphysema (mother)	1.3	1.5	3.7	0.5	1.6	0.8	1.9	1.2	0.2	1.1	1.2	1.0	1.5	1.6
Had major operations	1.3	1.6	5.0	1.2	0.9	1.3	0.6	1.2	2.1	0.9	2.2	1.1	0.3	0.6
Commuting to job workplace: Car/motor vehicle	1.3	1.5	3.6	-1.3	-1.9	-1.0	-1.7	-0.7	-0.7	-1.3	-1.0	-1.2	-1.0	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.6	11.1	-1.0	-1.0	-0.7	-1.7	-2.2	0.0	-0.8	-3.3	-1.4	-0.3	-2.3
Type 2 Diabetes (T2D) (2018)	1.2	2.2	6.2	0.5	0.5	2.1	1.1	0.9	0.8	-0.1	2.5	2.0	1.8	1.9
Current tobacco smoking	1.2	2.0	8.5	-0.6	-0.4	-0.8	-1.4	-1.7	-1.0	-0.9	-2.9	-1.7	-0.9	-1.4
Relative age voice broke	1.2	1.8	5.9	2.4	1.9	-0.1	1.0	1.2	1.1	1.8	-0.1	1.0	1.6	-0.2
Whole body fat mass	1.2	4.9	12.1	-1.8	-2.7	-1.7	-2.8	-3.5	-0.8	-2.4	-1.7	-1.8	-2.0	-2.2
Arm predicted mass (right)	1.2	6.2	24.0	-0.9	-2.7	-2.6	-3.0	-4.9	-0.6	-2.5	-2.3	-0.3	-1.3	-2.7
Arm predicted mass (left)	1.2	6.1	22.1	-0.7	-2.8	-2.6	-3.1	-4.7	-0.8	-2.4	-2.1	-0.2	-1.4	-2.8
Schizophrenia vs Biploar Disorder	1.1	1.5	3.1	0.8	0.5	-0.1	1.7	1.8	1.7	1.1	1.6	1.3	0.3	0.9
Worry (Nagel 2018)	1.1	2.3	5.3	0.9	0.9	2.3	1.3	2.3	0.5	1.5	1.9	1.7	0.4	1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.6	6.9	-1.8	-0.2	-2.0	-0.6	0.1	-2.6	-0.2	-1.7	-2.3	-2.4	-0.7
Nervous feelings	1.1	2.1	4.5	1.2	1.2	2.1	1.3	1.7	1.3	1.6	1.5	1.9	0.5	0.8
Had menopause	1.1	1.3	3.8	1.5	0.9	-0.8	2.0	0.4	-0.9	0.6	0.8	1.1	0.6	1.9
Standing height	1.1	11.3	27.9	-1.6	-1.9	-3.7	-3.3	-4.9	-2.1	-2.9	-5.3	-3.3	-1.8	-3.8
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	4.2	-1.2	-0.9	-0.7	-0.9	-1.3	-0.2	-1.0	-1.2	-2.0	-1.8	-1.7
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	5.0	0.8	1.1	1.4	0.6	0.5	0.6	1.0	1.1	1.7	2.2	0.4
Arm fat-free mass (right)	1.1	5.4	22.1	-0.5	-2.4	-2.4	-2.7	-4.7	-0.6	-2.1	-2.1	-0.1	-1.3	-2.6
Comparative body size at age 10	1.1	3.1	5.3	-1.5	-2.1	-2.1	-1.9	-1.9	-2.3	-1.5	-1.0	-1.1	-1.9	-1.5
Mouth/teeth dental problems: Loose teeth	1.1	1.3	5.2	1.7	2.3	0.2	0.5	0.3	1.2	1.4	-0.1	0.7	1.1	-0.6
Leg pain on walking	1.1	1.4	3.5	1.5	0.5	1.9	0.7	-0.2	0.8	0.3	1.0	1.9	1.0	1.5
Arm fat-free mass (left)	1.1	5.8	20.3	-0.9	-2.7	-2.5	-3.0	-4.5	-0.6	-2.2	-2.1	-0.3	-1.4	-2.9
Neuroticism (Nagel 2018)	1.0	2.3	5.9	1.0	1.2	1.9	1.6	2.4	0.7	1.2	1.7	1.3	1.3	1.6
Primary Biliary Cirrhosis	1.0	1.4	4.1	0.5	1.1	1.8	2.0	1.5	0.6	0.9	1.2	0.7	0.3	1.2
BMI	1.0	5.7	15.8	-2.0	-4.0	0.3	-3.5	-4.0	0.7	-3.2	-0.2	-0.3	-0.9	-1.9
Taking other prescription medications	1.0	1.6	5.1	0.5	0.5	0.5	1.3	0.4	0.9	0.6	1.8	2.3	1.9	1.2
Trunk fat mass	1.0	4.2	10.6	-1.7	-2.4	-1.4	-2.6	-3.2	-0.4	-2.2	-1.6	-1.8	-1.9	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	8.1	-1.2	0.7	-1.9	-0.1	0.5	-2.8	0.4	-1.4	-2.1	-1.9	-0.3
Happiness	1.0	1.3	3.3	1.1	0.9	-0.3	1.0	1.2	1.6	1.3	1.8	1.3	0.6	0.3
Worry too long after embarrassment	1.0	1.6	6.9	0.1	0.6	2.6	1.3	1.8	-1.1	0.6	0.9	0.9	0.9	1.4
Medication for pain relief, constipation, heartburn	1.0	1.6	5.3	0.2	-0.1	-2.3	-1.9	-0.8	0.1	-0.4	-1.6	-1.2	-0.7	-1.9
Migraine (self-reported)	1.0	1.2	3.6	1.9	-0.0	-1.4	1.2	1.1	0.7	-0.3	1.1	0.8	-0.4	1.5
Commuting to job workplace: Walk	1.0	1.0	3.9	-0.2	-1.0	0.0	-1.2	-2.0	0.2	-1.5	0.4	-0.3	-0.6	-1.5
Medication: Gliclazide	1.0	1.1	4.4	0.4	0.6	1.0	0.8	-1.0	0.7	0.4	2.1	1.7	1.0	0.8
Smoking status: Current	1.0	1.5	6.7	-0.7	-0.2	-0.3	-1.4	-1.4	-0.6	-0.7	-2.6	-1.5	-0.9	-1.3
Number of self-reported non-cancer illnesses	1.0	1.7	5.7	-2.2	-2.4	1.4	-0.9	-0.2	-0.3	-1.4	1.4	1.0	-0.0	0.9
Ovarian Cancer	0.9	1.2	3.3	1.3	0.8	0.8	1.7	0.8	1.4	-0.4	0.1	0.9	1.0	1.8
Age when periods started (menarche)	0.9	2.2	5.0	-1.2	-1.5	-1.5	-1.9	-0.9	0.9	-0.6	-0.5	-2.0	-2.2	-1.8
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.8	-1.8	-1.9	0.2	-1.4	-0.4	-1.1	-1.1	-1.2	-0.4	0.0	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	3.0	0.5	0.3	1.5	1.2	0.3	0.7	0.6	1.7	1.2	0.9	0.7
Depression (self-reported)	0.9	1.1	3.8	-1.0	-1.1	-0.4	-1.2	-0.6	1.0	-0.1	0.6	-0.6	-2.0	-1.4
Arm fat mass (right)	0.9	3.6	9.6	-1.4	-2.5	-1.1	-2.5	-3.1	0.0	-2.1	-1.0	-1.2	-2.0	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	3.9	-1.8	-1.5	-1.0	-1.1	-0.5	-0.7	-0.4	-0.2	-0.8	-2.0	-1.3
Ever highly irritable/argumentative for 2 days	0.9	1.1	4.2	0.9	1.0	0.4	1.1	0.9	2.0	1.2	1.2	0.1	0.8	-0.1
Medication: Seretide 50 evohaler	0.9	1.0	4.6	1.3	1.2	-2.1	-0.2	0.2	0.9	1.2	0.6	-0.2	-0.7	-0.8
Suffer from ‘nerves’	0.9	1.3	4.7	0.1	0.6	2.2	0.5	1.2	1.5	1.0	1.5	-0.1	-0.9	1.2
Chest pain or discomfort	0.9	1.3	3.3	1.1	0.8	1.8	1.6	0.6	1.6	0.9	1.1	0.6	0.0	1.2
Mood swings	0.9	1.6	2.9	0.8	0.9	1.5	1.2	1.7	1.3	1.5	1.7	0.9	0.4	1.2
Long-standing illness, disability or infirmity	0.9	1.4	4.8	0.8	-0.2	1.8	0.8	-0.7	-0.5	0.1	1.3	2.2	1.6	1.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.7	-1.2	-1.9	0.9	-1.4	-1.4	-1.2	-1.1	-0.3	0.1	-0.7	-0.6
Depression (Nagel 2018)	0.8	1.2	4.6	0.2	0.3	2.1	0.9	0.4	1.5	0.6	0.9	0.9	1.6	0.8
Breast Cancer	0.8	1.8	7.6	0.5	-1.8	-0.4	-1.0	-2.3	0.2	-2.8	1.0	-0.4	-0.2	0.8
Relative age of first facial hair	0.8	1.7	7.4	2.7	1.1	0.4	0.6	1.8	1.5	1.3	0.0	1.2	1.2	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	5.2	-0.1	0.4	1.9	0.5	0.5	2.3	0.3	0.9	0.2	1.1	0.0
Qualifications: CSEs or equivalent	0.8	1.1	2.3	-1.0	-0.8	0.4	-1.5	-1.0	0.5	-1.1	-0.8	-1.4	-0.8	-1.5
Diabetes (self-reported)	0.8	1.3	3.7	0.5	0.8	1.4	1.6	0.2	0.5	0.3	1.9	1.6	1.1	1.1
Exposure to tobacco smoke at home	0.8	0.9	2.3	1.3	1.1	0.7	0.4	0.8	1.5	0.8	1.4	0.4	-0.6	0.3
Blood clot in the leg (DVT)	0.8	1.0	3.0	-1.1	-1.7	1.0	-1.2	-1.2	-1.1	-0.9	-0.0	0.2	-0.6	-0.5
Number of children fathered	0.8	0.9	3.8	-0.1	0.5	0.1	0.4	0.3	1.9	0.1	0.8	1.1	2.0	0.3
Comparative height size at age 10	0.8	4.4	13.1	-0.4	-0.9	-1.9	-1.6	-2.9	-1.9	-2.2	-3.6	-1.8	-1.2	-2.6
Qualifications: nursing, teaching	0.8	1.3	3.5	-1.9	-1.2	0.1	-0.7	-0.8	-1.8	-1.1	-1.2	-1.3	-0.9	0.1
Arm fat mass (left)	0.8	3.4	8.6	-1.2	-2.4	-1.3	-2.4	-2.9	0.1	-2.0	-1.1	-1.2	-1.9	-1.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	5.6	0.3	1.3	2.4	0.5	0.2	0.9	0.9	0.9	0.3	0.5	0.6
Schizophrenia (2018)	0.7	1.4	7.3	-0.3	-0.0	1.0	1.0	1.7	0.8	0.6	2.7	1.3	0.5	0.8
Ulcerative Colitis (UC)	0.7	1.2	2.9	-1.7	-0.4	-1.3	-0.6	-0.7	-1.7	0.6	0.3	-0.8	-1.5	-1.4
Major Depression (MDD)	0.7	0.8	2.9	-1.7	-0.9	0.4	-0.1	0.8	1.0	-0.1	1.0	1.1	1.1	0.3
HDL Cholesterol	0.7	1.2	3.9	-0.8	-1.2	-1.0	-0.6	-1.1	0.3	-2.0	-1.8	-0.7	0.0	-0.6
Chronotype (morning person)	0.7	1.5	7.4	0.4	0.2	2.7	0.2	0.0	1.7	0.9	1.0	1.1	1.5	1.0
Medication: Metformin	0.7	1.0	2.7	-1.6	-0.9	1.5	-0.2	-0.9	0.1	-0.9	1.2	0.8	1.1	0.2
Severe depression (siblings)	0.7	0.8	2.8	0.0	0.0	-0.1	-0.9	-1.4	1.7	-0.1	-0.9	-0.7	-0.1	-1.5
Stomach or abdominal pain in last month	0.7	0.8	2.3	0.5	0.5	1.2	0.0	1.2	0.6	1.5	1.1	1.3	-0.1	0.2
Medication: Levothyroxine sodium	0.7	1.2	4.4	0.7	-0.6	-1.5	-1.2	0.1	2.1	-0.0	1.2	0.5	-0.8	-1.3
Financial difficulties in last 2 years	0.7	0.9	2.1	0.5	0.9	0.8	0.9	0.7	1.5	1.2	1.0	1.4	0.5	0.0
Pain all over the body in last month	0.7	0.8	2.4	-0.4	-0.9	0.7	-0.5	-1.1	-0.7	-0.9	-0.6	-0.4	-1.5	-1.2
Loud music exposure frequency	0.7	0.7	4.0	1.6	0.2	0.4	0.0	-0.5	2.0	-0.0	-0.0	1.0	-0.1	-0.2
Glaucoma (self-reported)	0.7	0.9	6.6	1.0	0.3	0.7	0.4	-0.3	2.6	-0.3	0.8	0.4	-0.1	0.3
Gout (self-reported)	0.7	1.0	2.5	-1.3	-1.6	1.6	-0.4	-0.2	0.8	-1.0	1.3	0.4	-0.3	-0.1
Leg fat mass (right)	0.7	2.8	8.9	-0.8	-2.0	-1.5	-2.1	-3.0	-0.7	-1.6	-1.1	-1.0	-1.7	-1.6
Number of full sisters	0.7	0.9	4.6	0.1	0.5	2.1	-0.1	-0.2	1.9	0.3	-0.7	-0.1	0.7	-0.5
Overall health rating	0.7	1.4	5.8	1.4	1.1	2.4	0.7	0.1	1.0	1.1	1.3	1.2	0.2	0.9
Supplements: Vitamin C	0.7	0.9	2.9	0.6	0.5	1.2	1.2	0.6	0.1	0.2	1.7	0.5	0.1	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	5.0	-0.6	-0.6	2.2	-0.1	0.7	-0.1	-0.2	1.0	0.5	-0.2	0.9
Osteoarthritis (self-reported)	0.7	0.9	2.9	0.8	0.8	1.7	0.5	0.9	0.1	1.0	1.2	1.1	-0.0	0.7
Mother’s age at death	0.7	0.8	4.1	-0.8	-0.8	0.1	-0.2	1.3	-2.0	0.4	0.0	0.5	-0.5	1.2
Financial situation satisfaction	0.7	0.8	1.9	1.3	-0.0	-1.3	-0.5	-1.3	0.1	0.9	-0.9	0.7	-0.0	-1.4
Medication: Lisinopril	0.7	0.9	1.7	0.5	-0.1	1.1	1.0	1.3	0.9	0.8	0.8	0.9	1.0	1.3
Illnesses of father: High blood pressure	0.7	0.9	2.2	-0.1	-1.4	-1.4	-0.8	-1.1	-0.2	-1.5	-0.7	-0.4	-0.7	-0.4
Pack years of smoking	0.7	1.0	3.5	1.0	1.9	-0.2	1.4	0.3	-0.1	1.0	-0.1	0.7	1.3	1.2
Leg fat mass (left)	0.7	2.6	8.5	-0.9	-2.2	-1.4	-2.1	-2.9	-0.8	-1.7	-0.9	-0.8	-1.5	-1.3
Alzheimer’s Disease (including proxy)	0.6	0.9	3.0	0.8	-1.0	-0.5	-1.1	-1.7	0.4	-0.7	-0.7	-0.4	-0.8	-1.3
Crohns Disease (2012)	0.6	1.0	3.3	-0.1	0.5	1.1	0.7	0.8	1.8	1.2	1.5	0.6	0.8	0.6
Heel T-Score	0.6	5.0	21.0	-1.0	1.0	-1.5	-0.7	1.9	-1.2	0.6	-2.0	-4.0	-4.6	-1.8
Height	0.6	12.3	27.9	-0.6	-2.8	-4.5	-3.4	-5.2	-2.0	-3.2	-5.3	-2.8	-1.5	-3.9
Lung FVC	0.6	2.9	10.5	2.7	0.9	1.1	1.2	0.9	-0.2	0.7	0.4	3.2	1.9	2.3
Number of treatments/medications taken	0.6	1.1	2.8	0.1	-0.3	0.8	1.4	-0.2	0.5	-0.8	1.2	1.6	1.1	1.7
Impedance of leg (right)	0.6	2.8	9.2	0.6	2.3	-0.1	1.9	3.0	-1.8	1.8	-0.4	-1.1	0.7	2.0
Hand grip strength (right)	0.6	1.6	6.0	-0.3	0.7	-2.1	-0.4	-1.5	-1.0	0.1	-2.5	-0.8	-0.3	-1.5
Chronic bronchitis/emphysema (father)	0.6	0.7	2.5	-0.7	-0.6	0.2	-1.2	-1.6	-1.2	-0.3	-0.8	0.2	0.3	-0.9
Body mass index (BMI)	0.6	2.4	7.5	-1.2	-2.6	-0.7	-2.1	-2.7	0.1	-1.7	-0.0	-0.2	-1.3	-1.3
Impedance of leg (left)	0.6	2.8	9.8	0.8	2.0	-0.0	1.8	3.1	-1.8	1.7	-0.0	-0.9	0.7	2.3
Number of incorrect matches in round	0.6	1.0	2.4	-0.9	-0.6	-1.2	-0.5	-1.2	-1.6	-0.6	-1.1	-1.5	-0.7	0.5
Had other major operations	0.6	0.7	2.6	0.8	1.6	-0.2	1.1	0.7	-0.3	1.4	-0.1	-0.4	-0.5	0.3
Length of working week for main job	0.6	0.7	3.7	1.0	0.7	0.1	0.4	0.1	1.9	1.3	0.2	0.1	0.5	-0.4
Angina (self-reported)	0.6	0.8	2.3	-1.1	-1.0	1.5	-0.0	-0.9	-0.1	-1.2	1.1	-0.1	-0.5	-0.3
Illnesses of siblings: Diabetes	0.6	0.7	2.9	-0.2	0.7	0.6	1.0	0.5	0.7	0.7	-0.2	0.8	1.7	0.9
Handedness (chirality/laterality): Left-handed	0.6	0.8	1.5	1.2	0.8	0.6	0.7	1.1	-0.9	1.1	1.1	0.8	0.8	-0.0
Back pain experienced in last month	0.6	0.9	3.4	-0.3	0.3	1.8	0.7	0.4	0.6	0.7	1.6	0.9	0.9	0.7
Mineral and other dietary supplements	0.6	0.8	2.9	-1.0	-1.2	1.3	-0.5	-0.7	0.8	-0.1	-0.4	-0.4	-0.1	-1.7
Breast cancer (self-reported)	0.6	0.7	2.7	0.1	0.0	-0.5	-0.6	0.1	-1.3	0.5	-1.6	-0.9	-0.8	-0.7
Guilty feelings	0.6	0.9	4.0	0.5	-0.1	2.0	0.9	0.9	-0.2	0.3	1.3	0.6	1.0	0.9
Supplements: Fish oil (including cod liver oil)	0.6	0.8	5.1	0.5	1.2	-2.2	0.1	0.1	-0.9	0.0	0.2	-0.2	-0.9	0.7
High cholesterol (Self-reported)	0.6	1.1	2.6	-0.9	-1.6	-0.8	-0.8	-0.6	-1.6	-1.6	0.9	0.7	-0.3	0.7
Medication: Bendroflumethiazide	0.6	0.9	2.8	0.4	-0.1	1.7	0.6	0.7	0.7	0.1	1.4	1.1	-0.2	1.4
Alcohol drinker status: Never	0.6	0.7	3.0	-0.8	-1.2	-1.0	-0.3	-0.5	0.4	-1.7	0.2	-0.9	0.1	-0.4
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.7	-0.3	0.8	0.8	1.2	0.6	-0.2	1.2	-0.2	0.7	1.3	0.7
Depressed Affect (Nagel 2018)	0.5	1.0	3.1	-0.1	0.0	1.4	0.8	1.8	0.9	0.5	1.5	0.4	0.9	1.2
Body Mass Index (BMI) (2010)	0.5	0.7	2.2	1.0	0.2	1.4	0.5	-0.1	1.1	0.5	1.5	0.6	0.5	0.8
LDL Cholesterol	0.5	0.8	2.2	-0.2	0.7	1.2	1.2	-0.1	-1.5	0.5	-0.4	0.8	0.8	1.0
Cardiovascular Disease	0.5	1.6	5.8	-0.7	-1.5	2.4	-0.2	0.9	-0.3	-0.8	1.3	1.2	-0.1	2.2
Systolic blood pressure, automated reading	0.5	1.5	3.0	0.9	1.3	-0.8	1.0	1.7	-1.3	1.3	-0.5	1.6	1.0	1.4
Angina	0.5	0.6	3.2	-0.6	-0.5	1.8	0.4	-0.5	0.0	-0.8	1.5	0.2	-0.3	0.1
Pack years adult smoking proportion	0.5	0.7	2.6	1.0	1.6	-0.4	1.0	0.2	-0.2	0.8	-0.5	0.4	1.1	0.8
Trunk fat percentage	0.5	2.0	3.5	-1.5	-1.7	-0.8	-1.7	-1.9	-0.3	-1.5	-0.7	-1.8	-1.7	-1.1
Waist circumference	0.5	2.0	7.6	-1.4	-2.0	-0.7	-1.8	-2.8	0.2	-1.4	-0.4	-0.6	-0.7	-1.1
Hearing difficulty/problems with background noise	0.5	0.7	2.3	-0.7	-1.4	-0.6	-0.9	-0.6	-1.5	-1.1	-0.3	-0.3	-0.4	-0.4
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.3	0.0	-0.7	-1.1	-1.0	-0.5	-0.0	-0.9	-1.1	-0.9	0.1	-0.6
Lung cancer (father)	0.5	0.6	2.5	-1.0	0.7	-0.7	0.8	0.3	-1.6	0.4	-0.6	-0.6	0.4	0.8
Impedance of arm (left)	0.5	2.3	9.0	0.0	2.5	0.9	1.4	3.0	0.7	1.3	-0.6	-2.2	-0.2	0.7
Headache pain in last month	0.5	0.9	2.3	0.1	0.5	1.4	0.7	1.0	1.3	0.0	1.4	0.4	0.8	1.5
Medication: Amlodipine	0.5	0.6	4.8	0.3	-0.3	-0.9	0.3	0.0	-2.2	-0.2	-0.2	0.5	-0.3	0.9
High blood pressure (siblings)	0.5	0.7	2.7	-0.9	-1.4	-0.0	-0.4	-1.0	0.8	-1.6	-0.3	-0.1	0.1	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	3.2	-0.7	-0.3	1.5	0.4	0.4	1.8	-0.5	0.4	0.0	0.6	0.4
Ever had bowel cancer screening	0.5	0.5	2.9	-0.6	0.4	0.1	0.5	0.8	-1.7	-0.0	-0.1	-0.1	-0.2	1.2
Medication for cholesterol	0.5	0.8	3.0	1.3	1.3	0.8	0.5	-0.2	1.0	0.6	-0.4	0.7	1.7	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	1.5	0.5	1.1	-0.7	1.2	0.4	-1.0	0.3	-0.4	-0.6	-0.1	0.8
Medication: Blood pressure	0.5	0.9	3.1	-0.4	-0.6	0.0	1.1	1.6	-0.5	-0.0	0.9	1.0	0.1	1.8
Medication: Atorvastatin	0.5	0.6	1.9	-0.3	0.4	-0.5	1.0	0.1	-1.2	-0.7	0.7	0.2	0.5	1.4
Average weekly beer plus cider intake	0.5	0.8	5.1	0.3	-0.2	-2.3	-0.7	-0.6	-0.0	-0.6	-1.0	-0.8	-0.1	-0.4
Vascular/heart problems diagnosed by doctor	0.5	1.3	5.6	-0.0	0.7	-1.5	-0.5	-1.4	0.5	0.0	-1.5	-1.2	0.1	-2.4
Basal cell carcinoma (self-reported)	0.5	0.6	1.3	1.1	0.9	-0.1	0.1	0.9	0.5	1.0	0.7	0.0	-1.0	-1.1
Impedance of whole body	0.5	2.7	10.9	0.3	2.5	0.6	1.9	3.3	-0.6	1.7	-0.4	-1.7	0.4	1.4
Alzheimer’s Disease (in mother)	0.4	0.5	1.5	0.8	-0.7	-0.7	-0.4	-1.2	1.0	-0.5	0.0	0.3	-0.2	-0.6
Alzheimer’s Disease (in father)	0.4	0.4	1.3	1.1	-0.3	1.0	-1.0	-1.0	-0.2	-0.4	0.2	0.1	-0.2	-0.2
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.0	0.2	0.8	-0.1	0.5	1.4	0.5	0.9	0.8	0.3	0.4	0.4
Systolic Blood Pressure	0.4	2.0	4.2	0.9	1.4	1.4	1.0	1.9	-1.0	1.6	0.6	1.8	1.3	2.0
Hand grip strength (left)	0.4	1.1	4.0	0.9	1.1	-1.8	0.2	-0.8	-0.3	0.6	-2.0	-0.2	0.9	-0.9
Frequency of depressed mood in last 2 weeks	0.4	0.5	3.8	0.3	0.4	2.0	0.3	-0.5	0.8	0.0	0.7	-0.0	0.5	0.2
Ever had hysterectomy (womb removed)	0.4	0.5	1.1	1.1	0.9	-1.0	0.4	0.5	-0.5	0.8	0.6	0.7	0.3	0.4
Vitamin and mineral supplements	0.4	0.5	2.1	0.4	-0.5	-0.2	-1.0	-0.8	0.7	0.1	-0.6	0.5	0.5	-1.5
Supplements: Zinc	0.4	0.5	1.5	0.2	1.2	0.5	1.2	0.0	0.3	0.5	0.8	0.3	0.5	0.9
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	0.7	0.8	-0.1	-0.2	-1.1	-0.0	-0.4	-0.7	-0.6	-0.8	-0.6
High blood pressure	0.4	1.2	4.7	-0.2	-0.9	1.4	0.3	1.1	-0.5	0.0	1.5	1.2	-0.1	2.2
Mouth/teeth dental problems	0.4	0.7	2.0	-0.9	-1.4	-0.5	-0.5	-0.7	-0.4	-1.0	-1.1	-0.4	-1.0	0.2
Heart attack	0.4	0.5	3.3	-0.6	-0.3	1.8	0.2	-0.4	1.0	-0.4	0.8	0.1	-0.3	0.4
Medication: Simvastatin	0.4	0.6	1.5	-1.1	-1.2	1.0	-0.6	-0.4	0.3	-0.4	0.9	0.3	-1.0	-0.1
Illnesses of siblings	0.4	0.5	1.2	0.1	0.5	-0.3	-0.5	0.9	-0.7	1.0	-0.2	-1.0	-1.1	-0.8
Impedance of arm (right)	0.4	1.9	6.9	-0.1	2.2	1.2	1.2	2.6	0.5	1.1	-0.5	-2.2	0.0	0.4
Arm fat percentage (right)	0.4	1.7	3.3	-1.3	-1.8	-0.1	-1.7	-1.8	0.2	-1.4	-0.1	-1.1	-1.6	-1.0
Noisy workplace	0.4	0.5	2.1	-1.0	0.3	1.4	0.2	-0.0	1.0	0.1	0.7	-0.6	-0.5	0.0
Medication: Cholesterol lowering	0.4	0.6	2.1	0.4	0.4	1.5	0.6	0.3	-0.2	0.0	1.2	1.1	0.2	0.9
Medication: Lansoprazole	0.4	0.5	2.1	-0.9	-1.4	0.4	-0.9	-0.7	-0.2	-1.0	-0.2	0.1	-0.4	-0.3
Tense / ‘highly strung’	0.4	0.7	2.7	-0.5	-0.2	1.3	0.1	0.8	0.5	0.4	1.6	0.6	-1.0	0.3
Pulse wave reflection index	0.4	0.4	2.0	-0.9	-0.4	-0.4	-0.4	-0.6	-0.3	-0.5	0.3	-1.4	-0.7	-0.4
Medication: Paracetamol	0.4	0.6	1.9	-0.5	-0.6	1.1	1.0	-0.2	-0.5	-0.6	0.1	0.7	0.8	1.4
Body fat percentage	0.4	1.6	3.1	-1.2	-1.6	-0.7	-1.6	-1.8	-0.4	-1.3	-0.5	-1.4	-1.6	-0.9
Exposure to tobacco smoke outside home	0.4	0.5	3.6	-0.5	-0.2	1.9	-0.4	-0.5	0.4	0.5	0.6	0.6	-0.5	0.1
Emphysema/chronic bronchitis	0.4	0.4	1.6	1.3	0.6	-0.3	0.1	-0.3	1.1	0.5	0.9	0.3	0.4	-0.2
Medication: Ibuprofen	0.4	0.4	1.5	-0.7	-1.1	0.6	-0.0	-0.5	-0.7	-1.2	0.2	-0.3	-0.2	0.6
Pulse rate, automated reading	0.4	1.5	7.5	0.6	-1.1	0.1	-0.9	-2.7	-0.4	-1.5	-1.7	0.2	-0.2	-0.7
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.3	0.1	-0.6	-1.0	-1.1	0.5	-0.2	-1.0	-0.7	-0.9	-0.5	0.6
Medication: Aspirin	0.4	0.5	1.8	-1.3	-0.9	-0.0	-0.7	-0.8	-0.5	-0.6	0.0	-0.1	-0.1	-1.2
Knee pain experienced in last month	0.4	0.6	1.4	0.4	0.8	0.7	0.6	0.9	0.6	0.7	-0.1	1.0	1.2	1.1
Smoking status: Previous	0.4	0.6	1.7	0.8	0.4	-0.1	0.9	0.6	0.7	1.3	0.9	1.2	0.1	0.3
Arm fat percentage (left)	0.4	1.5	2.9	-1.1	-1.6	-0.2	-1.5	-1.7	0.6	-1.4	-0.2	-1.1	-1.6	-1.0
Average weekly red wine intake	0.4	0.5	1.1	-0.3	-1.0	-0.9	-0.9	-0.9	-0.6	-0.6	-1.1	0.0	0.6	-0.2
Loneliness, isolation	0.4	0.6	1.5	-0.8	-1.0	0.8	-0.6	0.4	0.6	-0.5	1.2	-0.8	-0.9	0.2
Friendships satisfaction	0.4	0.5	1.9	0.2	-0.1	-0.8	-1.0	-0.2	0.5	-0.3	-0.6	-0.9	-0.3	-1.4
Asthma (self-reported)	0.4	0.7	3.1	-0.2	0.4	1.1	0.5	-0.5	1.0	0.3	-0.3	1.1	1.8	0.8
Medication: Aspirin	0.4	0.5	1.4	-0.9	-0.8	0.4	-0.8	-1.2	-0.2	-0.7	0.2	0.1	-0.0	-1.1
Ever taken oral contraceptive pill	0.4	0.4	3.1	0.4	0.2	1.8	-0.3	0.3	0.3	0.5	0.1	0.3	0.1	-0.7
Eye problems/disorders: Glaucoma	0.4	0.5	1.8	-0.1	-0.6	-0.3	-0.7	-1.1	0.8	-1.4	-0.4	-0.7	-0.2	-0.2
Medication: Paracetamol	0.4	0.6	1.5	-0.4	-0.8	1.0	1.0	-0.4	-0.6	-0.8	0.1	0.7	0.9	1.2
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.5	-0.7	-0.6	1.6	-0.2	-0.8	0.9	-0.7	0.5	-0.1	-0.4	0.1
Irritable Bowel Disease (IBD)	0.3	0.8	2.3	-1.2	-0.5	-0.9	-0.8	-0.4	-0.6	0.8	0.4	-0.6	-1.0	-1.5
Fasting Glucose	0.3	0.4	0.8	-0.9	-0.3	0.5	-0.5	0.1	-0.5	-0.6	0.6	-0.9	-0.7	-0.6
Neuroticism (2016)	0.3	0.5	1.1	-0.1	0.5	1.1	1.1	0.7	0.8	-0.0	0.7	0.4	0.7	0.5
Schizophrenia (2014)	0.3	0.8	3.7	0.0	-0.0	0.6	1.0	1.3	0.4	0.5	1.9	0.9	0.6	0.3
Blood White Count	0.3	2.3	5.6	-1.4	0.5	2.4	1.4	2.2	1.3	1.9	1.8	1.1	0.7	0.8
Hypothyroidism (self reported)	0.3	0.7	3.8	0.4	-0.7	-1.9	-1.0	-0.1	-0.2	0.0	-0.6	0.5	-0.4	-0.9
Respiratory disease	0.3	0.6	2.1	-0.1	0.4	1.3	0.6	-0.5	1.5	-0.4	-0.0	0.9	0.9	0.8
Hearing difficulty/problems: Yes	0.3	0.4	1.3	0.1	0.3	0.2	1.1	0.5	0.4	0.6	0.7	1.1	0.1	1.0
Maternal smoking around birth	0.3	0.5	1.9	-0.3	0.6	-0.2	0.8	0.2	-1.1	0.6	-1.4	0.0	0.7	0.4
Serious illness, injury or assault to yourself	0.3	0.3	1.6	-0.3	-0.2	-0.1	0.2	-1.3	-0.4	-0.4	-0.7	-0.4	-0.0	-1.0
Past tobacco smoking	0.3	0.5	1.9	-0.8	-0.9	-0.1	-0.7	-0.1	-0.7	-1.4	-0.4	-0.7	0.5	0.1
Hair/balding pattern: Pattern 2	0.3	0.3	1.4	0.5	0.7	1.2	-0.1	-0.8	0.1	0.4	0.5	0.4	0.5	-0.4
Alcohol intake versus 10 years previously	0.3	0.4	2.2	-0.7	-0.4	-0.3	-0.6	-0.7	-0.7	-0.7	-1.5	-0.1	-0.1	-0.0
Father’s age at death	0.3	0.4	1.1	0.1	-0.3	-0.8	0.3	-1.0	-0.7	0.6	-0.9	0.4	-0.2	-0.6
Falls in the last year	0.3	0.4	3.3	-1.8	-0.8	0.4	-0.5	-0.1	-0.3	-0.4	-0.1	-0.2	-0.3	-0.0
Number of live births	0.3	0.4	2.5	1.6	0.2	-0.8	0.1	-0.2	0.7	0.2	0.6	0.6	0.6	0.0
Pulse rate	0.3	0.4	2.2	1.0	0.5	0.8	0.2	-0.6	0.0	0.2	0.4	1.5	0.3	0.0
Asthma	0.3	0.6	2.7	-0.4	0.4	1.0	0.3	-0.7	0.9	0.1	-0.5	0.8	1.6	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.7	-0.7	-0.8	0.2	0.5	0.0	-0.6	-0.8	0.1	-0.6	-0.7	0.8
Prospective memory result	0.3	0.3	1.4	-0.2	-0.5	-0.4	0.2	-0.1	-0.5	-0.3	0.5	-0.9	-1.2	0.5
Pulse wave Arterial Stiffness index	0.3	0.3	1.2	-0.4	-0.7	-0.2	-0.8	-0.6	-0.4	-1.1	-0.1	-0.8	-0.3	-0.4
Peak expiratory flow (PEF)	0.3	0.6	1.4	0.9	0.9	-1.2	0.1	0.3	0.8	0.8	-0.7	-0.0	-0.6	-1.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.2	0.5	-0.7	-1.5	-1.2	0.3	-0.0	0.2	0.1	0.5	-0.5	-1.0
Birth weight	0.3	0.7	4.0	0.6	0.4	-2.0	0.3	-0.5	-0.5	-0.1	-1.7	0.2	0.1	0.0
Number of full brothers	0.3	0.4	2.2	0.4	0.1	0.3	-0.6	-0.4	1.5	-0.3	-0.3	0.4	0.0	-1.0
Age at first live birth	0.3	0.4	1.9	-0.8	-0.2	-0.1	0.1	-1.0	-0.1	0.2	-0.7	-0.8	-0.4	-1.4
Health satisfaction	0.3	0.3	1.1	1.1	0.4	-0.3	0.2	-0.9	-0.4	0.1	-0.7	0.4	0.2	-0.8
Medication: Allopurinol	0.3	0.4	1.0	-1.0	-0.9	1.0	-0.0	0.4	0.5	-0.1	0.9	-0.3	-0.3	-0.4
Hypertension (Self-reported)	0.3	0.9	4.0	-0.1	-0.7	0.9	0.6	1.2	-0.7	-0.1	1.2	0.9	-0.4	2.0
Illnesses of father: Heart disease	0.3	0.4	2.4	-0.4	0.3	-1.5	-0.1	0.3	-0.0	0.8	-0.2	-0.3	-0.9	-0.6
Diabetes diagnosed by doctor	0.3	0.5	2.2	-0.2	-0.2	0.6	0.4	-0.8	0.2	-0.5	1.5	1.0	0.4	0.4
Illnesses of father: None of the above (group 1)	0.3	0.4	1.0	0.8	1.0	0.9	0.7	0.8	0.2	-0.3	-0.1	-0.6	0.5	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.3	0.4	-0.8	-1.2	-0.3	-0.0	-1.5	-1.1	-0.9	0.6	-0.2	0.2
Miserableness	0.3	0.4	1.8	-0.0	0.6	1.3	-0.0	1.3	-0.1	0.7	0.4	-0.1	0.5	0.3
Ever smoked	0.3	0.5	1.6	0.1	0.3	-0.6	-0.2	-0.6	-1.0	0.5	-1.1	-0.4	-1.3	-0.9
Diastolic blood pressure, automated reading	0.3	1.0	2.2	0.1	1.4	1.1	1.5	1.1	0.5	1.2	0.7	0.2	0.1	1.3
Ever depressed for a whole week	0.3	0.4	0.9	-0.4	-0.9	-1.0	-0.9	-0.3	0.4	-0.8	-0.7	-0.3	0.5	-0.1
Unable to work because of sickness or disability	0.3	0.4	1.9	0.2	0.1	1.2	0.2	0.0	1.4	-0.1	0.7	0.6	-0.1	0.7
Commuting to job workplace: Cycle	0.3	0.3	1.3	0.3	0.9	-0.0	-0.0	0.0	1.2	0.4	-0.9	-0.4	0.3	-0.4
Bipolar Disorder or Schizophrenia	0.2	0.4	1.9	-0.8	-0.8	-0.4	-0.2	0.2	-0.6	-0.3	1.4	-0.3	-0.4	-0.5
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.4	1.6	0.0	-1.4	0.4	0.2	0.1	0.4	-0.4	0.6	0.5	-0.5
Reaction Time	0.2	0.4	0.7	-0.5	0.4	0.4	-0.7	0.8	-0.4	0.8	-0.7	-0.6	-0.7	-0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.3	-0.2	-1.0	-1.1	-0.1	0.1	-0.2	-0.6	-1.1	0.2	0.3	-0.4
Rheumatoid Arthritis	0.2	0.3	1.1	0.3	-0.2	0.0	0.1	0.9	1.1	-0.0	1.0	0.1	0.6	0.1
Smoking Status	0.2	0.5	1.8	-0.3	-0.4	-1.1	-1.1	-0.3	0.3	0.1	-1.3	0.2	-0.6	-0.7
Hair Pigment	0.2	4.8	11.4	0.6	2.8	2.0	2.2	3.4	0.2	3.1	0.9	1.6	2.8	2.0
Townsend deprivation index at recruitment	0.2	0.3	1.1	-0.1	0.4	0.3	0.1	-1.0	0.3	-0.8	-0.2	-0.7	-0.4	-0.3
Multivitamins +/- minerals	0.2	0.3	0.7	-0.9	-0.3	-0.3	0.1	0.2	-0.8	-0.7	-0.2	-0.7	-0.5	0.6
Fluid intelligence score	0.2	0.5	1.1	-0.4	-1.0	-0.8	-1.0	-0.1	-0.1	-0.3	-1.0	0.3	-0.5	-1.1
Time employed in main current job	0.2	0.2	0.8	-0.2	0.4	0.3	0.4	-0.6	0.3	0.3	0.4	0.9	0.7	0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.0	-1.0	-0.5	-0.5	0.0	-0.9	-0.0	-0.5	-0.7	-0.7	-0.1	-0.8
Mouth/teeth dental problems: Dentures	0.2	0.3	0.7	-0.2	-0.1	-0.4	-0.8	-0.7	-0.8	-0.8	-0.2	-0.5	-0.2	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.5	-0.0	-0.9	-0.2	-0.7	-0.9	-1.1	-0.9	-1.2	0.6	0.2	-0.2
Breastfed as a baby	0.2	0.3	1.1	-0.5	-0.2	0.8	0.3	-0.3	-0.6	-0.0	-0.4	-0.0	0.4	1.0
Birth weight of first child	0.2	0.3	0.8	-0.6	-0.7	-0.5	-0.7	-0.1	-0.4	-0.0	-0.5	-0.7	-0.9	-0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.4	-0.5	-0.4	-1.2	-0.1	-0.0	0.4	0.1	-0.4	-0.8	0.4	-0.3
Forced vital capacity (FVC), Best measure	0.2	0.7	2.7	0.7	-0.4	-0.2	-0.3	-0.6	-1.5	-0.4	-1.6	0.8	0.6	0.4
Qualifications: College or University degree	0.2	0.5	2.3	0.4	0.7	0.7	0.9	0.5	-0.4	1.5	0.5	0.8	0.4	-0.0
Medication: Blood pressure	0.2	0.4	0.8	0.8	-0.1	0.9	0.0	-0.1	-0.8	-0.5	0.6	0.9	0.0	0.9
Mean time to correctly identify matches	0.2	0.3	1.2	-0.2	0.3	0.1	-0.1	1.1	-1.1	0.5	-0.4	0.1	0.0	0.7
Alcohol intake frequency.	0.2	0.4	1.1	-0.8	-1.1	0.9	-0.2	0.5	0.1	-0.8	0.8	0.4	-0.1	0.3
Family relationship satisfaction	0.2	0.3	1.4	-0.0	-0.3	-0.7	-0.6	-0.1	1.2	-0.4	-0.1	-0.1	-0.4	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	2.0	1.4	0.5	-0.4	0.1	0.5	0.3	-0.1	0.8	-0.3	0.1	-0.2
Average weekly champagne plus white wine intake	0.2	0.2	0.7	0.8	-0.3	0.6	-0.2	-0.0	0.6	0.2	-0.1	0.1	-0.8	-0.5
Commuting to job workplace: Public transport	0.2	0.2	0.9	0.2	0.7	-0.2	0.3	-0.9	-0.4	0.0	-0.7	-0.1	0.1	0.2
Age started oral contraceptive pill	0.2	0.2	0.6	0.7	0.2	-0.7	0.4	0.5	-0.6	0.3	0.4	0.6	0.2	0.1
Myopia	0.2	0.3	1.2	0.3	0.3	-0.1	0.5	0.4	-0.0	0.4	-0.2	0.4	0.9	1.1
Crohns Disease (2017)	0.1	0.3	1.0	-0.3	-0.2	-0.3	-0.8	0.1	0.8	0.7	0.3	-0.2	-0.2	-1.0
Blood Eosinophil Count	0.1	1.1	4.1	1.1	0.1	0.2	-0.3	1.2	0.7	0.9	2.0	1.8	0.3	0.3
Blood Platelet Count	0.1	1.2	2.9	-0.5	1.1	-1.7	1.6	1.5	0.2	1.6	-0.7	-0.5	-0.0	-0.9
Blood Red Count	0.1	1.2	3.3	-1.2	-1.8	1.1	-1.3	0.8	-0.0	-0.4	1.5	-0.4	-1.7	0.1
Waist Hip Ratio (WHR)	0.1	0.5	2.2	-0.9	-0.0	0.0	0.3	0.3	0.2	0.6	-0.4	1.0	1.5	0.9
Allergy or Eczema	0.1	0.4	1.2	-0.4	0.6	0.8	0.1	0.8	-0.5	0.6	-0.1	0.5	0.1	1.1
Average weekly spirits intake	0.1	0.1	0.4	-0.2	0.2	0.4	-0.2	-0.2	0.6	-0.1	0.2	0.0	-0.3	0.0
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	1.2	0.6	0.3	0.2	0.0	-0.0	0.3	-0.1	1.1	0.3	0.2	0.1
Medication for hormone replacement therapy	0.1	0.1	0.3	0.3	-0.2	-0.1	0.2	0.0	-0.5	-0.3	0.5	-0.1	-0.0	-0.1
Diabetes (father)	0.1	0.1	0.7	0.0	-0.4	-0.4	-0.3	-0.8	0.5	-0.4	-0.1	0.1	-0.1	-0.3
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.7	-0.8	-0.3	-0.2	-1.3	0.3	-0.4	0.3	-0.4	0.1	-0.7	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.5	-0.6	-0.6	0.5	-0.0	0.2	-0.1	-0.3	0.7	0.3	0.1	-0.3
Alcohol usually taken with meals	0.1	0.1	0.7	0.0	-0.0	0.5	0.0	0.8	-0.1	0.4	0.5	-0.3	0.2	0.0
Forced vital capacity (FVC)	0.1	0.6	2.0	1.0	0.2	-0.7	-0.0	0.0	-1.0	0.1	-1.4	1.1	0.6	0.4
Allergy	0.1	0.2	0.7	0.8	0.3	-0.3	0.7	-0.1	-0.2	0.1	-0.0	-0.7	-0.1	-0.7
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	1.3	0.5	-0.2	-0.7	-0.2	-0.1	-0.3	-0.2	-1.0	1.2	0.4	-0.1
Leg fat percentage (right)	0.1	0.4	1.3	0.0	-0.9	-0.7	-0.7	-1.2	-0.3	-0.3	0.2	-0.2	-0.8	-0.3
Pulse wave peak to peak time	0.1	0.2	0.7	0.2	0.5	-0.0	0.6	0.3	0.4	0.8	-0.3	0.5	0.2	0.1
Osteoporosis (self-reported)	0.1	0.1	0.7	-0.3	-0.1	-0.2	-0.1	0.2	-0.1	0.1	0.8	-0.1	-0.4	-0.1
Wears glasses or contact lenses	0.1	0.2	0.5	0.3	0.7	-0.5	-0.0	0.2	0.6	0.5	-0.1	-0.2	0.3	-0.4
Leg fat percentage (left)	0.1	0.4	1.4	-0.1	-1.2	-0.5	-0.8	-1.1	-0.4	-0.4	0.5	-0.1	-0.8	-0.1
Irritability	0.1	0.2	0.5	-0.6	-0.2	-0.2	0.1	-0.3	-0.7	-0.2	-0.2	-0.6	-0.5	-0.5
Risk taking	0.1	0.2	1.2	0.2	0.9	-0.1	1.1	-0.2	0.2	0.4	0.2	0.1	-0.1	0.1
Tanning	0.0	0.5	2.0	0.8	-0.6	-0.6	-0.4	-0.5	-0.0	-1.0	-0.4	1.4	0.6	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.1	0.3	0.2	-0.2	0.0	-0.3	-0.3	0.0	0.0	0.1	0.5	0.2	-0.1

Hub : Genes

SCFD2

Models

Trait associations