Best TWAS P=7.48e-39 · Best GWAS P=7.99e-40 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C4orf22 | 0.09 | 0.08 | lasso | 5 | 0.07 | 4.5e-09 | 13.0 | 13.0 | 7.5e-39 | 0.96 | 0.01 | 0.99 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | FGF5 | 0.07 | 0.06 | lasso | 2 | 0.05 | 5.4e-07 | 13.0 | 12.2 | 4.3e-34 | 0.92 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Nerve Tibial | PRDM8 | 0.14 | 0.14 | lasso | 3 | 0.13 | 1.0e-09 | 5.6 | 5.6 | 1.6e-08 | 0.23 | 1.00 | 0.00 | TRUE |
| 4 | GTEx | Ovary | PRDM8 | 0.49 | 0.01 | lasso | 7 | 0.16 | 9.4e-05 | 10.8 | 5.7 | 1.3e-08 | 0.29 | 0.05 | 0.07 | FALSE |