[Hub]/) : Traits : Hair/balding pattern: Pattern 4 :

chr1:168,932,500-171,407,761

Best TWAS P=9.19e-36 · Best GWAS P=2.59e-44 conditioned to 0.578

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GORAB 0.14 0.12 lasso 8 0.14 9.9e-17 -5.6 10.3 4.4e-25 0.60 0.98 0.02 FALSE
2 CommonMind Brain Pre-frontal Cortex KIFAP3 0.08 0.06 lasso 5 0.06 1.8e-07 5.3 -5.5 3.3e-08 -0.09 1.00 0.00 TRUE
3 GTEx Artery Aorta C1orf112 0.10 0.00 enet 15 0.01 1.4e-01 4.2 6.2 6.1e-10 0.34 0.14 0.34 FALSE
4 GTEx Cells Transformed fibroblasts KIFAP3 0.14 0.05 lasso 20 0.13 7.0e-10 -1.1 -8.5 1.5e-17 -0.36 0.98 0.01 FALSE
5 GTEx Cells Transformed fibroblasts PRRX1 0.07 0.06 lasso 4 0.06 3.7e-05 -7.3 -9.0 2.4e-19 -0.61 0.85 0.05 TRUE
6 GTEx Heart Left Ventricle GORAB 0.16 0.08 enet 22 0.03 6.9e-03 -4.9 7.0 3.3e-12 0.27 0.20 0.22 FALSE
7 GTEx Lung GORAB 0.15 0.08 enet 23 0.10 6.2e-08 -4.9 8.7 2.4e-18 0.52 0.51 0.36 FALSE
8 GTEx Nerve Tibial GORAB 0.09 0.02 enet 7 0.02 1.3e-02 -6.8 5.2 1.9e-07 0.16 0.21 0.03 TRUE
9 GTEx Pituitary GORAB 0.22 0.09 lasso 7 0.10 2.0e-03 12.2 12.5 9.2e-36 0.83 0.06 0.64 TRUE
10 GTEx Skin Sun Exposed Lower leg GORAB 0.07 0.01 lasso 5 0.00 4.2e-01 12.3 9.8 1.3e-22 0.74 0.06 0.33 FALSE
11 GTEx Uterus SCYL3 0.29 0.16 lasso 11 0.12 1.7e-03 -5.4 -5.2 1.5e-07 -0.02 0.14 0.08 TRUE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma GORAB 0.09 0.05 lasso 1 0.03 5.5e-03 -5.7 5.7 1.4e-08 0.25 0.03 0.17 TRUE
13 The Cancer Genome Atlas Prostate Adenocarcinoma GORAB 0.07 0.01 blup 33 0.05 6.6e-06 -6.8 9.9 3.2e-23 0.61 0.01 0.94 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma GORAB 0.11 0.07 enet 7 0.07 2.3e-07 -5.0 8.6 1.0e-17 0.52 0.60 0.29 TRUE