Best TWAS P=4.09e-45 · Best GWAS P=3.74e-150 conditioned to 7.02e-113
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | TCF7L2 | 0.19 | 0.09 | lasso | 6 | 0.05 | 0.001 | 14.25 | -14.1 | 4.1e-45 | -0.69 | 0.87 | 0.04 | TRUE |
2 | NTR | Blood | VTI1A | 0.02 | 0.00 | blup | 610 | 0.00 | 0.011 | 0.39 | -9.1 | 9.7e-20 | -0.40 | 0.04 | 0.09 | FALSE |