Best TWAS P=6.28e-10 · Best GWAS P=4.78e-16 conditioned to 7.25e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATXN2 | 0.02 | 0.03 | enet | 8 | 0.02 | 4.8e-04 | -4.0 | 5.2 | 1.5e-07 | 0.57 | 0.22 | 0.70 | FALSE |
| 2 | GTEx | Artery Tibial | HECTD4 | 0.05 | 0.02 | lasso | 3 | 0.01 | 3.1e-02 | 6.4 | 5.8 | 7.9e-09 | 0.81 | 0.02 | 0.90 | FALSE |
| 3 | YFS | Blood | SH2B3 | 0.05 | 0.01 | enet | 22 | 0.02 | 3.3e-07 | -3.9 | 6.2 | 6.3e-10 | 0.66 | 0.38 | 0.62 | TRUE |