Best TWAS P=2.62e-32 · Best GWAS P=4.21e-33 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C11orf63 | 0.12 | 0.11 | lasso | 5 | 0.10 | 2.3e-08 | 11.0 | -10.8 | 2.2e-27 | 0.79 | 0.96 | 0.03 | FALSE |
| 2 | GTEx | Nerve Tibial | C11orf63 | 0.24 | 0.08 | enet | 18 | 0.22 | 6.2e-16 | 3.9 | -10.1 | 5.1e-24 | 0.57 | 0.39 | 0.61 | TRUE |
| 3 | GTEx | Testis | C11orf63 | 0.32 | 0.14 | lasso | 7 | 0.08 | 3.2e-04 | -11.5 | 11.8 | 2.6e-32 | -0.97 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | CRTAM | 0.10 | 0.04 | enet | 6 | 0.05 | 1.1e-03 | 4.0 | -6.8 | 9.4e-12 | 0.30 | 0.01 | 0.89 | FALSE |