Hub : Genes

WARS

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Testis	0.5900	0.0590	0.0e+00	0.517	NA	0.549	NA	0.544	2.5e-26	NA	1.3e-28	NA	2.8e-28
2	GTEx	Whole Blood	0.1160	0.0320	3.8e-06	0.073	NA	0.072	NA	0.074	2.8e-07	NA	3.3e-07	NA	2.5e-07
3	NTR	Blood	0.1091	0.0180	0.0e+00	0.163	0.140	0.165	0.166	0.167	2.8e-50	8.5e-43	6.2e-51	5.2e-51	1.6e-51
4	YFS	Blood	0.2656	0.0290	0.0e+00	0.396	0.391	0.406	0.291	0.403	1.4e-140	5.4e-138	6.3e-145	1.6e-96	1.7e-143
5	TCGA	Breast Invasive Carcinoma	0.0271	0.0129	2.5e-04	0.000	0.010	0.004	NA	0.004	3.5e-01	2.7e-03	3.5e-02	NA	5.1e-02
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0230	0.0145	6.5e-03	0.030	0.008	0.009	NA	0.016	2.4e-04	3.5e-02	2.7e-02	NA	5.6e-03
7	TCGA	Brain Lower Grade Glioma	0.0441	0.0234	3.3e-03	0.026	0.003	0.004	NA	0.001	5.7e-04	1.4e-01	1.1e-01	NA	2.1e-01
8	TCGA	Thyroid Carcinoma	0.0280	0.0140	8.0e-04	0.039	0.034	0.039	NA	0.032	1.0e-04	2.8e-04	9.9e-05	NA	3.7e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.1	1.7	4.1	1.2	1.0	1.4	1.3	2.0	-1.0	-0.7	1.3
Bipolar Disorder or Schizophrenia	0.4	1.0	2.3	1.2	1.1	1.0	1.0	1.5	-0.6	0.2	0.9
Depressed Affect (Nagel 2018)	0.1	0.2	1.1	-0.6	-0.4	0.0	0.0	-0.1	-0.5	-1.0	0.2
Depression (Nagel 2018)	0.8	1.2	2.4	0.6	0.7	1.0	1.0	1.2	-1.2	-1.6	1.1
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.0	0.1	0.7	0.8	0.7	-1.0	-1.4	-1.2	1.0
Neuroticism (Nagel 2018)	0.2	0.4	1.0	-0.1	-0.1	0.5	0.5	1.0	-0.7	-1.0	0.6
Schizophrenia (2018)	0.1	0.2	0.6	0.5	0.5	0.1	0.2	0.2	-0.0	0.8	0.1
Schizophrenia vs Biploar Disorder	0.1	0.1	0.4	-0.4	-0.5	-0.2	-0.2	0.0	0.0	-0.6	-0.2
Worry (Nagel 2018)	1.6	3.3	4.2	1.7	1.7	2.0	2.0	1.8	-2.0	-1.1	2.0
Alzheimer’s Disease (in mother)	0.0	0.1	0.1	0.2	0.2	-0.2	-0.2	0.3	0.3	0.3	-0.2
Alzheimer’s Disease (in father)	0.7	0.8	1.8	-0.5	-1.0	-0.7	-0.8	0.6	1.3	0.7	-0.9
Alzheimer’s Disease (including proxy)	0.1	0.2	0.6	0.2	-0.0	-0.2	-0.3	0.6	0.6	0.7	-0.3
Crohns Disease (2017)	0.6	1.3	2.5	0.6	0.7	1.3	1.1	0.8	-1.4	-1.6	1.3
Irritable Bowel Disease (IBD)	0.0	0.1	0.3	-0.5	-0.3	0.1	0.0	-0.3	-0.4	-0.5	0.1
Ulcerative Colitis (UC)	0.2	0.4	0.7	-0.8	-0.8	-0.6	-0.6	-0.8	0.4	0.6	-0.6
Major Depression (MDD)	6.0	7.3	10.1	-3.2	-3.1	-3.1	-3.2	-1.7	2.7	0.6	-3.0
Reaction Time	1.0	2.0	2.7	-1.6	-1.5	-1.6	-1.6	-0.5	1.6	0.8	-1.6
Verbal and Numeric Reasoning (VNR)	0.3	0.6	2.4	-1.0	-0.6	-0.4	-0.5	-0.8	-0.2	-1.5	-0.3
Breast Cancer	0.0	0.1	0.2	-0.3	-0.3	-0.3	-0.3	-0.5	0.3	-0.1	-0.3
Ovarian Cancer	0.2	0.3	1.0	0.1	0.2	-0.3	-0.5	-0.5	0.5	1.0	-0.4
Prostate Cancer	0.6	0.8	2.1	0.6	1.2	0.7	0.7	-1.4	-1.0	0.4	0.8
Age at First Birth	0.1	0.2	0.5	0.1	0.7	0.2	0.3	-0.5	-0.3	0.7	0.2
Bipolar Disorder (2011)	1.9	1.9	12.1	0.0	0.0	0.0	0.0	3.5	-0.9	0.0	1.5
Body Mass Index (BMI) (2010)	0.3	0.3	0.6	-0.6	-0.8	-0.5	-0.7	-0.6	0.3	-0.7	-0.4
Coronary Artery Disease (CAD)	5.2	6.2	9.9	-1.9	-2.7	-2.5	-2.7	0.1	3.1	2.8	-2.8
Crohns Disease (2012)	0.1	0.1	0.2	-0.4	-0.0	0.4	0.2	-0.0	-0.4	-0.3	0.4
Mean Putamen Volume	3.2	3.7	4.7	-1.8	-1.8	-2.1	-2.2	-1.3	2.1	1.8	-2.2
Fasting Glucose	5.1	6.1	9.4	-2.7	-2.3	-3.1	-2.9	-1.2	2.9	0.1	-3.0
HbA1C	1.2	1.3	2.1	-1.4	-1.4	-1.1	-1.3	-0.7	1.2	0.7	-1.1
HDL Cholesterol	4.6	7.7	13.7	2.4	2.6	3.0	3.2	3.7	-2.4	-1.7	2.8
LDL Cholesterol	6.9	11.0	16.5	-3.2	-2.4	-3.3	-3.6	-4.1	2.8	3.6	-3.2
Lupus	4.8	7.3	10.9	-2.8	-3.2	-3.1	-2.9	-0.5	3.3	0.8	-3.2
Neuroticism (2016)	1.3	1.9	2.4	1.2	1.5	1.4	1.5	1.2	-1.4	-1.2	1.5
Primary Biliary Cirrhosis	0.6	0.9	1.4	-1.1	-0.8	-1.1	-1.2	-0.8	1.0	0.0	-1.0
Rheumatoid Arthritis	0.5	0.7	1.7	0.9	1.3	0.8	0.8	0.8	-0.3	0.7	0.6
Schizophrenia (2014)	0.6	1.3	2.6	1.5	1.2	1.1	1.1	1.6	-0.8	0.2	1.0
Triglycerides	3.6	5.9	9.1	-2.6	-3.0	-2.5	-2.9	-2.9	1.7	-0.3	-2.3
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.9	-0.9	-1.4	-0.7	-0.5	0.2	0.3	0.0	-0.6
Ulcerative Colitis	0.7	1.0	1.0	-1.0	-1.0	-1.0	-1.0	-0.8	1.0	1.0	-1.0
Blood Eosinophil Count	0.2	1.2	2.9	-1.0	-0.4	-1.0	-1.1	-1.7	0.7	1.3	-0.9
Blood Platelet Count	0.0	0.1	0.2	0.3	-0.5	0.3	0.0	0.0	-0.1	0.2	0.3
Blood Red Count	0.1	0.6	1.1	0.8	0.5	0.8	0.6	-0.9	-1.0	-0.7	0.8
Blood White Count	0.1	0.7	2.1	1.2	1.2	0.4	0.2	-0.4	-0.1	1.4	0.3
Heel T-Score	0.4	3.2	4.9	-2.2	-1.9	-2.1	-1.8	-1.1	1.8	0.8	-2.0
BMI	0.4	2.2	4.5	-1.5	-1.8	-1.2	-1.4	-2.1	0.3	-1.8	-1.0
Height	0.1	1.4	4.8	-1.0	-0.3	-1.1	-0.8	-1.3	0.8	2.2	-1.1
Waist Hip Ratio (WHR)	0.1	0.3	1.5	-0.1	0.2	-0.3	-0.4	-1.2	0.3	0.8	-0.3
Systolic Blood Pressure	1.7	8.6	11.9	-2.7	-3.3	-3.2	-3.4	-1.7	3.4	1.8	-3.3
Smoking Status	0.1	0.2	0.4	0.4	0.4	-0.2	-0.5	-0.7	0.5	0.6	-0.3
Allergy or Eczema	0.3	0.7	4.5	-0.1	0.3	0.4	0.4	0.2	-0.7	-2.1	0.6
Cardiovascular Disease	3.0	9.9	13.6	-3.7	-3.5	-3.4	-3.7	-3.0	2.8	0.4	-3.3
Hypothyroidism (self reported)	1.2	2.8	3.6	1.7	1.7	1.9	1.9	1.1	-1.8	-1.3	1.9
Respiratory disease	0.2	0.5	1.4	0.5	1.0	0.4	0.3	-0.8	-0.5	1.2	0.4
Type 2 Diabetes (T2D) (2018)	1.0	1.9	2.6	-1.4	-1.5	-1.5	-1.6	-1.4	1.4	0.3	-1.4
Lung FEV1/FVC ratio	0.9	4.4	6.6	-1.8	-2.4	-2.4	-2.6	-1.6	2.3	0.7	-2.4
Lung FVC	1.3	6.8	17.0	1.2	1.2	2.4	2.8	2.7	-2.8	-4.1	2.6
Neuroticism	0.1	0.3	1.1	-0.2	-0.6	0.1	0.1	0.8	-0.3	-1.0	0.1
Chronotype (morning person)	6.7	15.4	21.5	4.6	4.0	4.4	4.3	1.9	-4.4	-2.3	4.5
Hair Pigment	0.0	0.5	2.2	0.4	-0.0	-0.3	-0.3	1.5	1.1	0.7	-0.5
Tanning	0.0	0.5	1.2	1.1	0.6	0.9	0.7	0.5	-0.5	0.3	0.8
Hand grip strength (left)	0.0	0.1	0.5	0.3	-0.0	0.1	0.2	0.7	0.0	0.4	0.0
Number of treatments/medications taken	0.8	1.4	3.3	-1.6	-1.3	-1.0	-1.0	-0.9	0.3	-1.8	-0.8
Average weekly spirits intake	0.3	0.4	1.0	1.0	0.7	0.3	0.4	0.9	0.1	0.9	0.2
Sensitivity / hurt feelings	0.3	0.4	1.0	0.5	0.6	0.7	0.6	1.0	-0.5	-0.6	0.7
Frequency of depressed mood in last 2 weeks	1.9	2.6	3.1	1.5	1.4	1.7	1.7	1.8	-1.8	-1.4	1.7
Hearing difficulty/problems: Yes	1.6	2.4	5.0	-1.2	-1.5	-1.6	-1.8	-2.2	1.4	0.7	-1.5
Relative age of first facial hair	3.9	8.1	13.0	3.6	3.5	3.2	3.2	1.5	-2.7	0.6	3.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	0.1	-0.2	-0.2	-0.1	0.5	0.4	0.3	-0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.8	0.6	0.6	0.6	0.8	1.3	-0.4	-0.2	0.6
Ever had hysterectomy (womb removed)	0.1	0.2	1.1	0.2	0.0	-0.2	-0.3	-1.0	0.1	0.1	-0.2
Systolic blood pressure, automated reading	1.7	4.8	6.7	-1.7	-2.2	-2.4	-2.6	-1.8	2.6	1.6	-2.4
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	5.1	-2.0	-2.2	-2.1	-2.0	-0.9	1.9	0.5	-2.1
Angina	0.7	0.9	1.2	-0.6	-1.0	-1.0	-1.1	-0.9	1.1	0.6	-1.1
Medication for hormone replacement therapy	1.2	1.3	2.5	1.6	0.8	1.2	1.3	1.5	-0.8	0.6	1.1
Vitamin and mineral supplements	0.6	0.8	0.9	-0.9	-0.9	-1.0	-0.9	-0.7	0.9	0.8	-1.0
Supplements: Zinc	0.8	0.9	3.2	-0.9	-0.6	-0.8	-0.8	-1.8	0.4	1.0	-0.7
Medication: Co-codamol	1.5	1.7	2.3	1.2	1.0	1.4	1.3	0.7	-1.5	-1.5	1.5
Medication: Metformin	0.3	0.5	1.4	-0.6	-0.6	-0.6	-0.8	-1.2	0.4	-0.6	-0.5
Diabetes (father)	0.5	0.6	1.8	-0.1	0.5	0.6	0.7	-0.0	-1.1	-1.3	0.8
Diabetes (mother)	0.0	0.0	0.1	-0.0	0.1	0.1	0.1	0.1	-0.2	0.3	0.1
Severe depression (siblings)	0.2	0.2	0.3	0.3	0.5	0.5	0.4	-0.2	-0.4	0.4	0.5
Pack years adult smoking proportion	0.2	0.3	2.0	0.5	0.5	0.1	-0.0	-0.1	-0.0	1.4	0.0
Impedance of leg (right)	1.5	7.2	11.2	3.3	3.3	2.7	2.9	2.6	-2.0	1.4	2.6
Leg fat-free mass (left)	1.1	5.7	8.9	-3.0	-2.6	-2.5	-2.6	-2.8	1.8	0.5	-2.4
Trunk fat percentage	0.3	1.3	3.1	1.8	1.3	1.2	1.0	0.3	-1.1	0.3	1.2
Hand grip strength (right)	0.2	0.7	0.9	1.0	0.9	0.9	1.0	0.5	-0.9	0.3	0.9
Townsend deprivation index at recruitment	0.9	1.3	2.9	-0.9	-0.6	-1.1	-1.2	-1.7	1.0	1.2	-1.1
Current tobacco smoking	0.4	0.6	3.1	-0.0	-0.0	-0.3	-0.6	0.4	0.9	1.8	-0.5
Average weekly fortified wine intake	1.4	1.7	5.0	-0.6	-0.4	-1.1	-1.0	-2.2	1.0	1.9	-1.1
Maternal smoking around birth	1.3	1.8	3.8	-1.2	-0.7	-1.4	-1.4	-0.9	1.4	1.9	-1.4
Fed-up feelings	0.4	0.7	1.2	0.4	0.2	0.8	0.9	1.1	-0.9	-1.0	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	3.0	0.8	1.0	1.2	1.2	0.9	-1.6	-1.7	1.3
Relative age voice broke	1.2	1.8	3.5	1.7	1.9	1.3	1.4	0.4	-0.9	1.2	1.2
Taking other prescription medications	0.7	1.1	2.0	0.9	0.9	1.0	1.0	1.3	-1.0	-1.4	1.0
Age when periods started (menarche)	6.2	14.8	26.5	5.0	5.1	3.7	3.6	-0.7	-2.9	4.3	3.5
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	3.6	0.6	-0.1	0.7	0.7	1.0	-0.9	-1.9	0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.6	5.4	-2.3	-2.1	-2.2	-2.0	-0.6	2.0	0.6	-2.2
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	3.2	-1.8	-1.7	-1.4	-1.4	0.3	1.2	-0.5	-1.4
Qualifications: CSEs or equivalent	0.1	0.1	0.6	-0.1	-0.4	-0.3	-0.2	0.7	0.3	-0.2	-0.3
Serious illness, injury or assault to yourself	0.3	0.4	1.4	-0.2	0.1	0.3	0.3	-0.6	-0.9	-1.2	0.5
High blood pressure	3.9	11.0	15.0	-3.7	-3.8	-3.7	-3.9	-2.6	3.2	0.6	-3.6
Hayfever, allergic rhinitis or eczema	0.5	1.2	5.8	0.2	0.5	0.7	0.7	0.3	-1.1	-2.4	0.9
Multivitamins +/- minerals	0.1	0.1	0.4	-0.6	-0.4	-0.4	-0.3	-0.1	0.4	0.1	-0.4
Stomach or abdominal pain in last month	0.2	0.3	1.2	-0.5	-0.5	-0.2	-0.3	0.7	0.1	-1.1	-0.1
Supplements: Glucosamine	0.3	0.3	1.5	-0.6	-0.5	-0.3	-0.2	0.5	0.1	-1.2	-0.3
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	0.8	-0.9	-0.6	-0.8	-0.8	-0.2	0.8	0.7	-0.8
Medication: Atenolol	1.0	1.2	2.5	-1.6	-1.4	-1.1	-1.1	-0.5	0.8	-0.9	-1.0
Medication: Levothyroxine sodium	0.5	0.8	1.9	1.0	0.6	1.0	0.9	1.4	-0.5	-0.1	0.9
Sitting height	0.9	6.1	8.4	-2.6	-2.9	-2.6	-2.5	-0.3	2.9	2.1	-2.8
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	-0.1	0.4	0.1	0.3	-0.5	-0.3	-0.3	0.2
High blood pressure (mother)	0.1	0.1	0.5	0.1	-0.0	0.2	-0.1	-0.1	-0.2	-0.7	0.1
Body mass index (BMI)	0.2	1.0	2.5	-0.9	-1.1	-0.9	-1.2	-1.6	0.4	-0.9	-0.8
Impedance of leg (left)	2.1	10.2	16.5	4.1	3.8	3.2	3.4	3.7	-2.1	1.6	3.0
Leg predicted mass (left)	1.1	5.9	9.2	-3.0	-2.7	-2.6	-2.7	-2.8	1.9	0.5	-2.4
Trunk fat mass	0.0	0.2	0.7	0.2	-0.0	-0.1	-0.3	-0.8	0.0	0.8	-0.1
Waist circumference	0.1	0.3	2.1	-0.2	-0.1	-0.1	-0.3	-1.5	-0.3	-0.2	0.0
Number of incorrect matches in round	1.5	2.5	3.7	-1.8	-1.7	-1.6	-1.6	0.3	1.9	1.4	-1.7
Past tobacco smoking	0.2	0.3	1.3	-0.9	-1.1	-0.3	-0.3	0.6	0.2	-0.3	-0.3
Alcohol usually taken with meals	2.9	4.8	10.8	-3.3	-2.4	-2.3	-2.2	-2.1	1.5	-0.1	-2.1
Nervous feelings	2.0	3.7	4.6	1.7	1.8	2.0	2.1	1.7	-2.2	-1.5	2.1
Frequency of tenseness / restlessness in last 2 weeks	4.0	6.3	7.3	2.5	2.7	2.7	2.6	2.2	-2.7	-1.8	2.7
Hearing difficulty/problems with background noise	1.3	2.1	3.2	-1.6	-1.5	-1.5	-1.8	-0.9	1.6	0.9	-1.6
Hair/balding pattern: Pattern 2	0.1	0.2	0.9	-0.4	0.1	-0.2	-0.1	0.1	0.4	1.0	-0.3
Had menopause	0.3	0.4	2.3	-0.2	-0.3	-0.5	-0.3	-1.5	-0.1	-0.1	-0.3
Had other major operations	0.5	0.6	1.7	0.3	0.5	0.8	0.8	-0.4	-1.3	-0.6	1.0
Forced vital capacity (FVC)	0.1	0.4	1.5	-0.9	-0.7	-0.3	0.2	1.2	0.1	-0.4	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.2	5.2	-2.3	-2.0	-2.1	-2.0	-0.9	1.8	0.1	-2.0
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.5	-0.6	-0.7	-0.6	-0.5	-0.5	0.4	-0.6	-0.5
Qualifications: None of the above	0.3	0.6	2.1	0.9	0.4	-0.0	-0.0	1.4	0.6	1.2	-0.2
Financial difficulties in last 2 years	0.2	0.3	0.9	0.6	1.0	0.5	0.6	0.1	-0.4	0.5	0.5
Mouth/teeth dental problems	0.0	0.0	0.2	0.2	-0.2	-0.1	0.1	0.2	-0.1	-0.5	-0.0
Heart attack	0.9	1.2	2.1	-0.9	-0.9	-1.1	-1.0	-1.0	1.1	1.5	-1.1
Allergy	0.2	0.4	0.8	-0.5	-0.9	-0.7	-0.5	-0.0	0.8	0.8	-0.7
Pain all over the body in last month	0.0	0.0	0.2	0.3	0.1	0.1	0.1	0.1	-0.2	-0.4	0.1
Diabetes (self-reported)	0.9	1.4	2.2	-1.2	-1.5	-1.2	-1.3	-1.3	1.0	-0.5	-1.2
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.5	-0.0	0.2	0.8	0.9	0.4	-1.1	-1.9	0.9
Medication: Ramipril	0.2	0.3	0.7	0.2	-0.7	-0.4	-0.5	0.0	0.7	0.8	-0.5
Medication: Simvastatin	0.5	0.7	3.1	-0.8	-1.1	-0.4	-0.4	-0.3	-0.1	-1.8	-0.3
Fluid intelligence score	0.2	0.3	1.7	-0.2	0.1	0.3	0.3	-0.2	-0.7	-1.3	0.4
Illnesses of siblings	3.7	5.2	8.8	2.2	2.3	2.4	2.7	3.0	-1.9	-0.7	2.3
Neuroticism score	0.5	1.1	1.9	0.6	0.6	1.0	1.0	1.2	-1.2	-1.4	1.1
Weight	0.6	2.7	3.7	-1.8	-1.8	-1.8	-1.9	-1.9	1.3	0.6	-1.7
Impedance of arm (right)	1.8	8.3	13.5	3.7	3.4	3.0	3.2	3.1	-2.2	0.7	2.8
Arm fat percentage (right)	0.0	0.1	0.5	0.5	-0.1	0.2	-0.1	-0.1	-0.3	-0.7	0.2
Trunk fat-free mass	2.1	12.3	20.3	-4.5	-4.0	-3.8	-3.8	-3.1	3.1	1.0	-3.7
Hip circumference	0.1	0.2	0.8	-0.5	-0.6	-0.3	-0.5	-0.9	-0.0	-0.2	-0.2
Time employed in main current job	1.4	1.6	2.3	1.5	1.4	1.3	1.3	1.4	-1.1	-0.3	1.3
Alcohol intake versus 10 years previously	1.1	1.7	3.2	-1.2	-0.8	-1.2	-1.2	-1.8	1.0	1.8	-1.1
Father’s age at death	0.3	0.5	1.7	-0.5	-0.6	-0.1	-0.0	1.1	0.3	-1.3	-0.2
Worrier / anxious feelings	0.9	1.6	5.0	0.6	0.2	0.9	0.9	1.8	-1.3	-2.2	1.1
Frequency of tiredness / lethargy in last 2 weeks	2.5	4.1	5.9	2.2	2.4	2.3	2.3	1.0	-2.3	-0.4	2.3
Falls in the last year	0.3	0.4	0.6	-0.7	-0.8	-0.6	-0.7	0.2	0.6	-0.5	-0.6
Hair/balding pattern: Pattern 3	1.1	1.6	5.8	-1.1	-0.3	-1.0	-0.9	-2.4	0.4	1.8	-0.9
Number of live births	2.2	3.1	4.3	2.0	1.5	1.9	2.1	1.8	-1.6	-1.3	1.8
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.1	-1.0	-0.9	-0.5	-0.2	0.9	0.5	-0.1	-0.5
Pulse rate	0.8	1.4	2.1	1.2	1.4	1.2	1.1	-0.9	-1.5	-0.6	1.3
Happiness	0.4	0.5	0.9	-1.0	-0.9	-0.8	-0.7	0.2	0.6	-0.1	-0.7
Noisy workplace	1.4	1.7	3.2	-0.9	-1.3	-1.3	-1.3	0.2	1.8	1.5	-1.5
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.6	0.5	0.8	1.2	1.2	0.3	-1.2	-0.8	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.7	0.3	0.5	0.4	0.3	0.9	0.2	0.1	0.3
Mouth/teeth dental problems: Dentures	0.1	0.2	0.7	-0.2	-0.2	-0.1	-0.3	-0.8	0.1	-0.7	-0.1
Asthma	0.6	1.1	3.2	1.2	1.8	0.9	0.8	-0.4	-0.9	0.8	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	1.0	0.1	-0.1	0.2	0.1	1.0	0.1	-0.8	0.1
Medication: Cholesterol lowering	1.8	2.8	6.4	-1.7	-1.6	-1.7	-1.9	-2.5	1.1	-0.1	-1.6
Depression (self-reported)	2.3	2.7	4.9	1.4	2.1	1.7	1.8	-0.6	-2.2	-0.6	1.8
Medication: Lansoprazole	0.5	0.5	1.4	-0.7	-1.2	-0.8	-0.8	0.0	0.5	-0.7	-0.7
Prospective memory result	0.3	0.3	0.5	0.7	0.7	0.5	0.5	-0.2	-0.7	0.4	0.6
Lung cancer (father)	0.6	0.7	3.6	0.6	0.6	0.2	-0.0	-1.9	-0.4	1.1	0.3
Illnesses of mother	0.1	0.1	0.8	0.1	0.1	0.0	0.3	0.2	0.1	0.9	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	1.9	0.2	0.3	0.8	1.0	1.4	-0.9	-1.3	0.8
Pulse wave Arterial Stiffness index	1.0	1.1	1.5	0.8	1.1	1.2	1.2	0.5	-1.2	-1.1	1.2
Impedance of arm (left)	1.6	7.5	12.9	3.6	3.3	2.8	3.0	2.7	-2.1	0.7	2.7
Arm fat mass (right)	0.1	0.5	1.0	-0.6	-0.9	-0.7	-0.9	-1.0	0.4	-0.4	-0.7
Trunk predicted mass	2.2	12.4	20.6	-4.5	-4.0	-3.8	-3.8	-3.1	3.1	0.9	-3.7
Standing height	0.5	5.3	10.5	-2.5	-1.9	-2.3	-2.0	-0.9	2.4	3.2	-2.3
Length of working week for main job	0.9	0.9	2.3	-0.6	-0.9	-1.0	-1.2	0.4	1.5	0.3	-1.2
Exposure to tobacco smoke at home	0.1	0.1	0.4	0.2	0.1	-0.1	-0.1	-0.6	-0.1	-0.1	-0.0
Breastfed as a baby	0.6	0.7	1.3	-0.4	-0.7	-0.9	-0.8	-0.3	1.2	0.9	-1.0
Tense / ‘highly strung’	3.4	5.6	7.4	2.3	2.6	2.6	2.7	1.7	-2.7	-1.2	2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.6	-0.2	0.1	0.3	0.4	0.7	-0.6	-1.2	0.4
Hair/balding pattern: Pattern 4	0.9	2.2	3.2	-1.5	-1.8	-1.7	-1.7	0.4	1.8	-0.6	-1.7
Birth weight of first child	0.4	0.7	1.0	-0.5	-0.7	-1.0	-0.9	-0.8	0.8	0.8	-0.9
Peak expiratory flow (PEF)	0.2	0.4	1.2	-0.9	-1.1	-0.6	-0.4	0.3	0.3	-0.0	-0.5
Pulse wave reflection index	0.7	0.9	3.1	0.3	0.3	0.8	0.7	1.3	-0.7	-1.8	0.7
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.1	0.2	0.4	0.2	0.2	0.2	-0.3	-0.2	0.2
Loud music exposure frequency	1.8	2.0	3.2	1.3	1.4	1.4	1.6	0.5	-1.8	-1.5	1.6
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.2	0.1	0.4	0.7	0.7	-0.1	-0.9	-1.1	0.8
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.5	0.9	1.1	0.8	0.6	1.1	-0.2	1.6	0.7
Blood clot in the leg (DVT)	2.1	2.7	3.8	1.9	1.4	1.8	1.9	2.0	-1.4	-0.7	1.8
Medication: Paracetamol	1.1	1.8	4.1	0.8	0.9	1.2	1.3	1.0	-1.7	-2.0	1.3
Headache pain in last month	0.5	0.9	1.8	0.7	0.6	1.0	0.9	1.1	-0.9	-1.4	1.0
Medication for cholesterol, blood pressure or diabetes	3.3	5.5	7.6	2.5	2.6	2.6	2.8	2.5	-2.1	-0.1	2.5
Glaucoma (self-reported)	0.3	0.4	1.0	0.8	0.8	0.6	0.6	-0.2	-0.2	1.0	0.5
Gout (self-reported)	0.5	0.7	1.3	-0.9	-1.1	-1.0	-0.9	-0.2	0.8	-0.6	-0.9
Hypothyroidism/myxoedema (self-reported)	1.8	3.6	4.4	1.8	1.9	2.0	2.1	1.7	-2.0	-1.6	2.0
Medication: Amlodipine	0.7	1.0	2.3	-0.7	-1.5	-0.8	-1.0	0.2	0.8	-1.5	-0.8
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.5	1.2	1.1	0.8	0.8	-0.5	-1.2	-0.2	0.9
Birth weight	0.4	1.0	1.5	0.5	0.5	1.0	1.1	1.2	-1.1	-1.1	1.0
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.4	0.1	0.6	0.6	0.6	0.6	-0.6	-0.7	0.6
High blood pressure (siblings)	2.6	3.8	7.3	-1.9	-2.0	-2.0	-2.3	-2.7	1.3	-0.4	-1.9
Forced vital capacity (FVC), Best measure	0.4	1.6	4.4	0.6	0.7	1.2	1.5	2.1	-1.2	-1.3	1.2
Body fat percentage	0.1	0.6	1.8	1.3	0.9	0.7	0.5	0.0	-0.7	0.3	0.7
Leg fat percentage (right)	0.1	0.4	0.7	0.8	0.6	0.5	0.3	-0.7	-0.8	-0.4	0.6
Arm fat-free mass (right)	1.5	7.5	11.2	-3.3	-3.0	-2.9	-3.0	-2.7	2.4	1.2	-2.8
Exposure to tobacco smoke outside home	0.5	0.7	4.0	0.7	0.5	-0.1	-0.1	0.3	0.6	2.0	-0.2
Comparative body size at age 10	0.5	1.4	8.6	-0.2	-0.0	0.5	0.4	0.4	-1.2	-2.9	0.7
Number of full brothers	0.7	0.9	1.4	1.2	0.8	1.0	1.1	0.6	-1.0	-0.5	1.0
Worry too long after embarrassment	0.1	0.1	0.5	-0.7	-0.2	-0.2	-0.2	-0.5	-0.1	-0.1	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.1	0.2	0.3	0.2	0.1	-0.1	0.3	0.1	0.5	-0.0
Wheeze or whistling in the chest in last year	0.5	0.9	1.9	0.7	1.3	0.5	0.4	-1.2	-0.7	1.4	0.5
Number of children fathered	0.0	0.0	0.2	0.1	0.1	0.0	-0.1	0.1	0.1	0.4	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	4.6	5.3	9.6	-2.9	-3.1	-2.5	-2.5	-0.2	2.3	-0.7	-2.5
Age at first live birth	0.1	0.3	1.7	-0.1	0.5	0.2	0.2	-0.0	0.1	1.3	0.1
Pulse wave peak to peak time	1.1	1.2	1.7	-0.9	-1.1	-1.3	-1.2	-0.7	1.1	1.2	-1.2
Health satisfaction	0.2	0.2	1.2	-0.3	-0.5	-0.2	-0.3	-0.1	0.1	-1.1	-0.2
Shortness of breath walking on level ground	1.7	2.0	2.9	-1.6	-1.7	-1.6	-1.7	-1.4	1.0	-0.5	-1.4
Qualifications: College or University degree	0.6	1.9	6.6	-0.1	0.6	1.2	1.3	0.8	-1.5	-2.6	1.3
Eye problems/disorders: None of the above	0.6	0.7	0.9	0.9	0.9	0.9	0.9	0.4	-0.9	-0.4	0.9
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.5	1.6	1.6	1.3	1.2	-0.4	-1.4	-0.4	1.4
Emphysema/chronic bronchitis	0.7	0.8	3.4	-0.2	-0.0	-0.5	-0.5	-1.2	0.5	1.8	-0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	3.2	0.4	0.8	0.1	-0.0	-1.6	0.1	1.8	-0.0
Neck or shoulder pain in last month	0.8	1.1	2.0	-1.0	-1.1	-1.0	-1.2	-0.1	1.4	1.0	-1.2
Medication: Blood pressure	3.4	6.0	10.0	-2.6	-3.2	-2.7	-2.8	-1.6	2.5	0.0	-2.7
Angina (self-reported)	0.8	1.1	1.4	-0.7	-1.1	-1.1	-1.2	-0.9	1.2	0.8	-1.2
Migraine (self-reported)	0.0	0.0	0.1	-0.3	0.1	-0.1	0.0	0.3	0.1	0.1	-0.1
Medication: Ibuprofen	0.4	0.5	1.3	0.4	0.4	0.6	0.7	0.6	-0.6	-1.2	0.6
Medication: Allopurinol	0.4	0.5	3.6	-0.1	-0.3	0.0	0.1	0.7	-0.3	-1.9	0.1
Medication: Omeprazole	1.5	1.8	6.1	0.8	0.6	1.0	1.3	2.5	-1.0	-1.7	1.1
Medication: Seretide 50 evohaler	0.6	0.6	1.3	-0.1	-0.8	-0.6	-0.8	1.1	1.2	0.7	-0.8
Mean time to correctly identify matches	1.5	2.8	4.2	-2.1	-2.0	-1.9	-1.9	-0.5	1.8	0.0	-1.9
Heart disease (mother)	0.3	0.4	1.1	-0.4	-0.4	-0.5	-0.8	-1.0	0.4	0.5	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.5	1.0	1.1	0.9	1.0	1.6	-0.5	-0.1	0.8
Whole body fat mass	0.1	0.5	1.1	-0.3	-0.5	-0.7	-0.9	-1.1	0.5	0.9	-0.6
Leg fat mass (right)	0.1	0.4	1.7	-0.3	-0.5	-0.6	-0.8	-1.3	0.2	0.2	-0.5
Arm predicted mass (right)	1.5	7.5	10.9	-3.3	-3.0	-3.0	-3.0	-2.4	2.5	1.3	-2.9
Pulse rate, automated reading	0.6	1.9	3.1	1.6	1.1	1.3	1.1	-0.5	-1.6	-1.8	1.4
Alcohol intake frequency.	1.6	3.7	4.6	-1.8	-1.8	-2.0	-2.1	-1.3	2.2	1.9	-2.1
Comparative height size at age 10	2.6	14.1	25.6	-5.1	-4.7	-4.1	-4.0	-0.9	3.8	-0.1	-4.0
Number of full sisters	0.5	0.7	1.2	0.8	1.0	0.9	0.8	-0.2	-1.1	-0.0	1.0
Suffer from ‘nerves’	0.9	1.4	2.1	1.3	1.5	1.2	1.3	1.0	-1.2	-0.6	1.3
Overall health rating	0.3	0.7	1.7	-0.4	-0.3	-0.9	-0.9	-1.1	0.7	1.3	-0.9
Chest pain or discomfort	2.6	3.8	5.5	-2.3	-1.8	-2.1	-2.2	-0.8	2.1	1.6	-2.1
Had major operations	0.9	1.1	5.5	-1.0	-0.9	-0.2	-0.1	1.2	-0.1	-2.3	-0.1
Age at last live birth	0.0	0.1	0.2	-0.4	-0.0	0.0	0.0	0.3	0.3	0.4	-0.1
Family relationship satisfaction	0.8	1.0	4.5	-0.3	-0.8	-0.0	0.0	2.1	-0.0	-1.7	0.0
Leg pain on walking	0.8	0.9	1.3	-1.1	-1.2	-1.0	-1.1	-1.2	0.8	-0.0	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.0	0.9	0.9	0.5	0.4	-1.0	-0.5	0.9	0.5
Commuting to job workplace: Car/motor vehicle	0.8	0.9	1.6	-0.9	-1.2	-1.1	-1.1	0.1	1.1	0.3	-1.2
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	2.6	-1.2	-1.5	-1.6	-1.6	-0.2	1.6	1.0	-1.6
Medication: Aspirin	0.0	0.0	0.1	0.2	-0.2	0.0	-0.3	0.2	0.0	-0.2	-0.0
Supplements: Vitamin C	2.0	2.3	2.9	1.7	1.6	1.6	1.6	1.6	-1.3	-1.1	1.6
Knee pain experienced in last month	0.7	1.0	1.8	-1.3	-1.1	-1.0	-1.1	-1.2	0.7	-0.2	-0.9
Hypertension (Self-reported)	4.2	11.7	16.2	-3.9	-4.0	-3.9	-4.0	-2.5	3.3	0.4	-3.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	4.4	0.9	0.4	1.3	1.3	1.8	-1.3	-2.1	1.3
Illnesses of father: Heart disease	0.3	0.4	0.7	0.4	0.1	0.6	0.6	0.5	-0.8	-0.8	0.7
Illnesses of siblings: Diabetes	0.2	0.3	0.7	0.2	-0.2	-0.4	-0.6	-0.8	0.4	0.7	-0.4
Smoking status: Previous	0.4	0.6	2.4	0.8	0.9	0.3	0.3	-1.5	-0.6	-0.3	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.9	0.2	0.2	0.0	0.1	-0.1	-0.1	0.9	0.0
Whole body fat-free mass	1.6	9.4	15.1	-3.9	-3.5	-3.3	-3.3	-2.9	2.6	0.8	-3.2
Leg fat-free mass (right)	0.9	5.1	7.7	-2.8	-2.5	-2.4	-2.5	-2.4	1.9	0.5	-2.3
Arm fat percentage (left)	0.0	0.1	0.3	0.6	-0.0	0.2	-0.1	-0.3	-0.3	-0.5	0.2
Average weekly red wine intake	0.7	1.0	2.0	-1.4	-1.1	-1.1	-0.9	-1.1	0.8	0.0	-1.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.7	-0.2	-0.6	-0.3	-0.6	1.6	1.0	0.4	-0.5
Mood swings	0.2	0.4	2.4	-0.2	-0.4	0.1	0.1	0.7	-0.4	-1.5	0.2
Loneliness, isolation	1.3	1.8	3.5	1.1	0.7	1.4	1.3	0.9	-1.6	-1.9	1.4
Long-standing illness, disability or infirmity	0.5	0.8	2.2	-0.5	-0.1	-0.8	-0.9	-1.1	0.8	1.5	-0.8
Ever had bowel cancer screening	0.3	0.4	1.0	-1.0	-0.6	-0.7	-0.6	-0.3	0.7	0.3	-0.7
Diabetes diagnosed by doctor	1.3	2.2	3.0	-1.7	-1.6	-1.6	-1.7	-1.5	1.3	-0.6	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	3.0	3.2	5.2	2.3	1.9	2.0	1.9	1.1	-1.8	-1.1	1.9
Friendships satisfaction	0.7	0.9	1.8	-1.2	-1.3	-1.0	-1.1	0.1	0.9	-0.5	-1.0
Qualifications: nursing, teaching	1.5	2.3	4.2	-2.0	-1.4	-1.7	-1.5	-1.2	1.4	1.1	-1.6
Commuting to job workplace: Walk	2.8	3.1	4.7	1.9	2.2	2.0	1.7	0.2	-1.9	-1.3	2.0
Eye problems/disorders: Cataract	2.3	2.7	3.6	-1.8	-1.6	-1.9	-1.8	-1.3	1.7	1.0	-1.9
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.7	-1.2	-0.6	-0.8	-1.0	-1.3	0.8	0.7	-0.8
Medication for cholesterol	0.1	0.2	0.5	0.4	0.7	0.3	0.1	-0.6	-0.1	0.7	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	3.8	-0.1	-0.4	0.2	0.1	1.7	-0.1	-1.9	0.2
Back pain experienced in last month	0.1	0.2	0.3	0.5	0.5	0.5	0.2	0.4	-0.1	0.5	0.4
Mineral and other dietary supplements	0.1	0.2	1.3	-0.2	-0.2	-0.2	-0.3	-1.1	-0.1	-0.1	-0.1
Breast cancer (self-reported)	0.4	0.5	1.8	0.2	0.0	0.6	0.6	0.6	-0.7	-1.3	0.7
Asthma (self-reported)	0.4	0.9	2.5	1.1	1.6	0.9	0.7	-0.3	-0.8	0.7	0.9
Osteoporosis (self-reported)	5.8	7.2	9.6	3.1	2.8	3.0	3.0	2.5	-2.5	-1.2	2.9
Osteoarthritis (self-reported)	0.4	0.5	1.4	-0.8	-0.6	-0.7	-0.8	-1.2	0.2	-0.6	-0.5
Medication: Aspirin	0.1	0.2	0.4	-0.2	-0.5	-0.4	-0.6	-0.2	0.4	0.2	-0.4
Medication: Gliclazide	0.4	0.5	0.7	-0.6	-0.8	-0.8	-0.9	-0.8	0.6	-0.1	-0.7
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	-0.1	-0.4	-0.2	-0.4	-0.0	0.5	0.0	-0.3
Smoking status: Current	0.3	0.4	2.1	0.3	0.3	-0.0	-0.2	0.7	0.6	1.5	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.5	5.2	14.8	1.6	0.8	1.9	1.9	2.9	-2.0	-3.9	2.0
Whole body water mass	1.8	10.0	16.1	-4.0	-3.5	-3.4	-3.5	-3.0	2.7	0.9	-3.3
Leg predicted mass (right)	0.9	4.9	7.5	-2.7	-2.5	-2.4	-2.4	-2.3	1.8	0.4	-2.2
Arm fat mass (left)	0.1	0.6	1.1	-0.6	-1.0	-0.8	-1.0	-1.1	0.5	-0.2	-0.7
Number of self-reported non-cancer illnesses	0.3	0.6	1.2	-1.0	-0.5	-0.7	-0.7	-1.1	0.1	-0.9	-0.5
Average weekly champagne plus white wine intake	0.1	0.1	0.3	-0.5	-0.5	-0.3	-0.3	-0.4	0.0	-0.6	-0.2
Miserableness	0.2	0.4	0.9	-1.0	-0.6	-0.6	-0.8	-0.6	0.5	0.2	-0.6
Guilty feelings	0.2	0.3	1.7	-0.7	-0.5	-0.3	-0.4	-0.1	-0.1	-1.3	-0.2
Wears glasses or contact lenses	3.4	3.9	4.5	-1.9	-2.1	-2.0	-2.0	-1.6	2.0	2.1	-2.0
Ever taken oral contraceptive pill	0.4	0.4	1.7	0.5	0.2	0.6	0.5	1.3	-0.0	0.9	0.4
Hearing aid user	0.6	0.7	1.5	-0.8	-1.2	-0.8	-1.0	-1.1	0.5	-0.5	-0.7
Mother’s age at death	0.9	1.2	1.9	0.8	1.0	1.3	1.4	0.5	-1.2	-0.8	1.3
Financial situation satisfaction	0.3	0.4	1.1	-1.1	-0.5	-0.6	-0.6	-0.5	0.4	-0.7	-0.5
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.2	-1.1	-1.1	-0.9	-0.9	-1.0	0.5	-0.8	-0.8
Commuting to job workplace: Public transport	0.3	0.4	1.5	-0.8	-0.4	-0.5	-0.4	-1.2	0.0	-0.5	-0.4
Eye problems/disorders: Glaucoma	0.9	1.1	3.5	-1.0	-0.6	-0.9	-0.9	-1.9	0.7	1.1	-0.8
Medication: Blood pressure	2.7	5.2	8.0	-2.7	-2.8	-2.6	-2.6	-0.6	2.4	0.2	-2.6
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.8	-0.5	-0.4	-0.7	-0.7	0.5	0.9	0.5	-0.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.9	0.5	0.6	0.5	0.6	1.0	-0.3	-0.3	0.5
High cholesterol (Self-reported)	0.7	1.2	2.6	-1.2	-1.6	-1.2	-1.3	-0.5	0.9	-0.6	-1.1
Medication: Bendroflumethiazide	1.9	2.9	4.8	-2.1	-2.2	-1.8	-1.8	-1.3	1.4	-1.1	-1.7
Medication: Paracetamol	1.1	1.7	4.4	0.7	0.8	1.1	1.3	1.1	-1.5	-2.1	1.2
Medication: Lisinopril	3.1	4.0	7.7	-2.8	-2.4	-2.2	-2.2	-1.8	1.5	-0.3	-2.0
Medication: Atorvastatin	0.6	0.7	1.0	-0.6	-0.6	-1.0	-1.0	-0.9	0.8	0.7	-0.9
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.6	-0.5	-0.4	-0.4	0.1	0.1	-0.2	-0.3
Alcohol drinker status: Never	0.7	0.8	1.5	-1.1	-1.2	-0.8	-1.0	-1.2	0.4	-0.3	-0.7
Ever smoked	0.0	0.1	0.3	0.2	0.5	-0.1	-0.1	-0.2	0.2	0.0	-0.1
Basal metabolic rate	1.3	7.4	11.7	-3.4	-3.1	-2.9	-3.0	-2.6	2.3	0.7	-2.8
Leg fat percentage (left)	0.1	0.5	1.4	1.2	0.7	0.7	0.5	-0.0	-0.8	-0.3	0.7
Arm fat-free mass (left)	1.6	8.4	13.0	-3.6	-3.3	-3.1	-3.2	-2.6	2.6	0.9	-3.0
Number of operations (self-reported)	0.4	0.6	3.3	-0.7	-0.4	-0.1	-0.2	-0.5	-0.6	-1.8	0.1
Average weekly beer plus cider intake	4.1	6.0	12.1	3.5	3.1	2.6	2.5	1.1	-2.1	0.9	2.5
Irritability	0.2	0.4	0.9	-0.7	-0.6	-0.4	-0.5	1.0	0.7	-0.1	-0.5
Risk taking	1.5	2.2	3.8	1.8	2.0	1.5	1.5	1.8	-0.9	0.8	1.3
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.5	0.7	0.8	0.7	0.6	1.2	-0.6	-1.0	0.6
Fractured/broken bones in last 5 years	2.8	3.7	4.9	1.6	1.8	2.0	2.1	1.9	-2.2	-1.3	2.1
Age started oral contraceptive pill	0.2	0.2	0.9	0.5	0.7	0.2	0.3	0.4	0.2	1.0	0.1
Diastolic blood pressure, automated reading	0.9	2.7	5.0	-1.6	-1.6	-1.8	-2.0	-2.2	1.2	0.1	-1.6
Ever depressed for a whole week	0.5	0.6	2.4	0.5	0.4	0.5	0.4	0.8	-0.7	-1.6	0.5
Unable to work because of sickness or disability	0.6	0.7	4.9	0.6	-0.2	0.2	0.3	2.2	-0.0	-0.5	0.1
Commuting to job workplace: Cycle	0.9	1.1	1.6	1.1	1.0	1.1	1.1	1.3	-0.9	-0.2	1.1
Myopia	0.4	0.5	1.7	-1.0	-0.9	-0.5	-0.5	-0.3	0.2	-1.3	-0.4
Vascular/heart problems diagnosed by doctor	3.6	9.8	13.4	3.5	3.6	3.5	3.7	2.6	-3.0	-0.5	3.4
Cholesterol lowering medication	0.3	0.4	2.1	-0.1	-0.4	0.3	0.3	0.6	-0.6	-1.5	0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	4.1	0.1	0.2	0.3	0.6	2.0	-0.3	-0.9	0.3
Pain experienced in last month	0.1	0.1	0.4	-0.5	-0.2	-0.4	-0.0	-0.6	-0.2	-0.1	-0.2
Supplements: Calcium	0.1	0.1	0.4	0.0	-0.2	-0.1	0.0	0.6	0.1	-0.7	-0.1
Basal cell carcinoma (self-reported)	0.9	1.1	1.5	1.2	1.1	1.1	1.2	1.1	-1.0	-0.3	1.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.8	-0.4	-0.5	-0.6	-0.6	-0.6	0.7	0.9	-0.7
Deep venous thrombosis (DVT) (self-reported)	1.8	2.4	3.7	1.7	1.3	1.7	1.8	1.9	-1.2	-0.6	1.6
Heart disease (siblings)	0.6	0.7	2.2	0.4	0.5	0.6	0.6	-1.5	-1.1	-0.7	0.8
Alcohol drinker status: Previous	2.2	2.5	4.2	-1.6	-1.8	-1.8	-1.6	0.6	2.0	0.6	-1.9
Pack years of smoking	0.2	0.2	1.5	0.1	0.2	-0.1	-0.1	-0.4	-0.0	1.2	-0.1
Impedance of whole body	2.5	12.7	21.0	4.6	4.3	3.7	3.9	3.6	-2.7	1.3	3.5
Leg fat mass (left)	0.1	0.3	1.1	-0.2	-0.4	-0.5	-0.7	-1.1	0.2	0.3	-0.4
Arm predicted mass (left)	1.4	7.3	11.5	-3.4	-3.1	-2.9	-2.9	-2.4	2.4	0.8	-2.8