Best TWAS P=9.12e-14 · Best GWAS P=5.35e-12 conditioned to 0.122
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | EXD1 | 0.04 | 0.04 | lasso | 3 | 0.04 | 8.1e-06 | -4.9 | 5.2 | 1.7e-07 | -0.94 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Lung | OIP5-AS1 | 0.09 | 0.08 | enet | 14 | 0.12 | 2.8e-09 | -5.2 | -5.1 | 2.6e-07 | 0.82 | 0.40 | 0.60 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CHP | 0.06 | 0.01 | blup | 54 | 0.03 | 4.7e-04 | -4.2 | 7.5 | 9.1e-14 | -0.80 | 0.03 | 0.74 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LOC729082 | 0.06 | 0.01 | enet | 6 | 0.03 | 3.3e-04 | -4.7 | 6.9 | 5.7e-12 | -0.85 | 0.01 | 0.50 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | INO80 | 0.07 | 0.04 | blup | 40 | 0.06 | 1.2e-03 | -3.8 | -5.4 | 6.2e-08 | 0.79 | 0.04 | 0.54 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CHP | 0.21 | 0.11 | lasso | 4 | 0.12 | 5.1e-13 | -5.2 | 5.9 | 2.8e-09 | -0.65 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | EXD1 | 0.33 | 0.04 | enet | 12 | 0.12 | 6.1e-05 | -6.9 | -6.5 | 8.4e-11 | 0.81 | 0.00 | 0.92 | FALSE |