Best TWAS P=1.97e-23 · Best GWAS P=4e-20 conditioned to 0.189
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RAVER1 | 0.06 | 0.03 | bslmm | 388 | 0.04 | 2.5e-05 | 7.5 | 7.0 | 2.6e-12 | -0.44 | 0.21 | 0.32 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CTD-2623N2.11 | 0.21 | 0.21 | lasso | 2 | 0.20 | 9.0e-26 | -9.2 | -9.2 | 4.0e-20 | 1.00 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | OLFM2 | 0.03 | 0.04 | blup | 47 | 0.04 | 6.7e-09 | -8.0 | 10.0 | 2.0e-23 | -0.85 | 0.10 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PIN1 | 0.04 | 0.06 | blup | 27 | 0.05 | 7.1e-06 | -9.1 | -9.3 | 1.9e-20 | 0.95 | 0.00 | 1.00 | FALSE |