[Hub]/) : Traits : Had menopause : ← →

chr5:175,611,678-177,138,298

Best TWAS P=5.89e-17 · Best GWAS P=1.54e-16 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FGFR4 0.09 0.00 blup 390 0.02 1.9e-03 1.1 -5.2 1.8e-07 0.64 0.04 0.76 FALSE
2 CommonMind Brain Pre-frontal Cortex UIMC1 0.15 0.19 lasso 4 0.19 9.4e-23 -8.2 8.3 1.4e-16 -0.99 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous UIMC1 0.12 0.03 lasso 4 0.02 5.0e-03 -8.2 -7.9 2.3e-15 0.99 0.01 0.97 FALSE
4 GTEx Esophagus Muscularis UIMC1 0.09 0.06 enet 24 0.04 2.3e-03 -8.2 -5.9 4.7e-09 0.81 0.02 0.98 FALSE
5 GTEx Nerve Tibial HK3 0.08 0.00 lasso 5 0.00 4.5e-01 -7.3 -6.8 1.2e-11 0.87 0.06 0.21 FALSE
6 GTEx Skin Sun Exposed Lower leg UIMC1 0.16 0.08 enet 13 0.14 1.5e-11 -8.2 -6.7 3.0e-11 0.83 0.01 0.99 FALSE
7 GTEx Testis UIMC1 0.13 0.18 enet 16 0.16 1.9e-07 -8.2 -8.4 5.9e-17 0.99 0.01 0.99 TRUE
8 GTEx Testis ZNF346 0.19 0.12 enet 18 0.08 1.9e-04 -8.2 7.5 7.7e-14 -0.93 0.01 0.99 FALSE
9 GTEx Thyroid UIMC1 0.10 0.10 lasso 3 0.10 6.0e-08 -8.2 -8.2 2.5e-16 1.00 0.01 0.99 FALSE
10 GTEx Thyroid ZNF346 0.25 0.23 lasso 5 0.22 4.6e-17 -8.2 8.2 1.9e-16 -1.00 0.01 0.99 FALSE
11 METSIM Adipose UIMC1 0.07 0.06 enet 36 0.04 3.6e-07 -7.6 -6.7 1.7e-11 0.90 0.01 0.99 FALSE
12 ROSMAP Brain Pre-frontal Cortex ZNF346 0.06 0.06 enet 17 0.04 2.2e-05 -7.8 6.7 2.0e-11 -0.86 0.02 0.98 FALSE
13 YFS Blood UIMC1 0.03 0.01 enet 28 0.01 1.1e-04 -8.2 -6.3 2.4e-10 0.74 0.01 0.99 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma FGFR4 0.06 0.02 enet 7 0.05 1.2e-06 -7.8 -5.6 2.6e-08 0.77 0.00 0.99 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma ZNF346 0.09 0.05 lasso 3 0.04 3.2e-05 -7.8 7.9 3.7e-15 -0.99 0.01 0.99 FALSE