Best TWAS P=2.22e-08 · Best GWAS P=1.33e-10 conditioned to 0.000737
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HKDC1 | 0.02 | 0.02 | enet | 9 | 0.02 | 3.9e-05 | -5.9 | -5.2 | 1.9e-07 | 0.87 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | HKDC1 | 0.17 | 0.04 | lasso | 5 | 0.07 | 6.0e-04 | -5.2 | -5.1 | 3.1e-07 | 0.67 | 0.08 | 0.45 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | SUPV3L1 | 0.03 | 0.01 | blup | 60 | 0.02 | 6.3e-03 | -4.4 | -5.6 | 2.2e-08 | 0.75 | 0.01 | 0.77 | TRUE |