Best TWAS P=2.99e-11 · Best GWAS P=8.73e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C11orf70 | 0.11 | 0.08 | blup | 438 | 0.10 | 1.3e-12 | 3.1 | -5.4 | 7.5e-08 | -0.48 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Nerve Tibial | YAP1 | 0.09 | 0.07 | lasso | 4 | 0.05 | 1.5e-04 | 6.6 | 6.6 | 3.2e-11 | 0.91 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Nerve Tibial | RP11-864G5.3 | 0.09 | 0.07 | lasso | 4 | 0.05 | 2.2e-04 | 6.6 | 6.5 | 8.6e-11 | 0.93 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Testis | RP11-864G5.3 | 0.15 | 0.18 | lasso | 1 | 0.15 | 2.5e-07 | 6.6 | 6.6 | 3.0e-11 | 0.99 | 0.01 | 0.99 | TRUE |