Best TWAS P=5.69e-08 · Best GWAS P=9.14e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | NT5C2 | 0.06 | 0.04 | lasso | 9 | 0.02 | 1.5e-02 | 5.3 | -5.4 | 5.7e-08 | -0.95 | 0.02 | 0.94 | TRUE |
| 2 | GTEx | Artery Tibial | CYP17A1-AS1 | 0.08 | 0.08 | lasso | 8 | 0.06 | 2.8e-05 | 5.3 | 5.2 | 1.6e-07 | 0.95 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | AS3MT | 0.13 | 0.14 | blup | 62 | 0.13 | 5.6e-06 | 5.3 | -5.1 | 3.0e-07 | -0.92 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | CYP17A1 | 0.04 | 0.02 | lasso | 1 | 0.02 | 3.9e-03 | 5.3 | -5.3 | 9.1e-08 | -1.00 | 0.01 | 0.89 | FALSE |