[Hub]/) : Traits : Birth weight of first child :

chr15:90,718,541-92,135,418

Best TWAS P=2.26e-15 · Best GWAS P=7.67e-13 conditioned to 0.0963

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FURIN 0.12 0.14 lasso 2 0.13 1.2e-15 5.7 -5.7 1.6e-08 0.84 0.95 0.05 FALSE
2 GTEx Adipose Visceral Omentum FES 0.21 0.09 lasso 5 0.05 1.3e-03 -6.1 5.8 5.5e-09 -0.69 0.39 0.24 FALSE
3 GTEx Artery Tibial FES 0.16 0.04 lasso 5 0.05 4.8e-05 -4.8 5.8 6.5e-09 -0.72 0.20 0.78 FALSE
4 GTEx Cells Transformed fibroblasts FES 0.28 0.17 enet 21 0.20 2.8e-15 -6.1 7.3 3.5e-13 -0.89 0.01 0.99 FALSE
5 GTEx Lung FES 0.24 0.07 lasso 6 0.05 5.1e-05 -4.8 6.2 6.3e-10 -0.79 0.11 0.87 FALSE
6 GTEx Skin Sun Exposed Lower leg FES 0.09 0.04 lasso 5 0.04 1.4e-04 -6.1 5.8 7.9e-09 -0.65 0.10 0.58 FALSE
7 GTEx Thyroid FES 0.33 0.19 lasso 6 0.18 4.3e-14 -5.7 5.6 2.0e-08 -0.70 0.95 0.05 TRUE
8 METSIM Adipose FES 0.08 0.06 lasso 3 0.05 6.8e-08 -5.5 5.7 1.6e-08 -0.64 0.94 0.06 FALSE
9 YFS Blood FES 0.31 0.11 enet 77 0.22 1.2e-68 -6.1 6.8 9.1e-12 -0.68 0.02 0.98 FALSE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma FES 0.06 0.05 blup 46 0.06 1.9e-05 -7.1 7.5 6.6e-14 -0.83 0.00 0.99 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma FES 0.06 0.05 blup 46 0.07 7.4e-14 -6.1 7.9 2.3e-15 -0.89 0.01 0.99 TRUE
12 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FES 0.06 0.02 blup 46 0.02 2.4e-02 -6.1 6.0 1.8e-09 -0.77 0.01 0.81 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma FES 0.08 0.07 blup 46 0.06 3.4e-04 -6.8 6.3 2.4e-10 -0.92 0.01 0.98 FALSE
14 The Cancer Genome Atlas Glioblastoma Multiforme FES 0.12 0.06 enet 6 0.06 5.7e-03 -7.2 6.6 4.3e-11 -0.96 0.00 0.94 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FES 0.06 0.03 blup 46 0.05 5.6e-06 -7.2 7.9 3.6e-15 -0.81 0.01 0.99 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FES 0.10 0.07 enet 5 0.05 2.8e-06 -7.2 7.1 1.0e-12 -0.98 0.00 1.00 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma FES 0.05 0.04 lasso 2 0.04 2.2e-05 -6.1 7.0 1.9e-12 -0.88 0.01 0.99 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FES 0.08 0.07 enet 7 0.08 4.2e-09 -6.1 6.4 1.5e-10 -0.81 0.06 0.94 FALSE
19 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FES 0.13 0.16 lasso 2 0.14 6.1e-10 -6.1 6.0 1.6e-09 -0.71 0.65 0.35 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma FES 0.12 0.09 lasso 5 0.08 4.1e-09 -6.1 6.7 1.9e-11 -0.79 0.14 0.86 FALSE
21 The Cancer Genome Atlas Stomach Adenocarcinoma FES 0.04 0.01 blup 46 0.02 1.7e-02 -7.1 7.3 3.6e-13 -0.78 0.01 0.69 FALSE
22 The Cancer Genome Atlas Testicular Germ Cell Tumors FES 0.32 0.26 lasso 2 0.25 2.0e-09 -6.0 6.0 1.5e-09 -0.72 0.35 0.64 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma FES 0.30 0.30 lasso 7 0.32 1.3e-31 -6.0 6.9 3.8e-12 -0.86 0.80 0.20 FALSE