Best TWAS P=1.45e-08 · Best GWAS P=3.24e-08 conditioned to 0.0373
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MAU2 | 0.09 | 0.08 | blup | 369 | 0.10 | 1.0e-12 | -3.3 | 5.6 | 2.0e-08 | -0.73 | 0.43 | 0.56 | FALSE |
| 2 | GTEx | Brain Hippocampus | DDX49 | 0.23 | -0.01 | lasso | 4 | -0.01 | 6.6e-01 | -5.5 | 5.2 | 2.3e-07 | -0.96 | 0.01 | 0.71 | FALSE |
| 3 | GTEx | Esophagus Mucosa | GATAD2A | 0.11 | 0.02 | lasso | 3 | 0.02 | 2.3e-02 | -5.5 | -5.6 | 2.7e-08 | 0.91 | 0.01 | 0.91 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | SUGP1 | 0.03 | 0.00 | blup | 364 | 0.01 | 4.3e-02 | -5.5 | -5.7 | 1.5e-08 | 0.72 | 0.01 | 0.90 | TRUE |