Hub : Genes

GATAD2A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1290 0.0260 0.0e+00 0.297 0.271 0.274 0.283 0.288 1.6e-36 5.3e-33 2.6e-33 1.4e-34 2.4e-35
2 GTEx Cells Transformed fibroblasts 0.0660 0.0300 3.7e-03 -0.003 NA -0.004 NA -0.004 6.3e-01 NA 9.1e-01 NA 8.1e-01
3 GTEx Esophagus Mucosa 0.1070 0.0560 8.2e-03 0.024 NA 0.007 NA 0.017 9.9e-03 NA 1.1e-01 NA 2.3e-02
4 GTEx Whole Blood 0.0640 0.0250 9.0e-05 0.016 NA 0.014 NA 0.026 1.2e-02 NA 1.6e-02 NA 1.7e-03
5 NTR Blood 0.0224 0.0083 3.1e-06 0.018 0.021 0.010 0.021 0.015 9.1e-07 1.4e-07 1.7e-04 2.1e-07 6.6e-06
6 YFS Blood 0.0918 0.0187 0.0e+00 0.139 0.141 0.135 0.137 0.138 5.4e-43 7.5e-44 6.9e-42 1.7e-42 8.9e-43
7 TCGA Colon Adenocarcinoma 0.0390 0.0260 2.8e-03 0.025 0.045 0.037 NA 0.030 1.3e-02 1.2e-03 3.1e-03 NA 7.7e-03
8 TCGA Head and Neck Squamous Cell Carcinoma 0.0179 0.0133 8.5e-03 0.023 0.018 0.014 NA 0.020 1.0e-03 3.5e-03 8.3e-03 NA 2.1e-03
9 TCGA Prostate Adenocarcinoma 0.0377 0.0257 5.2e-04 0.029 0.030 0.021 NA 0.031 4.3e-04 3.9e-04 2.8e-03 NA 2.9e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 2.8 4.5 14.0 -2.6 0.1 -2.4 0.8 2.1 2.0 3.7 2.2 0.6
Bipolar Disorder or Schizophrenia 7.6 18.6 32.9 -5.2 2.9 1.0 3.4 4.5 4.9 5.7 5.1 4.0
Depressed Affect (Nagel 2018) 2.2 4.7 13.8 -1.4 1.1 3.7 2.2 2.3 2.2 0.5 1.6 2.7
Depression (Nagel 2018) 0.4 0.7 3.5 0.5 -0.3 1.9 -0.0 -0.6 0.1 -1.2 -0.2 0.5
Intelligence (Savage-Jansen 2018) 1.1 3.3 9.2 1.4 -3.0 -1.7 -2.0 -1.3 -2.1 -0.8 -1.5 -1.7
Neuroticism (Nagel 2018) 4.7 11.0 14.9 -3.2 2.6 3.3 3.1 3.5 3.9 2.7 3.5 3.9
Schizophrenia (2018) 8.6 17.9 23.3 -4.6 3.6 3.2 3.7 4.0 4.7 4.3 4.8 4.7
Schizophrenia vs Biploar Disorder 2.1 2.8 7.9 -1.2 1.4 2.8 1.1 1.5 1.5 0.8 1.6 2.2
Worry (Nagel 2018) 3.8 8.1 13.0 -3.2 2.0 0.9 2.1 3.6 3.6 3.4 3.1 2.6
Alzheimer’s Disease (in mother) 0.5 0.6 1.1 -0.6 0.9 1.1 0.6 0.9 0.9 0.7 0.6 0.6
Alzheimer’s Disease (in father) 0.2 0.2 0.7 0.1 -0.2 0.8 0.2 0.7 0.1 -0.5 -0.1 0.2
Alzheimer’s Disease (including proxy) 0.8 1.1 2.9 -0.9 0.6 1.7 1.0 1.1 1.1 0.6 1.0 1.2
Crohns Disease (2017) 2.0 4.3 6.8 -2.3 2.6 1.6 2.0 1.9 1.7 2.1 2.3 2.1
Irritable Bowel Disease (IBD) 2.8 6.7 9.2 -2.9 2.6 1.2 2.5 3.0 2.5 2.8 2.9 2.5
Ulcerative Colitis (UC) 2.5 4.7 7.0 -2.5 1.4 0.0 2.1 2.6 2.3 2.6 2.5 1.9
Major Depression (MDD) 0.6 0.7 2.2 0.8 -1.5 0.0 -1.0 -0.7 -0.7 -0.9 -0.6 -0.7
Reaction Time 0.7 1.3 2.6 1.2 -1.2 1.2 -1.4 -1.6 0.2 -1.4 -0.9 0.1
Verbal and Numeric Reasoning (VNR) 1.1 2.5 5.0 1.5 -2.2 -1.4 -1.5 -1.4 -2.0 -1.2 -1.6 -1.3
Breast Cancer 14.8 35.6 46.4 6.6 -5.2 -3.6 -5.9 -5.7 -6.8 -6.2 -6.7 -6.3
Ovarian Cancer 4.0 5.3 7.1 2.7 -2.5 -0.7 -2.4 -1.8 -2.4 -2.6 -2.6 -2.3
Prostate Cancer 3.4 4.7 11.4 -3.4 1.9 1.4 2.5 3.3 3.0 0.0 0.0 0.0
Age at First Birth 1.7 2.4 10.9 0.7 -1.4 -3.3 -1.0 -1.1 -1.1 0.3 -1.0 -1.9
Bipolar Disorder (2011) 1.1 1.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.7 0.8
Body Mass Index (BMI) (2010) 3.5 4.9 7.0 2.7 -2.4 -0.7 -2.6 -1.6 -2.1 -2.5 -2.4 -2.2
Coronary Artery Disease (CAD) 2.5 3.0 8.8 1.6 -3.0 0.0 -2.3 -0.8 -1.5 -1.1 -1.7 -1.9
Crohns Disease (2012) 0.8 1.3 2.0 -1.1 0.7 1.4 1.2 1.1 1.1 0.9 1.1 1.3
Mean Putamen Volume 1.0 1.2 2.1 -1.2 1.1 -0.8 1.4 0.7 1.0 1.4 1.1 0.6
Fasting Glucose 4.0 4.8 7.6 -2.0 2.5 2.7 1.9 1.6 2.6 1.4 2.1 2.5
HbA1C 0.3 0.4 1.5 0.5 0.2 1.2 -0.3 -0.2 -0.0 -1.1 -0.4 0.2
HDL Cholesterol 0.2 0.3 1.2 -0.1 -0.2 -0.3 0.9 -1.1 0.2 0.1 0.1 0.1
LDL Cholesterol 11.6 18.3 46.5 3.2 -6.8 -4.8 -6.0 -2.1 -3.4 -1.9 -3.5 -4.2
Lupus 0.3 0.5 1.4 -0.7 0.4 -1.1 -0.4 0.7 0.1 1.2 0.4 -0.6
Neuroticism (2016) 1.2 1.7 4.0 -0.7 1.4 2.0 1.7 1.1 1.3 0.5 0.9 1.5
Primary Biliary Cirrhosis 0.1 0.1 0.4 0.0 0.6 0.2 0.4 -0.1 0.1 -0.3 -0.1 0.2
Rheumatoid Arthritis 7.1 9.8 16.8 -3.7 2.8 0.9 2.7 4.0 3.3 4.1 3.2 2.3
Schizophrenia (2014) 11.5 25.3 32.7 -5.5 4.1 3.7 4.3 5.0 5.7 5.3 5.7 5.5
Triglycerides 20.3 33.3 72.2 5.0 -8.5 -5.8 -7.5 -3.9 -5.0 -3.4 -5.1 -5.9
Type 2 Diabetes (T2D) (2012) 3.8 4.4 7.8 -1.8 2.8 1.9 2.0 2.0 1.9 1.7 2.1 2.4
Ulcerative Colitis 0.9 1.3 2.5 -1.0 0.7 1.2 1.0 1.6 1.3 0.7 1.2 1.4
Blood Eosinophil Count 5.1 39.3 50.8 -7.1 5.8 2.6 5.7 6.3 7.0 7.0 7.1 6.4
Blood Platelet Count 13.2 152.9 190.4 -13.4 12.7 6.8 12.3 11.7 13.8 13.1 13.5 12.5
Blood Red Count 0.4 3.7 9.7 2.0 2.7 1.7 1.1 -1.6 -1.7 -3.1 -1.7 -0.1
Blood White Count 1.4 10.1 17.0 -3.2 4.1 1.1 3.4 3.4 3.1 3.4 3.1 2.9
Heel T-Score 1.9 15.1 23.8 -3.0 4.6 4.9 4.8 3.3 3.4 2.0 3.2 4.8
BMI 1.5 8.4 21.2 3.4 -2.8 3.8 -2.6 -1.2 -2.5 -4.6 -2.5 -0.1
Height 1.5 28.3 161.3 -2.2 -4.8 -12.7 -2.3 -0.5 -0.8 5.8 0.4 -4.9
Waist Hip Ratio (WHR) 0.5 2.4 5.1 1.6 2.0 2.0 1.0 -1.6 -0.5 -2.2 -1.4 -0.2
Systolic Blood Pressure 0.9 4.4 9.4 -2.2 3.1 -0.6 2.5 2.1 1.4 2.9 1.7 0.8
Smoking Status 1.4 3.5 8.7 -1.5 1.7 3.0 1.2 2.2 1.6 0.9 1.8 2.1
Allergy or Eczema 0.6 1.6 8.3 -0.1 -1.1 -2.9 -1.4 -0.5 -0.3 1.1 -0.0 -1.1
Cardiovascular Disease 0.8 2.8 6.7 2.2 -0.8 0.6 -1.1 -1.2 -1.9 -2.6 -2.1 -1.3
Hypothyroidism (self reported) 2.3 5.2 8.4 -2.7 0.6 1.6 1.8 2.9 1.9 2.8 2.7 2.4
Respiratory disease 0.1 0.3 1.1 0.7 -1.0 0.1 -0.7 -0.4 0.3 -0.5 -0.6 -0.1
Type 2 Diabetes (T2D) (2018) 4.5 8.4 17.9 -1.9 3.9 4.2 3.4 2.1 2.6 0.8 2.0 3.3
Lung FEV1/FVC ratio 0.5 2.6 11.8 -0.2 1.7 3.4 1.4 -0.8 0.2 -1.2 0.8 2.0
Lung FVC 0.0 0.1 0.6 -0.1 -0.1 -0.1 0.1 0.8 0.4 0.2 0.2 0.2
Neuroticism 1.7 4.1 7.8 -1.9 1.0 1.8 2.2 1.9 2.8 1.7 2.1 2.3
Chronotype (morning person) 0.7 1.6 5.1 0.8 -0.6 -2.3 -1.0 -1.2 -1.2 -0.4 -1.1 -1.8
Hair Pigment 0.0 0.8 3.8 0.7 1.0 1.9 0.4 -0.3 -0.3 -1.1 -0.5 0.6
Tanning 0.0 0.2 0.8 0.4 -0.5 0.9 -0.4 0.2 -0.2 -0.7 -0.3 0.1
Hand grip strength (left) 0.4 1.2 2.9 0.1 -1.3 -1.7 -0.7 -1.3 -1.6 0.3 -0.2 -1.0
Number of treatments/medications taken 1.7 3.1 13.5 -0.7 1.1 3.7 1.2 1.0 1.8 -0.3 0.9 2.3
Average weekly spirits intake 1.5 1.9 6.6 -0.8 0.6 2.6 0.8 0.4 1.3 0.2 1.2 2.3
Sensitivity / hurt feelings 11.4 19.5 28.7 -4.7 4.0 3.5 4.0 4.0 5.4 4.1 4.9 4.9
Frequency of depressed mood in last 2 weeks 2.2 3.0 6.4 2.0 -1.6 0.5 -1.0 -2.5 -1.5 -2.4 -1.9 -1.1
Hearing difficulty/problems: Yes 5.7 8.7 17.9 3.7 -2.1 -0.3 -3.0 -2.4 -3.1 -4.2 -3.5 -2.4
Relative age of first facial hair 0.3 0.7 2.1 -0.7 1.1 1.4 0.6 0.7 0.1 -0.0 0.7 0.9
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 1.1 0.8 -1.0 -0.7 -0.9 -1.0 -0.2 -0.8 -0.8 -0.8
Ever used hormone-replacement therapy (HRT) 0.6 0.8 2.8 -0.2 1.7 1.2 1.3 -0.4 0.5 -0.5 0.2 0.8
Ever had hysterectomy (womb removed) 0.2 0.2 0.5 -0.3 -0.5 -0.1 -0.7 0.7 0.5 0.6 0.3 0.3
Systolic blood pressure, automated reading 0.3 1.0 2.5 -1.0 1.5 -0.7 1.1 1.0 0.0 1.6 0.6 0.1
Eye problems/disorders: Diabetes related eye disease 1.8 2.0 6.9 -0.7 2.0 2.6 1.7 0.4 0.3 -0.2 0.9 1.7
Angina 2.4 3.2 5.5 2.2 -2.3 0.0 -1.7 -1.5 -1.1 -2.1 -2.2 -1.5
Medication for hormone replacement therapy 0.5 0.5 1.9 -0.3 0.8 1.4 0.9 -0.1 0.5 -0.2 0.3 0.9
Vitamin and mineral supplements 3.9 5.2 6.7 2.3 -2.4 -2.3 -2.2 -2.1 -2.6 -1.9 -2.4 -2.5
Supplements: Zinc 0.1 0.1 0.3 0.2 -0.5 -0.4 -0.1 -0.5 -0.1 -0.1 -0.2 -0.3
Medication: Co-codamol 3.8 4.4 8.2 -1.9 1.4 2.9 1.4 2.6 2.0 1.6 2.1 2.5
Medication: Metformin 3.0 4.2 9.6 -1.3 2.4 3.1 2.4 1.5 2.2 0.6 1.3 2.5
Diabetes (father) 0.8 1.0 1.8 -1.0 1.3 0.4 1.0 0.7 1.2 1.0 1.0 1.0
Diabetes (mother) 6.6 8.5 14.4 -2.8 3.5 2.5 3.8 2.8 2.7 2.0 2.7 3.0
Severe depression (siblings) 1.5 1.7 2.8 -1.7 0.8 0.6 0.9 1.0 1.5 1.6 1.6 1.5
Pack years adult smoking proportion 1.4 2.1 4.2 -1.4 2.0 0.7 0.8 1.2 2.0 1.2 1.5 1.8
Impedance of leg (right) 8.5 40.9 53.8 -7.3 6.9 2.7 6.2 5.5 7.0 7.2 7.1 6.4
Leg fat-free mass (left) 4.2 22.3 38.8 4.3 -6.2 -4.4 -5.5 -3.4 -4.8 -3.3 -4.5 -5.2
Trunk fat percentage 0.2 0.7 1.9 -0.1 -1.4 1.2 -0.7 1.3 0.5 0.1 0.3 0.8
Hand grip strength (right) 0.5 1.3 3.3 0.5 -1.1 -1.1 -0.9 -1.4 -1.8 -0.4 -0.5 -1.3
Townsend deprivation index at recruitment 5.0 7.0 14.7 3.4 -1.7 -0.1 -2.9 -2.5 -2.1 -3.8 -3.1 -2.3
Current tobacco smoking 3.2 5.2 8.7 -1.9 2.2 2.8 1.8 3.0 2.5 1.5 2.1 2.4
Average weekly fortified wine intake 0.2 0.2 0.9 0.6 0.6 0.1 0.1 -0.3 -0.1 -1.0 -0.5 -0.3
Maternal smoking around birth 8.2 11.9 21.3 -3.0 3.3 4.6 3.2 3.8 2.7 2.2 3.4 4.1
Fed-up feelings 2.0 3.6 10.5 -1.3 1.2 3.2 1.6 1.7 1.9 0.6 1.6 2.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 2.0 -0.2 0.8 1.4 0.6 0.0 0.4 -0.5 0.5 0.8
Relative age voice broke 0.4 0.7 1.7 -1.1 0.9 0.2 0.2 1.3 0.5 1.0 1.0 0.4
Taking other prescription medications 7.0 10.8 18.3 -2.9 2.2 4.2 3.0 2.6 4.2 2.0 3.1 4.3
Age when periods started (menarche) 2.0 4.7 8.4 -2.9 1.4 0.3 1.7 2.2 2.5 2.8 2.6 1.9
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 3.2 0.1 -0.2 1.8 0.2 0.5 0.2 -0.3 0.0 0.8
Heel bone mineral density (BMD) T-score, automated (left) 1.2 2.7 4.7 -1.4 2.0 1.7 2.0 1.3 1.5 0.8 1.6 2.2
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.4 -0.4 0.6 0.3 0.5 0.2 0.3 0.5 0.4 0.3
Qualifications: CSEs or equivalent 0.7 0.9 4.0 -0.3 0.7 2.0 0.6 1.4 0.5 -0.1 0.5 0.7
Serious illness, injury or assault to yourself 0.2 0.3 1.0 0.2 -0.8 0.5 -0.6 0.0 1.0 -0.4 -0.2 0.2
High blood pressure 0.2 0.7 1.9 0.5 1.2 1.0 1.4 0.1 -0.4 -0.9 -0.6 0.2
Hayfever, allergic rhinitis or eczema 1.1 2.3 9.4 0.4 -1.5 -3.1 -1.8 -1.2 -1.0 0.4 -0.7 -1.6
Multivitamins +/- minerals 1.1 1.5 2.2 -1.2 1.5 1.1 1.5 1.2 1.1 0.9 1.2 1.1
Stomach or abdominal pain in last month 5.1 6.3 10.3 -2.4 2.0 3.2 1.7 2.7 2.6 1.8 2.7 3.1
Supplements: Glucosamine 1.2 1.5 5.5 0.6 -1.3 -2.3 -0.9 -1.1 -0.7 0.0 -0.9 -1.6
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 2.9 0.8 -1.7 0.2 -0.5 -0.6 -0.1 -1.0 -0.5 -0.4
Medication: Atenolol 0.0 0.0 0.1 0.2 -0.1 -0.3 -0.1 0.1 0.1 -0.3 -0.3 -0.2
Medication: Levothyroxine sodium 4.8 8.0 13.1 -3.2 2.1 1.7 2.4 3.6 2.6 3.3 3.2 3.0
Sitting height 1.1 7.7 32.2 -2.5 -1.8 -5.7 -0.8 1.6 0.2 4.4 1.7 -1.5
Chronic bronchitis/emphysema (father) 0.4 0.5 1.1 0.7 -0.6 0.1 -0.4 -0.7 -0.9 -1.0 -0.7 -0.4
High blood pressure (mother) 1.3 1.9 4.1 -1.6 1.3 -0.3 1.6 1.8 0.5 2.0 1.2 0.7
Body mass index (BMI) 1.1 4.6 14.1 2.3 -1.4 3.8 -1.5 -0.5 -1.5 -3.5 -1.6 0.5
Impedance of leg (left) 8.9 43.0 55.5 -7.5 7.0 3.3 6.5 5.9 7.0 7.1 7.2 6.6
Leg predicted mass (left) 4.2 22.4 38.8 4.3 -6.2 -4.5 -5.5 -3.5 -4.8 -3.3 -4.5 -5.2
Trunk fat mass 0.3 1.3 6.1 0.8 -2.5 0.0 -1.8 0.3 -0.6 -0.7 -0.6 -0.4
Waist circumference 1.2 4.3 11.6 2.8 -1.7 1.8 -1.8 -1.3 -1.7 -3.4 -2.3 -0.8
Number of incorrect matches in round 0.2 0.3 0.9 -0.2 0.7 1.0 0.5 0.3 0.4 -0.2 0.4 0.9
Past tobacco smoking 0.0 0.0 0.2 0.0 0.0 -0.4 -0.2 -0.0 0.2 0.2 -0.2 -0.3
Alcohol usually taken with meals 0.5 0.8 2.2 -0.8 1.5 -1.1 1.0 0.0 0.0 1.3 0.6 0.0
Nervous feelings 1.7 3.1 6.8 -2.1 0.8 -0.1 0.9 1.9 2.6 2.5 1.9 1.3
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.3 2.4 1.2 -1.2 0.2 -1.5 -1.2 -0.7 -1.5 -1.0 -0.9
Hearing difficulty/problems with background noise 0.3 0.4 1.5 1.0 0.6 0.2 -0.4 0.0 -0.5 -1.2 -0.8 -0.1
Hair/balding pattern: Pattern 2 3.8 4.8 8.1 -1.9 1.8 2.7 2.1 1.8 2.6 1.1 2.2 2.9
Had menopause 0.6 0.7 1.4 0.9 1.1 0.6 0.7 -1.1 -0.3 -1.2 -1.0 -0.0
Had other major operations 0.1 0.1 0.5 -0.2 -0.3 -0.7 -0.1 0.3 0.4 0.1 0.0 0.0
Forced vital capacity (FVC) 1.0 4.0 15.1 0.5 -2.7 -3.9 -2.0 -0.8 -1.2 0.6 -0.8 -2.4
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.7 3.9 -0.8 1.4 2.0 1.8 0.9 0.6 0.4 1.1 1.7
Ever unenthusiastic/disinterested for a whole week 1.1 1.4 3.6 1.6 -1.0 -0.2 -0.8 -0.1 -1.0 -1.9 -1.5 -1.1
Qualifications: None of the above 5.4 11.5 17.4 -2.7 4.0 4.2 3.0 4.1 3.0 1.8 3.1 3.9
Financial difficulties in last 2 years 0.9 1.3 3.6 1.3 -0.6 1.7 -1.0 -0.1 -0.6 -1.9 -1.1 -0.4
Mouth/teeth dental problems 1.1 1.7 7.6 0.2 -0.6 -2.8 0.1 -0.6 -0.7 0.8 -0.8 -2.2
Heart attack 0.2 0.3 0.7 -0.6 -0.2 -0.5 -0.1 0.4 0.8 0.8 0.6 0.5
Allergy 1.0 2.4 7.0 -0.7 2.1 2.6 2.2 1.0 0.7 -0.1 1.0 1.6
Pain all over the body in last month 1.8 1.9 7.7 -0.4 1.0 2.8 0.7 2.1 0.8 -0.4 0.6 1.4
Diabetes (self-reported) 2.2 3.4 8.0 -1.0 2.8 2.6 2.8 0.4 1.4 0.4 0.9 1.9
Hayfever/allergic rhinitis (self-reported) 1.4 1.9 5.0 0.7 -2.2 -1.6 -1.9 -0.9 -1.2 -0.2 -1.1 -1.4
Medication: Ramipril 3.5 4.5 6.9 -1.9 2.6 1.8 2.6 2.3 2.0 1.7 1.9 2.1
Medication: Simvastatin 9.7 14.3 20.3 4.0 -4.5 -3.0 -3.7 -3.2 -3.6 -3.4 -4.0 -4.2
Fluid intelligence score 3.0 6.2 9.5 2.4 -3.1 -2.6 -2.6 -2.2 -2.7 -1.9 -2.4 -2.5
Illnesses of siblings 1.7 2.3 3.8 1.2 -1.8 -1.7 -1.9 -1.5 -1.7 -0.7 -1.1 -1.7
Neuroticism score 0.6 1.2 3.0 -0.9 -0.2 1.0 0.8 1.2 1.7 0.8 1.1 1.3
Weight 1.2 5.9 13.8 2.4 -3.7 -1.1 -3.2 -1.4 -2.5 -2.2 -2.3 -2.1
Impedance of arm (right) 1.8 8.3 25.7 -3.1 -0.5 -5.0 0.4 1.7 2.4 5.1 2.2 -0.5
Arm fat percentage (right) 0.4 1.7 3.6 1.3 -1.9 1.8 -1.5 0.1 -0.6 -1.7 -0.9 0.1
Trunk fat-free mass 2.8 16.2 21.4 3.6 -4.6 -4.2 -4.5 -3.2 -4.3 -2.8 -3.8 -4.6
Hip circumference 0.5 2.3 8.2 1.4 -2.9 0.2 -2.3 -0.1 -1.4 -1.4 -1.1 -0.7
Time employed in main current job 1.5 1.7 3.9 -1.1 2.0 1.2 1.2 1.2 1.3 0.7 1.3 1.3
Alcohol intake versus 10 years previously 3.6 5.3 7.7 -2.1 2.0 2.5 2.8 2.6 1.9 1.5 2.4 2.7
Father’s age at death 0.5 0.6 3.3 -0.1 0.2 -1.8 0.0 -0.5 -0.2 1.0 -0.4 -0.9
Worrier / anxious feelings 1.7 3.1 5.1 -1.6 1.4 2.0 1.5 1.6 2.3 1.4 1.8 2.1
Frequency of tiredness / lethargy in last 2 weeks 2.1 3.5 11.0 -1.1 1.7 3.3 1.9 1.1 1.9 0.3 1.4 2.4
Falls in the last year 1.9 2.5 5.8 -1.5 1.5 0.9 1.0 2.4 1.8 1.4 1.5 1.8
Hair/balding pattern: Pattern 3 1.6 2.4 4.2 1.4 -1.6 -1.0 -1.4 -2.1 -1.8 -1.1 -1.5 -1.7
Number of live births 2.8 3.9 9.3 -1.6 2.0 3.0 1.5 2.4 1.5 0.9 1.7 2.4
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 5.0 0.1 -1.8 -2.2 -1.0 -1.0 -0.8 0.4 -0.3 -1.3
Pulse rate 3.3 5.5 8.8 -2.6 2.3 1.6 1.9 2.3 3.0 2.3 2.6 2.3
Happiness 2.6 3.1 6.5 1.8 -2.5 -1.5 -1.6 -1.7 -1.3 -1.4 -1.9 -1.8
Noisy workplace 0.1 0.2 0.5 -0.1 -0.7 -0.6 0.1 0.4 -0.6 0.3 -0.1 -0.3
Qualifications: A levels/AS levels or equivalent 3.3 7.3 14.5 1.7 -3.6 -3.8 -2.4 -3.1 -2.3 -0.9 -2.0 -3.1
Serious illness, injury or assault of a close relative in last 2 years 4.0 4.7 7.5 1.8 -2.7 -2.1 -2.6 -1.8 -2.5 -1.2 -1.9 -2.4
Mouth/teeth dental problems: Dentures 1.0 1.8 3.5 -0.9 1.5 1.8 0.4 1.9 0.9 0.4 1.2 1.8
Asthma 1.0 1.9 4.8 1.2 -2.2 -1.4 -2.0 -1.0 -0.5 -0.6 -1.3 -1.2
Medication: Ibuprofen (e.g. Nurofen) 0.8 1.0 4.0 -0.5 0.5 2.0 0.2 0.9 0.8 0.4 0.9 1.5
Medication: Cholesterol lowering 15.2 23.7 46.9 5.0 -6.8 -3.1 -5.4 -3.7 -4.5 -4.5 -4.8 -5.0
Depression (self-reported) 0.6 0.7 1.7 1.0 -1.1 0.6 -0.7 -0.3 0.0 -1.3 -1.0 0.1
Medication: Lansoprazole 2.6 3.0 7.0 -1.0 1.9 2.6 2.0 1.1 1.9 0.2 1.2 2.3
Prospective memory result 2.9 3.5 5.6 -2.0 2.4 1.1 1.9 2.0 2.1 1.5 1.9 1.8
Lung cancer (father) 0.4 0.5 1.1 -0.6 0.5 0.6 1.0 0.3 0.7 0.1 0.6 1.1
Illnesses of mother 1.0 1.2 2.7 1.1 -1.7 -0.6 -1.4 -1.0 -0.9 -1.0 -0.9 -1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.8 9.0 0.6 -2.3 -3.0 -1.8 -0.9 -1.4 0.1 -0.8 -2.0
Pulse wave Arterial Stiffness index 1.3 1.6 2.6 -1.0 1.6 1.4 1.5 1.6 1.0 0.6 0.9 1.4
Impedance of arm (left) 1.7 8.0 24.2 -3.1 -0.3 -4.9 0.5 1.7 2.5 4.9 2.2 -0.4
Arm fat mass (right) 0.7 2.9 5.8 1.9 -2.4 1.1 -2.3 -0.5 -1.4 -2.3 -1.5 -0.6
Trunk predicted mass 2.7 15.7 20.8 3.5 -4.5 -4.1 -4.5 -3.2 -4.3 -2.8 -3.8 -4.6
Standing height 2.1 21.2 104.0 0.2 -4.9 -10.2 -3.7 -1.8 -2.4 2.6 -1.5 -5.5
Length of working week for main job 0.2 0.2 0.6 -0.5 -0.0 0.2 -0.1 0.3 0.7 0.8 0.6 0.5
Exposure to tobacco smoke at home 4.3 4.8 7.3 -1.9 2.5 1.9 2.1 2.7 2.3 1.4 2.0 2.5
Breastfed as a baby 0.4 0.5 1.7 -0.7 0.2 -1.2 0.4 0.5 -0.1 1.3 0.5 -0.2
Tense / ‘highly strung’ 0.8 1.3 3.3 -1.3 0.1 -0.6 1.0 0.8 1.8 1.3 1.3 1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.5 2.2 0.6 -1.5 0.7 -0.7 0.2 0.3 -0.8 -0.7 -0.2
Hair/balding pattern: Pattern 4 0.3 0.6 1.6 1.2 -0.5 0.4 -0.3 -0.5 -0.8 -1.3 -1.0 -0.5
Birth weight of first child 3.5 6.4 16.8 1.6 -3.5 -4.1 -2.4 -2.1 -1.6 -0.6 -2.1 -2.8
Peak expiratory flow (PEF) 2.1 4.8 10.0 1.7 -3.2 -2.5 -2.0 -2.4 -2.2 -1.4 -1.7 -2.0
Pulse wave reflection index 1.4 1.7 5.7 1.6 0.1 2.0 -0.0 -0.6 -1.1 -2.4 -1.2 0.2
Ever highly irritable/argumentative for 2 days 0.4 0.5 2.1 -0.5 0.5 0.7 -0.3 1.5 0.2 0.4 0.6 0.6
Loud music exposure frequency 0.3 0.4 1.4 0.1 -1.2 -0.6 -1.0 -0.2 -0.5 0.2 -0.3 -0.4
Qualifications: O levels/GCSEs or equivalent 0.5 0.9 3.0 -1.1 -0.4 -1.5 0.2 0.1 0.6 1.7 0.9 0.1
Mouth/teeth dental problems: Bleeding gums 3.6 4.6 11.0 2.7 -1.9 1.2 -1.9 -2.2 -1.9 -3.3 -2.2 -0.9
Blood clot in the leg (DVT) 0.1 0.1 0.6 -0.0 0.8 -0.2 0.0 0.4 0.0 0.0 -0.1 -0.1
Medication: Paracetamol 4.9 8.1 16.2 -2.2 3.0 4.0 1.9 3.1 2.8 1.2 2.7 3.7
Headache pain in last month 2.1 3.6 6.2 -1.9 1.0 1.8 1.2 2.3 2.3 1.5 2.1 2.5
Medication for cholesterol, blood pressure or diabetes 3.0 5.0 7.6 -2.6 2.8 1.2 1.8 2.1 1.8 2.6 2.6 2.2
Glaucoma (self-reported) 1.8 2.2 4.1 1.8 -0.8 -0.2 -0.9 -2.0 -1.6 -1.8 -1.8 -1.3
Gout (self-reported) 1.5 2.0 5.1 -1.0 1.9 2.3 1.6 0.8 0.9 0.3 1.2 1.6
Hypothyroidism/myxoedema (self-reported) 4.3 8.3 11.6 -3.3 1.8 2.1 2.4 3.4 2.7 3.2 3.4 3.2
Medication: Amlodipine 1.2 1.7 3.5 1.5 -0.2 -0.6 -0.1 -0.7 -1.7 -1.5 -1.9 -1.8
Medication: Ventolin 100micrograms inhaler 0.2 0.2 0.7 -0.4 -0.4 0.4 -0.3 0.2 0.8 0.3 0.4 0.5
Birth weight 2.4 5.1 11.5 1.6 -2.8 -3.4 -2.1 -1.7 -1.9 -0.7 -2.0 -3.0
Chronic bronchitis/emphysema (mother) 0.8 0.9 4.0 -0.2 0.9 2.0 0.2 0.7 0.6 -0.6 0.6 1.3
High blood pressure (siblings) 0.4 0.6 1.2 -0.8 1.1 0.0 1.1 0.7 0.8 0.8 0.6 0.7
Forced vital capacity (FVC), Best measure 1.6 5.7 21.8 0.7 -3.0 -4.7 -2.3 -0.8 -1.6 0.6 -1.3 -3.1
Body fat percentage 0.4 1.6 8.0 -0.2 -0.4 2.8 -0.1 1.5 0.8 -0.3 0.6 1.7
Leg fat percentage (right) 2.0 7.1 33.3 -0.9 1.7 5.8 1.5 1.9 1.8 -0.6 1.7 3.8
Arm fat-free mass (right) 1.2 6.2 8.9 2.5 -3.0 -1.4 -3.0 -1.8 -3.0 -2.4 -2.5 -2.5
Exposure to tobacco smoke outside home 0.2 0.2 1.2 0.0 -0.2 -0.1 -0.6 1.1 0.3 -0.1 -0.2 -0.3
Comparative body size at age 10 8.1 22.4 31.3 5.6 -4.5 -1.6 -4.4 -4.7 -5.2 -5.6 -5.3 -4.4
Number of full brothers 0.4 0.6 1.6 -0.8 0.4 0.7 0.5 1.3 0.2 0.7 0.9 0.7
Worry too long after embarrassment 1.2 2.0 5.2 -1.2 1.0 2.3 1.8 0.3 1.2 0.7 1.3 1.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.2 0.5 -0.3 1.1 -0.2 -0.5 0.8 -1.0 -0.5 0.3
Wheeze or whistling in the chest in last year 0.4 0.8 4.5 0.0 0.2 2.1 0.4 0.3 0.9 -0.6 0.1 1.0
Number of children fathered 0.3 0.3 1.0 -0.4 -0.4 0.2 -0.1 1.0 0.4 0.3 0.5 0.9
Reason for reducing amount of alcohol drunk: Health precaution 2.8 3.3 4.9 -1.7 2.2 1.6 1.8 1.7 1.9 1.5 1.9 1.9
Age at first live birth 8.8 15.6 30.9 3.2 -3.7 -5.6 -3.1 -4.2 -4.2 -2.0 -3.6 -4.9
Pulse wave peak to peak time 1.7 2.0 4.1 0.8 -1.8 -2.0 -1.6 -1.5 -1.0 -0.2 -0.8 -1.7
Health satisfaction 0.7 0.8 2.3 1.1 -0.4 1.3 -0.7 -0.8 -0.1 -1.5 -1.0 -0.1
Shortness of breath walking on level ground 0.2 0.2 1.3 0.2 0.8 1.1 0.2 -0.2 -0.1 -0.4 -0.1 0.3
Qualifications: College or University degree 3.9 12.4 18.2 3.0 -4.1 -4.2 -3.2 -4.3 -2.8 -2.0 -3.4 -4.0
Eye problems/disorders: None of the above 0.4 0.5 1.6 0.2 -1.2 -0.7 -1.3 0.2 -0.2 0.1 -0.1 -0.7
Mouth/teeth dental problems: Loose teeth 2.1 2.5 3.9 -1.9 1.5 1.2 1.4 1.2 1.4 1.5 2.0 1.9
Emphysema/chronic bronchitis 0.2 0.3 1.8 0.1 0.0 1.3 0.4 -0.1 0.4 -0.5 0.1 0.4
Medication for pain relief, constipation, heartburn 1.2 2.0 10.5 0.1 -0.7 -3.2 -0.4 -1.1 -1.2 0.8 -0.5 -1.8
Neck or shoulder pain in last month 2.9 4.1 5.8 -2.2 1.6 1.7 1.8 2.4 2.0 2.0 2.2 2.3
Medication: Blood pressure 0.2 0.3 1.6 0.0 0.5 0.7 1.3 0.2 0.7 -0.3 -0.1 0.4
Angina (self-reported) 2.5 3.3 5.9 2.2 -2.4 -0.0 -1.7 -1.5 -1.1 -2.1 -2.3 -1.6
Migraine (self-reported) 0.5 0.6 1.6 0.9 -1.3 1.1 -0.3 0.4 0.2 -1.1 -0.7 -0.1
Medication: Ibuprofen 1.7 2.0 7.5 -0.8 1.2 2.7 0.5 1.2 1.4 0.5 1.1 1.9
Medication: Allopurinol 2.5 3.3 7.7 -1.4 2.0 2.8 2.0 1.3 1.4 0.7 1.6 2.2
Medication: Omeprazole 1.2 1.4 3.2 1.5 -1.1 0.6 -0.7 -1.1 -1.1 -1.8 -1.4 -0.6
Medication: Seretide 50 evohaler 0.3 0.4 1.0 0.5 -0.9 -0.4 -1.0 -0.1 -0.2 -0.6 -0.6 -0.5
Mean time to correctly identify matches 0.8 1.5 3.4 1.4 -0.9 1.5 -0.9 -1.7 -0.1 -1.9 -1.2 -0.0
Heart disease (mother) 1.6 2.0 2.9 1.5 -1.4 -1.0 -1.5 -1.7 -1.1 -1.3 -1.5 -1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 3.6 4.2 9.6 2.2 -1.5 -1.3 -2.0 -3.1 -2.0 -2.2 -2.0 -1.7
Whole body fat mass 0.4 1.5 5.0 1.2 -2.2 0.9 -1.8 0.1 -0.9 -1.4 -0.9 -0.2
Leg fat mass (right) 0.5 1.8 10.2 0.7 -0.7 3.2 -0.6 0.3 -0.2 -1.6 -0.2 1.3
Arm predicted mass (right) 1.3 6.4 8.9 2.6 -3.0 -1.4 -2.9 -1.9 -3.0 -2.5 -2.6 -2.5
Pulse rate, automated reading 0.7 2.4 3.8 -1.7 1.5 0.7 0.6 2.0 1.8 1.8 1.7 1.4
Alcohol intake frequency. 1.4 3.2 7.3 -1.6 1.1 1.8 1.5 2.7 1.4 1.5 1.8 2.0
Comparative height size at age 10 3.1 16.9 49.8 2.6 -4.8 -7.1 -3.7 -3.1 -3.3 -0.7 -3.4 -5.2
Number of full sisters 1.1 1.3 2.9 -1.2 0.5 1.3 1.2 1.7 0.7 0.9 1.1 1.3
Suffer from ‘nerves’ 1.2 1.8 4.5 -1.5 0.6 -0.3 -0.0 1.9 2.1 1.6 1.4 1.0
Overall health rating 2.7 5.9 17.1 -1.6 1.5 4.1 1.9 2.4 2.8 0.7 1.8 3.2
Chest pain or discomfort 0.7 1.0 5.6 0.4 0.7 2.4 -0.0 -0.3 0.1 -1.2 -0.1 0.9
Had major operations 3.4 4.0 5.9 2.1 -1.7 -1.8 -2.2 -2.4 -1.7 -1.8 -2.1 -2.0
Age at last live birth 4.8 7.0 12.4 2.3 -2.4 -3.5 -1.9 -3.1 -2.8 -1.3 -2.6 -3.2
Family relationship satisfaction 0.2 0.2 0.6 0.6 -0.3 0.4 -0.2 -0.3 -0.2 -0.8 -0.6 -0.2
Leg pain on walking 0.3 0.4 1.9 -0.1 0.6 1.4 0.4 0.6 0.4 -0.0 0.0 0.6
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 4.9 -0.7 0.3 2.2 1.0 0.8 0.7 0.3 0.9 1.6
Commuting to job workplace: Car/motor vehicle 0.9 1.1 2.1 -1.1 1.1 1.0 0.1 1.2 0.5 0.8 1.3 1.4
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 2.7 -1.0 1.0 0.1 1.6 1.2 0.2 1.3 0.8 0.5
Medication: Aspirin 1.1 1.5 3.1 1.5 -1.0 -0.2 -0.9 -1.5 -1.2 -1.8 -1.4 -0.9
Supplements: Vitamin C 1.0 1.2 3.6 -1.1 0.6 0.7 0.3 1.4 1.9 1.0 1.0 1.1
Knee pain experienced in last month 0.1 0.1 0.4 0.1 -0.0 0.5 0.2 0.7 0.2 -0.3 -0.3 0.3
Hypertension (Self-reported) 0.3 0.9 2.9 0.3 1.6 1.3 1.7 0.2 -0.2 -0.8 -0.4 0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 3.0 0.5 0.7 1.7 0.8 0.4 -0.2 -1.2 -0.3 0.6
Illnesses of father: Heart disease 6.3 8.8 10.8 2.9 -3.1 -3.2 -3.3 -3.2 -2.3 -2.2 -2.9 -3.2
Illnesses of siblings: Diabetes 8.6 10.6 16.8 -2.6 3.8 4.1 4.0 2.3 3.1 1.8 2.8 4.0
Smoking status: Previous 0.0 0.0 0.1 0.1 0.0 0.3 0.1 -0.2 -0.3 -0.3 0.1 0.2
Forced expiratory volume in 1-second (FEV1), predicted 1.4 2.9 11.5 -1.7 -1.0 -3.4 -0.5 0.7 0.9 2.8 1.1 -0.6
Whole body fat-free mass 3.3 18.9 28.0 4.0 -5.3 -4.2 -5.0 -3.3 -4.6 -3.1 -4.1 -4.9
Leg fat-free mass (right) 4.8 25.5 43.1 4.7 -6.6 -4.7 -5.8 -3.6 -5.2 -3.6 -4.9 -5.7
Arm fat percentage (left) 0.4 1.8 3.9 1.4 -2.0 1.7 -1.6 0.0 -0.6 -1.8 -1.0 0.1
Average weekly red wine intake 0.6 0.9 3.3 -1.4 0.4 -0.5 0.5 0.4 0.7 1.8 1.2 0.7
Handedness (chirality/laterality): Left-handed 0.7 0.9 5.0 0.1 -0.4 -2.2 -0.0 -0.6 -0.4 0.4 -0.5 -1.3
Mood swings 0.3 0.6 1.3 -0.6 -0.4 1.1 0.3 1.0 0.6 0.6 0.8 1.1
Loneliness, isolation 1.4 1.9 7.6 -0.4 0.8 2.8 1.2 1.1 1.5 -0.4 0.7 1.9
Long-standing illness, disability or infirmity 0.6 0.9 3.3 0.7 -0.0 1.8 0.5 -0.5 0.8 -1.4 -0.6 0.7
Ever had bowel cancer screening 0.5 0.6 1.5 -0.7 0.1 0.8 0.5 1.0 1.2 0.6 0.6 0.9
Diabetes diagnosed by doctor 3.4 5.6 12.6 -1.4 3.3 3.5 3.4 0.8 1.9 0.5 1.3 2.7
Ever had stillbirth, spontaneous miscarriage or termination 3.8 4.0 8.0 -1.8 2.4 1.6 2.8 1.9 1.6 1.5 2.0 2.1
Friendships satisfaction 0.5 0.6 1.8 0.8 -0.9 0.6 -0.2 -0.3 -1.4 -0.9 -0.8 -0.6
Qualifications: nursing, teaching 5.0 7.8 10.4 2.6 -2.9 -3.2 -2.6 -3.2 -2.1 -2.2 -2.9 -3.2
Commuting to job workplace: Walk 2.8 3.1 5.8 1.7 -2.4 -0.6 -1.5 -2.0 -1.8 -2.1 -1.6 -1.5
Eye problems/disorders: Cataract 0.4 0.5 1.0 -0.5 0.7 0.9 0.8 0.5 0.9 0.4 0.4 1.0
Mouth/teeth dental problems: Mouth ulcers 4.4 7.0 10.2 -3.1 2.2 1.7 2.2 2.5 2.6 2.8 3.1 3.2
Medication for cholesterol 1.1 1.6 4.7 1.0 -2.2 -1.1 -1.5 -1.0 -1.3 -0.7 -0.9 -1.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.9 3.4 6.0 -1.9 1.2 1.8 1.8 2.5 1.6 1.8 1.8 2.1
Back pain experienced in last month 2.0 2.8 6.2 2.0 -2.5 1.3 -0.8 -1.0 -1.8 -2.3 -1.7 -0.9
Mineral and other dietary supplements 0.7 1.0 2.1 -1.0 0.6 0.8 0.9 0.6 1.1 1.0 1.1 1.5
Breast cancer (self-reported) 3.5 4.2 7.1 -2.2 1.8 0.5 1.6 2.2 2.7 2.5 2.3 1.9
Asthma (self-reported) 0.7 1.4 3.7 1.1 -1.9 -1.1 -1.8 -0.7 -0.4 -0.5 -1.2 -1.0
Osteoporosis (self-reported) 0.4 0.5 3.2 0.1 0.4 1.8 0.2 -0.2 0.3 -0.5 -0.1 0.7
Osteoarthritis (self-reported) 1.6 2.1 5.3 -0.9 0.7 2.3 0.2 1.5 2.0 0.4 1.1 2.1
Medication: Aspirin 1.5 2.0 4.7 1.8 -0.9 -0.1 -1.0 -1.7 -1.4 -2.2 -1.6 -1.0
Medication: Gliclazide 4.8 5.5 11.1 -1.8 2.7 3.3 2.9 1.1 2.5 1.1 1.9 2.6
Illnesses of father: None of the above (group 1) 1.6 2.0 4.4 -1.2 1.4 2.1 1.9 1.1 1.0 0.8 1.1 1.6
Smoking status: Current 3.6 5.7 9.1 -2.1 2.3 2.9 2.0 3.0 2.6 1.6 2.3 2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 1.9 1.2 -0.6 0.4 -0.5 -0.8 -0.7 -1.4 -1.0 -0.5
Whole body water mass 3.3 19.0 27.5 4.0 -5.2 -4.1 -5.0 -3.4 -4.7 -3.3 -4.2 -4.9
Leg predicted mass (right) 4.8 25.6 43.0 4.7 -6.6 -4.7 -5.8 -3.7 -5.2 -3.6 -4.9 -5.7
Arm fat mass (left) 0.7 3.0 6.6 1.9 -2.6 0.9 -2.2 -0.6 -1.4 -2.3 -1.6 -0.7
Number of self-reported non-cancer illnesses 0.5 0.9 3.7 -0.1 -0.1 1.9 0.6 0.7 1.3 -0.6 0.0 1.2
Average weekly champagne plus white wine intake 2.6 3.5 5.0 1.9 -1.8 -1.4 -2.0 -1.9 -2.2 -1.6 -1.9 -2.1
Miserableness 0.3 0.5 2.0 0.5 -1.4 1.1 -0.5 0.5 0.2 -0.8 -0.2 0.2
Guilty feelings 2.3 3.4 9.1 2.2 -1.2 1.5 -0.6 -2.6 -1.4 -3.0 -1.9 -0.6
Wears glasses or contact lenses 0.3 0.4 1.0 -0.7 0.2 -0.1 0.4 1.0 0.7 0.8 0.5 0.6
Ever taken oral contraceptive pill 1.2 1.3 3.6 1.5 -0.6 0.5 -0.8 -0.8 -1.4 -1.9 -1.2 -0.9
Hearing aid user 0.6 0.7 2.2 1.1 -0.9 0.3 -0.7 -0.4 -0.5 -1.5 -0.9 -0.6
Mother’s age at death 7.3 9.1 13.2 3.4 -2.4 -1.7 -3.1 -3.6 -2.8 -3.1 -3.3 -3.1
Financial situation satisfaction 3.1 3.9 5.0 2.2 -2.2 -1.0 -2.0 -1.4 -2.1 -2.0 -2.2 -2.1
Tinnitus: Yes, now most or all of the time 0.8 0.9 4.3 -0.7 0.1 0.9 0.5 2.1 0.9 0.6 0.8 1.0
Commuting to job workplace: Public transport 1.7 2.0 3.2 1.5 -1.5 -1.0 -1.1 -1.8 -0.8 -1.5 -1.6 -1.5
Eye problems/disorders: Glaucoma 3.5 4.1 7.6 2.3 -1.6 -1.2 -1.3 -2.8 -2.1 -2.1 -2.4 -2.2
Medication: Blood pressure 1.7 3.1 9.8 -1.3 3.1 1.5 2.4 1.5 1.3 0.9 1.2 1.7
Pain type(s) experienced in last month: Hip pain 2.9 3.6 6.9 -1.7 1.9 2.6 1.6 1.9 1.6 1.1 1.9 2.3
Supplements: Fish oil (including cod liver oil) 0.5 0.7 1.7 1.0 -0.1 -0.3 -0.3 -0.8 -0.8 -0.8 -1.1 -1.3
High cholesterol (Self-reported) 17.0 30.1 47.9 5.6 -6.9 -4.5 -6.3 -3.9 -5.3 -4.8 -5.6 -5.9
Medication: Bendroflumethiazide 0.6 1.0 1.9 -0.9 1.1 0.4 1.4 0.4 1.2 0.7 1.0 1.2
Medication: Paracetamol 2.7 4.1 8.5 -1.4 2.3 2.9 1.0 2.3 2.0 0.7 1.8 2.7
Medication: Lisinopril 0.7 0.9 1.8 1.3 -0.6 -0.2 -0.4 -1.1 -0.6 -1.2 -1.4 -1.0
Medication: Atorvastatin 5.8 7.2 12.8 2.7 -3.5 -2.2 -3.6 -1.6 -2.0 -2.4 -2.6 -2.8
Illnesses of father: High blood pressure 0.4 0.5 1.7 -0.6 1.3 0.7 0.8 0.6 0.2 0.6 0.6 0.5
Alcohol drinker status: Never 0.1 0.1 0.7 0.1 -0.3 -0.8 0.2 -0.0 -0.3 -0.2 -0.2 -0.5
Ever smoked 0.2 0.4 0.6 0.7 -0.7 -0.3 -0.4 -0.6 -0.7 -0.8 -0.6 -0.5
Basal metabolic rate 2.8 15.5 25.8 3.6 -5.1 -3.5 -4.7 -2.9 -4.2 -2.9 -3.8 -4.3
Leg fat percentage (left) 2.0 7.3 36.4 -0.8 1.7 6.0 1.5 2.0 1.6 -0.8 1.6 3.8
Arm fat-free mass (left) 1.2 6.0 9.2 2.4 -3.0 -1.5 -2.8 -1.7 -3.0 -2.3 -2.4 -2.5
Number of operations (self-reported) 0.6 0.9 2.5 0.9 -1.6 -0.6 -1.6 -0.5 -0.4 -0.9 -0.9 -0.5
Average weekly beer plus cider intake 0.9 1.4 2.2 -1.2 1.3 0.9 1.5 1.5 1.0 1.0 1.1 1.0
Irritability 0.6 1.0 3.0 -0.5 -1.7 -1.7 -0.6 0.9 0.4 1.2 0.2 -0.6
Risk taking 2.8 4.2 7.4 -2.5 1.4 0.0 1.1 2.4 2.7 2.6 2.3 1.8
Ever had prostate specific antigen (PSA) test 0.5 0.6 2.0 0.9 -0.7 0.0 -0.4 -0.8 -0.6 -1.4 -0.7 -0.3
Fractured/broken bones in last 5 years 0.3 0.4 0.8 0.8 0.0 0.2 -0.9 -0.7 -0.4 -0.9 -0.8 -0.5
Age started oral contraceptive pill 0.8 1.0 3.2 -1.1 -0.4 -1.8 -0.1 0.3 0.9 1.6 0.8 -0.0
Diastolic blood pressure, automated reading 1.7 5.3 11.8 -1.6 3.2 3.4 2.4 2.3 1.1 0.9 1.8 2.6
Ever depressed for a whole week 0.5 0.7 1.4 1.1 -0.6 -0.4 -0.4 0.0 -0.8 -0.9 -1.2 -1.1
Unable to work because of sickness or disability 1.7 2.2 3.7 -1.2 1.1 1.7 1.6 1.5 1.9 0.6 1.3 1.9
Commuting to job workplace: Cycle 2.9 3.4 6.6 1.4 -2.6 -2.3 -1.9 -1.9 -1.8 -1.0 -1.4 -1.9
Myopia 9.3 13.5 20.2 -4.2 3.8 1.1 3.5 3.1 4.4 4.5 4.0 3.4
Vascular/heart problems diagnosed by doctor 0.3 0.8 2.0 -0.7 -1.2 -1.4 -1.2 0.0 0.3 1.2 0.7 -0.3
Cholesterol lowering medication 0.8 1.1 3.8 0.7 -1.1 -1.9 -1.2 -0.4 -0.4 -0.1 -1.1 -1.4
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 2.6 1.4 -0.7 0.9 -0.4 -0.7 -0.8 -1.6 -1.3 -0.4
Pain experienced in last month 1.2 2.1 8.2 0.8 -0.4 -2.9 -0.9 -2.0 -1.0 -0.2 -0.9 -1.8
Supplements: Calcium 2.6 2.8 3.7 -1.6 1.9 1.7 1.3 1.9 1.8 1.4 1.5 1.8
Basal cell carcinoma (self-reported) 0.3 0.3 1.5 -0.3 0.3 -0.1 0.6 0.8 1.2 0.5 0.0 -0.1
Heart attack/myocardial infarction (self-reported) 0.2 0.2 0.6 -0.4 -0.4 -0.8 -0.3 0.2 0.6 0.6 0.4 0.3
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.2 0.1 0.5 -0.5 -0.1 0.1 0.0 0.0 -0.2 -0.3
Heart disease (siblings) 1.8 2.2 3.5 1.6 -1.9 -1.2 -1.5 -0.8 -1.1 -1.4 -1.9 -1.6
Alcohol drinker status: Previous 1.7 1.9 4.2 -1.1 1.2 2.0 0.7 1.6 1.2 0.9 1.1 1.9
Pack years of smoking 1.0 1.4 3.5 -1.1 1.7 0.2 0.6 0.8 1.9 1.1 1.2 1.4
Impedance of whole body 4.7 24.0 50.8 -6.2 3.7 -0.9 4.1 4.6 5.6 7.1 5.6 3.6
Leg fat mass (left) 0.5 1.9 10.7 0.8 -0.8 3.3 -0.6 0.3 -0.3 -1.7 -0.2 1.3
Arm predicted mass (left) 1.1 5.5 8.2 2.3 -2.9 -1.3 -2.8 -1.7 -2.9 -2.2 -2.3 -2.3