Best TWAS P=6.94e-09 · Best GWAS P=1.2e-08 conditioned to 0.185
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | STX6 | 0.10 | 0.11 | enet | 12 | 0.11 | 4.9e-13 | 5.6 | 5.6 | 2.0e-08 | 0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Liver | RP11-46A10.4 | 0.19 | 0.02 | enet | 15 | 0.06 | 8.9e-03 | -4.3 | 5.4 | 5.9e-08 | 0.83 | 0.02 | 0.85 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | MR1 | 0.10 | 0.06 | lasso | 7 | 0.07 | 2.2e-06 | 5.7 | 5.8 | 6.9e-09 | 0.87 | 0.00 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | STX6 | 0.06 | 0.03 | enet | 8 | 0.03 | 2.8e-03 | 4.7 | 5.6 | 2.1e-08 | 0.71 | 0.03 | 0.52 | FALSE |