Best TWAS P=4.55e-09 · Best GWAS P=1.28e-10 conditioned to 0.00071
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | AAGAB | 0.06 | 0.05 | enet | 11 | 0.05 | 3.2e-07 | -5.0 | -5.9 | 4.6e-09 | 0.67 | 0.03 | 0.97 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | IQCH | 0.13 | 0.11 | bslmm | 597 | 0.10 | 5.9e-12 | -6.2 | 5.2 | 1.8e-07 | -0.57 | 0.03 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | IQCH | 0.06 | 0.05 | blup | 112 | 0.06 | 5.2e-12 | -6.3 | 5.3 | 1.3e-07 | -0.65 | 0.02 | 0.98 | FALSE |