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Forced vital capacity (FVC)
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chr15:66,797,492-68,492,262
Best TWAS P=4.55e-09 · Best GWAS P=1.28e-10 conditioned to 0.00071
66.8M
67M
67.2M
67.4M
67.6M
67.8M
68M
68.2M
68.4M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
AAGAB
0.06
0.05
enet
11
0.05
3.2e-07
-5.0
-5.9
4.6e-09
0.67
0.03
0.97
TRUE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
IQCH
0.06
0.05
blup
112
0.06
5.2e-12
-6.3
5.3
1.3e-07
-0.65
0.02
0.98
FALSE
2
CommonMind
Brain Pre-frontal Cortex
IQCH
0.13
0.11
bslmm
597
0.10
5.9e-12
-6.2
5.2
1.8e-07
-0.57
0.03
0.97
FALSE