Best TWAS P=1.16e-08 · Best GWAS P=3.85e-14 conditioned to 1.15e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Colon Adenocarcinoma | HAPLN3 | 0.14 | 0.04 | lasso | 4 | 0.08 | 1.7e-05 | 1.7 | -5.7 | 1.2e-08 | 0.19 | 0.12 | 0.11 | TRUE |
| 2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | MFGE8 | 0.18 | 0.01 | lasso | 4 | 0.04 | 9.9e-03 | 4.2 | -5.4 | 6.2e-08 | 0.18 | 0.04 | 0.04 | TRUE |