TWAS hub - MFGE8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.3370	0.0940	1.5e-03	0.069	NA	0.088	NA	0.107	1.2e-04	NA	1.4e-05	NA	1.7e-06
2	GTEx	Cells Transformed fibroblasts	0.2460	0.0490	1.6e-08	0.104	NA	0.180	NA	0.168	3.3e-08	NA	1.8e-13	NA	1.2e-12
3	GTEx	Colon Transverse	0.1710	0.0700	7.0e-03	0.051	NA	0.018	NA	0.046	1.8e-03	NA	4.4e-02	NA	3.0e-03
4	GTEx	Heart Left Ventricle	0.1124	0.0438	5.9e-03	0.027	NA	0.034	NA	0.046	1.3e-02	NA	6.3e-03	NA	1.8e-03
5	GTEx	Lung	0.1174	0.0409	2.7e-03	0.036	NA	0.052	NA	0.063	8.3e-04	NA	8.0e-05	NA	1.4e-05
6	GTEx	Nerve Tibial	0.2064	0.0572	2.3e-05	0.074	NA	0.118	NA	0.106	6.2e-06	NA	1.0e-08	NA	6.3e-08
7	GTEx	Spleen	0.4720	0.1070	6.3e-04	0.270	NA	0.228	NA	0.249	1.3e-07	NA	1.5e-06	NA	4.4e-07
8	GTEx	Whole Blood	0.1170	0.0350	5.2e-05	0.139	NA	0.124	NA	0.127	9.8e-13	NA	1.6e-11	NA	9.3e-12
9	METSIM	Adipose	0.0746	0.0261	1.9e-04	0.040	0.030	0.009	0.034	0.025	9.1e-07	1.9e-05	1.2e-02	6.0e-06	8.5e-05
10	YFS	Blood	0.1868	0.0260	0.0e+00	0.162	0.142	0.162	0.173	0.168	1.4e-50	6.0e-44	1.6e-50	3.2e-54	1.4e-52
11	TCGA	Breast Invasive Carcinoma	0.0565	0.0196	1.7e-06	0.036	0.027	0.023	NA	0.022	4.8e-08	2.9e-06	1.2e-05	NA	1.6e-05
12	TCGA	Colon Adenocarcinoma	0.0920	0.0510	4.5e-03	0.044	0.028	0.006	NA	0.028	1.4e-03	8.9e-03	1.4e-01	NA	8.9e-03
13	TCGA	Esophageal Carcinoma	0.2260	0.0940	8.2e-04	0.141	0.034	0.072	NA	0.077	3.1e-05	3.1e-02	2.7e-03	NA	2.0e-03
14	TCGA	Brain Lower Grade Glioma	0.0580	0.0236	1.9e-04	0.023	0.035	0.024	NA	0.029	1.0e-03	7.1e-05	8.2e-04	NA	2.4e-04
15	TCGA	Lung Adenocarcinoma	0.0547	0.0203	4.0e-05	0.042	0.030	0.060	NA	0.062	1.1e-05	1.7e-04	1.4e-07	NA	8.2e-08
16	TCGA	Lung Squamous Cell Carcinoma	0.0578	0.0263	2.6e-04	0.040	0.027	0.038	NA	0.027	2.0e-05	3.9e-04	3.7e-05	NA	3.9e-04
17	TCGA	Pancreatic Adenocarcinoma	0.0980	0.0490	9.2e-03	0.002	0.046	0.053	NA	0.023	2.5e-01	5.2e-03	3.0e-03	NA	3.8e-02
18	TCGA	Pheochromocytoma and Paraganglioma	0.1760	0.0820	8.3e-03	0.014	0.015	0.033	NA	0.041	8.9e-02	7.9e-02	1.9e-02	NA	9.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Medication: Bendroflumethiazide	5.0	7.6	19.4	2.2	3.7	2.0	1.6	2.8	1.8	3.9	-3.2	2.7	4.4	1.2	2.5	2.3	4.0	2.6	1.4	2.5	2.2
Comparative height size at age 10	3.4	18.5	99.4	5.8	2.6	4.5	4.3	4.7	5.1	-4.1	-5.6	0.9	-2.3	-1.6	2.5	2.6	-4.9	-0.8	0.4	-3.6	-10.0
Alcohol intake versus 10 years previously	3.3	4.9	9.5	-1.5	-3.1	-1.2	-2.1	-2.2	-2.0	-2.0	2.4	-2.7	-3.1	-1.4	-2.4	-2.8	-2.0	-2.1	-2.4	-2.4	-0.2
HbA1C	3.0	3.4	8.6	-1.1	1.9	0.4	1.5	1.2	0.5	2.5	-0.7	1.1	1.9	2.5	2.3	1.2	1.9	2.7	2.4	2.9	1.3
Height	2.9	55.8	278.9	6.2	4.7	8.5	8.7	8.6	10.4	-7.2	-9.8	2.2	-4.1	-2.0	6.3	5.7	-8.0	-1.9	1.6	-4.3	-16.7
Mouth/teeth dental problems: Bleeding gums	2.8	3.6	9.1	1.7	-1.6	-0.5	-1.0	-1.3	0.0	-2.2	0.5	-0.9	-2.1	-3.0	-2.6	-1.6	-2.0	-2.5	-2.4	-2.7	-1.9
Long-standing illness, disability or infirmity	2.8	4.4	10.3	0.6	2.5	0.9	0.4	1.5	0.3	2.7	-1.2	1.1	2.5	2.7	2.4	1.4	3.2	3.1	2.8	2.0	2.4
Standing height	2.7	26.9	112.8	4.9	4.6	6.6	6.4	7.2	7.2	-3.7	-7.4	1.4	-1.5	-0.7	4.8	4.3	-3.7	-0.2	2.1	-2.1	-10.6
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.0	31.4	1.5	1.1	2.7	1.7	3.2	3.5	-1.5	-3.4	0.8	-0.6	-1.2	1.3	1.1	-1.6	-0.1	0.4	-1.3	-5.6
Serious illness, injury or assault of a close relative in last 2 years	2.3	2.7	9.9	-1.7	-1.6	-3.1	-1.8	-3.1	-2.5	-0.4	1.9	-1.6	-1.2	0.3	-1.4	-1.0	-0.9	0.1	-0.3	-0.4	1.4
Schizophrenia (2014)	2.2	4.8	16.0	-0.9	2.9	3.5	3.6	4.0	2.1	0.5	-2.6	1.4	1.1	1.0	3.0	1.9	0.8	0.1	1.1	2.1	-0.7
Sitting height	2.2	15.4	40.6	2.5	3.6	4.9	5.6	5.2	5.9	-2.3	-5.9	1.7	-0.3	1.1	4.9	4.2	-2.3	0.3	3.0	0.4	-6.4
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	8.3	0.7	0.7	2.6	1.8	2.2	2.6	0.3	-2.1	2.9	1.9	-0.3	1.6	2.1	0.5	0.3	0.9	0.8	-1.2
Emphysema/chronic bronchitis	2.1	2.4	5.3	0.5	-1.4	-0.7	-0.5	-1.0	-1.4	-1.5	1.2	-2.3	-2.0	-1.8	-1.8	-2.1	-1.6	-1.5	-2.0	-1.9	-1.0
Commuting to job workplace: Cycle	2.0	2.4	10.6	0.6	1.3	0.4	-0.7	0.5	-0.4	2.9	-0.6	1.6	3.3	0.5	0.2	0.3	3.2	2.1	0.8	0.8	1.3
Medication: Atenolol	1.9	2.4	4.7	1.2	1.6	1.9	1.9	1.9	1.3	1.6	-1.0	1.6	1.6	2.2	1.5	1.1	0.8	1.8	1.6	1.8	0.8
Chronic bronchitis/emphysema (father)	1.9	2.2	8.4	-0.5	-0.8	-0.8	-0.4	-0.7	-1.4	-0.5	2.6	-2.3	-1.3	-1.3	-2.1	-2.9	-0.6	-1.2	-1.9	-0.9	-1.0
Peak expiratory flow (PEF)	1.9	4.5	17.1	2.2	-2.4	-0.6	-0.3	-0.7	0.2	-2.8	0.9	-1.9	-2.3	-2.9	-2.4	-1.5	-2.0	-2.0	-2.0	-4.1	-2.7
Leg fat percentage (right)	1.9	6.8	14.5	1.4	-2.5	-2.3	-2.5	-3.0	-3.0	-1.6	3.6	-3.8	-2.0	-1.2	-3.7	-3.1	-2.3	-0.9	-2.1	-3.7	-0.8
Guilty feelings	1.9	2.9	10.0	0.4	-1.4	1.6	1.5	0.8	-0.2	-3.2	-0.0	-1.4	-2.8	-0.2	-1.0	-1.6	-2.7	-1.4	0.3	-1.2	-3.2
Leg fat percentage (left)	1.9	6.8	13.2	1.2	-2.9	-2.4	-2.2	-3.1	-2.9	-2.2	3.6	-3.6	-2.5	-1.0	-3.5	-2.8	-2.7	-1.3	-1.9	-3.5	-0.5
Myopia	1.9	2.8	9.8	-0.8	-1.4	-2.0	-1.1	-1.4	-1.2	-1.6	0.0	-1.2	-1.3	-2.4	-1.3	-0.7	-1.6	-2.2	-2.2	-1.9	-3.1
Bipolar Disorder or Schizophrenia	1.8	4.5	12.9	-0.5	2.3	2.9	3.1	3.6	2.8	0.6	-3.3	1.6	1.1	0.2	2.8	2.7	0.3	0.3	0.8	1.6	-1.7
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	6.5	1.2	0.9	1.9	1.5	1.4	2.5	-0.1	-0.9	1.5	0.8	1.2	1.1	2.0	-0.5	0.9	2.1	1.1	0.5
Average weekly champagne plus white wine intake	1.8	2.5	8.0	-0.3	0.4	2.0	1.4	1.9	2.6	-0.5	-2.5	2.8	0.7	0.7	1.8	2.3	0.1	0.2	1.6	1.1	0.5
Supplements: Calcium	1.8	2.0	6.6	-0.9	-0.6	-1.1	-1.1	-1.3	-2.1	-0.3	2.2	-2.6	-1.2	0.0	-2.2	-2.2	-0.6	-0.5	-1.0	-1.1	0.7
LDL Cholesterol	1.7	2.7	7.7	-0.0	1.0	0.9	1.6	0.8	1.3	0.8	-1.8	2.8	0.8	2.4	1.6	2.2	-0.3	2.2	2.6	2.0	1.4
Alzheimer’s Disease (in father)	1.6	1.7	4.2	1.9	1.3	1.2	0.4	0.9	0.4	2.0	0.0	0.3	1.3	1.8	0.5	-0.1	1.7	2.1	1.4	1.5	1.7
Hearing difficulty/problems with background noise	1.6	2.6	7.7	0.8	2.1	1.9	1.0	2.5	-0.0	2.1	-1.2	-0.3	2.1	0.9	1.5	0.4	2.8	1.7	1.3	2.0	0.3
Supplements: Vitamin C	1.6	1.9	4.9	2.2	-1.4	-1.6	-1.6	-2.1	-2.0	-0.4	0.9	-0.8	-0.9	-0.9	-1.9	-0.9	-1.2	-0.4	-1.4	-1.6	0.2
Schizophrenia (2018)	1.5	3.2	8.3	-0.3	2.1	2.5	2.6	2.9	2.1	0.0	-2.4	1.3	1.0	0.7	2.8	2.0	0.3	-0.0	1.1	1.7	-1.2
Forced vital capacity (FVC)	1.5	6.0	29.3	2.8	1.8	2.1	2.2	3.1	4.0	-1.1	-3.8	1.4	0.6	-1.2	1.6	2.1	-1.1	0.7	0.9	-1.7	-5.4
Breastfed as a baby	1.5	1.8	4.2	0.4	1.7	1.0	0.6	1.6	-0.2	1.9	0.1	0.4	1.6	2.0	1.0	-0.2	2.0	1.7	1.7	1.9	0.9
Chronic bronchitis/emphysema (mother)	1.5	1.7	5.7	0.1	-0.3	2.3	1.5	1.3	2.4	-1.6	-1.5	1.2	-0.6	-1.2	0.8	1.1	-0.9	-1.6	-0.3	-0.2	-1.5
Forced vital capacity (FVC), Best measure	1.5	5.4	24.3	2.7	2.2	2.1	2.1	3.4	3.9	-0.3	-3.3	1.2	0.9	-0.6	1.8	1.8	-0.5	1.2	1.2	-1.0	-4.9
Body fat percentage	1.5	6.1	17.6	2.2	-2.2	-1.6	-1.1	-2.1	-1.9	-2.4	2.7	-3.3	-2.8	-1.6	-3.1	-2.3	-3.4	-1.0	-1.9	-4.2	-2.4
Worry too long after embarrassment	1.5	2.5	8.7	0.5	1.1	3.0	2.9	2.1	1.9	-1.1	-1.1	0.8	-0.5	2.0	1.5	0.0	-1.0	0.4	2.0	1.2	-1.3
Heart disease (mother)	1.5	1.8	9.0	3.0	0.8	-0.4	-1.6	0.3	-0.7	2.3	1.0	-0.6	1.4	1.1	-0.7	-0.7	1.7	2.3	0.9	-0.1	0.1
Leg pain on walking	1.5	1.9	6.9	0.2	0.7	2.2	2.6	1.8	1.9	-0.6	-0.7	1.5	0.1	1.2	1.7	1.4	0.3	-0.0	1.5	1.3	0.7
Knee pain experienced in last month	1.5	2.4	7.3	1.5	-1.6	-0.4	0.7	-0.1	-0.9	-1.7	0.6	-1.5	-1.8	-2.0	-1.3	-1.1	-2.2	-1.8	-1.7	-1.5	-2.7
Average weekly red wine intake	1.5	2.2	6.6	-0.2	-0.0	-2.1	-1.9	-1.9	-2.6	1.3	1.7	-1.3	0.8	0.9	-1.5	-1.2	1.1	1.3	0.3	-0.4	2.5
Number of operations (self-reported)	1.5	2.2	7.2	0.6	-2.1	-0.1	-1.3	0.4	-1.5	-1.3	1.7	-1.8	-1.2	-1.3	-1.8	-1.9	-0.2	-1.4	-1.5	-2.7	-1.3
Heart disease (siblings)	1.5	1.9	7.3	1.6	1.0	-0.7	-1.3	-0.6	-1.7	0.9	2.4	-1.9	-0.3	-0.1	-2.1	-2.7	0.6	0.5	-0.9	-0.9	0.5
Schizophrenia vs Biploar Disorder	1.4	1.8	5.2	0.3	0.8	1.6	1.3	1.5	1.4	-0.1	-1.6	1.9	1.1	1.4	2.3	1.4	0.5	0.6	1.8	1.6	-0.4
Fasting Glucose	1.4	1.6	4.7	0.4	1.1	1.8	2.2	1.7	1.0	0.7	-1.3	1.2	0.5	1.7	1.3	0.9	0.4	1.1	1.4	1.8	0.6
Impedance of leg (right)	1.4	6.8	42.8	3.8	-1.4	-0.5	-1.8	-1.4	-0.7	-2.6	1.7	-2.9	-1.7	-1.9	-3.5	-2.1	-2.6	-0.6	-1.1	-6.5	-2.8
Trunk fat percentage	1.4	5.7	20.1	2.9	-1.6	-0.9	-0.3	-1.4	-0.9	-2.8	1.6	-2.7	-2.9	-1.7	-2.5	-1.6	-3.9	-1.0	-1.5	-4.5	-3.4
Impedance of leg (left)	1.4	7.0	41.2	3.6	-2.0	-0.5	-1.2	-1.4	-0.3	-3.5	1.6	-2.7	-2.6	-1.8	-3.2	-1.8	-3.3	-1.2	-0.9	-6.4	-2.4
Impedance of arm (right)	1.4	6.5	34.7	4.5	-0.7	-0.6	-0.7	-0.6	0.3	-2.3	-0.3	-1.2	-1.9	-2.3	-2.3	-0.6	-3.5	-0.1	-0.9	-5.9	-5.1
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	4.4	-1.4	-0.9	-0.5	-0.3	-1.2	0.7	-2.1	0.2	-0.5	-1.9	-1.8	-0.9	0.3	-2.1	-1.9	-1.5	-1.7	-1.6
Number of full sisters	1.4	1.7	5.1	-2.0	-1.0	-1.5	-1.7	-0.7	-2.3	0.4	1.8	-2.1	0.0	-0.4	-0.5	-1.6	1.5	-0.2	-0.6	-0.6	-0.4
Commuting to job workplace: Car/motor vehicle	1.4	1.6	5.0	0.6	-1.9	0.1	0.0	-1.1	-0.4	-1.9	1.5	-0.9	-2.2	-0.1	-0.7	-1.2	-1.9	-1.9	-1.4	-0.9	0.4
Illnesses of father: Heart disease	1.4	2.0	8.8	3.0	-1.2	-1.1	-1.0	-1.0	-1.5	-0.7	0.5	-1.1	-1.5	-1.2	-1.8	-1.5	-1.1	-0.6	-1.6	-1.7	-1.0
Loneliness, isolation	1.4	1.9	7.5	0.3	-0.4	0.6	0.5	0.7	1.4	-2.3	-1.6	0.3	-1.3	-1.9	-0.4	0.4	-1.7	-1.9	-0.7	-1.7	-2.7
Medication: Blood pressure	1.4	2.6	4.5	1.8	1.8	0.9	0.8	1.6	1.8	2.0	-2.0	1.5	2.0	1.6	1.7	1.4	1.8	2.1	1.1	1.5	0.7
Unable to work because of sickness or disability	1.4	1.8	6.9	1.2	1.3	0.7	-0.8	1.1	0.3	2.4	0.1	1.8	1.8	0.7	0.6	0.5	2.6	2.0	1.0	0.5	1.5
Impedance of whole body	1.4	7.3	42.4	4.7	-1.1	-0.4	-0.7	-0.8	0.4	-3.4	0.4	-1.9	-2.5	-1.9	-2.6	-1.0	-3.8	-0.8	-0.7	-6.5	-3.8
Supplements: Zinc	1.3	1.4	7.0	-0.5	0.5	0.1	-0.6	-0.5	-2.0	2.0	0.3	-0.4	1.0	1.4	-0.2	-0.5	2.2	1.1	0.1	0.7	2.6
Arm fat percentage (right)	1.3	5.1	10.0	0.9	-2.4	-2.1	-1.7	-2.4	-2.6	-1.4	2.6	-2.9	-2.2	-1.8	-3.2	-2.4	-2.5	-0.9	-2.1	-3.1	-2.0
Trunk fat-free mass	1.3	7.2	18.8	-0.3	2.9	3.9	3.7	4.3	3.5	-0.5	-4.0	1.2	0.1	0.4	3.7	2.6	-0.3	-0.0	1.2	2.3	-4.0
Trunk predicted mass	1.3	7.5	19.9	-0.3	2.9	3.9	3.8	4.5	3.6	-0.5	-4.0	1.3	0.2	0.4	3.8	2.6	-0.3	-0.0	1.2	2.3	-4.1
Birth weight	1.3	2.8	7.5	-0.6	-1.4	0.6	-0.2	0.0	-1.4	-1.7	0.4	-1.6	-2.0	-2.3	-1.2	-2.2	-1.3	-2.7	-2.7	-1.6	-2.3
Medication: Ibuprofen	1.3	1.6	5.2	-0.4	-0.5	-0.3	-0.6	-0.8	0.5	-1.7	0.3	-0.7	-1.5	-2.3	-1.2	0.1	-1.5	-1.7	-1.5	-2.0	-1.7
Ever had hysterectomy (womb removed)	1.2	1.4	10.2	-3.2	0.1	-0.7	-1.4	-1.1	-1.0	-0.5	0.6	-0.3	-0.1	-1.3	-0.5	-0.2	-0.9	-0.7	-0.9	-0.3	-2.2
Maternal smoking around birth	1.2	1.7	6.9	-1.4	-1.5	-0.6	0.3	-1.1	-0.5	-2.2	0.7	-1.2	-1.8	-0.2	-1.0	-1.0	-2.6	-1.6	-0.6	-0.5	-1.4
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	3.9	-0.3	1.9	1.5	2.0	1.8	0.8	2.0	-0.5	0.0	1.8	0.4	0.6	0.5	1.8	1.7	0.9	0.9	0.5
Impedance of arm (left)	1.2	5.7	26.6	4.6	-0.1	-0.1	-0.1	-0.0	1.0	-2.5	-0.8	-0.9	-2.0	-1.6	-1.8	-0.2	-3.7	-0.1	-0.3	-5.2	-4.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	5.2	0.8	-0.5	1.1	0.3	0.8	-0.7	-1.5	0.8	-1.7	-2.1	-1.4	-1.7	-2.3	-1.0	-1.6	-1.3	-1.7	-1.4
Loud music exposure frequency	1.2	1.3	3.4	-0.5	-1.4	-1.1	-1.3	-0.9	-1.0	-0.5	1.8	-1.0	-1.4	-1.0	-1.2	-1.2	-0.8	-1.0	-1.4	-0.7	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	3.4	1.8	-0.6	-0.7	-1.6	-0.5	-1.8	-0.6	0.9	-1.1	-0.9	-1.7	-1.8	-1.8	-0.0	-1.1	-1.6	-1.6	-0.3
Leg fat-free mass (right)	1.2	6.3	18.2	-0.3	2.2	2.8	3.5	3.4	3.4	-1.0	-3.8	1.6	-0.7	0.3	3.5	2.6	-1.4	-0.1	1.1	2.2	-4.3
Osteoporosis (self-reported)	1.2	1.4	4.1	-1.2	-0.6	-1.1	-0.8	-0.8	-1.7	0.4	2.0	-1.4	-0.4	-1.2	-1.2	-1.5	1.0	-1.1	-1.8	-0.4	1.3
Osteoarthritis (self-reported)	1.2	1.5	4.2	0.3	1.3	0.2	-0.2	0.1	-0.8	2.0	0.1	1.0	1.6	1.9	0.8	0.4	1.5	1.8	1.2	1.8	1.5
Leg predicted mass (right)	1.2	6.3	18.1	-0.3	2.2	2.8	3.6	3.5	3.4	-0.9	-3.8	1.6	-0.6	0.3	3.6	2.6	-1.3	-0.1	1.1	2.3	-4.3
Mother’s age at death	1.2	1.5	8.0	0.4	0.0	-2.8	-1.3	-2.5	-1.8	0.3	0.4	-0.9	0.4	-0.7	-0.7	0.3	-0.1	0.2	-0.9	-1.8	1.1
Medication: Lisinopril	1.2	1.5	4.0	0.8	2.0	1.6	1.4	1.2	1.1	1.9	-0.2	0.9	1.6	0.9	0.8	0.4	0.9	1.6	0.7	1.7	-0.4
Diastolic blood pressure, automated reading	1.2	3.8	12.6	-2.5	2.2	0.7	0.4	1.3	0.2	3.3	-1.1	2.3	3.5	0.4	1.8	1.8	2.4	2.5	1.0	2.0	0.5
Pain all over the body in last month	1.1	1.2	3.1	1.1	1.3	1.2	0.8	0.7	1.6	0.9	-0.9	1.1	0.4	1.5	0.7	1.0	0.1	1.8	1.2	0.7	1.1
Diabetes (self-reported)	1.1	1.8	8.2	-2.9	1.3	1.0	1.0	0.9	0.5	0.9	-0.6	0.8	0.2	1.5	1.5	0.7	1.4	1.6	2.2	1.3	0.8
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	21.5	2.4	0.5	1.2	1.5	1.9	3.2	-1.4	-2.5	1.1	0.1	-1.4	0.5	1.6	-1.6	0.3	0.3	-2.3	-4.6
Whole body fat-free mass	1.1	6.5	16.9	-0.3	2.5	3.5	3.6	4.0	3.4	-0.9	-3.8	1.1	-0.3	0.2	3.5	2.4	-0.8	-0.3	1.0	2.1	-4.1
Arm fat percentage (left)	1.1	4.4	8.8	0.8	-2.2	-2.1	-1.7	-2.4	-2.3	-1.4	2.5	-2.7	-2.3	-1.2	-3.0	-2.2	-2.5	-0.7	-1.7	-2.6	-1.5
Diabetes diagnosed by doctor	1.1	1.8	5.4	-2.3	1.6	0.9	1.2	1.0	0.2	1.2	-0.7	0.7	0.3	1.6	1.7	0.7	1.5	1.9	2.1	1.4	0.8
Breast cancer (self-reported)	1.1	1.3	3.2	0.6	1.5	0.8	1.3	1.0	1.1	1.8	-0.8	0.6	1.3	1.0	1.4	0.7	1.4	1.6	1.1	1.2	0.4
Whole body water mass	1.1	6.4	17.0	-0.4	2.5	3.5	3.6	4.0	3.4	-0.8	-3.8	1.1	-0.2	0.2	3.5	2.4	-0.7	-0.2	1.0	2.2	-4.1
Ever taken oral contraceptive pill	1.1	1.2	4.1	-2.0	0.5	0.1	-0.1	1.1	0.5	1.2	-0.9	1.5	1.7	0.8	0.9	1.1	1.5	1.2	1.3	0.5	-0.1
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.3	1.5	1.7	1.5	1.2	1.8	1.2	1.2	-1.0	-0.7	1.4	0.3	0.6	0.0	1.1	1.2	0.7	0.5	-0.5
Bipolar Disorder (2018)	1.0	1.6	5.1	-0.5	1.1	1.5	1.6	2.1	1.9	0.9	-2.3	0.9	0.5	-0.6	1.1	1.8	0.2	0.6	-0.1	0.6	-1.2
Lung FEV1/FVC ratio	1.0	5.0	13.0	0.5	-3.5	-3.0	-1.8	-3.6	-1.5	-2.4	2.6	-1.5	-2.5	-1.1	-3.0	-1.1	-2.9	-1.4	-1.4	-2.6	0.3
Diabetes (mother)	1.0	1.3	3.4	1.9	0.2	0.7	1.6	1.0	1.8	-0.9	-1.1	0.7	-0.2	1.4	1.2	1.1	-0.7	0.8	1.7	0.7	0.2
Leg fat-free mass (left)	1.0	5.1	21.6	0.0	2.2	2.6	3.0	3.2	2.9	-0.9	-3.4	1.0	-0.6	0.0	2.9	2.1	-1.4	-0.0	0.8	1.6	-4.7
High blood pressure (mother)	1.0	1.4	11.9	3.5	-0.6	-1.4	-1.3	-1.0	-0.6	-0.4	0.6	-0.4	-0.6	-1.1	-1.2	-0.7	-0.2	-0.4	-1.3	-1.4	-0.4
Leg predicted mass (left)	1.0	5.3	21.4	-0.1	2.2	2.7	3.1	3.2	3.0	-0.9	-3.4	1.1	-0.6	0.1	3.0	2.1	-1.4	-0.0	0.8	1.7	-4.6
Happiness	1.0	1.2	5.3	0.9	1.4	1.2	1.3	0.8	1.0	-1.1	-0.8	0.9	-0.3	1.8	1.3	0.5	-0.7	0.3	2.3	0.5	-0.2
Illnesses of mother	1.0	1.2	8.3	-2.9	0.5	1.7	1.2	1.3	0.9	-0.4	-1.4	0.9	0.1	-0.1	1.1	0.6	0.2	-0.7	0.3	0.8	-0.8
Exposure to tobacco smoke at home	1.0	1.2	4.1	-0.1	-1.0	0.4	0.4	0.2	1.8	-1.9	-1.2	1.4	-0.9	0.2	0.9	1.6	-2.0	-0.9	0.5	-0.4	-0.3
Wheeze or whistling in the chest in last year	1.0	1.8	5.8	0.6	-0.9	0.7	-0.1	0.5	-0.3	-1.8	0.8	-2.0	-2.4	-1.2	-1.9	-2.0	-1.8	-1.3	-0.8	-1.3	-1.0
Illnesses of siblings: Diabetes	1.0	1.2	5.0	-1.2	0.5	0.4	0.5	-0.1	-0.7	0.5	0.7	0.2	1.1	2.2	1.1	0.3	1.2	0.9	2.0	1.3	1.7
Alcohol drinker status: Never	1.0	1.2	3.4	-0.9	1.0	0.2	0.3	0.6	-1.3	1.7	0.8	-0.9	1.1	1.6	-0.0	-0.7	1.8	1.2	0.7	0.4	1.8
Coronary Artery Disease (CAD)	0.9	1.0	8.8	0.0	-0.5	0.3	-0.7	-0.3	-1.3	0.5	1.7	-0.6	0.2	1.3	-0.3	-0.7	0.9	0.2	0.2	0.6	3.0
Angina	0.9	1.2	7.0	2.6	1.0	0.9	1.3	0.7	-0.9	1.0	0.9	-1.1	0.7	1.1	-0.1	-0.8	1.4	0.6	0.4	0.4	1.6
Diabetes (father)	0.9	1.1	4.0	-1.1	-0.6	0.4	0.4	0.5	0.2	-2.0	-0.9	-0.1	-1.8	-1.1	-0.4	-0.1	-1.6	-1.2	-0.2	-0.2	-1.9
Qualifications: CSEs or equivalent	0.9	1.2	2.7	-1.3	-1.3	0.3	0.2	0.4	1.0	-1.4	-0.3	0.4	-1.6	-1.4	-0.5	-0.4	-1.6	-1.5	-1.2	-0.7	-1.5
Multivitamins +/- minerals	0.9	1.2	5.2	0.1	1.3	-0.2	-0.3	0.4	-0.5	2.0	-1.0	0.1	2.3	0.3	0.5	0.7	1.7	1.9	1.1	0.7	-0.3
Trunk fat mass	0.9	4.1	16.9	2.6	-0.8	0.1	0.6	-0.1	0.1	-2.6	0.4	-2.1	-2.5	-1.4	-1.4	-0.8	-3.5	-0.8	-1.1	-3.5	-4.1
Hair/balding pattern: Pattern 2	0.9	1.2	3.9	-0.4	0.4	1.6	1.2	1.4	0.8	0.8	-0.3	0.3	0.3	2.0	0.2	0.3	-0.7	1.8	1.7	1.6	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	17.0	2.1	1.2	1.0	1.4	2.3	3.0	-0.6	-2.2	0.8	0.5	-0.7	0.9	1.3	-0.9	0.9	0.8	-1.5	-4.1
Angina (self-reported)	0.9	1.2	7.7	2.8	0.8	0.8	1.3	0.6	-1.0	0.7	1.0	-1.2	0.5	1.0	-0.2	-0.9	1.2	0.3	0.3	0.3	1.6
Medication: Allopurinol	0.9	1.3	3.8	-0.2	0.4	0.8	0.4	0.8	2.0	0.7	-0.5	1.5	0.9	1.4	1.2	1.6	-0.1	1.1	1.8	1.8	0.4
Chest pain or discomfort	0.9	1.3	4.5	1.8	1.5	2.0	1.4	2.1	0.3	0.8	0.6	-0.5	0.6	0.7	0.2	-1.0	1.7	0.7	0.9	0.6	0.4
Medication: Aspirin	0.9	1.1	4.5	1.0	0.4	0.6	1.1	0.1	0.1	1.0	-0.3	0.7	0.9	1.7	0.7	0.6	1.2	1.6	1.4	0.9	2.1
Medication for cholesterol	0.9	1.4	2.6	-0.8	-1.5	-1.0	-0.6	-1.4	-1.3	-1.3	1.2	-1.6	-1.2	-1.3	-1.3	-1.1	-0.9	-1.6	-1.1	-1.2	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	4.3	-0.7	-0.5	0.8	0.3	0.5	-0.9	-0.7	1.0	-1.1	-1.2	-1.0	-1.7	-2.1	-0.0	-0.5	-0.7	-1.5	-0.5
Mineral and other dietary supplements	0.9	1.3	3.2	-0.3	1.4	1.4	1.3	1.8	1.4	0.1	-0.3	0.2	0.6	1.6	1.4	1.1	0.6	0.2	1.3	1.3	1.5
Medication: Aspirin	0.9	1.2	4.6	1.2	0.3	0.4	0.9	0.1	-0.1	1.0	-0.3	0.6	0.9	1.8	0.6	0.5	1.2	1.8	1.5	0.9	2.1
Basal metabolic rate	0.9	5.0	19.9	-0.0	2.0	3.0	3.1	3.4	2.9	-1.2	-3.1	0.6	-0.7	-0.0	2.7	1.8	-1.3	-0.4	0.7	1.3	-4.5
Age started oral contraceptive pill	0.9	1.1	3.5	1.2	0.4	-1.8	-1.6	-1.0	-1.1	1.2	0.9	-0.6	1.2	0.6	-0.2	0.0	1.1	0.8	0.4	0.3	1.9
Type 2 Diabetes (T2D) (2018)	0.8	1.5	3.3	-1.8	1.4	0.7	0.7	0.7	1.1	0.6	-1.7	1.3	0.2	1.0	1.6	1.6	0.2	1.8	1.8	0.8	-0.8
Hearing difficulty/problems: Yes	0.8	1.3	5.0	1.0	1.4	0.4	-0.4	0.5	-0.2	2.0	0.2	-1.2	2.2	-0.1	0.1	0.3	2.1	0.8	-0.3	0.5	1.7
Severe depression (siblings)	0.8	0.9	4.4	-0.6	0.1	-1.0	-2.1	-0.7	-1.4	1.0	0.6	-0.6	0.7	0.3	-0.6	-0.7	1.7	0.2	-0.1	-0.1	1.2
Hand grip strength (right)	0.8	2.1	7.6	0.6	0.5	1.0	0.9	1.8	2.6	-1.9	-2.5	0.8	-0.9	-0.4	1.1	1.6	-1.3	-1.2	0.1	-0.3	-2.8
Average weekly fortified wine intake	0.8	0.9	4.4	1.1	0.4	0.6	0.6	0.2	1.4	0.7	-1.3	2.1	1.1	-0.0	0.8	1.6	0.3	0.4	-0.0	0.4	1.1
Neuroticism score	0.8	1.6	6.3	0.5	-0.1	2.5	1.9	1.6	0.8	-2.1	-1.0	0.4	-1.3	0.1	-0.1	-0.5	-1.4	-0.9	0.9	-0.7	-2.0
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	3.4	0.4	0.8	1.3	1.3	1.5	1.8	-0.7	-1.2	1.2	-0.5	0.7	0.7	1.2	-1.1	0.6	1.8	0.4	-1.2
Length of working week for main job	0.8	0.9	5.6	-2.4	0.4	0.3	0.0	0.8	0.7	-0.3	-0.7	0.4	-1.0	-1.1	0.3	-0.0	-0.5	-1.1	-0.8	0.8	-1.8
Birth weight of first child	0.8	1.4	6.6	-0.7	-0.4	1.1	1.1	1.1	-0.3	-2.6	-0.1	-0.4	-1.7	-0.1	-0.5	-0.6	-1.8	-2.1	-0.2	-1.1	-1.1
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	3.9	0.6	1.5	-0.8	0.1	0.1	0.8	0.6	-1.8	1.8	1.2	1.2	1.5	2.0	0.2	1.0	1.0	0.6	0.0
Arm fat-free mass (right)	0.8	4.1	11.2	-0.5	1.8	3.1	3.0	3.3	2.8	-1.4	-2.6	0.2	-0.7	0.4	2.8	1.6	-0.7	-0.9	0.8	1.8	-2.7
Comparative body size at age 10	0.8	2.3	9.0	-2.0	-1.2	-2.9	-1.3	-3.0	-1.4	-1.1	1.0	-0.1	-1.2	-0.4	-1.0	-0.9	-1.2	-2.1	-1.3	0.7	0.8
Age at first live birth	0.8	1.4	2.6	0.9	1.5	1.1	1.0	1.2	1.3	1.6	-0.8	1.0	1.4	0.9	1.1	1.1	1.5	1.5	0.9	0.9	0.8
Shortness of breath walking on level ground	0.8	1.0	3.6	0.9	0.8	1.5	1.8	1.0	1.9	-0.7	-1.0	0.4	-0.4	0.7	1.0	0.6	-0.7	0.0	0.7	0.4	-0.9
Whole body fat mass	0.8	3.5	9.6	1.8	-1.3	-0.5	-0.0	-0.8	-0.7	-2.3	1.3	-2.6	-2.5	-1.1	-1.8	-1.4	-3.1	-0.9	-1.2	-3.0	-3.1
Arm predicted mass (right)	0.8	4.1	10.4	-0.6	1.8	3.0	3.0	3.2	2.9	-1.3	-2.7	0.4	-0.7	0.5	2.8	1.7	-0.8	-0.8	0.8	1.9	-2.6
Mood swings	0.8	1.4	10.8	0.1	-0.0	1.2	1.1	1.6	0.7	-1.3	-0.8	1.0	-1.0	-1.4	-0.5	-0.1	-0.9	-0.6	0.3	-1.1	-3.3
Commuting to job workplace: Walk	0.8	0.8	3.3	0.2	1.8	-0.3	-0.4	0.2	-0.6	1.8	-0.7	0.9	1.8	0.4	0.0	0.4	0.5	1.5	0.5	0.5	-0.2
Medication: Gliclazide	0.8	0.9	3.3	-0.2	0.9	1.7	1.8	0.9	1.2	-0.6	-0.6	0.4	-1.0	1.0	0.9	0.7	-0.8	0.1	1.3	0.6	-0.4
Arm fat-free mass (left)	0.8	3.9	11.8	-0.6	1.7	3.0	3.0	3.2	2.5	-1.4	-2.4	0.3	-0.6	0.1	2.6	1.4	-0.9	-1.0	0.6	1.3	-3.4
Ovarian Cancer	0.7	0.9	2.6	-1.6	0.4	0.9	0.2	1.1	0.8	1.6	-0.3	-0.6	0.9	-0.2	0.8	0.3	1.1	1.6	0.7	0.7	-1.4
Ulcerative Colitis	0.7	1.1	3.2	-0.7	1.5	1.5	1.3	1.0	0.2	1.8	0.2	-0.2	1.0	0.6	0.9	-0.3	1.5	1.4	0.4	1.3	0.1
Allergy or Eczema	0.7	1.9	7.3	0.9	1.4	1.0	1.4	0.8	0.5	1.2	0.3	1.1	1.5	2.0	1.3	1.1	1.1	1.4	1.9	1.5	2.7
Hand grip strength (left)	0.7	1.9	5.7	1.2	-0.2	0.3	-0.1	1.0	2.3	-1.8	-2.1	1.0	-0.9	-1.4	0.6	1.7	-1.2	-1.5	-0.8	-1.0	-2.4
Father’s age at death	0.7	1.0	3.5	0.3	1.7	1.9	1.3	1.8	0.7	0.8	-0.6	-0.9	0.7	-0.2	0.2	-0.0	1.5	-0.1	-0.1	0.2	1.2
Hair/balding pattern: Pattern 3	0.7	1.1	3.1	0.4	1.7	0.6	0.5	0.5	1.6	0.8	-1.8	1.2	1.0	0.9	1.1	1.2	0.7	0.9	0.9	1.0	0.8
Asthma	0.7	1.4	3.9	0.7	-0.9	-1.0	-1.1	-0.7	-1.2	-0.8	1.1	-1.5	-1.2	-1.2	-2.0	-1.6	-0.7	-1.1	-1.5	-1.6	0.2
Prospective memory result	0.7	0.9	3.3	-0.0	0.6	0.1	0.3	0.4	0.5	1.3	-0.6	0.8	1.6	0.5	0.8	1.4	1.2	1.0	0.7	0.4	1.8
Tense / ‘highly strung’	0.7	1.2	6.0	1.1	0.8	1.8	1.1	1.1	-0.2	0.7	0.1	0.3	0.6	1.8	0.4	-0.5	0.9	0.7	0.8	0.7	2.4
Gout (self-reported)	0.7	0.9	2.7	0.6	0.1	0.4	0.2	0.6	1.3	0.8	0.1	1.2	1.0	1.4	1.0	1.3	-0.1	1.3	1.7	1.2	-0.0
Medication: Omeprazole	0.7	0.8	2.7	0.6	-0.0	0.1	-0.8	0.4	-0.5	0.2	1.0	-1.4	-0.3	1.1	-1.2	-1.4	0.6	1.1	0.9	-0.7	1.6
Leg fat mass (right)	0.7	2.7	6.3	0.9	-1.6	-1.0	-0.8	-1.3	-1.2	-1.7	1.7	-2.5	-2.0	-0.9	-1.8	-1.5	-2.4	-0.8	-1.3	-2.4	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	4.9	-2.2	-1.2	-0.4	-0.8	-0.1	-1.4	0.4	0.5	-1.0	-0.1	-0.1	-0.7	-1.1	0.2	0.1	-0.2	0.6	-0.5
Eye problems/disorders: Cataract	0.7	0.8	3.4	1.4	0.1	-1.4	-0.7	-1.4	-0.6	0.7	0.1	0.9	1.0	-0.4	-0.7	0.4	0.3	0.4	-0.6	-0.7	1.9
Asthma (self-reported)	0.7	1.5	4.2	0.4	-1.0	-1.0	-1.2	-0.7	-1.2	-0.8	1.0	-1.6	-1.3	-1.2	-2.1	-1.6	-0.7	-1.1	-1.5	-1.5	0.1
Smoking status: Current	0.7	1.1	3.5	-1.4	0.0	-0.9	-1.0	-0.7	-0.8	-1.6	-0.1	-0.7	-1.2	-1.0	-1.0	-1.0	-0.5	-1.6	-0.7	-1.9	-0.8
Pain experienced in last month	0.7	1.2	2.9	1.1	1.3	1.1	0.6	0.6	0.6	0.8	-0.9	1.4	1.7	1.3	0.7	1.1	0.6	1.1	1.5	0.7	1.3
Leg fat mass (left)	0.7	2.8	6.7	0.8	-1.8	-1.1	-0.7	-1.4	-1.2	-2.0	1.8	-2.4	-2.2	-0.8	-1.7	-1.4	-2.6	-1.0	-1.3	-2.2	-1.9
Arm predicted mass (left)	0.7	3.5	10.2	-0.3	1.7	3.0	2.9	3.2	2.4	-1.2	-2.3	0.2	-0.5	0.1	2.5	1.3	-0.6	-0.8	0.6	1.4	-2.9
Depressed Affect (Nagel 2018)	0.6	1.3	5.8	-0.4	0.2	1.5	1.6	0.7	1.1	-1.6	-0.8	1.3	-1.1	-0.7	0.3	0.5	-1.9	-1.0	0.0	-0.3	-2.4
Neuroticism (Nagel 2018)	0.6	1.3	5.0	0.7	-0.2	1.4	1.1	0.3	0.3	-2.1	-0.6	0.6	-1.5	-0.6	-0.5	-0.3	-2.2	-1.3	-0.1	-0.8	-2.1
Ulcerative Colitis (UC)	0.6	1.1	3.9	-0.3	0.9	1.3	0.6	1.0	-0.5	2.0	0.7	-1.6	0.9	-0.6	0.1	-1.2	1.8	1.2	-0.4	0.9	0.1
Verbal and Numeric Reasoning (VNR)	0.6	1.4	4.1	-2.0	0.5	0.6	0.5	0.9	0.5	1.4	-1.3	1.0	1.5	0.4	0.9	1.4	1.9	1.0	0.8	1.4	1.6
Bipolar Disorder (2011)	0.6	0.6	4.8	-0.1	-0.5	-0.9	0.0	-0.4	-0.6	0.3	-0.2	-0.5	0.2	-2.2	-0.6	0.6	-0.2	-0.8	-1.3	-0.4	-0.8
Mean Putamen Volume	0.6	0.7	3.6	0.9	0.4	-0.8	-0.6	-0.3	-1.9	0.4	0.5	-1.6	-0.3	0.3	-0.6	-1.5	0.3	0.5	-0.1	-0.0	0.3
HDL Cholesterol	0.6	1.0	2.9	-0.3	1.6	1.3	0.6	0.9	-0.1	1.1	-0.1	-0.1	1.4	1.0	0.7	0.8	1.3	0.7	0.9	1.2	1.7
Lupus	0.6	0.9	3.3	-0.5	-0.4	-0.3	-0.9	-0.1	-1.3	1.4	0.8	-0.6	1.5	0.2	-0.9	-0.6	1.8	1.0	0.4	-0.1	1.3
Primary Biliary Cirrhosis	0.6	0.8	2.3	0.1	1.5	0.4	-0.5	0.4	-1.1	1.5	0.6	-0.5	1.3	1.2	0.3	-0.2	1.3	1.1	0.7	0.6	0.7
Respiratory disease	0.6	1.2	3.2	0.7	-0.8	-0.1	-0.0	-0.2	0.0	-1.5	0.2	-0.9	-1.7	-1.7	-1.2	-0.7	-1.5	-1.8	-1.6	-1.3	-0.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.8	0.9	0.5	-1.7	-0.8	-1.5	-1.0	1.0	0.9	0.1	0.6	0.3	-0.5	0.3	0.1	0.9	0.1	0.0	1.5
Current tobacco smoking	0.6	1.0	3.9	-2.0	0.4	-0.8	-0.9	-0.4	-0.8	-1.5	-0.2	-0.7	-0.9	-0.8	-0.8	-0.9	-0.4	-1.6	-0.5	-1.6	-0.7
Fed-up feelings	0.6	1.1	4.2	0.1	0.6	2.0	1.9	1.7	1.2	-0.7	-0.7	0.8	-0.8	-0.1	0.5	0.1	-0.9	-0.2	0.5	0.3	-1.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.9	-1.5	0.4	-0.4	-0.6	-0.1	-1.5	0.7	0.4	-0.7	0.6	-1.7	-0.9	0.1	0.6	0.0	-1.2	-0.7	0.2
Had menopause	0.6	0.8	5.4	2.1	1.1	0.2	0.6	-0.0	0.0	0.5	0.5	-0.4	1.0	0.9	0.3	0.0	0.7	0.1	0.2	0.2	2.3
Medication: Ramipril	0.6	0.8	2.7	0.4	0.1	0.2	0.6	0.8	1.2	0.5	-1.7	1.4	0.9	1.1	1.1	1.0	0.5	0.6	0.9	0.8	0.3
Illnesses of siblings	0.6	0.9	2.3	-0.2	-1.1	-1.1	-0.8	-0.9	0.1	-1.3	-1.2	0.3	-1.0	-1.0	0.0	0.6	-1.2	-1.5	-1.0	-0.8	-1.0
Falls in the last year	0.6	0.8	3.3	-1.1	0.6	0.1	-0.8	0.7	-0.2	1.2	-0.9	1.1	1.5	0.6	0.8	0.8	1.8	1.0	0.6	-0.1	0.1
Pulse rate	0.6	1.0	3.2	-1.4	1.2	0.7	1.0	1.4	-0.1	0.5	0.1	-0.5	-0.0	0.8	1.0	0.2	1.2	0.2	0.7	1.8	1.7
Mouth/teeth dental problems: Dentures	0.6	1.1	3.1	-1.7	-0.1	1.1	0.9	0.7	1.2	-0.8	-0.3	0.7	-0.6	1.8	1.3	1.0	-0.8	0.2	1.3	1.3	0.9
Hair/balding pattern: Pattern 4	0.6	1.5	5.5	0.7	-0.8	-1.9	-0.3	-1.5	-2.4	-0.1	1.6	-1.5	-1.0	-1.4	-0.9	-1.2	-0.2	-1.2	-1.8	-0.4	0.5
Exposure to tobacco smoke outside home	0.6	0.8	3.1	0.9	-0.4	-1.3	-1.2	-1.8	-0.1	-0.7	-0.0	0.7	0.5	-1.1	-0.5	0.9	-1.1	-0.7	-0.8	-1.1	-0.8
Age at last live birth	0.6	0.9	1.9	0.0	0.9	1.2	1.2	0.9	0.9	0.9	-0.4	1.3	1.0	0.5	1.1	0.9	1.4	1.1	0.9	0.5	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	3.6	-1.9	-0.6	-1.5	-1.4	-1.5	-0.2	-0.9	0.2	-0.1	-0.8	-0.2	-0.6	-0.3	-0.5	-0.8	-0.1	-0.3	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.8	2.7	-0.8	-0.0	0.8	0.8	0.6	-0.6	-1.3	0.3	-1.4	-0.7	-1.0	-0.8	-0.9	-0.2	-1.0	-0.5	-1.6	-0.6
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.7	-0.4	1.1	-0.5	-0.0	-0.0	-0.1	0.7	-1.2	1.6	0.7	-0.7	1.3	1.6	0.3	0.3	-0.0	0.5	-0.6
Arm fat mass (left)	0.6	2.4	6.7	0.6	-1.3	-0.7	-0.3	-0.9	-1.0	-1.7	1.2	-2.1	-2.1	-1.3	-1.6	-1.3	-2.5	-1.1	-1.4	-1.9	-2.6
Illnesses of father: High blood pressure	0.6	0.8	2.0	1.2	0.4	1.3	0.5	1.4	0.9	0.5	-1.1	1.0	0.7	0.2	1.3	0.7	0.6	0.6	0.4	0.9	-1.0
Risk taking	0.6	0.8	4.5	-0.1	-1.1	-1.2	-0.6	-1.4	0.4	-1.1	-0.3	-0.1	-1.3	0.2	-1.1	0.2	-2.1	-0.1	0.3	-0.9	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	3.2	0.9	-0.1	0.1	-0.3	0.4	-0.3	-0.5	0.9	-1.8	-0.7	0.7	-1.4	-1.4	0.0	0.5	0.4	-1.4	1.2
Body Mass Index (BMI) (2010)	0.5	0.7	2.4	0.4	-0.1	-1.1	-0.5	-0.8	0.5	1.1	-0.9	1.5	1.6	-0.4	0.6	1.4	0.7	0.5	0.1	0.5	0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	4.8	-2.2	-0.2	-0.4	0.9	0.2	-0.8	0.9	0.4	-0.4	0.5	-0.3	0.9	0.3	0.9	0.0	0.1	0.9	-0.5
Systolic Blood Pressure	0.5	2.5	8.2	2.8	1.8	1.4	0.9	1.1	0.4	2.9	-0.4	1.2	2.4	1.2	0.6	0.1	2.0	2.5	0.7	1.0	0.7
Neuroticism	0.5	1.2	5.6	0.4	0.3	2.4	1.8	1.5	0.6	-1.8	-1.1	0.5	-0.9	0.1	-0.4	-0.2	-1.2	-0.6	0.8	-0.8	-1.4
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	5.2	-2.3	0.2	-0.2	-0.0	-0.3	0.7	0.3	-0.9	0.8	-0.1	0.2	0.6	0.7	0.1	0.6	0.7	0.4	-0.3
Medication: Co-codamol	0.5	0.6	2.6	1.6	0.2	0.0	-0.3	0.5	-1.0	1.2	0.7	-0.4	0.2	0.5	-0.2	-1.3	1.0	0.9	0.1	0.5	0.3
Pack years adult smoking proportion	0.5	0.7	2.8	-0.5	-0.2	-1.4	-1.7	-1.0	-0.6	-0.3	0.3	-0.7	-1.0	-1.0	-0.9	-0.6	-0.1	-0.8	-0.9	-0.4	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.2	-0.5	-1.3	-1.2	-1.1	-1.1	-1.7	1.8	1.4	-0.9	0.4	0.1	-0.8	-1.0	1.2	1.3	-0.4	0.2	0.9
Serious illness, injury or assault to yourself	0.5	0.6	2.1	0.0	-0.5	-0.9	-1.4	-0.7	-0.2	-0.5	-0.3	0.7	-0.7	-0.7	-0.1	0.0	-0.5	-1.0	-1.3	-1.2	-0.3
Stomach or abdominal pain in last month	0.5	0.6	2.0	-0.9	-0.6	1.4	1.1	1.0	0.5	-1.1	-0.0	0.2	-1.1	0.7	0.6	0.1	-0.6	-0.3	1.2	0.8	0.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.6	1.6	-0.3	0.0	-0.6	-0.1	-1.3	0.2	1.5	-0.9	0.1	0.4	-0.8	-1.3	-0.1	0.1	-0.1	-0.1	0.0
Number of incorrect matches in round	0.5	0.8	4.2	-0.3	0.3	0.8	1.3	1.1	-0.3	-0.5	-0.4	0.2	0.0	2.0	1.2	0.1	-0.5	0.3	1.5	1.4	0.5
Heart attack	0.5	0.7	3.5	1.0	0.5	0.5	-0.5	0.3	0.1	0.6	-0.3	0.7	0.6	1.9	0.2	0.2	0.3	1.5	1.4	0.6	0.7
Medication: Simvastatin	0.5	0.7	2.5	0.1	0.7	1.1	1.0	1.6	1.4	-0.1	-1.1	0.4	0.6	-0.2	0.2	1.1	0.9	0.3	0.5	-0.2	1.4
Weight	0.5	2.5	18.4	0.8	0.5	1.5	1.8	1.6	1.5	-1.9	-1.2	-0.9	-1.6	-0.7	0.6	0.5	-2.4	-0.6	-0.2	-0.9	-4.3
Time employed in main current job	0.5	0.6	3.7	0.3	1.9	0.6	0.6	0.8	0.3	1.0	-0.2	-0.4	0.8	0.5	0.6	-0.3	1.2	0.7	0.4	0.3	0.4
Depression (self-reported)	0.5	0.6	3.2	1.8	-0.4	-0.4	-1.1	-0.3	-0.8	0.5	0.2	-0.6	-0.3	-0.5	-1.3	-0.7	-0.1	0.6	-0.2	-0.9	0.3
Medication: Lansoprazole	0.5	0.5	2.5	0.1	-0.4	0.1	0.2	-0.1	0.9	-0.7	-1.1	0.7	-0.3	-1.6	0.2	1.0	-0.5	-0.7	-0.4	-1.0	-0.9
Lung cancer (father)	0.5	0.5	7.1	2.7	-0.2	0.5	-0.1	0.2	-0.1	0.0	-0.1	0.5	0.7	0.6	0.1	-0.1	0.1	0.7	0.4	-0.7	0.1
Arm fat mass (right)	0.5	1.9	5.8	0.5	-1.1	-0.6	-0.1	-0.7	-0.9	-1.4	1.1	-2.0	-1.9	-1.0	-1.3	-1.2	-2.3	-0.8	-1.2	-1.6	-2.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	0.5	-0.3	1.0	1.1	0.2	0.3	-1.0	1.2	-0.9	-1.3	1.1	0.2	-0.7	-1.0	-0.2	0.9	0.7	0.2
Headache pain in last month	0.5	0.8	1.8	-0.8	-0.1	0.7	0.7	0.7	1.3	-1.3	-1.1	1.2	-0.7	-1.0	0.6	0.9	-0.8	-1.2	-0.2	-0.1	-1.2
Glaucoma (self-reported)	0.5	0.5	2.2	0.8	0.3	-0.4	-0.3	-0.3	0.6	0.5	-0.7	0.5	1.1	1.1	0.1	0.6	0.0	1.3	1.5	-0.0	0.9
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.0	-0.1	-0.4	-0.3	-0.4	-0.5	-0.1	-1.0	0.1	-1.3	-0.7	-1.4	-1.0	-0.7	-0.7	-1.1	-1.1	-0.8	0.1
Number of children fathered	0.5	0.6	1.8	-0.8	0.5	0.8	-1.2	0.4	-0.4	0.5	1.2	-0.8	0.4	-0.1	-0.7	-1.2	1.3	-0.5	-0.7	0.2	0.2
Hypertension (Self-reported)	0.5	1.3	3.3	0.5	1.2	1.1	1.4	1.6	1.1	1.8	-1.2	0.8	1.4	0.3	1.0	1.1	1.5	1.5	0.2	0.9	0.1
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	3.2	0.3	0.9	0.4	0.2	0.1	1.1	1.3	-0.1	0.6	1.4	0.2	0.8	0.8	1.8	1.1	1.0	0.5	1.0
Illnesses of father: None of the above (group 1)	0.5	0.7	2.6	-1.1	0.7	0.8	0.9	0.5	0.3	0.1	-0.5	1.0	1.0	0.4	1.2	1.6	0.5	-0.3	0.5	0.2	1.1
Number of self-reported non-cancer illnesses	0.5	0.9	3.2	1.8	0.3	-1.2	-1.1	-0.4	-0.9	1.2	0.5	0.2	1.3	-0.7	-0.9	0.2	1.2	0.8	-0.7	-1.0	1.2
Miserableness	0.5	0.8	2.9	0.1	-0.6	1.2	0.7	0.4	0.3	-1.7	-0.1	1.1	-1.2	-0.5	-0.1	-0.2	-1.3	-1.4	-0.1	-0.8	-1.4
Hearing aid user	0.5	0.6	5.3	2.3	0.1	-0.2	-0.0	-0.1	0.6	0.4	0.1	0.1	0.8	0.6	0.4	0.8	-0.0	0.3	0.0	0.2	1.7
Ever depressed for a whole week	0.5	0.6	2.5	-0.3	-0.5	0.5	-0.7	-0.4	-0.9	-0.3	1.5	-1.3	-1.2	0.5	-0.9	-1.6	-0.2	-0.3	0.2	-0.2	0.5
Heart attack/myocardial infarction (self-reported)	0.5	0.7	3.2	0.9	0.7	0.8	-0.4	0.4	0.2	0.6	-0.5	0.9	0.6	1.8	0.2	0.2	0.3	1.5	1.5	0.7	0.7
Pack years of smoking	0.5	0.8	2.6	-0.2	-0.3	-1.6	-1.6	-1.3	-0.9	-0.2	0.6	-0.8	-0.9	-0.6	-0.7	-0.7	-0.2	-0.7	-0.7	-0.2	1.4
Alzheimer’s Disease (in mother)	0.4	0.5	2.7	0.2	-0.3	-1.2	-0.9	-1.1	-0.6	0.4	0.7	0.5	0.7	0.3	-0.1	0.5	0.0	0.8	0.3	-0.4	1.6
Irritable Bowel Disease (IBD)	0.4	1.0	3.3	-0.7	0.2	1.1	0.4	0.7	-0.6	1.3	1.2	-1.8	0.7	-0.7	-0.5	-1.6	1.8	0.4	-0.7	0.3	0.6
Age at First Birth	0.4	0.5	2.1	-0.1	-0.8	-0.0	-0.8	-0.6	-0.9	-0.7	0.2	-0.5	-0.7	-0.5	-1.2	-0.7	-0.6	-0.5	-1.0	-1.4	-0.4
Crohns Disease (2012)	0.4	0.6	2.4	-1.6	0.1	1.2	1.0	0.7	0.0	-0.7	0.0	0.2	-0.1	1.3	1.0	-0.2	0.2	-0.5	0.7	0.8	0.6
Heel T-Score	0.4	3.0	11.4	2.6	0.8	-0.3	-1.4	0.4	-0.6	3.4	-0.2	1.5	1.9	1.4	0.3	-0.0	2.9	3.1	0.5	0.8	2.5
Waist Hip Ratio (WHR)	0.4	2.0	14.5	3.8	-0.8	-1.3	-1.4	-0.8	-1.0	-0.2	0.4	-0.7	-0.6	-1.3	-1.1	-0.7	-0.5	0.0	-1.7	-2.6	-1.1
Cardiovascular Disease	0.4	1.4	4.5	0.2	1.1	1.1	0.5	1.3	0.8	2.0	-0.7	0.5	1.2	1.2	0.7	0.7	1.9	2.1	1.0	1.3	0.7
Lung FVC	0.4	2.1	5.4	0.5	-1.3	-2.3	-1.3	-1.1	-2.0	1.1	2.0	-1.2	0.7	-1.1	-2.1	-1.9	1.4	0.5	-1.3	-1.9	0.4
Number of treatments/medications taken	0.4	0.7	2.8	0.6	0.9	-0.3	-0.5	0.4	-0.1	1.5	-0.1	0.9	1.7	-0.3	-0.1	0.5	1.4	1.3	0.2	-0.7	0.8
Average weekly spirits intake	0.4	0.4	3.0	-0.4	0.3	-0.4	-0.7	-0.4	0.1	1.3	0.5	-0.0	1.7	-0.1	-0.3	0.5	0.7	0.9	0.1	0.5	-0.4
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.3	-0.1	-0.3	0.6	0.5	0.4	0.6	-1.3	-0.9	0.4	-1.0	-0.3	0.1	0.5	-1.5	-0.2	0.7	-0.6	-1.5
Vitamin and mineral supplements	0.4	0.5	1.8	-1.0	0.2	1.1	0.7	0.5	1.4	-0.9	0.1	0.4	-1.3	0.4	0.7	-0.0	-0.0	-0.9	0.1	0.5	0.8
Taking other prescription medications	0.4	0.6	2.9	0.1	0.5	-0.8	-0.9	-0.5	-0.7	0.1	1.4	-1.1	-0.1	0.2	-1.2	-0.8	-0.1	0.2	0.1	-0.5	1.7
Body mass index (BMI)	0.4	1.6	4.9	-1.5	-1.5	-1.5	-1.1	-1.8	-1.9	-0.0	2.2	-1.5	-0.8	-0.4	-1.5	-1.5	-0.6	-0.4	-1.1	0.2	0.7
Alcohol usually taken with meals	0.4	0.6	4.2	0.4	0.5	0.3	-0.3	0.1	0.0	0.2	0.6	-0.3	-0.4	2.1	-0.2	-0.1	0.1	0.7	1.1	0.8	1.6
Nervous feelings	0.4	0.7	3.4	1.5	0.1	1.0	0.4	-0.0	0.2	-1.9	-0.8	0.3	-0.8	-0.3	-0.1	0.1	-1.4	-1.4	-0.4	-0.7	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.6	0.9	-0.3	0.9	0.1	0.5	-0.1	-1.2	0.1	-1.0	-1.2	-1.0	-0.9	-0.6	-0.7	-0.8	-0.6	-1.3	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	4.1	-0.4	-0.4	-0.4	-0.7	-0.3	-1.6	2.0	1.0	-0.4	1.2	0.4	-0.6	-0.6	1.6	1.6	0.3	0.6	1.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.2	-1.1	0.1	-0.3	-1.5	-0.9	-1.0	-0.5	1.0	0.2	-0.6	0.8	-0.2	-0.7	-0.4	-0.3	0.4	-0.0	0.8
Mouth/teeth dental problems	0.4	0.6	2.9	-0.5	0.7	-0.1	0.3	0.5	-1.4	1.7	-0.4	-0.2	1.0	0.2	0.3	-0.2	1.3	1.1	-0.2	0.8	-0.1
Fluid intelligence score	0.4	0.8	5.7	-2.4	-0.2	-1.0	-0.5	-0.9	-0.1	0.4	-0.8	0.4	0.7	0.1	0.3	1.0	0.8	-0.1	0.2	0.8	1.8
Pulse wave Arterial Stiffness index	0.4	0.4	2.2	1.5	0.9	0.5	0.2	0.2	-0.0	-0.3	0.6	-1.3	-0.4	0.8	-0.3	-0.3	-0.4	-0.1	0.2	-0.8	0.5
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	4.0	1.0	1.0	-0.1	-0.3	0.7	-0.3	1.4	0.0	-0.6	0.7	0.2	-0.3	-0.7	2.0	1.2	0.1	-0.3	1.3
High blood pressure (siblings)	0.4	0.6	3.0	0.2	1.1	0.9	1.7	1.0	0.1	0.9	0.2	0.2	1.1	0.7	0.5	-0.2	0.7	1.0	0.6	0.9	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.9	1.4	-0.3	-0.8	-0.6	-0.5	-1.2	0.6	0.9	0.0	0.5	0.0	-0.7	-0.5	0.1	0.5	-0.1	0.2	0.8
Pulse wave peak to peak time	0.4	0.4	1.7	-0.9	-0.5	-0.2	0.1	0.1	0.3	0.3	-1.1	1.3	0.4	-0.8	0.6	0.6	0.2	0.2	-0.1	0.6	-1.3
Qualifications: College or University degree	0.4	1.2	4.3	0.4	1.5	2.0	0.9	2.1	0.2	1.5	-0.9	0.6	1.1	0.2	0.6	0.1	1.8	0.9	0.6	1.0	-0.1
Medication: Blood pressure	0.4	0.7	1.9	0.5	0.9	1.3	1.1	1.2	0.9	1.4	-0.6	0.5	1.1	0.0	0.4	1.0	1.0	0.9	0.0	0.6	0.4
Medication: Seretide 50 evohaler	0.4	0.5	4.1	-0.1	-0.3	-0.4	-2.0	0.1	0.2	0.6	-0.4	-0.1	0.7	-1.4	-0.2	0.1	0.8	-0.2	-0.5	-0.4	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.3	-0.2	0.1	0.1	0.2	0.2	1.3	-0.9	-0.8	1.5	-0.1	-0.2	0.7	1.0	-0.6	-1.2	-0.5	0.2	0.1
Suffer from ‘nerves’	0.4	0.6	2.3	0.7	0.3	1.5	0.0	0.9	-0.5	-1.1	-0.2	-0.5	-0.5	0.1	-1.0	-1.2	-0.3	-0.5	0.2	-0.9	-1.1
Had major operations	0.4	0.5	1.8	0.5	-1.1	0.0	-0.4	0.5	-0.3	-0.4	1.1	-0.5	-0.6	-0.7	-1.0	-0.8	-0.3	-0.4	-0.6	-1.3	-0.7
Family relationship satisfaction	0.4	0.5	2.1	-0.6	0.4	-0.2	-0.1	-0.2	-0.3	0.0	-0.5	0.7	0.7	1.4	0.8	0.8	0.0	0.7	1.4	0.4	0.9
Friendships satisfaction	0.4	0.5	1.9	-0.8	-0.3	0.6	0.6	-0.4	0.1	-0.8	-0.0	0.9	-0.2	1.2	0.5	0.2	-0.5	-0.1	1.4	0.6	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.3	1.0	-1.0	-1.1	-1.0	-0.8	-0.8	-0.3	0.8	-1.0	-0.3	-0.2	-1.8	-1.1	-0.3	0.1	-0.4	-1.6	0.4
Wears glasses or contact lenses	0.4	0.5	3.8	0.9	-0.5	-0.4	0.3	-0.4	-0.9	-0.4	0.7	0.1	0.4	0.7	0.6	0.3	0.3	-0.4	0.2	-0.1	2.0
Eye problems/disorders: Glaucoma	0.4	0.5	3.5	0.5	-0.1	0.1	-0.3	0.1	0.9	0.0	-0.5	0.3	0.8	1.0	0.0	0.8	-0.5	1.3	1.9	0.0	-0.1
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.8	1.0	0.1	-1.1	-1.0	-0.2	-1.3	1.0	0.6	-0.6	0.3	0.5	0.2	-0.5	0.8	0.9	0.2	0.7	-0.1
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.0	0.7	-0.6	-0.8	-0.8	-1.4	-0.8	0.1	0.2	0.4	-0.1	-0.7	-0.9	-0.9	-0.0	0.2	-0.5	-1.0	-0.5
Average weekly beer plus cider intake	0.4	0.6	1.7	1.1	0.3	0.8	0.4	0.6	1.0	0.7	-1.3	1.2	0.7	0.3	0.5	0.9	0.1	0.8	0.3	1.2	0.4
Fractured/broken bones in last 5 years	0.4	0.6	2.5	-0.0	-0.6	0.4	0.9	0.4	1.6	-0.7	-0.5	0.9	-0.8	0.0	1.2	0.6	-0.9	-0.8	-0.3	-0.2	-0.8
Alzheimer’s Disease (including proxy)	0.3	0.4	2.2	1.1	0.1	0.2	0.4	-0.1	0.1	0.2	0.6	0.1	-0.0	1.3	-0.2	-0.1	-0.3	0.9	1.0	0.5	1.5
Major Depression (MDD)	0.3	0.3	1.8	-0.6	0.2	-0.4	0.6	-0.8	-1.2	0.3	1.3	-0.5	-0.4	0.0	-0.5	-0.7	-0.1	-0.2	-0.3	0.0	0.0
Breast Cancer	0.3	0.8	2.3	1.4	0.3	0.8	0.6	0.5	0.3	-0.7	0.7	-1.5	-0.8	-1.2	-0.2	-0.9	-0.2	-1.1	-1.1	-0.9	-1.0
Prostate Cancer	0.3	0.4	1.7	-0.7	-0.1	-0.3	-0.0	-0.0	-0.2	-1.3	-0.6	0.3	0.1	-0.7	-0.0	0.7	-0.8	-1.3	-0.3	-0.6	0.3
Neuroticism (2016)	0.3	0.4	1.5	0.3	-0.5	1.2	0.9	0.6	0.9	-0.9	-0.2	0.1	0.0	-0.9	-0.5	-0.3	-0.1	-0.5	0.4	-0.7	-0.4
Rheumatoid Arthritis	0.3	0.4	1.5	-1.2	0.2	-0.2	-0.9	-0.6	-0.3	0.3	0.2	0.2	1.1	-1.0	-0.3	0.2	1.0	-0.5	-0.5	-0.4	0.1
Blood Platelet Count	0.3	3.7	13.0	-0.1	-2.0	-2.0	-2.2	-2.4	-2.3	-0.6	3.6	-2.8	-1.2	-0.4	-2.6	-2.4	-0.8	-1.3	-1.2	-1.4	1.2
BMI	0.3	2.0	6.9	-0.9	-1.2	-1.5	-1.1	-1.8	-2.3	-0.2	2.6	-1.8	-0.8	-0.0	-1.7	-1.9	-1.0	-0.9	-1.3	0.8	0.5
Smoking Status	0.3	0.8	2.5	-0.6	-0.6	-0.7	-0.6	-0.7	-0.8	-0.9	0.3	-0.9	-0.6	-1.6	-0.8	-0.6	-0.7	-1.3	-1.4	-1.1	-1.0
Chronotype (morning person)	0.3	0.7	1.7	-1.2	-1.3	-0.2	0.2	-0.8	-0.3	-1.1	0.9	-1.3	-1.3	-0.4	-0.9	-0.6	-1.0	-0.7	-0.2	-0.5	0.6
Sensitivity / hurt feelings	0.3	0.5	3.8	1.9	-0.7	-0.3	-0.7	0.2	-0.1	-1.0	-0.1	0.4	-0.6	0.7	-0.4	-0.3	-0.9	-0.0	0.7	-0.8	-0.8
Relative age of first facial hair	0.3	0.7	2.7	-1.1	-0.7	-0.1	-0.4	0.4	-0.2	0.2	0.4	-1.2	-0.7	-1.6	-0.5	-1.1	0.5	-0.6	-1.2	-0.1	-1.4
Systolic blood pressure, automated reading	0.3	1.0	5.6	2.4	0.5	0.1	-0.1	-0.0	-0.6	1.9	0.4	0.6	1.8	0.2	-0.1	-0.2	1.0	1.2	-0.6	-0.1	1.0
Medication for hormone replacement therapy	0.3	0.3	1.3	-0.4	-0.5	-0.2	-0.8	-0.3	-0.7	-0.7	1.2	-0.1	0.1	-0.2	-0.5	-0.2	-0.3	-0.6	-0.3	-1.0	0.0
Medication: Metformin	0.3	0.4	3.5	-1.9	0.1	0.1	0.6	0.1	-0.2	0.1	0.5	-0.6	-0.8	0.8	0.4	-0.1	0.3	0.7	1.0	0.7	-0.3
Townsend deprivation index at recruitment	0.3	0.5	3.1	0.8	-0.2	0.4	0.2	0.7	0.3	0.5	-1.2	0.8	-0.1	-1.8	0.2	0.3	0.0	0.3	-0.8	-0.4	-0.6
Age when periods started (menarche)	0.3	0.8	4.2	-0.6	-0.3	-0.2	-0.1	-0.2	-1.0	0.6	1.7	-2.0	-0.9	0.8	-0.4	-1.3	0.6	0.4	-0.2	0.6	0.7
High blood pressure	0.3	0.9	2.1	0.8	1.0	1.0	1.3	1.4	1.1	1.2	-1.2	0.5	1.0	0.0	0.8	0.9	1.1	1.1	-0.1	0.5	-0.5
Supplements: Glucosamine	0.3	0.4	1.6	0.7	0.8	-0.7	-0.0	-0.6	-0.6	0.6	-0.1	-0.6	0.5	-1.3	-0.2	-0.4	0.3	0.0	-1.0	-0.5	-1.3
Medication: Levothyroxine sodium	0.3	0.6	2.9	1.1	0.4	-0.3	-0.4	0.6	-0.3	1.4	0.3	-0.3	1.0	0.2	-0.1	-0.4	1.7	1.1	-0.2	-0.4	0.5
Had other major operations	0.3	0.3	1.0	-0.2	-0.4	-0.4	-0.8	-0.5	-0.4	0.2	1.0	-0.9	-0.4	0.6	-0.6	-0.7	-0.1	0.6	0.1	-0.4	0.9
Financial difficulties in last 2 years	0.3	0.4	2.1	-1.0	0.3	-0.5	-0.7	-0.6	-1.4	0.4	0.5	-1.3	-0.3	-0.1	-0.5	-0.6	0.3	-0.1	-0.6	0.2	0.7
Allergy	0.3	0.7	2.2	-0.7	0.6	0.7	0.7	0.4	0.8	0.4	-1.3	1.0	0.7	0.1	1.5	0.8	0.5	0.2	0.4	1.2	-1.4
Hip circumference	0.3	1.4	6.0	0.3	1.3	1.6	2.1	2.0	1.3	-0.1	-1.3	-0.5	0.1	-0.1	0.9	0.7	-0.8	0.4	0.4	0.4	-2.4
Number of live births	0.3	0.4	3.7	1.9	-0.1	-0.1	-0.3	0.1	-0.3	0.6	0.3	-0.3	0.5	0.5	0.1	-0.4	0.8	0.7	0.2	0.2	0.5
Medication: Cholesterol lowering	0.3	0.5	4.1	0.9	-0.4	-0.5	-0.3	-0.4	0.1	0.5	0.5	-0.7	0.4	-0.0	-1.0	0.2	0.8	0.6	-0.2	-0.8	2.0
Pulse wave reflection index	0.3	0.4	2.3	-0.1	-0.4	-0.3	-0.5	-0.4	-0.6	-0.4	0.5	-0.6	-1.0	-0.2	-0.9	-0.9	-0.3	-0.3	-0.4	-1.5	-0.5
Blood clot in the leg (DVT)	0.3	0.4	1.4	1.2	-0.1	-0.9	-0.4	-0.3	-0.3	-0.6	0.6	0.3	0.1	-0.2	-0.9	0.4	-0.5	-0.2	-0.2	-1.1	0.7
Medication: Paracetamol	0.3	0.4	4.6	-2.1	-0.3	0.4	0.2	0.7	0.4	0.2	-0.2	0.5	-0.3	-0.3	0.5	0.5	0.3	0.3	0.7	0.6	-0.7
Number of full brothers	0.3	0.4	2.4	-1.6	-0.3	-1.1	-0.8	0.2	-1.0	-0.3	-0.0	-0.5	0.1	-0.6	-0.1	-0.5	0.3	-0.4	-0.0	0.2	-0.9
Health satisfaction	0.3	0.3	1.3	0.9	-0.0	-0.4	-0.2	-0.7	0.4	-0.2	0.6	0.2	-0.6	1.1	0.2	0.2	-0.9	0.7	0.8	0.5	0.4
Eye problems/disorders: None of the above	0.3	0.4	1.9	-0.1	-0.0	0.5	0.8	0.7	0.5	-0.6	-0.4	0.6	-0.5	-0.0	1.4	0.5	0.0	-0.8	-0.3	0.8	-0.6
Neck or shoulder pain in last month	0.3	0.4	2.4	1.5	0.3	0.1	1.0	0.8	0.7	-0.2	0.2	0.5	-0.2	0.5	0.8	0.7	-0.7	0.2	0.6	0.7	-0.6
Migraine (self-reported)	0.3	0.4	1.7	-0.6	-0.0	0.9	0.2	0.9	0.4	-0.8	-0.8	0.6	-0.2	-0.7	0.1	0.2	-0.1	-1.1	-0.1	-0.1	-1.3
Mean time to correctly identify matches	0.3	0.5	1.8	-0.6	-0.3	-0.4	-0.7	-0.6	-1.1	1.1	0.9	0.3	1.0	0.0	0.3	0.0	1.2	0.3	-0.4	0.0	1.4
Overall health rating	0.3	0.7	3.2	0.7	0.3	0.2	-0.1	0.2	0.5	0.7	0.4	0.9	0.2	1.8	0.8	0.5	-0.2	1.6	1.6	0.4	0.3
Qualifications: nursing, teaching	0.3	0.4	2.5	0.9	-0.3	-0.0	0.8	0.4	0.4	-0.1	-0.7	1.6	-0.3	-0.5	0.6	0.7	-0.2	-0.8	-0.3	0.4	-0.4
Commuting to job workplace: Public transport	0.3	0.3	1.7	0.1	0.2	-1.1	-0.3	-0.2	0.3	0.4	-0.7	0.4	0.0	-0.2	0.1	0.6	-0.4	1.0	0.3	-0.3	-1.3
Medication: Paracetamol	0.3	0.5	2.2	-1.5	-0.5	1.0	0.5	1.1	0.8	-0.2	-0.2	0.5	-0.8	0.3	0.4	0.4	-0.1	0.4	1.1	0.5	-0.6
Ever had prostate specific antigen (PSA) test	0.3	0.4	2.3	0.2	-0.3	0.3	0.1	0.2	-1.1	-0.3	0.6	-0.2	0.2	1.4	-0.2	-0.3	-0.1	-0.4	0.3	-0.2	1.5
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.0	-1.1	-0.9	-0.9	-1.1	-1.3	-0.9	-1.4	1.0	-0.5	-1.2	-0.4	-0.6	-0.7	-1.1	-1.4	-0.3	-0.6	0.1
Cholesterol lowering medication	0.3	0.5	1.5	-0.5	0.5	0.8	0.7	1.1	0.2	0.7	-0.2	-0.1	-0.1	0.4	0.2	-0.2	1.2	1.0	0.7	0.7	1.0
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.4	-1.5	-0.5	-1.0	-0.5	-0.4	-0.6	0.5	-0.4	0.7	1.2	-1.5	-0.1	0.7	1.1	-0.5	-0.6	-0.0	-0.4
Worry (Nagel 2018)	0.2	0.5	1.6	0.5	0.1	1.3	0.1	-0.1	-1.3	-0.8	0.7	-0.5	-0.4	0.7	-1.1	-1.2	-0.4	-0.3	0.3	-0.4	0.5
Crohns Disease (2017)	0.2	0.5	1.4	-1.2	-0.7	0.6	-0.0	-0.0	-0.3	-0.3	1.1	-1.1	0.0	0.0	-0.8	-1.1	0.5	-0.6	-0.1	-0.1	1.1
Reaction Time	0.2	0.4	1.4	-0.1	-0.2	-0.3	-0.8	-0.4	-0.8	1.2	1.0	0.3	0.9	-0.2	-0.0	-0.0	1.1	0.3	-0.4	0.2	1.2
Blood Eosinophil Count	0.2	1.9	5.8	0.4	0.2	-1.0	-1.9	-1.1	-2.4	0.5	1.7	-2.3	-0.2	-1.5	-1.9	-1.8	0.7	-0.4	-1.4	-1.1	-0.8
Blood Red Count	0.2	2.1	4.1	-0.2	-1.1	-1.5	-1.6	-1.2	-1.7	-1.3	1.7	-2.0	-1.7	-0.7	-2.0	-2.0	-0.7	-1.2	-1.3	-1.8	0.8
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.2	0.7	0.5	0.2	0.2	0.3	-0.5	-0.5	1.1	-0.9	0.0	0.6	-0.6	-0.4	-0.5	0.2	0.8	-0.4	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.1	-0.4	-0.8	0.3	-0.6	0.1	-0.0	-1.1	0.1	0.2	-0.8	-0.4	-0.3	0.0	-0.6	-0.9	-0.1	-0.9	-0.3
Relative age voice broke	0.2	0.3	1.0	-0.8	0.4	-0.1	0.3	0.7	0.6	0.4	-0.3	-1.0	-0.2	-0.8	0.4	0.2	0.2	0.0	-0.2	0.5	-1.0
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.9	0.6	0.4	0.4	0.4	0.2	-0.3	0.3	1.1	-0.5	0.2	0.9	-0.4	-0.4	0.4	0.6	0.9	0.0	1.4
Waist circumference	0.2	0.6	2.8	1.1	-0.3	-0.5	-0.2	-0.1	-0.3	-0.1	0.1	-1.2	-0.5	-1.0	-0.6	-0.4	-0.8	-0.1	-1.2	-1.0	-1.7
Worrier / anxious feelings	0.2	0.3	1.3	-0.3	0.0	0.8	0.5	0.4	-0.1	-1.1	-0.9	0.7	-0.8	-0.4	0.1	-0.1	-0.7	-0.9	-0.2	-0.3	0.0
Qualifications: A levels/AS levels or equivalent	0.2	0.3	1.4	-0.5	0.7	-0.6	-0.7	-0.1	0.2	-0.0	-0.1	0.0	0.8	0.8	0.7	0.9	0.1	0.4	1.2	0.6	-0.0
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.5	-0.5	-0.1	-0.5	-0.9	-0.4	-0.7	-0.9	0.1	-0.1	-0.6	-0.6	0.1	-0.6	-0.6	-1.0	-0.4	-0.1	-1.2
Medication: Amlodipine	0.2	0.3	1.2	0.6	0.2	-0.7	0.0	-0.0	0.2	0.2	-0.7	-0.4	0.6	-0.7	-0.0	0.8	0.2	-0.3	-1.1	-0.7	0.0
Mouth/teeth dental problems: Loose teeth	0.2	0.3	2.0	-1.4	0.6	0.2	-0.1	0.5	0.6	0.5	0.4	-0.1	0.3	-0.9	-0.7	-0.0	0.4	0.1	-0.4	0.2	-0.1
Pulse rate, automated reading	0.2	0.7	2.2	-0.5	0.4	0.5	0.4	0.7	0.2	0.3	-0.6	0.9	0.7	0.6	1.3	1.2	1.1	0.4	0.9	1.0	1.5
Smoking status: Previous	0.2	0.3	0.9	0.5	-0.9	-0.1	-0.2	-0.4	-0.6	0.6	0.6	-0.5	0.7	-0.5	-0.4	-0.2	0.1	0.3	-0.7	0.8	0.7
Ever had bowel cancer screening	0.2	0.2	1.0	0.5	-0.5	-1.0	-0.2	-0.6	-0.5	0.1	0.1	0.2	-0.3	-0.2	0.1	0.3	-0.3	-0.2	-0.9	0.1	0.7
Back pain experienced in last month	0.2	0.3	1.1	-1.0	-0.0	0.1	-0.1	0.3	0.2	-0.3	0.8	-0.3	-0.8	-0.1	0.5	-0.6	0.4	-1.0	-1.0	0.7	-0.3
Financial situation satisfaction	0.2	0.3	1.0	0.8	-0.5	-0.4	-0.2	-0.7	0.1	-0.4	0.3	0.7	-0.6	0.9	0.4	0.4	-1.0	0.3	0.5	0.3	0.4
High cholesterol (Self-reported)	0.2	0.3	2.3	-0.6	-0.3	0.1	0.1	0.4	0.8	-0.4	-0.5	0.3	-0.3	-0.3	-0.1	0.5	0.8	-0.2	-0.0	-0.5	1.5
Medication: Atorvastatin	0.2	0.2	0.7	-0.0	0.0	-0.1	0.2	-0.6	0.1	0.8	-0.1	-0.4	-0.6	0.7	0.2	-0.3	0.2	0.7	-0.1	0.8	0.6
Ever smoked	0.2	0.4	2.3	-0.0	0.5	0.6	0.5	0.7	0.4	0.0	-1.5	0.5	0.8	-0.9	0.4	0.8	-0.0	-0.4	-0.4	0.6	-0.5
Irritability	0.2	0.3	1.1	-0.3	-0.1	1.0	1.1	0.7	0.6	-0.1	-1.0	0.2	-0.2	-0.2	0.1	0.1	0.1	0.2	0.4	0.1	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.3	1.1	0.1	-0.9	-0.4	-0.3	-0.3	-0.2	0.6	0.5	0.4	0.2	-0.6	0.4	-0.2	0.1	0.1	-0.8	0.7
Alcohol drinker status: Previous	0.2	0.2	0.7	-0.8	-0.2	0.4	-0.4	0.7	0.4	0.1	-0.4	0.9	0.3	-0.1	0.6	0.7	0.4	-0.0	0.0	0.1	0.8
Depression (Nagel 2018)	0.1	0.2	1.1	-1.0	-0.4	0.3	0.0	-0.3	0.1	-0.5	-0.1	0.4	-0.2	-0.3	-0.2	0.6	-0.8	-0.3	0.4	-0.1	-0.4
Triglycerides	0.1	0.2	1.2	-0.4	-1.0	-1.1	-0.3	-0.6	0.1	-0.1	-0.1	0.9	-0.4	-0.1	-0.1	-0.0	-0.3	0.2	-0.2	-0.1	0.3
Blood White Count	0.1	1.1	5.8	0.4	-0.2	-1.1	-1.2	-0.9	-0.7	-0.2	0.3	-0.1	0.0	-1.6	-1.2	-0.9	-0.2	-1.4	-2.4	-1.4	0.0
Hypothyroidism (self reported)	0.1	0.3	1.0	-0.1	0.1	-1.0	-0.7	-0.2	-0.6	0.3	0.7	-1.0	-0.3	-0.3	-0.6	-0.8	0.8	0.2	-0.3	-0.3	0.7
Hair Pigment	0.1	1.6	4.6	-0.1	-1.3	-0.1	-0.9	-0.2	-1.3	-1.3	1.6	-2.0	-1.5	-0.6	-2.1	-1.9	-1.2	-0.6	-0.4	-1.4	-1.5
Tanning	0.1	0.6	3.0	0.3	-1.2	-1.7	-1.3	-1.5	-0.3	0.2	0.2	0.9	1.0	-0.0	-0.5	0.7	-0.2	0.1	0.5	0.2	0.5
Past tobacco smoking	0.1	0.2	1.1	-0.3	0.7	-0.2	-0.2	0.1	0.3	0.2	0.2	0.3	-0.2	1.1	0.3	0.0	0.4	0.5	0.9	-0.4	0.2
Qualifications: None of the above	0.1	0.3	0.7	0.8	-0.5	0.3	-0.4	-0.1	-0.2	-0.6	0.8	-0.4	-0.2	0.9	-0.2	-0.6	-0.8	0.6	0.5	-0.1	-0.0
Noisy workplace	0.1	0.2	1.1	0.2	-0.1	0.3	0.9	0.1	-0.1	0.1	1.1	-0.5	-0.4	0.2	0.0	-0.1	-0.5	-0.0	0.3	0.1	0.3
Medication for pain relief, constipation, heartburn	0.1	0.3	1.2	1.1	0.4	-0.5	-0.6	-0.3	-0.3	0.5	-0.1	0.5	0.8	0.2	0.6	0.1	0.0	-0.1	-0.4	0.8	-0.3
Alcohol intake frequency.	0.1	0.2	0.7	-0.8	-0.5	0.5	-0.4	0.7	0.1	-0.4	-0.1	0.4	-0.4	0.5	0.4	-0.1	0.1	0.0	0.4	-0.5	0.1
Basal cell carcinoma (self-reported)	0.1	0.2	0.7	-0.1	0.2	-0.7	-0.2	-0.9	-0.5	-0.2	0.1	0.5	0.5	0.1	0.4	0.8	0.0	0.1	0.2	-0.5	-0.0

Hub : Genes

MFGE8

Models

Trait associations