[Hub]/) : Traits : Forced vital capacity (FVC) :

chr15:83,167,559-85,883,064

Best TWAS P=1.53e-12 · Best GWAS P=8.47e-20 conditioned to 4.02e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial SCAND2P 0.12 0.05 enet 16 0.08 8.7e-07 -4.249 -5.3 1.0e-07 0.39 0.22 0.66 FALSE
2 GTEx Artery Tibial AC103965.1 0.27 0.26 enet 31 0.30 1.8e-23 4.467 -7.1 1.5e-12 0.56 1.00 0.00 TRUE
3 GTEx Artery Tibial CSPG4P11 0.16 0.24 lasso 4 0.23 3.0e-18 4.467 -5.6 1.9e-08 0.54 1.00 0.00 FALSE
4 GTEx Brain Cerebellar Hemisphere UBE2Q2P1 0.18 0.08 enet 18 0.12 4.2e-04 4.581 5.3 1.5e-07 -0.45 0.18 0.18 FALSE
5 GTEx Brain Cerebellum AC103965.1 0.13 0.02 enet 21 0.01 2.1e-01 4.628 -6.3 3.3e-10 0.67 0.04 0.71 FALSE
6 GTEx Brain Cortex RP11-182J1.14 0.24 0.03 enet 14 0.16 3.2e-05 4.863 6.3 3.0e-10 -0.46 0.07 0.22 FALSE
7 GTEx Breast Mammary Tissue (Male) AC103965.1 0.24 0.14 lasso 4 0.11 1.4e-03 4.509 -5.7 1.6e-08 0.53 0.12 0.28 FALSE
8 GTEx Breast Mammary Tissue (Male) CSPG4P11 0.05 0.02 lasso 6 0.03 7.1e-02 4.910 -5.2 1.6e-07 0.44 0.03 0.09 FALSE
9 GTEx Cells Transformed fibroblasts SCAND2P 0.29 0.20 enet 39 0.21 6.5e-16 -4.249 -6.0 2.6e-09 0.32 0.36 0.60 FALSE
10 GTEx Colon Sigmoid RN7SL417P 0.17 0.06 lasso 4 0.12 6.1e-05 4.831 5.2 2.0e-07 -0.46 0.28 0.09 FALSE
11 GTEx Colon Transverse RP11-182J1.14 0.23 0.19 enet 27 0.18 3.9e-09 4.628 5.6 2.1e-08 -0.46 1.00 0.00 FALSE
12 GTEx Esophagus Gastroesophageal Junction SCAND2P 0.21 0.11 lasso 3 0.12 3.4e-05 -4.249 -5.2 1.6e-07 0.39 0.14 0.35 FALSE
13 GTEx Esophagus Gastroesophageal Junction RP11-382A20.2 0.13 0.03 enet 20 0.07 1.1e-03 3.074 5.6 2.2e-08 -0.12 0.11 0.14 FALSE
14 GTEx Esophagus Mucosa AC103965.1 0.20 0.19 enet 47 0.16 8.4e-11 4.467 -5.2 1.5e-07 0.38 1.00 0.00 FALSE
15 GTEx Nerve Tibial AC103965.1 0.20 0.22 enet 17 0.27 5.1e-19 4.467 -6.1 1.2e-09 0.58 1.00 0.00 FALSE
16 GTEx Pituitary AC103965.1 0.30 0.16 enet 10 0.24 8.4e-07 4.247 -5.2 2.4e-07 0.45 0.40 0.22 FALSE
17 GTEx Prostate RP11-182J1.16 0.24 0.06 enet 27 0.08 6.2e-03 0.093 -5.6 1.7e-08 0.48 0.09 0.10 FALSE
18 GTEx Prostate RP11-182J1.14 0.25 0.09 enet 25 0.09 2.9e-03 4.793 5.7 1.5e-08 -0.35 0.19 0.07 FALSE
19 GTEx Small Intestine Terminal Ileum RP11-182J1.14 0.26 0.01 enet 27 0.12 1.3e-03 -9.050 6.8 1.4e-11 -0.61 0.02 0.63 TRUE
20 The Cancer Genome Atlas Esophageal Carcinoma GOLGA6L5 0.12 0.07 blup 7 0.12 1.0e-04 -4.929 -5.2 2.1e-07 0.35 0.00 0.73 FALSE
21 The Cancer Genome Atlas Glioblastoma Multiforme GOLGA6L5 0.20 0.05 blup 7 0.07 4.7e-03 -4.929 -5.3 1.2e-07 0.35 0.00 0.43 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ZSCAN2 0.11 0.00 blup 46 0.03 1.2e-04 2.966 5.8 5.4e-09 -0.25 0.01 0.38 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GOLGA6L5 0.04 0.01 blup 7 0.03 4.9e-04 4.685 -5.7 1.6e-08 0.44 0.00 0.75 FALSE
24 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma GOLGA6L5 0.06 0.06 blup 7 0.06 1.5e-04 -4.929 -5.2 2.4e-07 0.40 0.00 0.88 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma GOLGA6L5 0.06 0.09 blup 7 0.09 1.5e-10 -3.934 -5.5 4.8e-08 0.40 0.01 0.94 FALSE
26 The Cancer Genome Atlas Liver Hepatocellular Carcinoma WHAMM 0.14 0.05 enet 11 0.08 1.0e-04 -4.681 5.7 1.4e-08 -0.15 0.01 0.98 TRUE
27 The Cancer Genome Atlas Stomach Adenocarcinoma GOLGA6L5 0.07 0.01 enet 5 0.06 5.2e-05 -3.934 -5.3 1.4e-07 0.40 0.01 0.78 FALSE