[Hub]/) : Traits : Forced vital capacity (FVC) :

chr16:86,671-1,488,646

Best TWAS P=3.58e-08 · Best GWAS P=5.76e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum NARFL 0.20 0.30 lasso 2 0.29 2.6e-15 5.4 5.4 7.1e-08 1.00 0.00 1.00 FALSE
2 GTEx Artery Aorta NARFL 0.41 0.36 lasso 7 0.35 4.6e-20 5.4 5.4 5.2e-08 1.00 0.00 1.00 FALSE
3 GTEx Artery Coronary NARFL 0.26 0.16 lasso 6 0.05 1.1e-02 5.4 5.3 9.4e-08 0.98 0.00 0.98 FALSE
4 GTEx Artery Tibial NARFL 0.14 0.16 lasso 2 0.15 1.2e-11 5.4 5.4 5.7e-08 1.00 0.00 1.00 FALSE
5 GTEx Brain Cerebellum NARFL 0.23 0.27 lasso 2 0.24 1.3e-07 5.4 5.4 7.8e-08 1.00 0.00 1.00 FALSE
6 GTEx Colon Sigmoid NARFL 0.40 0.40 lasso 2 0.33 1.9e-12 5.4 5.4 5.3e-08 1.00 0.00 1.00 FALSE
7 GTEx Esophagus Gastroesophageal Junction NARFL 0.24 0.20 lasso 2 0.16 1.9e-06 5.4 5.4 5.8e-08 1.00 0.00 0.99 FALSE
8 GTEx Esophagus Muscularis NARFL 0.24 0.30 lasso 3 0.26 9.3e-16 5.4 5.4 6.5e-08 1.00 0.00 1.00 FALSE
9 GTEx Heart Atrial Appendage NARFL 0.42 0.18 lasso 3 0.15 2.1e-07 5.4 5.2 1.5e-07 0.89 0.00 1.00 FALSE
10 GTEx Heart Left Ventricle HAGHL 0.25 0.15 lasso 4 0.12 7.7e-07 5.1 5.1 2.8e-07 0.86 0.01 0.99 FALSE
11 GTEx Lung NARFL 0.36 0.32 lasso 7 0.31 3.4e-24 5.4 5.4 6.3e-08 0.99 0.00 1.00 FALSE
12 GTEx Nerve Tibial NARFL 0.44 0.35 lasso 5 0.34 2.9e-25 5.4 5.5 4.6e-08 0.99 0.00 1.00 FALSE
13 GTEx Ovary NARFL 0.51 0.44 lasso 6 0.43 9.3e-12 5.4 5.2 2.0e-07 0.99 0.00 1.00 FALSE
14 GTEx Spleen NARFL 0.45 0.34 enet 7 0.37 2.4e-10 5.3 5.4 5.9e-08 0.94 0.00 0.99 FALSE
15 GTEx Stomach NARFL 0.16 0.19 lasso 4 0.17 1.5e-08 5.4 5.5 4.4e-08 1.00 0.00 1.00 FALSE
16 GTEx Testis NARFL 0.41 0.45 lasso 4 0.44 1.4e-21 5.4 5.3 1.3e-07 0.99 0.00 1.00 FALSE
17 GTEx Thyroid NARFL 0.32 0.38 lasso 1 0.38 4.1e-30 5.4 5.4 5.8e-08 1.00 0.00 1.00 FALSE
18 GTEx Uterus NARFL 0.41 0.34 lasso 1 0.32 2.7e-07 5.4 5.4 5.8e-08 1.00 0.00 0.98 FALSE
19 GTEx Whole Blood NARFL 0.11 0.06 lasso 3 0.06 7.4e-06 5.4 5.5 3.6e-08 0.99 0.00 1.00 TRUE
20 METSIM Adipose HAGHL 0.10 0.07 lasso 2 0.06 5.6e-10 5.1 5.4 7.5e-08 0.84 0.01 0.99 FALSE
21 YFS Blood METRN 0.05 0.06 lasso 2 0.06 2.0e-18 5.1 5.4 8.5e-08 0.91 0.01 0.99 FALSE
22 YFS Blood NARFL 0.16 0.19 lasso 3 0.19 1.1e-60 5.4 5.5 4.2e-08 0.97 0.00 1.00 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma METRN 0.02 0.02 lasso 1 0.02 2.0e-04 5.1 5.1 2.8e-07 0.85 0.01 0.96 FALSE
24 The Cancer Genome Atlas Prostate Adenocarcinoma HAGHL 0.03 0.01 blup 41 0.01 2.2e-02 5.1 5.3 1.0e-07 0.78 0.02 0.75 FALSE