[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr2:134,794,256-137,435,625

Best TWAS P=3.73e-12 · Best GWAS P=2.37e-11 conditioned to 0.000146

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	YFS	Blood	DARS	0.17	0.19	enet	36	0.19	8.2e-60	6.0	7.0	3.7e-12	0.48	0.18	0.82	TRUE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	DARS	0.04	0.02	blup	40	0.01	2.1e-02	5.7	6.7	1.8e-11	0.44	0.02	0.93	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	LCT	0.02	0.02	enet	3	0.03	7.6e-07	5.8	-6.3	2.2e-10	-0.47	0.02	0.98	FALSE
13	NTR	Blood	MCM6	0.02	0.02	lasso	2	0.03	1.2e-08	5.4	6.3	3.9e-10	0.47	0.26	0.74	FALSE
27	The Cancer Genome Atlas	Soft Tissue Sarcoma	DARS	0.04	0.04	blup	40	0.04	1.6e-03	6.0	6.3	3.9e-10	0.45	0.02	0.93	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LCT	0.04	0.02	blup	36	0.02	1.9e-03	5.4	-6.1	8.6e-10	-0.50	0.05	0.83	FALSE
11	GTEx	Thyroid	DARS	0.20	0.13	lasso	3	0.15	1.3e-11	5.7	6.1	1.0e-09	0.42	0.27	0.73	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DARS	0.02	0.02	lasso	2	0.02	3.9e-03	6.0	6.1	1.4e-09	0.39	0.01	0.94	FALSE
25	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DARS	0.08	0.10	lasso	4	0.09	8.8e-05	6.0	6.0	1.7e-09	0.41	0.02	0.94	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	DARS	0.15	0.11	enet	4	0.10	3.0e-06	5.7	6.0	1.8e-09	0.41	0.20	0.78	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	CCNT2	0.06	0.03	enet	27	0.05	1.6e-06	5.5	6.0	2.2e-09	0.41	0.03	0.97	FALSE
7	GTEx	Nerve Tibial	DARS	0.13	0.06	lasso	5	0.05	3.2e-04	6.0	6.0	2.4e-09	0.41	0.19	0.72	FALSE
4	GTEx	Esophagus Mucosa	DARS	0.12	0.05	lasso	4	0.04	9.0e-04	5.7	5.9	2.9e-09	0.42	0.16	0.66	FALSE
5	GTEx	Esophagus Muscularis	DARS	0.12	0.11	lasso	3	0.09	3.5e-06	5.7	5.9	3.9e-09	0.40	0.22	0.78	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	DARS	0.22	0.15	enet	13	0.19	4.1e-18	5.6	5.9	4.3e-09	0.33	0.03	0.97	FALSE
6	GTEx	Lung	DARS	0.07	0.05	lasso	4	0.05	5.8e-05	5.7	5.8	4.8e-09	0.40	0.22	0.76	FALSE
16	YFS	Blood	MCM6	0.18	0.15	enet	20	0.20	8.5e-64	5.8	5.7	1.2e-08	0.55	0.45	0.55	FALSE
9	GTEx	Skin Sun Exposed Lower leg	DARS	0.10	0.12	lasso	1	0.11	1.7e-09	5.7	5.7	1.5e-08	0.39	0.41	0.59	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ACMSD	0.04	0.01	blup	46	0.02	2.2e-03	5.0	5.6	2.0e-08	0.37	0.04	0.71	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DARS	0.10	0.08	enet	14	0.11	5.5e-12	6.0	5.6	2.0e-08	0.39	0.02	0.98	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DARS	0.04	0.05	lasso	2	0.05	3.5e-06	5.4	5.6	2.6e-08	0.39	0.02	0.98	FALSE
2	CommonMind	Brain Pre-frontal Cortex	LOC100129961	0.17	0.14	enet	9	0.14	2.6e-17	-5.1	-5.5	2.9e-08	-0.36	0.22	0.78	FALSE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DARS	0.09	0.07	blup	40	0.06	1.6e-04	6.1	5.5	2.9e-08	0.27	0.02	0.97	FALSE
3	GTEx	Artery Aorta	CCNT2	0.12	0.12	lasso	3	0.11	1.9e-06	5.4	5.4	5.6e-08	0.34	0.06	0.92	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCNT2	0.12	0.11	lasso	2	0.10	9.8e-13	5.4	5.4	6.7e-08	0.34	0.06	0.94	FALSE
10	GTEx	Testis	AC016725.4	0.18	0.09	lasso	6	0.09	6.3e-05	-5.2	5.3	1.1e-07	0.37	0.03	0.96	FALSE
12	NTR	Blood	CCNT2	0.01	0.00	blup	370	0.00	6.7e-02	5.1	5.2	1.5e-07	0.35	0.11	0.59	FALSE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	LCT	0.16	0.08	blup	36	0.10	5.3e-04	5.4	-5.2	2.1e-07	-0.45	0.03	0.36	FALSE