Best TWAS P=5.41e-12 · Best GWAS P=2.82e-08 conditioned to 0.0119
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | CYBRD1 | 0.33 | 0.10 | lasso | 10 | 0.26 | 4.6e-14 | -2.4 | 5.4 | 5.6e-08 | -0.70 | 0.08 | 0.92 | FALSE |
| 2 | GTEx | Artery Coronary | CYBRD1 | 0.29 | 0.01 | enet | 44 | 0.11 | 2.0e-04 | -2.4 | 6.9 | 5.4e-12 | -0.49 | 0.05 | 0.52 | TRUE |
| 3 | GTEx | Breast Mammary Tissue (Male) | CYBRD1 | 0.35 | 0.24 | lasso | 6 | 0.20 | 2.4e-05 | -5.6 | 5.5 | 3.5e-08 | -0.91 | 0.01 | 0.92 | FALSE |
| 4 | GTEx | Esophagus Muscularis | CYBRD1 | 0.33 | 0.07 | lasso | 9 | 0.22 | 1.3e-13 | -3.5 | 5.2 | 2.3e-07 | -0.67 | 0.14 | 0.85 | FALSE |
| 5 | METSIM | Adipose | CYBRD1 | 0.08 | 0.06 | lasso | 6 | 0.06 | 8.0e-09 | 4.4 | 5.1 | 2.9e-07 | -0.43 | 0.44 | 0.54 | FALSE |
| 6 | NTR | Blood | METTL8 | 0.03 | 0.02 | lasso | 7 | 0.02 | 1.7e-08 | 4.5 | -5.1 | 2.8e-07 | 0.36 | 0.57 | 0.41 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | CYBRD1 | 0.10 | 0.06 | lasso | 4 | 0.06 | 6.2e-07 | -5.6 | 5.9 | 4.5e-09 | -0.88 | 0.00 | 1.00 | FALSE |