[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr2:177,559,549-179,672,547

Best TWAS P=4.88e-12 · Best GWAS P=1.23e-10 conditioned to 0.146

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
18	GTEx	Spleen	AC073834.3	0.17	0.08	enet	22	0.08	3.6e-03	-5.9	-6.9	4.9e-12	0.81	0.06	0.79	TRUE
9	GTEx	Cells Transformed fibroblasts	AC073834.3	0.13	0.16	lasso	2	0.16	6.7e-12	-6.4	-6.7	2.2e-11	0.99	0.01	0.99	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	AC073834.3	0.10	0.09	lasso	3	0.06	3.7e-03	-6.4	-6.7	2.7e-11	0.97	0.03	0.92	FALSE
5	GTEx	Brain Nucleus accumbens basal ganglia	AC073834.3	0.16	0.01	enet	33	0.05	2.1e-02	-6.0	-6.6	4.0e-11	0.70	0.11	0.75	FALSE
7	GTEx	Breast Mammary Tissue (Male)	AC073834.3	0.22	0.13	enet	18	0.07	8.7e-03	-5.4	-6.6	4.0e-11	0.83	0.08	0.74	FALSE
2	GTEx	Adrenal Gland	AC073834.3	0.12	0.10	lasso	2	0.07	1.5e-03	-6.4	-6.6	4.5e-11	0.99	0.03	0.85	FALSE
11	GTEx	Esophagus Mucosa	AC073834.3	0.06	0.07	lasso	3	0.06	8.3e-05	-6.4	-6.6	5.1e-11	0.99	0.02	0.97	FALSE
16	GTEx	Pituitary	AC073834.3	0.18	0.18	lasso	7	0.12	7.2e-04	-6.1	-6.6	5.2e-11	0.79	0.08	0.76	FALSE
17	GTEx	Skin Sun Exposed Lower leg	AC073834.3	0.07	0.07	lasso	3	0.06	9.5e-06	-6.4	-6.5	5.8e-11	1.00	0.01	0.99	FALSE
19	GTEx	Testis	AC073834.3	0.24	0.23	lasso	7	0.26	4.8e-12	-6.4	-6.5	1.0e-10	0.97	0.01	0.99	FALSE
15	GTEx	Nerve Tibial	AC073834.3	0.09	0.05	lasso	2	0.03	2.1e-03	-6.4	-6.3	2.1e-10	1.00	0.01	0.98	FALSE
6	GTEx	Breast Mammary Tissue	AC073834.3	0.13	0.12	lasso	4	0.08	4.9e-05	-5.8	-6.3	2.8e-10	0.82	0.11	0.88	FALSE
12	GTEx	Esophagus Muscularis	AGPS	0.06	0.03	lasso	3	0.02	2.7e-02	-5.6	-6.2	6.6e-10	0.95	0.04	0.92	FALSE
1	CommonMind	Brain Pre-frontal Cortex	TTC30A	0.12	0.09	lasso	8	0.09	5.4e-11	-6.4	-6.1	9.4e-10	0.98	0.01	0.99	FALSE
3	GTEx	Artery Aorta	AC073834.3	0.11	0.10	enet	11	0.12	3.7e-07	-5.7	-6.1	9.9e-10	0.93	0.06	0.94	FALSE
20	GTEx	Thyroid	AC073834.3	0.12	0.09	enet	9	0.09	1.4e-07	-6.2	-6.1	1.2e-09	0.96	0.02	0.98	FALSE
13	GTEx	Esophagus Muscularis	AC073834.3	0.06	0.02	lasso	3	0.01	5.6e-02	-5.4	-5.9	4.4e-09	0.88	0.05	0.76	FALSE
4	GTEx	Brain Cerebellum	TTC30A	0.13	0.13	lasso	2	0.14	5.8e-05	-5.4	-5.8	5.6e-09	0.87	0.07	0.80	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	PDE11A	0.07	0.02	blup	282	0.04	8.7e-06	-6.0	-5.8	6.3e-09	0.70	0.19	0.76	FALSE
8	GTEx	Breast Mammary Tissue (Female)	AC073834.3	0.04	-0.01	lasso	4	-0.01	6.0e-01	-5.7	-5.8	9.0e-09	0.85	0.04	0.13	FALSE
14	GTEx	Nerve Tibial	AGPS	0.16	0.04	enet	11	0.06	3.8e-05	-4.6	-5.6	1.8e-08	0.64	0.24	0.71	FALSE
22	YFS	Blood	AGPS	0.02	0.01	bslmm	504	0.01	6.5e-05	-6.1	5.6	1.8e-08	-0.70	0.08	0.82	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	TTC30A	0.05	0.03	enet	23	0.04	4.1e-05	-6.4	-5.4	5.5e-08	0.67	0.01	0.98	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	PDE11A	0.05	0.04	blup	622	0.04	1.9e-06	-4.9	-5.4	8.2e-08	0.68	0.55	0.40	FALSE