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Forced vital capacity (FVC)
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chr4:144,882,744-146,788,825
Best TWAS P=1.47e-31 · Best GWAS P=2.64e-30 conditioned to 0.906
145M
145.5M
146M
146.5M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Pancreas
ANAPC10
0.14
0.10
lasso
3
0.10
4.3e-05
-11.4
11.7
1.5e-31
-0.88
0.01
0.97
TRUE
4
ROSMAP
Brain Pre-frontal Cortex
OTUD4
0.04
0.03
lasso
2
0.03
1.4e-04
7.8
-8.1
7.2e-16
0.53
0.62
0.08
TRUE
1
CommonMind
Brain Pre-frontal Cortex
OTUD4
0.06
0.04
bslmm
272
0.04
2.6e-05
-7.1
-7.5
4.3e-14
0.56
0.49
0.44
FALSE
2
GTEx
Brain Hypothalamus
HHIP-AS1
0.12
0.02
enet
16
0.04
4.6e-02
9.4
6.0
1.5e-09
-0.47
0.05
0.33
FALSE