[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr5:133,164,490-134,935,530

Best TWAS P=1.41e-12 · Best GWAS P=1.59e-09 conditioned to 6.96e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
32	METSIM	Adipose	SAR1B	0.06	0.02	bslmm	288	0.03	3.1e-05	-5.90	-7.1	1.4e-12	0.66	0.01	0.97	TRUE
20	GTEx	Colon Transverse	SAR1B	0.11	0.00	enet	17	0.03	1.2e-02	-5.84	-6.7	1.7e-11	0.58	0.02	0.74	TRUE
25	GTEx	Muscle Skeletal	CAMLG	0.08	0.01	enet	28	0.05	2.0e-05	-0.17	-6.3	2.4e-10	0.43	0.02	0.61	TRUE
28	GTEx	Skin Sun Exposed Lower leg	CAMLG	0.11	0.05	lasso	2	0.03	2.9e-03	-5.78	-5.9	4.5e-09	0.92	0.01	0.98	TRUE
36	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CAMLG	0.10	0.04	blup	17	0.04	2.2e-04	-5.90	-5.3	1.3e-07	0.28	0.00	0.96	TRUE
39	The Cancer Genome Atlas	Glioblastoma Multiforme	CAMLG	0.29	0.18	lasso	3	0.13	9.6e-05	-5.90	-6.1	8.6e-10	0.92	0.00	0.99	FALSE
23	GTEx	Lung	CAMLG	0.11	0.11	enet	7	0.11	9.1e-09	-5.87	-6.1	1.3e-09	0.93	0.01	0.99	FALSE
11	GTEx	Brain Frontal Cortex BA9	CAMLG	0.36	0.30	lasso	5	0.26	1.2e-07	-5.87	-6.0	2.2e-09	0.93	0.01	0.99	FALSE
35	YFS	Blood	CAMLG	0.12	0.19	bslmm	295	0.20	1.2e-61	-5.87	-6.0	2.2e-09	0.92	0.01	0.99	FALSE
13	GTEx	Brain Nucleus accumbens basal ganglia	CAMLG	0.29	0.25	enet	8	0.32	2.3e-09	-5.90	-6.0	2.7e-09	0.92	0.01	0.99	FALSE
17	GTEx	Colon Sigmoid	TXNDC15	0.19	0.12	lasso	6	0.10	1.6e-04	-5.84	-5.9	3.1e-09	0.94	0.01	0.98	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	CAMLG	0.47	0.52	lasso	8	0.52	2.2e-79	-5.90	-5.9	3.2e-09	0.94	0.01	0.99	FALSE
5	GTEx	Artery Coronary	CAMLG	0.27	0.20	lasso	8	0.12	5.3e-05	-5.91	-5.9	3.4e-09	0.94	0.01	0.99	FALSE
42	The Cancer Genome Atlas	Brain Lower Grade Glioma	CAMLG	0.08	0.05	lasso	1	0.04	1.8e-05	-5.90	-5.9	3.6e-09	0.93	0.00	1.00	FALSE
26	GTEx	Nerve Tibial	CAMLG	0.25	0.19	lasso	5	0.19	1.5e-13	-5.84	-5.9	3.7e-09	0.95	0.01	0.99	FALSE
30	GTEx	Thyroid	CAMLG	0.21	0.21	lasso	5	0.21	3.3e-16	-5.78	-5.9	3.9e-09	0.95	0.01	0.99	FALSE
21	GTEx	Esophagus Muscularis	CAMLG	0.23	0.17	lasso	5	0.15	1.3e-09	-5.91	-5.9	4.0e-09	0.95	0.01	0.99	FALSE
9	GTEx	Brain Cerebellum	CAMLG	0.31	0.27	lasso	13	0.24	7.5e-08	-5.78	-5.9	4.2e-09	0.95	0.01	0.98	FALSE
38	The Cancer Genome Atlas	Colon Adenocarcinoma	TXNDC15	0.13	0.08	blup	43	0.09	9.7e-06	-5.14	5.9	4.2e-09	-0.75	0.09	0.87	FALSE
46	The Cancer Genome Atlas	Prostate Adenocarcinoma	CAMLG	0.13	0.07	lasso	3	0.05	2.0e-06	-5.90	-5.9	4.3e-09	0.92	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CAMLG	0.39	0.35	lasso	6	0.34	1.8e-42	-5.90	-5.9	4.4e-09	0.93	0.01	0.99	FALSE
4	GTEx	Artery Aorta	CAMLG	0.22	0.17	lasso	3	0.12	2.2e-07	-5.87	-5.9	4.4e-09	0.93	0.01	0.99	FALSE
6	GTEx	Artery Tibial	CAMLG	0.11	0.11	lasso	1	0.09	9.1e-08	-5.87	-5.9	4.4e-09	0.93	0.01	0.99	FALSE
48	The Cancer Genome Atlas	Thyroid Carcinoma	CAMLG	0.26	0.21	lasso	2	0.21	5.2e-20	-5.90	-5.9	4.9e-09	0.93	0.00	1.00	FALSE
31	METSIM	Adipose	CAMLG	0.14	0.18	enet	8	0.21	4.0e-30	-5.87	-5.8	5.6e-09	0.94	0.01	0.99	FALSE
12	GTEx	Brain Hypothalamus	CAMLG	0.28	0.28	lasso	4	0.25	1.3e-06	-5.78	-5.8	7.0e-09	0.95	0.01	0.98	FALSE
27	GTEx	Pituitary	CAMLG	0.20	0.07	enet	10	0.09	3.3e-03	-5.78	-5.8	7.2e-09	0.92	0.01	0.98	FALSE
3	GTEx	Adipose Visceral Omentum	CAMLG	0.15	0.11	lasso	1	0.10	1.0e-05	-5.78	-5.8	7.5e-09	0.95	0.01	0.98	FALSE
10	GTEx	Brain Cortex	CAMLG	0.23	0.28	lasso	10	0.26	1.1e-07	-5.78	-5.8	7.5e-09	0.95	0.01	0.98	FALSE
22	GTEx	Heart Atrial Appendage	CAMLG	0.14	0.03	lasso	4	0.03	2.0e-02	-5.90	-5.6	2.3e-08	0.90	0.01	0.95	FALSE
24	GTEx	Muscle Skeletal	SAR1B	0.10	0.04	lasso	7	0.04	6.1e-05	2.80	-5.5	3.5e-08	0.62	0.02	0.92	FALSE
19	GTEx	Colon Transverse	TXNDC15	0.22	-0.01	lasso	7	-0.01	6.8e-01	-5.06	-5.5	4.8e-08	0.74	0.02	0.78	FALSE
8	GTEx	Brain Cerebellar Hemisphere	CAMLG	0.42	0.24	lasso	8	0.20	8.8e-06	-5.91	-5.5	5.0e-08	0.93	0.01	0.99	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	PHF15	0.26	0.18	lasso	6	0.22	7.1e-08	4.29	5.4	6.9e-08	-0.30	0.49	0.33	FALSE
45	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	TXNDC15	0.23	0.21	enet	10	0.20	1.1e-08	-5.16	5.4	6.9e-08	-0.81	0.03	0.97	FALSE
18	GTEx	Colon Sigmoid	CAMLG	0.16	0.01	lasso	3	0.00	2.9e-01	-5.91	-5.4	8.5e-08	0.88	0.02	0.85	FALSE
37	The Cancer Genome Atlas	Breast Invasive Carcinoma	TXNDC15	0.05	0.06	lasso	3	0.06	1.9e-11	-5.14	5.3	9.4e-08	-0.77	0.15	0.85	FALSE
47	The Cancer Genome Atlas	Prostate Adenocarcinoma	TXNDC15	0.07	0.04	lasso	4	0.04	6.2e-05	-5.06	5.3	1.1e-07	-0.76	0.07	0.74	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SAR1B	0.12	0.06	lasso	6	0.09	8.1e-11	-6.04	-5.3	1.2e-07	0.85	0.00	1.00	FALSE
14	GTEx	Brain Putamen basal ganglia	TXNDC15	0.39	-0.01	enet	22	0.06	1.6e-02	2.53	-5.3	1.5e-07	0.37	0.04	0.08	FALSE
7	GTEx	Brain Cerebellar Hemisphere	TXNDC15	0.51	0.48	lasso	5	0.47	1.2e-13	-5.06	-5.2	1.6e-07	0.72	0.24	0.76	FALSE
44	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TXNDC15	0.03	0.03	blup	35	0.03	5.6e-04	-5.06	5.2	1.7e-07	-0.78	0.02	0.85	FALSE
29	GTEx	Thyroid	TXNDC15	0.24	0.22	enet	8	0.24	3.0e-18	-5.16	-5.2	2.2e-07	0.70	0.43	0.57	FALSE
16	GTEx	Cells Transformed fibroblasts	TXNDC15	0.38	0.31	lasso	11	0.33	4.8e-25	-5.16	5.2	2.4e-07	-0.74	0.43	0.57	FALSE
40	The Cancer Genome Atlas	Glioblastoma Multiforme	TXNDC15	0.27	0.07	lasso	2	0.11	3.2e-04	-5.06	5.2	2.4e-07	-0.74	0.03	0.46	FALSE
43	The Cancer Genome Atlas	Lung Adenocarcinoma	TXNDC15	0.05	0.05	lasso	1	0.04	1.0e-05	-5.16	5.2	2.5e-07	-0.73	0.14	0.84	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	TXNDC15	0.19	0.10	bslmm	324	0.14	1.2e-17	-5.06	-5.1	2.6e-07	0.62	0.33	0.67	FALSE
41	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CAMLG	0.05	0.01	blup	18	0.02	1.4e-03	-5.90	-5.1	2.9e-07	0.35	0.00	0.69	FALSE