[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr5:175,662,866-177,260,129

Best TWAS P=3.56e-13 · Best GWAS P=1.04e-12 conditioned to 0.0318

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAB24 0.14 0.06 enet 14 0.09 4.2e-11 6.3 6.7 2.2e-11 0.71 0.13 0.87 FALSE
2 GTEx Adipose Subcutaneous RAB24 0.17 0.08 enet 26 0.14 1.7e-11 6.2 6.6 4.1e-11 0.62 0.17 0.83 FALSE
3 GTEx Artery Tibial RAB24 0.18 0.09 lasso 3 0.07 2.3e-06 6.2 7.0 1.8e-12 0.77 0.05 0.95 FALSE
4 GTEx Breast Mammary Tissue (Female) MXD3 0.23 0.08 lasso 3 0.09 1.1e-03 5.6 5.3 9.1e-08 0.22 0.06 0.20 FALSE
5 GTEx Esophagus Mucosa UIMC1 0.08 0.00 lasso 5 0.00 3.5e-01 -5.2 -5.6 2.2e-08 -0.35 0.13 0.03 TRUE
6 GTEx Heart Atrial Appendage MXD3 0.33 0.15 enet 24 0.16 1.5e-07 3.6 6.6 3.8e-11 0.29 0.82 0.02 FALSE
7 GTEx Nerve Tibial RAB24 0.27 0.08 enet 32 0.17 6.3e-12 4.4 7.3 3.6e-13 0.47 0.12 0.86 TRUE
8 GTEx Skin Sun Exposed Lower leg MXD3 0.19 0.14 lasso 6 0.12 4.2e-10 5.6 5.1 2.6e-07 0.17 0.96 0.04 FALSE
9 METSIM Adipose RAB24 0.05 0.02 lasso 4 0.02 1.2e-03 6.3 6.2 5.9e-10 0.81 0.04 0.92 FALSE
10 YFS Blood MXD3 0.04 0.03 lasso 4 0.04 5.8e-13 -3.0 5.2 2.1e-07 0.22 1.00 0.00 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma RAB24 0.08 0.04 enet 7 0.06 3.4e-04 -3.6 6.8 1.2e-11 0.54 0.02 0.64 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma F12 0.05 0.03 enet 4 0.03 4.0e-04 5.7 5.6 1.6e-08 0.25 0.00 0.88 FALSE