Best TWAS P=3.29e-14 · Best GWAS P=2.33e-11 conditioned to 0.000477
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TULP4 | 0.16 | 0.08 | bslmm | 596 | 0.12 | 2.9e-14 | -6.5 | -5.3 | 1.4e-07 | -0.55 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | TULP4 | 0.44 | 0.37 | lasso | 12 | 0.32 | 4.3e-09 | 6.7 | 6.5 | 1.0e-10 | 0.98 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Brain Cerebellum | TULP4 | 0.46 | 0.32 | lasso | 15 | 0.28 | 7.6e-09 | 5.3 | 5.4 | 5.4e-08 | 0.91 | 0.17 | 0.83 | FALSE |
| 4 | GTEx | Thyroid | TULP4 | 0.09 | 0.02 | lasso | 4 | 0.03 | 1.4e-03 | 6.5 | 5.5 | 4.8e-08 | 0.66 | 0.05 | 0.72 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TULP4 | 0.09 | 0.05 | blup | 148 | 0.04 | 2.0e-05 | 6.1 | -7.6 | 3.3e-14 | -0.48 | 0.14 | 0.82 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TULP4 | 0.03 | 0.03 | lasso | 3 | 0.02 | 5.1e-03 | 6.6 | -6.7 | 1.8e-11 | -0.99 | 0.01 | 0.96 | FALSE |