[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr7:2,032,803-3,581,391

Best TWAS P=1.03e-12 · Best GWAS P=3.15e-12 conditioned to 0.0233

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	-5.9	-6.1	1.2e-09	0.72	0.33	0.66	FALSE
2	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-6.8	-6.6	5.0e-11	0.86	0.02	0.98	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-6.7	-6.8	7.5e-12	0.90	0.02	0.98	FALSE
4	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-6.8	-6.4	1.7e-10	0.87	0.01	0.99	FALSE
5	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-5.9	-6.4	1.1e-10	0.82	0.04	0.87	FALSE
6	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	5.2	-5.8	7.3e-09	0.62	0.22	0.76	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-5.9	-6.5	5.8e-11	0.82	0.04	0.94	FALSE
8	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-6.9	-6.9	3.9e-12	0.93	0.01	0.99	FALSE
9	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-6.8	-6.9	5.0e-12	0.93	0.01	0.99	FALSE
10	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	-6.8	-7.1	1.0e-12	0.78	0.01	0.99	TRUE
11	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	-5.9	-6.7	1.7e-11	0.83	0.75	0.25	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	4.7	-5.2	1.5e-07	0.55	0.34	0.64	FALSE
13	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	-5.9	-6.7	1.5e-11	0.85	0.17	0.83	FALSE
14	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	-5.9	-5.6	1.8e-08	0.74	0.08	0.74	FALSE
15	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	-5.9	-5.8	5.1e-09	0.68	0.48	0.51	FALSE
16	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-6.5	-6.5	8.6e-11	0.90	0.02	0.91	FALSE
17	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	-5.9	-6.0	1.7e-09	0.75	0.27	0.73	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-6.8	6.1	8.2e-10	-0.89	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	3.7	-5.6	2.6e-08	0.75	0.01	0.67	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	-5.9	-5.9	4.0e-09	0.68	0.08	0.76	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	3.6	-5.8	5.1e-09	0.76	0.06	0.76	FALSE