Best TWAS P=8.93e-30 · Best GWAS P=1.49e-31 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 0.00061 | -11.3 | 11.3 | 8.9e-30 | -0.98 | 0.02 | 0.95 | TRUE |
2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 0.00019 | -4.0 | 7.0 | 1.8e-12 | -0.74 | 0.10 | 0.89 | TRUE |
3 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 0.00262 | -2.3 | -6.2 | 6.9e-10 | 0.40 | 0.34 | 0.06 | FALSE |
4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 0.03380 | 2.9 | -5.2 | 2.4e-07 | 0.12 | 0.02 | 0.60 | TRUE |