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Traits
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Forced vital capacity (FVC)
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chr7:149,847,287-151,252,618
Best TWAS P=1.19e-09 · Best GWAS P=7.84e-13 conditioned to 2.03e-05
149.8M
150M
150.2M
150.4M
150.6M
150.8M
151M
151.2M
0
2
4
6
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12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
METSIM
Adipose
AOC1
0.17
0.08
enet
26
0.11
3.2e-16
5.5
6.1
1.2e-09
0.64
0.51
0.49
TRUE
3
The Cancer Genome Atlas
Testicular Germ Cell Tumors
TMEM176A
0.15
0.00
lasso
10
0.02
5.7e-02
5.8
5.6
2.5e-08
0.66
0.01
0.31
FALSE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
TMEM176A
0.19
0.05
lasso
6
0.13
2.6e-14
-4.8
5.2
2.2e-07
0.64
0.06
0.94
FALSE