Best TWAS P=1.19e-09 · Best GWAS P=7.84e-13 conditioned to 2.03e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | AOC1 | 0.17 | 0.08 | enet | 26 | 0.11 | 3.2e-16 | 5.5 | 6.1 | 1.2e-09 | 0.64 | 0.51 | 0.49 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TMEM176A | 0.19 | 0.05 | lasso | 6 | 0.13 | 2.6e-14 | -4.8 | 5.2 | 2.2e-07 | 0.64 | 0.06 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TMEM176A | 0.15 | 0.00 | lasso | 10 | 0.02 | 5.7e-02 | 5.8 | 5.6 | 2.5e-08 | 0.66 | 0.01 | 0.31 | FALSE |