[Hub]/) : Traits : Forced vital capacity (FVC) :

chr10:123,438,113-124,889,817

Best TWAS P=2.3e-09 · Best GWAS P=2.76e-24 conditioned to 1.64e-15

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -6.7 -6.0 2.3e-09 0.30 0.44 0.07 TRUE
2 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 3.5 -5.5 3.0e-08 0.32 0.95 0.00 FALSE
3 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ARMS2 0.23 0.20 lasso 2 0.21 7.0e-09 -4.9 -5.2 1.5e-07 0.55 0.92 0.02 TRUE