[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1) : →

chr1:16,273,995-18,027,554

Best TWAS P=3.92e-09 · Best GWAS P=1.41e-08 conditioned to 0.486

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Liver	MST1P2	0.20	0.14	lasso	4	0.10	7.6e-04	5.5	5.9	3.9e-09	0.92	0.01	0.96	TRUE
12	GTEx	Testis	MST1L	0.45	0.20	enet	34	0.25	2.5e-11	-5.1	-5.7	9.0e-09	-0.82	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MST1P9	0.15	0.13	enet	15	0.13	1.5e-14	-4.7	-5.7	1.0e-08	-0.79	0.02	0.98	FALSE
3	GTEx	Brain Cerebellum	MST1L	0.21	0.13	lasso	2	0.09	1.7e-03	5.5	-5.7	1.6e-08	-0.92	0.01	0.94	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	ATP13A2	0.05	0.00	enet	1	0.01	1.6e-02	-5.6	5.6	1.8e-08	0.78	0.00	0.68	FALSE
11	GTEx	Testis	CROCC	0.18	0.03	lasso	4	0.04	1.0e-02	5.5	-5.6	2.8e-08	-0.79	0.03	0.76	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MFAP2	0.17	0.22	enet	10	0.23	6.8e-26	-5.6	5.6	2.8e-08	0.84	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MST1P9	0.08	0.05	blup	38	0.08	4.2e-06	5.5	-5.5	3.0e-08	-0.85	0.01	0.98	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MST1P9	0.04	0.02	lasso	5	0.02	1.0e-03	-5.1	-5.5	3.7e-08	-0.86	0.02	0.92	FALSE
8	GTEx	Nerve Tibial	MFAP2	0.09	0.06	lasso	3	0.07	9.7e-06	5.7	5.5	4.0e-08	0.89	0.01	0.99	FALSE
6	GTEx	Heart Atrial Appendage	MST1P2	0.20	0.09	lasso	4	0.09	6.7e-05	-4.7	5.4	5.7e-08	0.85	0.01	0.98	FALSE
13	GTEx	Thyroid	MST1P2	0.18	0.11	lasso	9	0.13	2.7e-10	5.5	5.4	7.7e-08	0.88	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	MST1P9	0.11	0.11	blup	38	0.08	1.3e-04	-5.6	-5.4	7.7e-08	-0.79	0.00	0.99	FALSE
14	GTEx	Whole Blood	MST1L	0.08	0.02	enet	12	0.04	6.3e-05	-3.1	-5.3	1.0e-07	-0.79	0.02	0.97	FALSE
9	GTEx	Pituitary	MST1L	0.39	0.22	lasso	5	0.20	1.2e-05	5.5	-5.3	1.4e-07	-0.86	0.01	0.94	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	MST1P2	0.14	0.03	lasso	4	0.01	5.0e-02	5.5	5.3	1.4e-07	0.95	0.01	0.94	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	MST1P9	0.13	0.09	lasso	6	0.11	3.3e-11	5.5	-5.3	1.5e-07	-0.91	0.01	0.99	FALSE
5	GTEx	Esophagus Mucosa	MST1P2	0.32	0.06	enet	22	0.12	3.3e-08	-4.7	5.2	1.6e-07	0.51	0.03	0.96	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ATP13A2	0.08	0.06	lasso	5	0.08	6.9e-10	5.5	5.2	1.7e-07	0.90	0.01	0.99	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	MST1L	0.31	0.10	lasso	6	0.14	2.2e-05	-5.1	-5.2	1.8e-07	-0.79	0.02	0.96	FALSE
2	GTEx	Adipose Visceral Omentum	MST1L	0.15	0.08	enet	21	0.11	1.7e-06	5.7	-5.2	2.0e-07	-0.82	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	MST1P9	0.15	0.13	enet	14	0.17	6.2e-19	-5.6	-5.2	2.3e-07	-0.69	0.00	1.00	FALSE