TWAS hub - MST1L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1210	0.0430	6.6e-07	0.136	NA	0.109	NA	0.112	3.0e-11	NA	3.4e-09	NA	2.0e-09
2	GTEx	Adipose Visceral Omentum	0.1510	0.0490	1.8e-05	0.083	NA	0.114	NA	0.095	4.2e-05	NA	1.7e-06	NA	1.2e-05
3	GTEx	Artery Aorta	0.2310	0.0620	3.6e-08	0.158	NA	0.193	NA	0.166	5.0e-09	NA	7.0e-11	NA	1.9e-09
4	GTEx	Artery Tibial	0.2069	0.0617	3.7e-07	0.076	NA	0.122	NA	0.125	1.5e-06	NA	8.8e-10	NA	5.0e-10
5	GTEx	Brain Cerebellum	0.2070	0.0810	1.1e-03	0.127	NA	0.044	NA	0.085	1.4e-04	NA	2.0e-02	NA	1.7e-03
6	GTEx	Brain Cortex	0.3770	0.1580	1.9e-03	0.119	NA	0.091	NA	0.010	3.7e-04	NA	1.7e-03	NA	1.6e-01
7	GTEx	Brain Hippocampus	0.2611	0.1121	4.2e-03	0.218	NA	0.168	NA	0.196	7.7e-06	NA	9.6e-05	NA	2.3e-05
8	GTEx	Breast Mammary Tissue	0.2330	0.0810	9.7e-05	0.138	NA	0.106	NA	0.121	1.5e-07	NA	4.4e-06	NA	8.6e-07
9	GTEx	Breast Mammary Tissue (Male)	0.1917	0.1154	6.7e-02	-0.013	NA	-0.013	NA	-0.011	8.5e-01	NA	9.3e-01	NA	6.7e-01
10	GTEx	Breast Mammary Tissue (Female)	0.0178	0.0401	3.6e-01	0.036	NA	-0.007	NA	0.056	3.0e-02	NA	5.8e-01	NA	9.2e-03
11	GTEx	Cells EBV-transformed lymphocytes	0.3080	0.0930	3.2e-06	0.096	NA	0.131	NA	0.143	4.9e-04	NA	4.7e-05	NA	2.2e-05
12	GTEx	Cells Transformed fibroblasts	0.0900	0.0370	2.1e-04	0.023	NA	0.028	NA	0.020	6.8e-03	NA	3.1e-03	NA	1.1e-02
13	GTEx	Esophagus Mucosa	0.1270	0.0430	3.4e-06	0.069	NA	0.068	NA	0.058	2.3e-05	NA	2.7e-05	NA	9.1e-05
14	GTEx	Heart Left Ventricle	0.0868	0.0366	5.1e-04	0.068	NA	0.065	NA	0.072	1.8e-04	NA	2.3e-04	NA	1.1e-04
15	GTEx	Muscle Skeletal	0.1674	0.0432	6.2e-12	0.118	NA	0.130	NA	0.146	1.3e-11	NA	9.4e-13	NA	3.5e-14
16	GTEx	Nerve Tibial	0.2326	0.0574	2.3e-11	0.165	NA	0.206	NA	0.225	9.0e-12	NA	1.5e-14	NA	6.6e-16
17	GTEx	Ovary	0.1890	0.0970	9.5e-03	0.075	NA	0.041	NA	0.027	6.7e-03	NA	3.5e-02	NA	7.3e-02
18	GTEx	Pituitary	0.3900	0.1530	2.4e-03	0.222	NA	0.174	NA	0.196	2.8e-06	NA	3.8e-05	NA	1.1e-05
19	GTEx	Skin Not Sun Exposed Suprapubic	0.1530	0.0530	1.4e-05	0.147	NA	0.082	NA	0.134	1.9e-08	NA	2.8e-05	NA	8.2e-08
20	GTEx	Skin Sun Exposed Lower leg	0.3420	0.0610	0.0e+00	0.196	NA	0.254	NA	0.228	4.6e-16	NA	5.6e-21	NA	8.4e-19
21	GTEx	Testis	0.4540	0.0800	5.9e-09	0.200	NA	0.247	NA	0.247	3.0e-09	NA	2.6e-11	NA	2.6e-11
22	GTEx	Thyroid	0.0820	0.0390	1.5e-03	0.027	NA	0.018	NA	0.031	3.8e-03	NA	1.5e-02	NA	1.8e-03
23	GTEx	Whole Blood	0.0830	0.0330	2.3e-05	0.020	NA	0.044	NA	0.041	5.2e-03	NA	6.3e-05	NA	1.1e-04
24	ROSMAP	Brain Pre-frontal Cortex	0.2156	0.0538	1.8e-08	0.011	0.06	0.073	0.064	0.053	1.1e-02	3e-08	1.0e-09	1.3e-08	2.2e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Lung FEV1/FVC ratio	40.8	206.9	295.8	12.2	17.2	14.0	15.5	16.5	13.2	12.6	13.7	1.6	13.4	15.8	13.8	14.2	15.9	15.5	17.1	15.3	14.2	16.1	14.0	14.8	14.4	16.3	9.9
Forced vital capacity (FVC), Best measure	24.1	88.0	132.2	-7.5	-10.8	-9.3	-9.8	-11.5	-9.0	-8.0	-8.0	2.1	-8.0	-10.7	-9.5	-9.6	-10.1	-9.3	-10.8	-8.9	-10.4	-10.3	-9.7	-10.7	-8.8	-10.9	-7.0
Forced vital capacity (FVC)	22.0	84.6	125.4	-7.0	-10.9	-9.2	-9.8	-11.2	-9.2	-7.4	-7.9	1.2	-7.6	-10.6	-9.4	-9.3	-9.7	-9.0	-10.4	-8.4	-10.2	-10.0	-9.7	-10.7	-8.4	-10.8	-7.3
Height	19.7	380.4	529.0	-16.8	-22.9	-19.3	-21.5	-20.6	-17.5	-16.9	-19.0	-1.9	-18.3	-22.5	-19.6	-19.7	-21.1	-21.1	-22.7	-18.2	-18.6	-21.8	-19.6	-21.5	-17.9	-23.0	-15.5
Standing height	15.5	153.5	210.2	-10.2	-14.5	-12.5	-13.2	-13.6	-11.4	-10.2	-11.4	0.1	-11.2	-14.3	-12.6	-13.4	-13.3	-13.0	-14.5	-11.1	-12.4	-13.8	-12.9	-14.0	-12.0	-14.3	-9.4
Comparative height size at age 10	14.4	79.2	108.2	-7.9	-10.2	-9.4	-9.5	-9.8	-7.6	-8.2	-8.6	-0.2	-8.5	-9.8	-8.6	-9.6	-9.8	-9.6	-10.4	-7.7	-9.3	-10.1	-9.3	-9.5	-8.0	-10.0	-6.4
Lung FVC	12.3	62.4	91.8	-6.1	-9.5	-8.4	-9.2	-9.6	-7.7	-6.9	-7.1	2.0	-6.7	-8.8	-8.2	-7.1	-8.5	-8.2	-8.6	-6.8	-9.3	-9.0	-7.2	-8.9	-7.2	-9.5	-4.6
Forced expiratory volume in 1-second (FEV1), predicted	11.1	23.0	37.8	-4.2	-5.6	-5.3	-4.8	-5.1	-4.3	-4.0	-4.5	1.3	-4.4	-6.2	-4.2	-5.5	-5.1	-4.9	-5.9	-3.8	-4.6	-5.2	-4.4	-5.9	-4.0	-5.5	-4.1
Sitting height	8.6	61.0	86.3	-6.0	-9.2	-8.4	-8.4	-8.9	-6.7	-6.2	-7.2	0.6	-6.8	-9.3	-7.8	-8.2	-8.3	-8.1	-9.2	-7.5	-8.2	-8.7	-7.6	-8.9	-7.5	-9.2	-5.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	7.2	8.6	12.9	3.0	2.9	2.7	2.9	3.3	2.5	2.7	3.0	0.7	3.1	3.6	3.1	3.3	3.5	3.2	3.3	1.9	3.1	3.4	2.9	2.9	2.5	3.4	1.6
Rheumatoid Arthritis	6.8	9.3	16.2	-2.3	-3.8	-4.0	-3.4	-2.7	-2.8	-2.9	-3.2	-0.4	-2.6	-3.4	-3.5	-3.5	-2.9	-3.4	-3.3	-2.3	-2.9	-3.1	-2.9	-3.3	-3.4	-3.6	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	6.5	20.8	34.5	-3.3	-5.0	-4.4	-4.6	-5.9	-4.7	-3.5	-3.3	2.7	-3.4	-5.4	-5.0	-4.6	-4.7	-3.9	-4.8	-3.9	-5.6	-4.8	-5.1	-5.8	-3.9	-5.3	-3.8
Forced expiratory volume in 1-second (FEV1)	5.8	19.6	33.1	-2.8	-5.2	-4.3	-4.8	-5.7	-4.7	-3.2	-3.4	1.9	-3.1	-5.2	-5.0	-4.5	-4.4	-3.9	-4.6	-3.6	-5.3	-4.6	-5.1	-5.7	-3.8	-5.3	-3.8
Waist Hip Ratio (WHR)	5.5	24.5	37.2	-5.7	-5.5	-5.8	-5.4	-4.3	-4.0	-5.0	-5.5	-0.7	-5.8	-4.0	-5.7	-4.7	-5.8	-5.9	-6.0	-4.8	-4.1	-5.7	-4.7	-2.9	-6.1	-4.8	-1.4
Impedance of leg (right)	5.4	26.0	39.7	-4.2	-6.3	-4.6	-6.1	-4.9	-5.9	-4.6	-5.2	-0.9	-4.6	-6.2	-5.8	-5.7	-5.4	-5.3	-5.8	-4.0	-3.8	-5.5	-5.4	-5.3	-5.0	-6.2	-2.3
Ever highly irritable/argumentative for 2 days	5.4	6.4	10.6	2.1	2.8	2.6	2.5	1.7	3.1	3.1	2.4	1.0	2.2	3.3	1.7	2.5	2.2	2.6	2.7	2.7	2.5	2.4	2.9	3.0	1.5	2.7	3.2
Ovarian Cancer	5.3	7.0	11.1	2.6	2.8	2.9	3.1	2.4	1.4	2.8	3.2	-1.1	2.9	3.3	2.3	2.6	3.0	3.2	3.1	1.6	2.1	2.9	2.0	2.7	2.6	3.0	2.3
Impedance of arm (left)	5.2	24.3	39.2	-3.7	-6.3	-4.4	-5.5	-4.5	-6.0	-4.8	-4.5	-1.4	-4.0	-5.7	-5.3	-5.6	-4.8	-5.1	-5.3	-3.9	-3.9	-5.0	-6.0	-5.5	-4.7	-5.8	-3.7
Impedance of whole body	5.2	26.3	42.0	-3.9	-6.5	-4.4	-5.9	-4.9	-6.2	-4.8	-4.9	-1.4	-4.3	-6.2	-5.8	-5.8	-5.2	-5.3	-5.7	-4.0	-3.9	-5.4	-5.9	-5.5	-5.1	-6.2	-3.0
Average weekly fortified wine intake	5.1	5.9	13.5	-2.9	-2.6	-2.2	-2.6	-1.8	-0.9	-2.9	-2.3	-1.4	-3.0	-1.7	-1.8	-1.2	-2.7	-2.9	-3.0	-3.0	-1.9	-2.8	-3.0	-1.4	-2.7	-1.9	-3.7
Impedance of arm (right)	5.1	23.9	37.7	-3.8	-6.1	-4.1	-5.4	-4.5	-5.7	-4.8	-4.6	-1.3	-4.1	-5.8	-5.2	-5.7	-4.8	-5.1	-5.3	-3.5	-3.9	-5.1	-5.9	-5.4	-4.5	-5.9	-4.0
Hair/balding pattern: Pattern 3	4.7	7.0	10.5	2.9	3.0	2.2	3.0	2.2	1.8	2.8	3.1	1.4	3.0	2.7	2.7	3.2	3.1	2.9	2.8	2.4	1.5	2.9	2.8	2.1	2.2	2.5	3.2
Heart disease (siblings)	4.6	5.6	9.4	-2.3	-2.9	-2.5	-2.3	-2.0	-1.9	-2.4	-2.5	-1.4	-2.6	-2.4	-2.0	-2.4	-2.6	-2.9	-3.1	-2.7	-2.0	-2.7	-2.5	-2.1	-1.6	-2.7	-1.1
Impedance of leg (left)	4.5	22.1	34.8	-3.5	-5.9	-3.9	-5.5	-4.7	-5.7	-4.0	-4.5	-1.4	-4.0	-5.8	-5.3	-5.4	-4.9	-4.7	-5.3	-3.9	-3.3	-4.9	-5.2	-4.8	-5.0	-5.8	-2.1
Average weekly red wine intake	3.6	5.4	8.6	-2.5	-2.5	-2.0	-2.9	-2.3	-2.2	-2.2	-2.5	0.1	-2.5	-2.3	-2.8	-2.1	-2.8	-2.6	-2.7	-1.3	-1.5	-2.7	-2.7	-2.4	-1.7	-2.7	-1.2
Ever had prostate specific antigen (PSA) test	3.5	4.1	6.7	-1.7	-2.6	-2.2	-2.2	-2.6	-1.9	-0.9	-1.7	-1.9	-1.8	-1.8	-1.5	-2.1	-2.2	-2.1	-2.3	-1.7	-2.5	-2.3	-2.1	-2.4	-1.3	-1.7	-2.2
Alzheimer’s Disease (including proxy)	3.4	4.9	7.7	2.1	2.3	1.8	2.5	2.2	2.1	2.6	2.1	-1.3	2.1	2.1	2.8	1.7	2.5	2.3	2.3	1.6	1.7	2.5	2.7	1.6	2.7	2.7	1.4
Leg pain on walking	3.4	4.2	7.1	2.4	1.7	1.7	2.2	1.5	1.7	2.7	2.4	-0.3	2.4	2.6	2.2	1.9	2.3	2.0	2.4	2.0	1.4	2.3	2.2	2.4	1.3	2.2	1.3
Frequency of depressed mood in last 2 weeks	3.3	4.6	11.0	1.5	2.9	1.0	2.7	2.3	3.3	2.0	1.4	-0.8	1.6	2.2	2.4	1.1	2.2	2.2	2.1	1.9	2.0	2.4	2.6	1.6	1.7	2.6	2.5
Hand grip strength (right)	3.3	8.9	18.7	-2.8	-3.8	-3.2	-3.1	-2.6	-1.7	-2.7	-3.0	-1.0	-3.1	-3.6	-2.2	-2.2	-3.2	-3.2	-3.9	-4.3	-2.0	-3.4	-2.4	-3.1	-3.0	-3.4	-2.3
LDL Cholesterol	3.2	5.0	9.9	-2.6	-2.2	-2.8	-1.8	-0.5	-1.0	-3.1	-2.5	-1.9	-2.7	-2.5	-1.8	-2.0	-2.0	-2.8	-2.8	-2.5	-1.1	-2.2	-1.9	-1.5	-3.0	-2.6	-1.9
Peak expiratory flow (PEF)	3.0	7.0	10.7	3.0	2.9	2.7	2.3	2.3	2.0	2.6	2.9	0.9	3.2	2.4	2.5	2.7	3.1	3.2	3.3	2.8	2.3	3.0	2.5	2.1	3.0	2.9	1.9
Alzheimer’s Disease (in father)	2.9	3.2	6.7	1.7	1.9	1.9	2.0	1.9	1.7	1.9	1.6	-0.7	1.7	1.7	1.8	0.5	2.0	1.8	1.9	1.6	2.0	2.1	2.6	1.8	1.5	2.0	1.5
BMI	2.8	16.5	33.8	1.8	5.2	2.4	4.3	5.3	4.9	2.7	3.0	-1.5	2.4	5.7	4.7	4.4	4.0	3.1	4.3	3.4	3.5	4.1	4.6	5.8	3.2	5.5	3.0
Trunk fat-free mass	2.7	15.7	23.5	-3.5	-4.3	-4.8	-4.0	-4.6	-2.4	-2.9	-3.6	0.6	-3.8	-4.3	-3.5	-4.4	-4.3	-4.2	-4.7	-4.0	-4.8	-4.6	-3.7	-4.6	-3.5	-4.2	-3.1
Trunk predicted mass	2.7	15.3	22.7	-3.4	-4.3	-4.8	-4.0	-4.6	-2.4	-2.8	-3.6	0.6	-3.7	-4.2	-3.5	-4.4	-4.3	-4.2	-4.6	-4.0	-4.7	-4.5	-3.6	-4.5	-3.5	-4.1	-3.1
Deep venous thrombosis (DVT) (self-reported)	2.7	3.5	5.4	-1.7	-2.2	-1.9	-2.2	-1.1	-1.6	-0.9	-2.3	-1.9	-2.0	-2.1	-2.2	-2.0	-1.9	-2.3	-2.0	-1.7	-1.0	-2.0	-1.6	-1.8	-1.7	-2.3	-1.4
Age at last live birth	2.6	3.8	5.9	-2.3	-1.3	-1.5	-1.4	-1.8	-2.4	-2.2	-1.7	0.2	-2.2	-2.1	-2.3	-2.0	-2.2	-1.9	-2.3	-1.6	-2.0	-2.0	-2.4	-1.6	-2.3	-2.2	-1.2
Body Mass Index (BMI) (2010)	2.5	3.4	6.4	1.5	2.0	1.9	2.5	2.2	1.3	1.7	2.0	0.2	1.6	2.0	2.5	2.4	2.0	2.0	1.8	0.8	2.4	2.1	1.1	1.9	0.9	2.2	0.5
Schizophrenia (2014)	2.5	5.4	8.2	2.4	2.4	1.8	2.5	2.1	2.4	2.2	2.1	1.1	2.4	2.2	2.6	2.4	2.5	2.9	2.7	2.1	2.5	2.6	2.8	1.0	2.7	2.4	1.9
Hand grip strength (left)	2.5	6.5	11.1	-2.3	-3.0	-2.6	-2.5	-2.2	-2.2	-2.2	-2.4	-0.1	-2.4	-3.3	-2.4	-2.5	-2.6	-2.4	-3.0	-3.0	-2.1	-2.8	-2.6	-3.3	-2.2	-2.9	-2.3
Bipolar Disorder or Schizophrenia	2.4	6.0	11.9	2.4	2.3	2.2	2.8	2.3	2.0	2.4	2.3	0.6	2.3	2.4	3.0	2.7	2.5	2.8	2.6	2.1	2.7	2.7	3.5	1.3	2.9	2.8	1.7
Loneliness, isolation	2.4	3.4	6.8	1.5	1.9	2.4	1.5	1.1	2.5	1.6	1.2	1.0	1.5	2.3	1.6	2.6	1.3	1.7	1.8	1.4	2.2	1.5	2.3	2.1	1.9	1.9	2.1
Age at first live birth	2.3	4.1	7.6	-2.1	-1.8	-1.4	-2.3	-1.6	-2.0	-2.5	-2.0	-0.3	-2.2	-2.2	-2.4	-1.8	-2.2	-2.2	-2.3	-1.9	-1.2	-2.2	-2.1	-2.0	-2.8	-2.2	-1.6
Arm predicted mass (right)	2.3	11.7	19.2	-3.5	-3.4	-4.4	-3.7	-3.7	-1.8	-2.8	-3.4	0.3	-3.7	-3.3	-3.1	-3.7	-3.9	-3.8	-4.0	-3.5	-4.2	-4.1	-2.8	-3.4	-3.2	-3.3	-2.5
Blood Red Count	2.2	21.1	34.3	-3.8	-5.1	-4.2	-5.2	-5.2	-4.8	-3.6	-4.3	-1.2	-4.1	-5.8	-4.9	-4.9	-5.0	-4.8	-5.0	-3.8	-4.6	-5.1	-4.4	-4.9	-4.7	-5.9	-2.6
Waist circumference	2.2	8.1	18.1	-3.9	-2.5	-4.3	-3.0	-2.0	-1.3	-2.9	-3.2	-0.9	-3.8	-1.5	-2.6	-2.9	-3.2	-3.7	-3.1	-2.6	-3.4	-3.5	-2.3	-1.3	-3.5	-1.9	-0.7
Blood clot in the leg (DVT)	2.2	2.8	5.0	-1.5	-1.9	-1.7	-1.8	-0.9	-1.4	-0.5	-2.1	-2.2	-1.8	-1.9	-1.9	-2.1	-1.6	-2.0	-1.8	-1.5	-0.7	-1.6	-1.4	-1.5	-1.5	-2.0	-1.5
Whole body fat-free mass	2.1	12.0	19.4	-3.1	-3.6	-4.3	-3.5	-4.0	-2.0	-2.5	-3.1	0.4	-3.4	-3.6	-3.0	-3.9	-3.8	-3.7	-4.0	-3.5	-4.4	-4.0	-3.3	-4.0	-3.0	-3.4	-3.1
Basal metabolic rate	2.1	11.5	19.0	-3.3	-3.5	-4.4	-3.4	-3.7	-1.9	-2.6	-3.2	0.0	-3.5	-3.3	-2.9	-3.8	-3.7	-3.7	-3.9	-3.4	-4.3	-3.9	-3.3	-3.7	-3.0	-3.2	-3.1
Major Depression (MDD)	2.0	2.4	9.3	-0.8	-1.7	-1.3	-1.6	-2.2	-2.3	-0.9	-0.7	0.0	-0.9	-1.9	-1.5	-1.6	0.0	-1.1	-1.5	-1.7	-2.6	-1.6	0.0	-3.0	-0.8	-1.7	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.3	10.2	-0.9	-2.5	-2.1	-2.2	-3.2	-3.0	-1.3	-1.2	1.5	-1.0	-2.0	-2.6	-1.7	-2.0	-1.6	-1.8	-1.7	-2.9	-1.9	-2.1	-2.8	-2.2	-2.2	-1.0
Whole body water mass	2.0	11.5	18.3	-3.1	-3.5	-4.2	-3.4	-3.9	-1.9	-2.4	-3.1	0.4	-3.3	-3.5	-3.0	-3.9	-3.7	-3.6	-4.0	-3.4	-4.3	-3.9	-3.2	-3.9	-3.0	-3.4	-3.1
Arm predicted mass (left)	2.0	9.9	16.9	-3.1	-3.2	-4.1	-3.2	-3.6	-1.5	-2.3	-3.0	0.1	-3.3	-3.1	-2.7	-3.6	-3.6	-3.4	-3.8	-3.2	-3.9	-3.7	-2.9	-3.2	-2.9	-3.0	-2.6
Tinnitus: Yes, but not now, but have in the past	1.9	2.1	4.5	1.6	1.5	1.3	2.0	1.5	0.5	1.3	1.9	-0.1	1.6	1.6	2.1	1.5	1.9	1.5	1.3	0.3	0.8	1.7	1.1	1.8	1.1	1.8	0.2
Weight	1.9	9.2	16.5	-3.5	-3.0	-4.1	-3.3	-2.7	-1.7	-2.8	-3.1	-1.2	-3.5	-2.4	-2.5	-3.2	-3.3	-3.7	-3.4	-3.1	-3.8	-3.6	-2.7	-2.5	-3.0	-2.5	-2.6
Arm fat-free mass (right)	1.9	9.6	16.8	-3.0	-3.2	-4.1	-3.3	-3.6	-1.4	-2.3	-2.9	0.6	-3.1	-2.9	-2.7	-3.5	-3.5	-3.4	-3.6	-3.2	-4.1	-3.7	-2.5	-3.2	-2.8	-2.9	-2.3
Eye problems/disorders: Cataract	1.9	2.2	5.8	-2.0	-0.7	-0.7	-1.8	-2.4	-0.8	-1.7	-1.5	1.1	-2.0	-0.9	-1.4	-0.2	-2.4	-1.6	-1.8	-1.2	-2.1	-2.4	-0.3	-0.6	-0.6	-1.1	-0.5
Hip circumference	1.8	7.9	15.4	-3.5	-2.6	-3.9	-3.3	-2.3	-1.3	-2.8	-3.0	-0.8	-3.4	-2.1	-2.4	-2.9	-3.2	-3.6	-3.1	-2.2	-3.6	-3.5	-2.4	-2.2	-2.8	-2.2	-2.0
Alcohol intake versus 10 years previously	1.8	2.7	7.3	2.6	1.3	2.7	2.2	0.4	0.2	2.2	2.3	-0.2	2.4	0.9	2.4	1.6	1.8	2.1	1.4	0.4	1.1	1.9	0.7	1.2	0.9	1.3	0.1
Chronic bronchitis/emphysema (mother)	1.8	2.1	4.8	1.1	1.5	1.0	1.8	1.4	1.8	0.3	1.4	0.8	1.2	1.8	1.7	1.0	1.4	1.5	1.7	1.4	1.2	1.6	1.1	1.9	0.8	1.8	2.2
Alcohol intake frequency.	1.8	4.1	7.3	2.6	1.9	1.8	2.3	1.4	2.1	1.8	2.1	0.4	2.3	2.1	2.7	2.1	2.2	1.9	2.0	2.3	1.8	2.3	2.0	2.6	0.4	2.2	1.2
Mineral and other dietary supplements	1.8	2.5	6.2	-1.9	-1.6	-2.5	-1.1	-0.2	-1.1	-1.6	-1.7	0.1	-1.9	-1.5	-1.9	-1.7	-1.3	-1.8	-1.8	-1.4	-1.1	-1.5	-1.5	-1.4	-1.9	-1.6	-1.6
Pain type(s) experienced in last month: Hip pain	1.8	2.3	7.7	-1.0	-2.1	-0.5	-1.9	-2.8	-1.5	-0.6	-1.2	-2.4	-1.2	-0.9	-1.4	-0.2	-2.1	-1.6	-1.6	-1.8	-1.4	-1.8	-1.2	-0.7	-0.7	-1.6	-1.2
Arm fat-free mass (left)	1.8	9.1	15.7	-3.1	-3.0	-4.0	-3.2	-3.3	-1.3	-2.3	-3.0	-0.1	-3.3	-3.0	-2.6	-3.2	-3.5	-3.4	-3.6	-3.0	-3.7	-3.6	-2.6	-3.1	-2.7	-3.0	-2.4
Bipolar Disorder (2018)	1.7	2.7	5.9	1.6	1.4	1.5	1.9	2.4	0.7	1.8	1.6	-0.1	1.6	1.1	2.0	1.7	2.1	1.9	1.9	1.7	1.9	1.9	2.2	0.9	1.5	1.7	0.7
Ever had hysterectomy (womb removed)	1.7	2.0	6.2	1.8	1.2	1.6	1.1	0.7	1.7	1.1	1.5	-0.4	1.7	1.3	1.6	2.5	1.4	1.4	1.4	0.6	1.0	1.2	2.0	1.3	0.9	1.2	1.3
Diabetes (mother)	1.7	2.2	5.0	-1.1	-1.9	-2.2	-1.2	-1.3	-0.9	-1.5	-1.2	-1.5	-1.3	-1.2	-1.3	-2.1	-1.4	-1.8	-1.9	-1.5	-1.2	-1.4	-1.6	-0.7	-2.2	-1.3	-0.5
Body mass index (BMI)	1.7	7.3	16.5	1.0	3.5	1.5	2.7	3.4	3.5	1.8	2.0	-1.2	1.5	4.1	3.2	3.0	2.6	2.1	3.1	1.9	1.8	2.5	3.1	3.9	2.3	3.9	1.7
Trunk fat mass	1.7	7.1	11.9	-3.2	-2.7	-3.5	-3.1	-2.0	-1.8	-2.9	-2.8	-2.3	-3.2	-1.6	-2.2	-2.7	-2.9	-3.4	-2.7	-2.7	-3.1	-3.1	-2.5	-1.6	-2.8	-2.0	-2.1
Exposure to tobacco smoke at home	1.7	1.9	7.3	-2.5	-1.0	-1.6	-1.4	0.1	-0.3	-2.7	-2.3	-0.7	-2.3	-1.1	-0.6	-1.2	-1.5	-1.9	-1.4	-0.7	-0.6	-1.4	-0.2	-0.2	-0.4	-0.8	-0.6
Schizophrenia (2018)	1.6	3.4	6.6	1.8	1.8	1.7	2.0	1.0	2.0	1.5	1.7	0.9	1.7	2.1	2.3	2.3	1.6	2.0	1.8	1.2	2.0	1.9	2.5	1.2	2.6	2.2	1.4
Alzheimer’s Disease (in mother)	1.6	1.8	3.3	1.2	1.5	0.5	1.6	1.3	1.6	1.6	1.4	-1.6	1.1	1.8	1.5	1.6	1.5	1.2	1.2	0.4	0.6	1.5	1.2	1.2	1.3	1.7	1.1
Heel T-Score	1.6	12.4	17.4	3.5	3.7	4.2	3.6	2.6	2.8	3.4	3.9	-0.2	3.7	4.1	3.3	4.0	3.5	3.8	3.8	3.2	3.5	3.7	3.5	4.1	3.2	4.1	2.9
Leg fat-free mass (left)	1.6	8.2	15.6	-2.9	-2.8	-3.8	-2.8	-3.1	-1.5	-2.2	-2.6	0.4	-3.0	-2.6	-2.4	-3.2	-3.1	-3.1	-3.2	-2.7	-4.0	-3.4	-2.8	-3.2	-2.4	-2.6	-3.0
Medication: Seretide 50 evohaler	1.6	1.8	4.5	-1.2	-1.1	-0.8	-1.7	-2.1	-1.1	-1.0	-1.5	-0.0	-1.4	-1.6	-0.8	-1.4	-1.8	-1.7	-1.7	-1.3	-1.7	-1.9	-0.3	-1.1	-0.1	-1.7	-0.0
Had major operations	1.6	1.9	4.0	-1.0	-1.9	-1.1	-1.4	-2.0	-0.9	-1.0	-0.9	0.3	-1.1	-1.3	-1.2	-1.1	-1.7	-1.3	-1.8	-1.4	-1.2	-1.7	-1.4	-1.7	-1.9	-1.7	-0.3
Supplements: Vitamin C	1.6	1.9	5.4	2.3	0.8	1.3	1.2	-0.3	-0.0	2.1	2.1	0.4	2.3	1.2	1.1	0.3	1.5	1.9	1.8	1.5	-0.0	1.7	0.4	0.1	1.5	1.2	0.5
Commuting to job workplace: Cycle	1.6	2.0	5.7	-0.9	-1.6	-1.9	-1.6	-1.0	-1.1	-0.9	-1.1	1.5	-1.0	-1.3	-1.3	-2.2	-1.0	-1.3	-0.9	-1.1	-2.2	-1.2	-1.4	-2.4	-1.5	-0.9	-0.7
Age when periods started (menarche)	1.5	3.7	6.5	-2.2	-1.7	-2.1	-2.4	-1.6	-1.6	-2.1	-2.5	0.1	-2.2	-2.5	-2.1	-2.0	-2.1	-1.8	-2.0	-0.8	-2.0	-2.1	-1.4	-1.8	-0.6	-2.6	-1.5
Leg predicted mass (left)	1.5	8.1	15.6	-2.9	-2.8	-3.8	-2.7	-3.1	-1.5	-2.2	-2.5	0.3	-2.9	-2.6	-2.4	-3.2	-3.1	-3.0	-3.2	-2.8	-4.0	-3.3	-2.9	-3.2	-2.4	-2.6	-3.0
Medication: Paracetamol	1.5	2.4	6.0	-1.5	-1.1	-1.7	-1.3	-2.4	-0.8	-1.9	-1.7	0.4	-1.8	-1.2	-1.2	-1.8	-2.2	-1.6	-1.8	-1.1	-1.8	-1.8	-1.3	-1.1	-1.9	-1.2	-0.1
Risk taking	1.5	2.3	5.5	-2.2	-1.9	-1.8	-2.2	-0.4	-0.3	-2.0	-2.3	-1.2	-2.2	-1.4	-0.3	-0.2	-1.8	-2.1	-2.1	-1.0	-0.4	-2.0	-0.8	-0.4	-0.3	-1.2	-0.3
Cholesterol lowering medication	1.5	2.2	5.7	-1.3	-2.0	-1.9	-1.1	-0.6	-1.9	-1.2	-1.5	-0.7	-1.3	-1.5	-1.6	-1.6	-1.1	-1.7	-1.5	-2.4	-1.4	-1.3	-1.2	-1.0	-2.0	-1.4	-0.6
Average weekly spirits intake	1.4	1.7	4.8	-1.5	-0.6	-0.5	-0.5	-1.8	-1.9	-2.2	-0.8	1.9	-1.5	-0.6	-0.4	-0.8	-1.8	-1.1	-1.7	-1.9	-1.3	-1.5	-0.9	-0.2	-1.1	-0.8	-0.8
Illnesses of siblings	1.4	1.9	3.5	1.1	1.6	0.5	1.2	0.9	1.5	1.3	1.4	1.3	1.4	1.4	1.2	0.8	1.4	1.8	1.9	1.8	0.4	1.4	1.3	0.6	1.9	1.7	1.8
Length of working week for main job	1.4	1.6	5.0	-0.0	1.4	0.5	1.3	1.3	2.2	0.3	0.2	0.1	0.1	1.9	1.8	1.8	0.7	0.7	1.0	1.5	1.3	0.9	1.2	2.0	1.3	1.8	0.5
Pulse rate, automated reading	1.4	4.5	6.7	2.4	2.2	2.6	2.3	1.2	2.5	2.3	2.4	-0.5	2.4	2.4	2.2	2.2	2.1	2.5	2.5	1.7	1.7	2.1	2.1	2.1	1.6	2.1	1.6
Medication: Aspirin	1.4	1.8	4.7	0.6	1.8	1.2	1.2	1.7	1.5	0.4	0.7	-0.8	0.6	1.8	1.7	1.8	1.1	0.8	1.3	0.7	1.5	1.3	1.9	2.2	1.1	1.7	0.5
Financial situation satisfaction	1.4	1.7	8.1	0.4	1.8	0.3	1.6	1.8	2.8	0.1	0.7	-0.2	0.5	1.6	2.0	1.4	1.2	0.9	1.1	0.8	1.2	1.3	0.6	1.9	0.3	1.4	0.6
Depression (Nagel 2018)	1.3	2.0	5.8	0.2	1.7	0.5	1.5	0.8	2.4	1.0	0.6	-1.7	0.3	1.8	1.9	1.4	0.7	0.8	0.7	-0.5	1.0	1.0	2.2	1.5	1.4	1.8	2.4
Ulcerative Colitis (UC)	1.3	2.5	4.9	-1.2	-1.8	-1.9	-1.7	-1.1	-0.5	-1.4	-1.9	-1.1	-1.5	-2.2	-1.7	-1.4	-1.6	-1.9	-1.8	-2.0	-0.9	-1.7	-0.9	-1.9	-1.4	-2.1	-0.5
Angina	1.3	1.7	8.5	-0.6	1.3	0.8	1.2	2.0	2.1	-0.4	-0.2	-2.9	-0.4	1.4	0.9	1.2	0.5	-0.2	0.5	-0.3	1.8	0.7	1.2	2.6	0.4	1.0	1.0
Vitamin and mineral supplements	1.3	1.7	4.2	-1.1	-1.5	-1.9	-1.0	-0.1	-1.5	-1.3	-1.2	0.8	-1.2	-1.6	-1.1	-0.8	-0.9	-1.5	-1.4	-1.0	-0.9	-1.1	-0.8	-2.1	-1.8	-1.6	-1.6
Alcohol usually taken with meals	1.3	2.1	5.8	-1.0	-1.8	-1.2	-2.4	-1.3	-1.4	-0.9	-1.1	0.4	-1.0	-1.6	-1.9	-0.5	-1.3	-1.4	-1.4	-1.7	-1.5	-1.9	-1.6	-2.2	-0.7	-1.8	-1.0
Mouth/teeth dental problems: Loose teeth	1.3	1.5	3.3	0.3	1.3	0.9	1.3	1.8	0.5	0.4	0.8	-0.6	0.5	1.3	1.5	1.4	1.1	1.3	1.4	1.6	0.7	1.1	1.8	1.7	1.3	1.8	1.2
Fractured/broken bones in last 5 years	1.3	1.7	4.7	1.2	1.1	0.8	1.4	1.9	1.0	1.5	0.7	-0.6	1.2	0.6	1.7	0.9	1.6	1.3	1.4	1.1	1.7	1.6	1.5	0.3	2.2	1.0	0.4
Ever depressed for a whole week	1.3	1.6	5.5	0.9	1.4	2.4	1.1	0.0	0.9	1.3	1.6	0.7	1.1	1.5	1.6	1.9	0.7	1.3	1.1	0.6	0.6	0.6	1.6	1.2	1.7	1.4	0.1
Qualifications: CSEs or equivalent	1.2	1.6	3.5	-1.4	-0.9	-1.1	-1.3	-1.9	0.4	-1.0	-1.2	1.6	-1.3	-1.3	-1.5	-0.8	-1.6	-0.9	-1.3	-0.7	-1.8	-1.7	-1.1	-0.9	-1.1	-1.0	-0.9
Number of full brothers	1.2	1.5	3.3	0.9	1.1	0.5	1.2	1.7	1.6	0.7	0.6	0.8	0.9	1.1	1.4	1.1	1.4	0.8	1.1	1.1	1.6	1.4	1.2	1.8	0.9	1.1	1.8
Medication: Blood pressure	1.2	2.2	7.2	0.7	1.7	1.3	1.7	2.7	2.1	1.1	0.9	-0.0	0.7	1.7	0.9	1.4	1.5	1.1	1.4	0.9	2.5	1.5	1.3	2.2	-0.4	1.5	0.9
Leg fat-free mass (right)	1.2	6.6	13.4	-2.5	-2.4	-3.3	-2.3	-3.0	-1.2	-1.9	-2.1	0.3	-2.6	-2.3	-2.1	-2.8	-2.8	-2.7	-2.9	-2.6	-3.7	-3.0	-2.6	-2.8	-2.3	-2.3	-2.9
Leg predicted mass (right)	1.2	6.3	13.0	-2.5	-2.4	-3.2	-2.3	-2.9	-1.2	-1.9	-2.1	0.3	-2.5	-2.3	-2.0	-2.8	-2.8	-2.6	-2.9	-2.5	-3.6	-3.0	-2.6	-2.8	-2.2	-2.3	-2.9
Medication: Bendroflumethiazide	1.2	1.8	4.6	1.1	1.7	-0.1	1.4	2.2	1.8	1.6	1.1	0.6	1.1	1.9	1.2	0.2	1.8	1.1	1.7	0.1	1.2	1.8	1.1	1.7	0.2	1.6	1.3
Reaction Time	1.1	2.0	5.3	1.4	1.9	1.3	1.2	1.1	1.2	1.5	1.2	1.9	1.5	0.8	1.5	1.4	1.5	1.7	1.6	2.3	1.1	1.6	1.2	0.6	1.8	0.9	0.6
Bipolar Disorder (2011)	1.1	1.1	3.6	1.2	0.4	1.2	1.4	1.2	-0.1	1.1	1.2	-1.0	1.3	0.5	1.9	0.8	1.4	1.3	1.1	-0.0	0.9	1.3	0.9	-0.0	1.1	1.0	-0.1
Neuroticism (2016)	1.1	1.5	3.8	0.6	1.7	1.1	1.2	1.7	1.1	-0.1	0.6	-1.0	0.8	1.1	0.5	1.2	1.2	1.3	1.5	0.5	1.5	1.3	2.0	1.7	1.6	1.1	1.2
Ulcerative Colitis	1.1	1.6	3.1	-0.8	-1.8	-1.1	-1.3	-1.1	-0.2	-1.1	-1.4	-1.2	-1.1	-1.7	-1.0	-0.9	-1.2	-1.5	-1.6	-1.7	-0.6	-1.3	-1.1	-1.5	-1.3	-1.6	-1.2
Medication for hormone replacement therapy	1.1	1.2	3.8	-1.0	-1.4	-1.3	-1.7	-0.5	-0.4	-1.3	-1.5	-0.5	-1.3	-1.1	-1.4	-0.7	-1.1	-1.4	-1.1	-0.4	-0.4	-1.2	-0.6	-0.6	-1.9	-1.3	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	7.0	-0.3	1.3	0.1	0.5	0.7	2.6	-0.0	-0.1	-1.4	-0.1	1.4	1.3	0.8	0.2	0.3	0.4	-0.2	1.4	0.6	2.1	1.9	1.0	1.2	2.2
Prospective memory result	1.1	1.4	4.1	1.2	1.5	1.4	1.4	0.9	1.4	0.7	1.1	1.9	1.2	1.1	0.5	0.3	1.2	1.5	1.3	2.0	0.4	1.1	0.8	1.2	0.6	1.2	0.9
Eye problems/disorders: None of the above	1.1	1.3	4.5	1.3	0.6	0.6	0.8	2.0	0.8	1.5	0.7	-1.7	1.3	0.5	-0.1	0.3	1.7	0.9	1.3	1.4	2.1	1.7	0.2	0.7	0.1	0.4	0.5
Emphysema/chronic bronchitis	1.1	1.3	3.5	-1.9	-0.6	-0.4	-1.5	-0.9	-0.3	-1.2	-1.7	-0.1	-1.8	-0.9	-0.5	-0.4	-1.6	-1.3	-1.2	-1.7	-1.1	-1.6	0.6	-0.3	-0.3	-1.1	0.4
Ever smoked	1.1	2.0	7.3	-2.7	-1.2	-1.1	-1.2	0.6	-0.5	-1.5	-2.3	-1.2	-2.5	-0.7	-1.5	-0.9	-1.7	-2.2	-2.0	0.1	0.5	-1.7	-0.3	0.8	-0.6	-1.1	-0.3
Supplements: Calcium	1.1	1.2	2.7	1.5	1.3	1.1	0.9	1.2	0.7	1.1	1.1	0.4	1.5	0.9	0.9	0.8	1.6	1.3	1.6	1.0	0.6	1.3	1.0	0.6	0.8	0.8	1.1
Age at First Birth	1.0	1.4	3.0	1.5	1.1	1.2	1.4	1.1	1.2	1.3	1.7	-0.6	1.4	1.7	0.4	0.7	1.4	1.2	1.2	0.5	1.5	1.4	0.5	1.1	-0.6	1.4	0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	6.1	0.5	2.1	2.5	1.7	1.2	1.6	1.2	1.4	-1.1	0.7	1.4	1.9	2.2	0.9	1.6	1.1	0.0	2.1	1.2	1.0	1.8	1.3	2.0	0.8
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.4	5.8	1.2	1.8	2.4	1.4	1.0	1.2	1.6	1.9	-0.6	1.4	1.4	1.9	2.1	1.2	1.8	1.4	0.6	1.9	1.3	1.6	1.5	1.2	2.2	1.2
Chest pain or discomfort	1.0	1.5	5.1	0.1	1.1	0.2	1.2	1.9	2.3	0.7	0.0	-1.9	0.2	1.1	2.1	0.8	0.9	0.6	0.8	1.0	1.8	1.1	1.2	1.7	0.8	1.3	0.6
Qualifications: nursing, teaching	1.0	1.6	3.7	-1.4	-1.5	-1.7	-1.9	-0.9	-1.3	-0.7	-1.5	-0.1	-1.4	-1.1	-1.1	-0.5	-1.3	-1.6	-1.3	-0.4	-1.5	-1.5	-0.8	-1.8	0.0	-1.1	-0.7
High cholesterol (Self-reported)	1.0	1.8	4.6	-1.9	-1.4	-1.4	-1.2	0.4	-0.3	-1.9	-2.1	-1.4	-1.8	-1.2	-1.5	-1.2	-1.2	-1.9	-1.2	-1.4	-0.0	-1.2	-1.1	-0.4	-1.7	-1.2	-0.9
Illnesses of father: High blood pressure	1.0	1.2	6.2	-0.6	-0.8	-1.1	-0.4	-0.3	-0.5	-0.4	-0.9	-1.6	-0.8	-1.6	-0.8	0.0	-0.6	-0.8	-1.1	-1.1	-0.3	-0.6	-1.9	-1.6	-0.8	-1.5	-2.5
Coronary Artery Disease (CAD)	0.9	1.1	2.2	1.0	1.2	1.4	0.9	1.2	0.6	1.0	0.9	-0.5	1.0	0.7	1.3	1.3	1.2	0.9	1.2	1.1	0.5	1.0	1.5	0.9	1.2	0.9	0.7
Supplements: Zinc	0.9	1.0	1.9	-1.3	-0.6	-1.2	-1.1	-0.8	-1.2	-1.3	-1.0	0.8	-1.1	-0.5	-1.2	-1.3	-1.1	-0.8	-0.6	-0.9	-1.4	-1.0	-0.9	-0.6	0.0	-0.8	-0.5
Trunk fat percentage	0.9	3.8	7.5	-2.6	-1.9	-2.6	-2.3	-0.8	-1.4	-2.4	-2.1	-2.7	-2.4	-0.6	-1.5	-1.9	-1.9	-2.6	-1.7	-1.7	-2.1	-2.1	-1.9	-0.6	-2.1	-1.0	-1.4
Chronic bronchitis/emphysema (father)	0.9	1.1	5.3	-1.4	-0.9	-1.1	-0.7	-0.4	-0.5	-2.3	-1.0	-0.5	-1.5	-0.2	-0.7	-0.3	-1.2	-1.1	-1.0	-0.9	-0.5	-1.1	-1.3	-0.5	-1.7	-0.5	-0.5
Hair/balding pattern: Pattern 2	0.9	1.1	4.8	-1.3	-0.9	-0.9	-1.1	-0.4	-0.6	-0.8	-1.4	-0.0	-1.4	-0.9	-1.2	-0.8	-1.2	-1.3	-1.3	-0.7	0.0	-1.2	-1.1	-0.9	-2.2	-1.0	-0.7
Birth weight	0.9	1.9	5.2	-1.2	-1.6	-1.0	-1.8	-0.8	-1.5	-0.2	-1.5	-0.2	-1.2	-1.4	-2.3	-1.9	-1.2	-1.6	-1.3	-1.4	-0.9	-1.4	-1.8	-0.8	-1.6	-1.6	-1.0
Angina (self-reported)	0.9	1.2	7.8	-0.6	1.0	0.6	1.0	1.7	1.7	-0.3	-0.3	-2.8	-0.4	1.1	0.7	1.0	0.4	-0.3	0.3	-0.3	1.4	0.5	0.9	2.2	0.1	0.7	0.8
Whole body fat mass	0.9	3.6	7.1	-2.6	-1.6	-2.7	-2.2	-1.1	-0.9	-2.1	-2.1	-2.0	-2.5	-0.7	-1.4	-1.9	-2.1	-2.5	-1.8	-1.8	-2.3	-2.2	-1.6	-0.7	-2.1	-1.0	-1.5
Osteoporosis (self-reported)	0.9	1.1	2.9	-0.9	-0.8	-0.2	-1.1	-1.3	-1.7	-0.9	-1.1	-0.5	-1.0	-1.0	-1.1	-0.8	-1.2	-1.1	-1.1	-0.5	-1.2	-1.1	-0.4	-1.4	-1.3	-1.0	-1.7
Pack years of smoking	0.9	1.3	5.9	-0.1	1.4	0.2	1.1	0.7	1.7	-0.1	0.3	-0.2	-0.1	1.5	2.4	1.3	0.4	0.1	0.4	0.4	0.4	0.5	2.4	2.1	0.8	1.4	1.3
Breast Cancer	0.8	1.9	4.2	1.1	1.7	1.5	1.3	1.5	1.0	0.8	1.3	-0.3	1.3	1.4	1.7	2.0	1.4	1.5	1.4	0.4	1.2	1.4	1.9	1.4	0.8	1.5	1.3
Fasting Glucose	0.8	1.0	3.7	-0.3	0.9	1.0	0.7	0.6	1.5	0.4	0.2	0.5	-0.1	1.1	0.9	1.8	0.1	0.3	0.3	0.5	1.3	0.4	0.8	1.8	1.1	0.8	1.9
Serious illness, injury or assault to yourself	0.8	0.9	2.7	-0.7	-1.6	-0.8	-0.9	-1.0	-0.0	-1.0	-0.8	-0.5	-1.1	-0.7	-0.5	-0.7	-1.2	-1.1	-1.6	-1.2	-0.5	-1.3	-0.7	-0.3	-1.1	-0.8	-1.2
Past tobacco smoking	0.8	1.5	5.0	2.2	1.1	0.6	1.2	-0.0	0.8	1.6	2.0	0.2	2.2	1.1	1.0	0.8	1.6	1.8	1.9	0.2	-0.3	1.5	0.3	-0.4	0.5	1.1	0.4
Qualifications: None of the above	0.8	1.6	7.6	0.9	1.2	0.9	0.5	0.8	1.1	0.9	0.6	0.1	1.0	1.6	1.1	1.2	0.9	0.9	1.3	0.8	1.0	1.0	2.5	2.3	0.1	1.3	2.8
Worrier / anxious feelings	0.8	1.6	3.1	1.3	1.5	1.0	1.5	1.6	1.6	0.7	1.2	0.3	1.4	1.1	0.5	1.3	1.6	1.4	1.8	0.8	1.3	1.7	1.6	1.0	0.5	1.1	0.9
Loud music exposure frequency	0.8	0.9	2.2	1.1	0.9	1.2	1.5	0.8	0.3	0.9	1.2	-1.0	1.2	0.1	1.1	0.8	1.1	1.4	1.0	0.6	1.0	1.1	0.2	0.1	0.9	0.7	-0.9
Medication: Amlodipine	0.8	1.1	3.2	-1.3	-1.1	-0.6	-1.3	-0.1	-0.8	-1.5	-1.8	0.6	-1.4	-1.3	-0.9	-0.9	-1.2	-1.3	-1.1	0.1	0.2	-1.2	-0.4	-0.5	-0.9	-1.1	-0.9
Knee pain experienced in last month	0.8	1.2	4.0	2.0	0.3	0.7	1.1	-0.7	0.5	1.6	1.3	2.0	1.7	0.5	1.6	0.3	1.0	1.2	0.7	0.8	-0.2	0.9	1.0	0.2	0.9	0.6	1.5
Medication for cholesterol	0.8	1.1	3.2	1.0	1.0	1.7	1.3	0.7	1.1	1.0	1.4	-0.8	1.1	0.9	1.3	1.7	0.9	1.2	0.6	0.3	1.8	1.1	0.5	0.7	1.0	0.9	-0.1
Medication: Aspirin	0.8	1.1	3.4	0.2	1.3	1.0	0.8	1.4	1.1	0.1	0.4	-0.6	0.3	1.5	1.1	1.5	0.7	0.4	1.0	0.3	1.3	0.9	1.5	1.8	1.0	1.3	0.5
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.2	-1.5	-0.9	-1.2	-1.4	-0.9	-0.5	-1.4	-1.3	-1.0	-1.4	-0.3	-0.8	-0.3	-1.4	-1.3	-0.8	0.3	-1.3	-1.3	0.5	-0.2	-1.0	-0.3	0.6
HbA1C	0.7	0.8	2.0	0.8	1.3	1.0	0.7	0.5	1.4	1.0	0.8	-0.2	0.8	0.8	0.8	1.0	0.8	0.8	1.2	0.8	0.2	0.9	0.9	1.4	0.4	0.9	0.3
Severe depression (siblings)	0.7	0.8	3.1	0.7	0.5	0.8	1.0	0.2	1.1	0.5	1.0	1.1	0.8	1.4	0.5	1.8	0.6	0.6	0.6	0.6	1.2	0.9	0.2	1.7	-0.1	0.7	0.5
Townsend deprivation index at recruitment	0.7	1.0	4.1	0.2	1.0	0.5	0.4	1.0	1.8	0.6	0.4	0.1	0.4	1.1	0.9	0.8	0.7	0.6	0.9	2.0	0.6	0.7	1.5	1.5	1.1	1.2	0.6
Supplements: Glucosamine	0.7	0.9	2.8	0.7	1.2	1.7	0.6	0.7	0.7	0.9	0.9	0.9	0.9	0.6	0.8	0.3	0.9	1.4	1.3	0.7	0.6	0.7	0.9	0.6	1.2	0.8	1.4
High blood pressure (mother)	0.7	1.0	2.8	1.4	0.5	1.7	1.2	0.5	-0.3	1.4	1.0	-0.2	1.4	-0.8	1.4	1.0	1.1	1.1	0.6	0.1	1.2	1.0	0.7	-0.5	0.4	0.1	-1.2
Number of incorrect matches in round	0.7	1.1	6.2	0.4	-1.6	-0.9	-0.3	0.1	-1.4	0.2	-0.7	-0.9	0.2	-2.1	-0.7	-1.2	0.2	-0.7	-0.7	0.1	-0.4	-0.3	-1.5	-2.5	-0.2	-1.6	-0.9
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.8	-0.2	1.2	0.3	0.5	1.8	1.0	-0.5	-0.0	0.1	-0.1	1.0	1.0	2.0	0.7	0.3	0.7	-0.4	1.2	0.6	1.6	1.3	0.7	0.9	0.5
Falls in the last year	0.7	1.0	6.5	0.2	0.9	0.6	1.1	0.7	2.5	0.1	0.6	-0.7	0.1	1.5	1.7	1.2	0.5	0.3	0.4	1.0	0.4	0.4	1.0	1.4	0.4	1.3	0.3
Medication: Cholesterol lowering	0.7	1.0	3.6	-0.3	1.3	1.0	1.0	1.9	1.3	-0.1	0.2	-1.1	-0.0	1.4	0.3	0.7	0.7	0.4	1.1	0.7	1.6	0.9	0.8	1.8	0.5	1.1	0.6
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	5.4	0.0	-1.1	-0.7	-0.9	-2.3	-1.8	-0.1	-0.1	0.9	-0.1	-1.1	-0.4	-1.1	-0.9	-0.3	-0.9	-0.8	-1.9	-0.9	-1.2	-1.8	0.4	-1.0	-0.7
Medication for pain relief, constipation, heartburn	0.7	1.2	3.6	-0.5	-1.3	-0.2	-1.0	-0.5	-1.4	-0.4	-0.7	0.9	-0.4	-1.9	-1.8	-1.1	-0.6	-0.4	-0.6	-0.6	-0.6	-0.8	-1.6	-1.9	-0.0	-1.7	-1.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.1	0.5	-1.2	-1.3	-0.6	-1.8	-1.7	0.5	-0.2	0.5	0.1	-0.6	-0.3	-0.7	-0.6	-0.4	-0.8	-0.5	-1.0	-0.5	-0.6	-1.6	-0.2	-0.7	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.4	-0.8	-1.0	-0.9	-0.9	-1.2	-0.4	-0.7	-0.5	-1.4	-0.7	-0.6	-0.0	-0.1	-0.9	-0.7	-0.7	-1.6	-0.8	-0.7	-1.2	-0.8	-0.3	-0.4	-1.4
Wears glasses or contact lenses	0.7	0.8	3.2	0.1	0.9	0.2	0.4	0.6	1.0	0.6	0.5	1.1	0.2	1.8	0.7	0.2	0.4	0.2	0.6	1.1	0.3	0.3	1.4	1.5	-0.2	1.4	1.6
Ever taken oral contraceptive pill	0.7	0.7	2.3	1.1	0.9	1.5	0.7	0.3	-0.1	1.5	1.0	0.4	1.0	0.5	0.2	0.9	0.8	1.4	1.2	0.3	0.7	0.9	0.4	-0.2	1.2	0.5	-0.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.5	1.0	0.7	1.4	0.7	0.8	-0.2	1.4	0.9	0.4	1.1	0.3	0.1	0.4	0.9	1.1	1.5	1.6	0.7	0.9	0.3	-0.3	0.8	0.6	-0.4
Eye problems/disorders: Glaucoma	0.7	0.8	2.3	-0.1	1.3	0.7	1.3	1.0	0.8	0.1	0.3	1.3	-0.0	1.0	1.4	0.9	0.5	0.3	0.3	1.2	0.6	0.5	1.5	1.4	0.7	1.1	0.7
Medication: Atorvastatin	0.7	0.8	3.2	-1.8	-0.1	-1.2	-0.5	1.3	0.7	-1.2	-1.6	-1.5	-1.6	0.0	-0.7	0.0	-0.5	-1.3	-0.6	-0.9	0.5	-0.5	-0.4	0.5	-0.5	-0.2	-0.3
Medication: Co-codamol	0.6	0.7	2.9	1.0	0.6	0.9	0.6	-0.4	1.1	0.6	0.7	-0.6	0.9	0.8	0.9	0.6	0.5	0.5	0.5	-0.0	0.7	0.6	0.9	1.3	-0.5	0.8	1.7
Pack years adult smoking proportion	0.6	1.0	5.1	-0.3	1.3	0.1	1.0	0.5	1.6	-0.2	0.1	-0.1	-0.2	1.1	2.3	1.0	0.2	0.1	0.2	0.2	0.3	0.3	2.1	1.7	1.0	1.1	1.0
Maternal smoking around birth	0.6	0.9	3.4	-1.5	-0.4	-0.5	-0.6	-0.2	-0.7	-1.1	-1.2	-1.2	-1.3	-0.6	0.6	-0.3	-0.9	-0.7	-0.4	-1.9	-0.9	-0.8	-0.2	-0.9	1.1	-0.5	-1.1
Multivitamins +/- minerals	0.6	0.8	2.1	0.4	1.4	0.9	0.6	0.5	1.0	0.9	0.6	-0.7	0.6	1.0	1.1	0.5	0.7	0.9	0.9	0.5	0.4	0.7	0.5	1.4	1.4	1.2	1.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	4.1	0.4	1.1	1.4	0.6	-0.1	1.0	0.5	0.7	1.1	0.4	1.1	1.2	0.7	0.2	0.8	0.6	0.0	-0.1	0.2	2.0	0.8	1.3	1.2	-0.3
Financial difficulties in last 2 years	0.6	0.8	4.8	0.4	0.7	-0.4	0.6	0.6	2.2	0.6	0.2	-0.1	0.3	1.3	1.1	1.0	0.5	0.5	0.7	1.4	0.3	0.7	1.0	0.5	0.8	1.5	0.7
Medication: Lansoprazole	0.6	0.6	2.4	1.0	0.3	0.8	0.8	0.2	0.3	0.8	1.0	0.3	0.9	1.3	0.6	1.6	0.6	0.8	1.0	0.4	0.7	0.8	0.7	0.6	-0.4	1.1	0.3
Tense / ‘highly strung’	0.6	0.9	5.2	0.4	1.2	0.9	0.4	0.7	1.2	0.0	0.3	0.7	0.4	1.1	-0.1	0.9	0.5	0.8	0.9	1.1	1.1	0.7	1.4	1.4	0.8	0.7	2.3
Wheeze or whistling in the chest in last year	0.6	1.1	3.4	1.0	0.6	-0.0	1.3	1.1	0.6	0.8	1.2	-1.8	0.9	1.5	1.6	0.5	1.3	0.6	0.7	-1.1	0.1	1.0	1.2	1.1	-0.5	1.4	0.9
Guilty feelings	0.6	0.9	3.0	0.0	1.3	0.7	0.6	1.7	1.0	0.0	-0.1	-1.2	-0.0	1.1	1.1	0.6	0.7	0.5	0.9	0.7	1.2	0.6	1.6	1.2	1.4	0.9	-0.1
Alcohol drinker status: Never	0.6	0.7	2.5	0.4	0.9	0.7	0.8	1.2	1.6	0.2	0.6	-0.5	0.5	1.0	1.2	0.9	0.8	0.3	0.6	0.1	1.0	0.8	0.8	1.4	0.0	1.1	-0.2
Depressed Affect (Nagel 2018)	0.5	1.0	3.8	0.2	1.5	0.3	1.1	0.3	1.4	0.9	0.4	-0.9	0.3	1.6	1.0	0.5	0.4	0.7	0.5	0.0	0.4	0.6	1.9	1.4	-0.3	1.4	2.0
Type 2 Diabetes (T2D) (2012)	0.5	0.6	5.0	0.2	-1.1	-0.4	-0.6	-0.6	-2.2	0.2	0.0	-0.9	0.1	-0.4	-0.7	-0.2	-0.3	-0.0	-0.4	-0.2	-0.6	-0.4	-1.2	-0.8	-0.4	-0.6	-1.7
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.1	-0.7	-0.6	-0.6	-1.0	1.2	0.0	-0.8	-1.1	-1.4	-0.9	0.3	-0.8	0.7	-0.3	-1.0	-0.2	0.0	1.0	-0.4	0.1	0.4	-1.5	-0.3	0.6
Current tobacco smoking	0.5	0.8	1.7	-1.3	-1.2	-1.0	-0.7	-0.5	0.1	-0.7	-0.8	-1.1	-1.3	-0.0	-0.6	-0.2	-1.1	-1.0	-1.2	-0.7	-0.6	-1.1	-0.9	-0.3	-1.2	-0.3	-0.9
Had other major operations	0.5	0.7	2.6	1.2	-0.2	0.2	0.5	0.1	0.0	1.1	1.2	-0.3	1.2	1.4	0.6	1.6	0.8	0.8	0.9	-0.0	0.6	1.0	-0.2	0.1	0.3	1.0	-0.4
Father’s age at death	0.5	0.7	2.0	-1.0	0.1	-0.3	-1.0	-0.3	0.4	-1.4	-0.9	0.4	-1.1	-0.2	-1.2	-1.1	-0.9	-1.4	-0.7	0.4	-0.7	-1.0	0.6	0.3	-1.1	-0.7	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.7	4.0	-1.5	0.3	-0.9	-0.2	0.2	2.0	-0.7	-1.3	-1.4	-1.3	0.5	0.5	-0.3	-0.8	-0.9	-0.6	0.2	0.1	-0.4	0.8	0.8	0.5	0.6	-0.3
Noisy workplace	0.5	0.6	1.6	0.8	0.5	0.3	0.7	0.8	1.1	0.3	0.7	-0.5	0.7	0.7	1.1	0.8	0.9	0.6	0.7	1.3	0.5	0.8	0.6	1.1	0.6	0.6	0.8
Depression (self-reported)	0.5	0.6	2.8	-0.5	-0.6	-0.7	-0.4	-0.4	0.1	-1.1	-0.6	-0.7	-0.7	-0.1	-1.1	-0.3	-0.6	-0.8	-0.8	-1.3	0.2	-0.6	-0.9	0.4	-1.7	-0.7	0.7
Pulse wave Arterial Stiffness index	0.5	0.6	1.5	-1.0	-0.7	-0.0	-0.9	-0.9	-0.7	-1.0	-0.7	-1.2	-1.0	-0.4	-0.5	-0.0	-1.1	-0.8	-0.9	-1.1	-0.4	-1.1	0.2	-0.3	-0.5	-0.6	-0.0
Breastfed as a baby	0.5	0.6	3.8	-0.6	-0.9	-1.2	-0.6	-0.3	0.0	-0.8	-0.7	-0.1	-0.8	0.4	-1.1	0.1	-0.7	-1.1	-0.8	-0.0	0.2	-0.6	-0.4	0.7	-2.0	-0.5	0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	4.1	0.3	-0.4	0.3	-0.2	-0.2	-1.7	0.5	0.1	-0.4	0.3	-0.8	0.0	-0.5	0.1	0.3	0.2	-0.3	-1.1	-0.2	-0.3	-2.0	1.4	-0.3	-1.1
Medication: Paracetamol	0.5	0.8	3.3	-0.6	-0.6	-1.0	-0.6	-1.8	-0.3	-1.2	-0.9	0.4	-0.9	-0.3	-0.3	-0.9	-1.3	-1.0	-1.1	-1.2	-1.1	-1.0	-0.5	-0.3	-1.5	-0.3	-0.2
Comparative body size at age 10	0.5	1.4	3.3	1.1	1.1	-0.0	1.6	1.8	1.2	1.8	1.1	-0.2	1.1	1.1	1.2	0.7	1.6	1.2	1.3	1.4	0.6	1.4	0.8	0.4	1.6	1.1	0.6
Worry too long after embarrassment	0.5	0.8	3.6	0.9	0.7	0.2	1.1	1.7	0.2	0.4	0.7	-1.9	0.9	0.5	1.0	0.2	1.4	0.9	0.9	-0.2	1.1	1.3	0.9	0.3	0.5	0.7	-0.5
Migraine (self-reported)	0.5	0.7	2.6	-0.4	-0.6	-0.9	-0.6	-0.8	-0.5	-0.6	-0.4	0.4	-0.3	-0.7	-0.2	-1.5	-0.4	-0.2	-0.3	-0.5	-1.6	-0.6	-0.9	-1.6	1.0	-0.2	-1.4
Medication: Omeprazole	0.5	0.6	2.0	-0.8	-0.6	-0.5	-1.1	-1.3	-0.6	-0.8	-0.7	0.7	-0.8	-0.1	-0.8	0.0	-1.1	-0.6	-0.3	0.8	-1.4	-1.0	0.7	-0.7	-0.3	-0.0	1.0
Mean time to correctly identify matches	0.5	0.9	3.4	1.0	1.1	0.9	0.6	0.6	0.4	1.0	0.7	1.9	1.0	0.4	0.9	0.7	0.9	0.9	1.0	1.6	0.6	1.0	1.0	0.2	0.9	0.5	1.1
Illnesses of siblings: Diabetes	0.5	0.7	2.0	-0.6	-0.9	-1.3	-0.2	0.0	-0.6	-0.2	-1.0	1.0	-0.7	-1.1	-0.9	-1.3	-0.5	-1.0	-1.1	-0.1	-0.1	-0.5	-0.8	-0.6	-1.4	-0.9	-0.1
Smoking status: Previous	0.5	0.7	1.8	-1.3	-0.6	-0.2	-1.0	-0.3	-0.9	-1.2	-1.4	0.5	-1.2	-0.9	-0.7	-0.8	-1.1	-1.2	-1.1	-0.6	0.0	-1.0	-0.2	0.3	-0.5	-0.8	-0.1
Ever had bowel cancer screening	0.5	0.6	3.1	-0.6	-0.5	-1.1	-0.6	-0.0	-1.3	-0.4	-1.0	0.8	-0.6	-1.2	0.1	-1.8	-0.3	-0.4	-0.6	-0.7	-1.2	-0.6	0.4	-1.0	-0.2	-0.5	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	4.3	-0.9	0.3	-0.7	0.0	-0.3	0.6	-0.4	-0.7	-0.1	-0.9	0.2	-0.8	-0.5	-0.6	-1.1	-0.8	-0.5	-0.0	-0.5	0.1	0.7	-1.7	-0.6	2.1
Smoking status: Current	0.5	0.8	1.7	-1.3	-1.1	-0.9	-0.5	-0.3	-0.0	-0.8	-0.8	-1.1	-1.3	-0.4	-0.5	-0.3	-1.0	-0.9	-1.3	-0.7	-0.7	-1.2	-1.0	-0.5	-1.1	-0.5	-1.1
Average weekly champagne plus white wine intake	0.5	0.7	2.2	-1.3	-0.2	0.0	-1.4	-1.0	-1.0	-0.9	-0.6	1.0	-1.0	-0.6	-0.5	-0.2	-1.1	-0.6	-0.6	0.0	-1.5	-1.3	-0.2	-0.5	1.3	-0.7	-0.1
Supplements: Fish oil (including cod liver oil)	0.5	0.6	3.8	1.1	0.4	1.9	0.3	-0.6	-0.6	1.1	0.8	-0.8	1.2	0.2	0.7	0.8	0.4	0.9	0.7	0.7	0.7	0.7	0.1	0.2	1.1	0.3	-0.3
Unable to work because of sickness or disability	0.5	0.7	2.5	0.6	0.6	0.0	0.3	0.4	1.6	0.6	0.1	-1.4	0.4	1.4	1.1	-0.0	0.4	0.2	0.7	0.7	0.8	0.7	1.5	0.8	0.5	1.2	0.5
Cardiovascular Disease	0.4	1.4	4.6	-1.7	-0.7	-2.1	-0.9	1.4	0.1	-1.8	-2.1	-0.7	-1.8	-0.6	-1.2	-1.1	-0.7	-1.9	-0.9	-0.4	0.2	-0.8	0.0	0.1	-1.3	-0.9	-0.2
Relative age of first facial hair	0.4	0.8	4.2	0.8	0.6	0.6	1.2	0.9	1.3	1.1	0.3	-1.7	0.5	0.5	0.7	0.4	0.7	0.7	0.4	0.9	2.1	1.2	0.6	0.6	0.4	0.4	0.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.1	0.8	0.3	0.2	0.4	-0.0	0.7	0.8	0.9	1.1	0.7	1.0	0.8	0.2	0.6	0.6	0.7	0.4	-0.6	0.5	0.3	0.6	0.4	0.8	0.1
Relative age voice broke	0.4	0.6	1.3	1.1	0.3	1.1	1.0	0.1	0.3	0.7	1.0	-1.0	1.0	0.9	0.9	0.3	0.7	0.9	0.8	0.3	1.1	1.0	0.5	0.6	0.5	1.0	-0.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.7	0.1	-1.1	-1.1	-1.3	-0.8	-0.7	-0.2	-0.6	-0.5	-0.0	-0.2	-1.1	-0.0	-0.4	-0.7	-0.3	0.3	-0.4	-0.4	-0.3	-0.4	-1.1	-0.8	0.3
Medication: Levothyroxine sodium	0.4	0.7	1.9	-0.9	-1.0	-1.4	-1.0	-0.5	-1.0	-0.6	-0.8	1.2	-0.7	-0.2	-1.3	0.2	-0.7	-0.6	-0.2	0.2	-1.2	-0.8	-0.2	-0.8	0.4	-0.7	1.3
Allergy	0.4	0.9	3.2	1.1	0.8	0.9	0.5	0.2	1.4	0.5	0.8	0.8	1.1	0.7	0.7	1.3	0.7	1.0	1.0	1.6	1.0	1.0	0.4	0.7	1.8	0.8	-0.0
Pain all over the body in last month	0.4	0.4	2.9	-0.5	-0.5	-0.6	-0.5	-0.2	0.5	0.0	-0.4	-0.3	-0.5	-0.4	-0.7	-0.9	-0.4	-0.9	-0.7	0.4	-0.5	-0.6	-0.3	0.0	-1.7	-0.5	-0.5
Medication: Ramipril	0.4	0.5	1.8	0.6	0.3	-0.6	0.7	0.6	0.7	-0.0	0.4	0.6	0.5	1.2	0.3	0.9	0.7	0.3	0.6	0.8	0.5	0.8	0.0	1.4	-0.3	0.6	1.0
Neuroticism score	0.4	0.7	2.9	-0.2	1.0	0.4	0.6	1.2	1.7	-0.3	-0.2	-1.2	-0.1	0.8	0.1	0.8	0.4	0.4	0.5	0.5	1.3	0.5	1.6	1.6	0.2	0.6	1.0
Asthma	0.4	0.8	3.3	-0.7	-0.2	-1.2	0.3	-0.4	-1.6	-0.5	-0.3	-0.5	-0.6	-0.6	0.3	-1.8	-0.3	-0.3	-0.7	-1.7	-1.8	-0.5	-0.9	-0.9	-0.9	0.0	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.6	0.2	0.9	0.6	0.6	0.2	0.9	0.4	0.6	-0.3	0.2	0.9	1.6	-0.0	0.3	0.5	0.3	0.9	0.2	0.2	1.1	0.7	1.0	1.1	0.7
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.6	0.5	0.9	0.4	0.6	0.4	0.4	0.6	0.6	0.6	0.6	0.4	1.0	-0.1	0.7	0.8	0.7	0.0	-0.0	0.5	1.1	0.3	0.4	0.9	1.6
Body fat percentage	0.4	1.4	7.1	-1.9	-0.6	-1.7	-1.3	0.2	-0.4	-1.6	-1.3	-2.7	-1.7	0.5	-0.5	-0.9	-1.0	-1.6	-0.7	-1.0	-1.1	-1.1	-0.7	0.5	-1.3	0.1	-0.6
Exposure to tobacco smoke outside home	0.4	0.6	1.9	-1.2	-0.7	-1.1	-1.0	-0.2	-0.5	-0.7	-1.4	-0.0	-1.1	-0.7	-0.9	-0.3	-0.9	-0.9	-0.7	0.6	0.0	-0.8	-0.4	-0.1	-0.5	-0.5	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.4	-1.2	0.1	-0.4	-0.7	0.5	0.8	-0.6	-0.9	-1.2	-1.1	0.4	-1.1	0.8	-0.6	-0.8	-0.4	0.0	0.6	-0.5	-0.2	0.9	-1.2	-0.1	0.6
Number of children fathered	0.4	0.5	2.6	-0.8	-0.4	0.4	-0.2	-1.5	-0.2	-0.8	0.1	-0.0	-0.7	0.0	0.1	-0.3	-1.1	-0.6	-0.9	-1.6	-1.1	-1.0	-0.3	0.4	-0.6	0.1	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.3	-0.8	-0.4	-0.3	-1.1	-0.6	-0.6	-0.4	-0.6	1.1	-0.7	-0.3	-1.0	-0.0	-0.8	-0.3	-0.4	-0.2	-0.4	-0.7	-1.1	-0.7	-0.7	-0.6	-0.8
Leg fat mass (right)	0.4	1.4	4.5	-2.1	-0.3	-1.9	-1.2	0.0	0.2	-1.4	-1.4	-1.6	-1.9	0.4	-0.6	-0.7	-1.2	-1.6	-0.8	-1.1	-1.4	-1.3	-0.3	0.6	-1.4	0.1	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.6	-0.6	0.7	-0.3	0.8	1.6	0.9	-0.3	-0.2	-0.8	-0.3	0.4	0.5	0.5	0.5	0.1	0.3	0.6	0.9	0.4	0.4	0.9	0.9	0.3	1.3
Asthma (self-reported)	0.4	0.8	2.8	-0.8	-0.2	-1.4	0.4	-0.3	-1.4	-0.6	-0.4	-0.9	-0.7	-0.6	0.3	-1.7	-0.4	-0.5	-0.8	-1.6	-1.6	-0.5	-0.9	-0.8	-0.9	-0.0	0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	5.4	0.5	0.5	0.0	-0.2	-0.4	-0.7	0.7	0.1	2.3	0.6	-0.3	-0.9	-1.2	0.3	0.5	0.6	0.5	-0.8	0.2	-0.2	-0.6	0.2	-0.4	0.6
Miserableness	0.4	0.7	3.3	-0.1	1.4	0.7	0.8	0.4	1.8	-0.0	0.3	-0.2	0.2	0.8	0.8	0.4	0.3	0.9	0.4	0.6	0.9	0.5	1.7	1.7	-0.2	1.0	0.6
Hearing aid user	0.4	0.5	1.6	0.8	-0.1	-0.3	0.5	0.2	1.0	0.1	0.5	-1.1	0.6	1.0	1.3	1.0	0.6	0.0	0.4	-0.1	0.3	0.5	1.2	0.4	0.5	1.0	0.3
Medication: Blood pressure	0.4	0.7	3.8	-0.3	-0.7	-1.0	-0.9	-0.9	-1.3	-0.7	-0.7	0.1	-0.3	-0.6	-0.6	-1.8	-0.5	-0.7	-0.1	-0.5	-2.0	-0.5	-0.3	-0.6	0.1	-0.7	-0.6
Irritability	0.4	0.6	2.4	-0.8	1.2	0.9	0.3	0.1	1.4	-0.2	-0.3	0.5	-0.5	0.6	-0.0	0.5	-0.3	0.3	0.2	1.0	0.6	0.1	1.3	1.5	1.0	0.3	1.3
Age started oral contraceptive pill	0.4	0.5	2.6	-0.1	-0.7	-0.0	-0.9	-0.4	-0.2	-0.4	-0.5	0.2	-0.3	-0.6	-1.4	-0.9	-0.4	-1.0	-0.3	-1.3	-0.6	-0.7	-0.4	-0.2	-1.6	-1.1	-0.1
Alcohol drinker status: Previous	0.4	0.4	1.3	-0.6	-0.8	-1.1	-0.8	-0.5	-0.5	-0.9	-0.9	0.2	-0.6	-0.5	-0.2	-0.7	-0.6	-1.0	-0.5	1.0	-0.3	-0.4	-0.9	-0.2	-0.4	-0.6	-0.3
Crohns Disease (2017)	0.3	0.6	1.3	0.8	1.2	0.8	1.1	0.9	0.6	0.8	0.9	-0.5	0.9	0.5	0.5	0.4	1.1	0.9	1.1	-0.4	0.5	0.9	0.3	0.4	0.7	0.8	0.3
Verbal and Numeric Reasoning (VNR)	0.3	0.6	2.2	-1.3	0.1	-0.7	-0.2	0.7	-0.9	-1.1	-0.8	-1.4	-1.0	-0.9	0.3	-0.9	-0.3	-0.3	-0.6	-0.5	-0.5	-0.5	-0.4	-1.0	1.5	-0.4	-0.8
Blood Platelet Count	0.3	3.9	13.5	-3.7	-1.2	-2.2	-2.2	-0.0	-0.2	-2.9	-3.3	-0.3	-3.4	-1.8	-1.3	-1.3	-2.5	-2.6	-2.3	-0.7	-0.5	-2.6	-0.9	-0.1	-1.4	-1.6	-0.2
Smoking Status	0.3	0.7	2.5	-1.6	-0.9	-0.5	-0.4	0.7	-0.0	-1.0	-1.3	-0.5	-1.5	-0.3	-0.1	-0.1	-0.9	-1.0	-1.4	-0.2	0.7	-1.0	-0.2	0.7	-1.1	-0.2	-0.5
Respiratory disease	0.3	0.7	3.0	-0.6	0.0	-0.7	0.3	-0.5	-1.6	-0.5	-0.1	-0.5	-0.6	-0.3	-0.1	-1.7	-0.4	-0.4	-0.6	-1.6	-1.6	-0.5	-0.5	-0.4	-1.4	-0.0	0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.5	-1.2	-0.2	-0.8	-0.5	0.7	0.3	-1.6	-0.8	-0.5	-1.1	-0.2	-0.5	-0.7	-0.5	-0.7	-0.4	-1.0	-0.1	-0.6	-0.1	0.5	-1.5	-0.2	-0.6
Number of treatments/medications taken	0.3	0.5	1.9	-0.2	0.7	0.4	0.2	0.2	0.7	0.5	0.0	-0.8	-0.1	1.1	0.4	0.6	-0.1	0.1	0.6	0.6	0.6	0.3	1.2	1.2	0.1	1.0	1.4
Hearing difficulty/problems: Yes	0.3	0.4	1.7	1.1	-0.1	-0.1	0.1	0.0	-0.7	0.8	0.4	-0.2	0.9	0.0	0.5	-0.9	0.7	0.1	0.4	1.3	-0.4	0.4	0.7	-0.5	1.3	-0.1	0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.6	-0.5	-0.2	-0.9	-0.2	0.8	0.9	-0.7	-0.8	-1.3	-0.7	0.2	0.8	0.1	-0.1	-0.8	-0.2	0.5	0.5	0.0	0.2	0.6	-0.8	0.1	-1.2
Medication: Metformin	0.3	0.5	1.9	0.3	0.5	0.5	0.7	1.3	0.9	-0.1	0.5	-1.4	0.2	0.5	1.0	0.3	0.7	0.5	0.6	-0.3	0.7	0.6	0.8	1.2	-0.3	0.5	-0.2
Diabetes (father)	0.3	0.4	3.0	0.3	-0.9	-0.0	-0.1	-1.2	-0.6	0.2	0.2	1.7	0.0	-0.1	0.4	0.7	-0.5	-0.1	-0.7	-0.1	-0.6	-0.5	0.4	0.1	-0.7	-0.3	0.2
Fed-up feelings	0.3	0.6	2.4	-1.2	0.9	-0.0	0.0	0.0	1.6	-1.5	-0.9	-1.3	-1.1	0.2	-0.1	-0.2	-0.7	-0.2	-0.2	-0.4	-0.1	-0.4	0.5	1.0	-0.3	-0.1	0.7
Stomach or abdominal pain in last month	0.3	0.4	3.6	0.2	0.3	0.8	0.9	0.4	0.5	0.5	0.3	-1.9	0.2	0.5	0.5	0.1	0.3	0.4	0.2	-0.8	0.8	0.4	0.6	0.7	-0.1	0.5	0.2
Medication: Atenolol	0.3	0.4	1.5	-0.8	0.2	-0.3	0.2	1.0	0.9	-1.0	-0.8	-0.2	-0.7	-0.1	-0.1	-0.3	-0.1	-0.5	-0.0	0.6	0.8	0.1	-0.5	0.9	-0.9	0.1	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	4.1	-0.3	0.8	-0.0	0.5	0.5	2.0	-0.2	-0.5	-0.4	-0.4	0.5	0.2	-0.0	-0.1	0.3	0.1	0.1	1.1	0.2	0.7	1.1	0.3	0.3	0.8
Hearing difficulty/problems with background noise	0.3	0.5	2.0	0.1	-0.6	-0.8	-0.3	-0.6	-0.9	0.7	-0.4	-1.2	0.1	-0.6	-1.0	-1.4	-0.1	-0.6	-0.3	0.9	-0.5	-0.1	-0.1	-0.7	-0.0	-0.6	1.4
Mouth/teeth dental problems	0.3	0.5	2.4	0.6	0.5	-0.4	0.3	-0.1	1.1	1.0	0.9	1.0	0.7	0.7	0.2	0.2	0.5	0.3	0.4	0.6	-0.1	0.4	0.5	-0.4	-0.5	0.6	1.6
Heart attack	0.3	0.4	1.8	-0.2	0.7	0.1	0.4	0.1	1.2	-0.2	0.1	-1.4	-0.2	0.8	-0.2	0.4	0.0	0.1	0.2	0.0	0.2	0.2	0.7	1.3	0.1	0.2	1.3
Fluid intelligence score	0.3	0.7	3.8	-0.6	-0.4	-0.3	-0.1	0.2	-1.6	-1.0	-0.1	-1.0	-0.3	-1.3	-0.1	-0.4	-0.1	0.0	-0.4	-0.7	-0.5	-0.2	-0.9	-1.5	0.9	-0.7	-2.0
Arm fat percentage (right)	0.3	1.1	4.6	-0.5	1.1	-0.0	0.6	1.6	1.1	-0.2	0.3	-2.1	-0.1	2.0	1.2	0.8	0.7	0.1	1.1	0.2	0.1	0.5	0.7	1.8	0.5	1.8	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.2	0.2	0.0	-0.7	0.1	-0.8	-0.4	0.3	0.1	-0.2	0.2	-0.6	0.3	-1.2	-0.0	0.2	-0.1	-1.5	-1.1	-0.1	-0.3	-0.7	-0.7	-0.3	0.8
Illnesses of mother	0.3	0.4	2.2	-0.4	-0.5	-1.1	-0.7	-0.2	-0.4	-0.2	-0.7	-0.4	-0.5	-0.1	-1.1	-1.5	-0.4	-0.5	-0.1	0.9	-0.6	-0.3	-0.6	-0.6	0.1	-0.4	0.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	2.8	0.5	-0.6	0.3	0.1	-0.3	-0.6	1.1	0.3	1.1	0.4	-0.4	0.1	-0.4	0.2	0.2	-0.1	1.0	-0.5	-0.0	-1.0	-1.4	0.7	-0.0	-1.7
Glaucoma (self-reported)	0.3	0.3	1.1	0.1	0.5	-0.2	0.8	0.4	0.7	-0.4	0.1	1.0	0.0	0.7	0.9	0.9	0.3	-0.1	0.1	0.4	0.4	0.4	0.7	0.6	0.4	0.5	0.8
Leg fat percentage (right)	0.3	0.9	5.6	-1.5	0.7	-1.0	-0.5	1.3	0.7	-0.8	-0.8	-2.4	-1.2	1.4	0.3	0.1	-0.2	-0.8	0.3	-0.1	-0.1	-0.3	0.7	1.6	-0.4	1.1	0.8
Health satisfaction	0.3	0.4	1.6	-1.1	-0.1	-0.3	-0.4	-0.1	0.5	-1.3	-0.6	-0.1	-1.0	-0.1	-0.0	0.2	-0.7	-0.6	-0.4	-1.2	-0.7	-0.8	0.1	0.4	-0.4	-0.2	-0.1
Neck or shoulder pain in last month	0.3	0.5	3.2	0.1	0.4	0.4	0.7	0.3	1.8	-0.5	0.1	-0.8	-0.0	0.4	1.0	1.1	0.0	0.3	0.1	-0.1	0.7	0.2	1.0	1.1	0.6	0.5	-0.1
Medication: Allopurinol	0.3	0.4	1.4	-0.5	-0.8	-0.4	-0.2	-0.9	-0.3	0.2	-0.4	-0.4	-0.5	-0.6	-0.3	-0.6	-0.7	-0.4	-0.4	-0.3	-1.0	-0.5	-0.9	-1.2	0.4	-0.5	-0.7
Overall health rating	0.3	0.6	3.2	-0.2	0.7	-0.1	0.6	0.4	1.0	-0.1	-0.0	-1.8	-0.2	1.3	1.2	0.5	0.2	0.1	0.4	-0.2	0.1	0.4	1.3	1.4	0.7	1.0	0.8
Family relationship satisfaction	0.3	0.4	2.5	0.6	0.4	0.4	1.3	0.4	0.9	0.5	0.4	1.6	0.5	0.0	0.6	0.2	0.5	0.8	0.2	-0.2	0.9	0.6	-0.1	-0.4	0.2	0.3	0.8
Illnesses of father: Heart disease	0.3	0.4	1.8	0.7	0.1	0.7	0.7	0.2	0.0	0.9	0.9	-1.4	0.7	1.0	0.6	0.1	0.5	0.3	0.4	0.1	0.7	0.6	0.6	1.0	0.0	1.0	-0.0
Arm fat percentage (left)	0.3	1.1	4.5	-0.5	1.1	-0.1	0.5	1.6	1.1	-0.2	0.4	-2.1	-0.1	2.1	1.1	0.8	0.7	0.1	1.2	0.1	0.0	0.5	0.8	1.8	0.4	1.9	-0.1
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.0	-0.9	-0.2	0.5	-0.2	-0.8	-0.2	-0.8	-0.6	-0.6	-0.9	0.0	-0.4	0.4	-1.0	-0.4	-0.7	0.0	-0.1	-0.9	-0.0	0.8	-0.3	-0.4	-0.9
Friendships satisfaction	0.3	0.4	2.0	-1.4	-0.4	-0.2	-0.7	-0.1	0.1	-0.8	-0.7	-0.1	-1.2	0.6	0.2	-0.0	-1.0	-0.8	-0.6	-0.8	0.1	-0.9	0.5	0.6	-0.2	0.5	0.7
Commuting to job workplace: Walk	0.3	0.3	2.5	-0.1	0.5	0.1	0.6	1.6	0.9	-0.3	-0.1	-0.1	-0.1	-0.3	-0.1	-0.1	0.5	0.1	0.1	0.2	1.2	0.4	-0.3	0.4	-0.3	-0.2	0.5
Breast cancer (self-reported)	0.3	0.3	2.4	-0.1	-0.1	0.1	-0.2	0.2	-0.3	0.3	-0.1	-0.1	-0.0	-0.8	-1.1	0.3	-0.0	-0.0	0.0	-0.1	0.1	-0.1	-0.6	-1.6	0.5	-1.0	-1.0
Osteoarthritis (self-reported)	0.3	0.4	1.4	0.9	-0.2	-0.0	-0.1	-0.7	-0.4	1.2	0.1	0.2	0.8	-1.0	0.6	-0.9	0.3	0.1	0.1	-0.2	-0.4	0.2	0.6	-1.1	0.8	-0.3	0.4
Medication: Gliclazide	0.3	0.4	1.8	0.2	0.5	-0.0	0.8	1.0	-0.6	-0.2	0.6	0.7	0.3	0.7	1.4	1.0	0.7	0.7	0.5	0.0	-0.1	0.5	0.4	0.2	0.6	0.7	-0.1
Number of self-reported non-cancer illnesses	0.3	0.6	3.7	-1.2	-0.2	-0.8	-0.3	0.8	-0.6	-1.3	-1.2	-1.9	-1.1	-0.3	-0.5	-0.3	-0.4	-0.9	-0.4	-0.7	-0.1	-0.4	-0.1	-0.1	-0.7	-0.2	-0.4
Mother’s age at death	0.3	0.4	1.9	1.0	0.1	0.4	0.3	-0.0	-0.9	0.6	0.8	1.4	0.9	0.3	-1.0	-0.0	0.6	0.7	0.5	0.4	-0.1	0.5	-0.3	-0.5	-0.8	-0.2	1.0
Commuting to job workplace: Public transport	0.3	0.4	3.2	-0.8	0.0	-0.4	0.2	1.0	-0.0	-0.8	-0.4	-1.1	-0.7	-0.3	-0.3	0.2	0.0	-0.5	-0.3	-0.2	-0.2	-0.2	-0.7	-0.1	0.5	-0.3	-1.8
Leg fat percentage (left)	0.3	1.0	6.9	-1.1	0.9	-0.4	-0.1	1.3	0.7	-0.4	-0.3	-2.6	-0.7	1.6	0.8	0.5	0.1	-0.3	0.5	-0.1	0.1	0.1	0.8	1.9	-0.2	1.4	0.9
Leg fat mass (left)	0.3	1.2	3.8	-1.9	-0.3	-1.6	-1.0	-0.1	0.1	-1.2	-1.2	-1.8	-1.7	0.4	-0.5	-0.7	-1.1	-1.5	-0.8	-1.1	-1.4	-1.2	-0.4	0.6	-1.4	0.1	-0.5
Neuroticism (Nagel 2018)	0.2	0.5	3.3	0.3	1.0	0.0	0.7	0.2	0.5	0.6	0.4	-0.8	0.3	1.1	0.1	-0.1	0.4	0.5	0.4	0.2	-0.1	0.5	1.5	0.6	-0.3	0.8	1.8
Schizophrenia vs Biploar Disorder	0.2	0.3	1.1	0.3	-0.2	-0.8	-0.4	-1.0	0.2	0.1	-0.3	1.0	0.1	-0.3	-0.8	-0.2	-0.3	-0.5	-0.4	0.4	-0.4	-0.2	-0.6	-0.3	-0.7	-0.7	1.1
Irritable Bowel Disease (IBD)	0.2	0.4	1.9	-0.3	-0.5	-0.7	-0.5	-0.2	0.3	-0.2	-0.6	-0.7	-0.4	-1.0	-0.9	-0.5	-0.4	-0.7	-0.5	-1.4	-0.2	-0.6	-0.6	-1.0	-0.7	-0.8	0.1
Prostate Cancer	0.2	0.3	2.0	-0.1	-0.2	0.3	0.1	-0.5	-0.9	0.2	-0.2	-0.9	-0.1	-0.6	0.3	-1.4	-0.3	-0.2	-0.5	-0.7	-0.0	-0.2	-1.1	-1.1	0.3	-0.6	-0.1
Crohns Disease (2012)	0.2	0.4	3.8	0.0	-0.0	0.8	-0.1	-0.3	-0.9	0.1	0.3	-1.1	0.2	-0.3	-0.3	0.1	-0.0	0.1	0.3	-0.9	-0.3	-0.0	-0.8	-1.0	0.3	-0.1	-1.9
Mean Putamen Volume	0.2	0.3	0.8	-0.2	-0.5	-0.9	-0.5	-0.4	-0.6	-0.8	-0.6	0.8	-0.3	-0.3	0.5	-0.1	-0.3	-0.5	-0.5	0.3	-0.7	-0.5	0.7	-0.5	0.5	-0.2	0.6
HDL Cholesterol	0.2	0.3	2.6	0.3	-0.3	0.0	-0.3	-0.9	-0.5	0.3	0.1	1.6	0.2	-0.2	-0.2	0.8	-0.3	0.2	-0.1	-0.9	-0.1	-0.2	-0.5	-0.6	0.0	-0.3	-0.2
Lupus	0.2	0.4	1.5	0.1	-0.0	0.2	0.4	0.9	1.2	0.5	0.1	-0.9	0.0	0.9	-0.0	0.3	0.4	-0.2	0.3	0.0	1.1	0.4	0.4	1.1	-0.6	0.5	0.3
Blood Eosinophil Count	0.2	1.4	4.2	-1.9	-0.7	-1.7	-0.5	0.7	0.2	-1.8	-1.3	-0.9	-1.9	-0.1	-0.0	0.1	-1.0	-1.4	-1.4	0.0	0.0	-1.0	-1.3	0.2	-2.0	-0.1	-2.0
Chronotype (morning person)	0.2	0.4	2.4	0.8	-0.1	0.4	0.2	-0.3	-0.1	1.6	0.5	0.7	0.8	-0.7	-1.0	0.3	0.3	0.3	0.1	0.2	0.4	0.3	-0.9	-0.4	-0.6	-1.0	0.8
Systolic blood pressure, automated reading	0.2	0.7	1.9	0.8	1.2	0.3	1.4	1.2	0.5	0.8	0.7	0.8	0.8	0.4	0.7	0.7	1.1	0.8	0.9	0.4	0.8	1.1	1.0	0.1	0.5	0.5	0.4
High blood pressure	0.2	0.5	3.5	-0.5	0.7	-0.5	0.4	1.9	1.0	-0.5	-0.9	-0.6	-0.5	0.5	0.4	-0.2	0.4	-0.4	0.6	0.6	0.7	0.5	1.1	1.0	0.2	0.4	-0.4
Nervous feelings	0.2	0.4	1.5	-0.5	-0.1	-1.1	0.1	1.2	0.3	-0.6	-1.0	-1.1	-0.5	-0.6	-1.2	-1.1	0.2	-0.3	-0.0	0.4	0.5	0.3	-0.2	-0.0	-0.4	-0.7	-0.3
Medication: Simvastatin	0.2	0.3	0.8	-0.5	-0.4	-0.0	-0.1	-0.2	-0.8	-0.7	-0.5	-0.8	-0.5	-0.4	-0.6	-0.9	-0.5	-0.7	-0.5	-0.5	-0.2	-0.4	-0.0	0.2	-0.9	-0.5	0.0
Time employed in main current job	0.2	0.3	0.9	0.5	0.6	0.5	0.6	0.2	0.6	0.4	0.5	0.7	0.6	0.6	0.3	0.2	0.5	0.7	0.6	0.9	-0.0	0.5	-0.2	0.7	0.4	0.6	-0.2
Happiness	0.2	0.3	1.4	0.4	0.6	0.3	0.6	-0.1	0.8	-0.1	0.7	-0.3	0.4	0.1	1.2	-0.3	0.4	0.7	0.4	-0.6	-0.5	0.3	0.1	-0.5	0.1	0.6	-0.5
Mouth/teeth dental problems: Dentures	0.2	0.4	1.7	-0.8	-0.1	-0.1	-0.5	-0.1	0.1	-1.1	-1.2	-0.4	-0.9	0.0	-0.3	-0.3	-0.7	-0.8	-0.5	0.5	0.4	-0.4	-0.1	1.3	-0.2	-0.3	-0.5
Lung cancer (father)	0.2	0.2	2.0	0.0	0.6	-0.3	0.2	0.6	0.3	0.1	-0.3	0.5	-0.0	0.2	0.2	-0.4	0.3	0.2	0.2	1.4	0.0	0.2	0.4	0.5	0.5	0.0	-0.2
Arm fat mass (right)	0.2	0.9	3.2	-1.6	-0.1	-1.4	-0.7	0.3	0.6	-1.1	-0.9	-1.8	-1.4	0.6	0.1	-0.3	-0.7	-1.2	-0.5	-0.8	-1.1	-0.9	-0.2	0.6	-0.8	0.4	-1.1
Hair/balding pattern: Pattern 4	0.2	0.4	2.6	0.3	0.3	0.8	0.3	-1.4	1.0	0.5	0.5	1.6	0.5	-0.0	0.2	0.9	-0.4	0.2	-0.0	0.1	0.4	0.0	-0.1	0.7	-0.6	-0.1	0.0
Birth weight of first child	0.2	0.4	2.3	0.0	0.2	0.6	0.2	0.4	1.5	0.2	0.1	-1.1	-0.1	0.5	0.4	0.9	0.0	-0.4	-0.3	-0.5	0.9	-0.0	-0.4	1.0	-1.2	0.1	-0.5
Pulse wave reflection index	0.2	0.2	1.7	0.4	0.3	0.8	-0.1	-0.6	-0.2	0.6	0.4	1.3	0.5	0.2	-0.5	0.3	0.0	0.5	0.4	0.3	0.2	0.2	0.0	-0.1	-0.1	0.1	1.0
Headache pain in last month	0.2	0.3	1.4	0.3	1.2	0.7	0.4	0.1	0.5	0.2	0.4	0.4	0.3	0.9	0.8	0.2	0.3	0.6	0.6	-0.4	-0.1	0.3	0.4	-0.0	0.4	1.2	0.1
Gout (self-reported)	0.2	0.3	2.5	-0.3	-0.1	-0.1	-0.0	-0.7	-0.6	0.3	0.1	0.7	-0.2	-0.6	0.1	-0.3	-0.4	0.0	-0.0	-0.2	-1.3	-0.4	-0.0	-1.6	0.8	-0.2	-0.8
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	2.4	-0.9	-0.2	-0.5	-0.6	0.1	-0.1	-0.8	-0.6	1.6	-0.7	0.4	-0.7	0.9	-0.5	-0.4	0.0	-0.5	-0.5	-0.5	0.5	0.3	0.4	-0.2	1.1
High blood pressure (siblings)	0.2	0.2	1.5	0.1	0.4	0.9	0.0	0.2	0.2	-0.1	-0.2	-1.2	-0.1	0.4	-0.1	0.4	-0.0	-0.2	0.1	-0.1	0.6	0.2	0.4	1.1	-0.4	0.1	-0.7
Pulse wave peak to peak time	0.2	0.2	1.1	0.2	-0.2	-0.7	-0.0	0.1	0.1	0.3	-0.1	0.8	0.2	-0.6	-0.4	-0.8	0.2	-0.1	-0.1	0.4	-0.3	0.2	-1.0	-0.6	-0.2	-0.4	-0.7
Shortness of breath walking on level ground	0.2	0.2	1.4	-0.5	-0.2	-1.2	-0.3	0.5	0.5	-0.3	-0.7	0.2	-0.6	0.4	0.3	0.0	-0.1	-0.6	-0.1	-0.0	-0.2	-0.2	0.3	0.3	0.1	0.1	1.0
Medication: Ibuprofen	0.2	0.2	1.1	-0.0	0.5	0.3	0.3	0.1	0.5	0.5	0.6	-0.5	0.1	0.6	1.1	-0.1	0.1	0.3	0.1	0.6	-0.0	0.0	0.8	0.2	0.7	1.0	0.6
Number of full sisters	0.2	0.2	1.1	-0.4	0.2	-0.4	0.6	-0.3	0.9	-0.2	-0.1	-1.0	-0.3	0.1	0.6	-0.9	-0.2	-0.1	-0.4	0.5	0.2	0.1	-0.3	0.4	-0.7	0.3	-0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	2.0	-0.5	0.1	0.1	-0.5	-0.1	-0.9	0.1	-0.3	1.4	-0.1	-0.1	-0.8	-0.0	-0.2	-0.4	0.2	0.6	-0.3	-0.1	-0.3	0.1	0.7	-0.2	0.5
Long-standing illness, disability or infirmity	0.2	0.3	1.0	-0.6	-0.6	-1.0	-0.5	-0.2	0.6	0.0	-0.6	-0.9	-0.7	0.1	-0.2	0.2	-0.5	-0.8	-0.3	-0.1	-0.3	-0.5	0.1	-0.2	-0.6	-0.2	-0.5
Diabetes diagnosed by doctor	0.2	0.3	1.3	-0.9	0.1	-0.4	-0.1	0.4	0.1	-1.1	-0.6	-0.8	-0.8	0.1	0.1	-0.0	-0.4	-0.5	-0.2	-0.6	-0.3	-0.3	0.1	0.6	-0.5	-0.0	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	2.3	0.1	-1.0	0.0	-0.3	-0.1	-1.2	-0.1	-0.4	0.1	0.1	-1.1	-0.3	-0.5	-0.0	-0.0	-0.1	-0.2	-0.0	-0.1	-1.1	-0.6	-0.3	-1.0	-1.5
Back pain experienced in last month	0.2	0.3	1.6	-0.1	0.2	0.5	0.1	0.1	0.4	-0.1	-0.6	-1.2	-0.2	0.1	0.1	0.1	-0.2	-0.1	-0.1	0.5	0.9	0.1	1.1	1.2	0.6	-0.0	1.3
Arm fat mass (left)	0.2	0.7	3.1	-1.5	-0.0	-1.4	-0.6	0.4	0.6	-1.0	-0.8	-1.8	-1.3	0.8	0.1	-0.4	-0.6	-1.1	-0.3	-0.8	-1.0	-0.8	-0.1	0.7	-0.7	0.6	-0.8
Medication: Lisinopril	0.2	0.3	1.1	-0.4	0.1	-0.7	-0.3	0.2	-0.8	0.1	-0.2	-1.1	-0.2	-0.6	-0.4	-0.3	-0.0	-0.4	-0.1	-0.3	-0.8	-0.2	-0.7	-0.9	0.2	-0.4	-0.7
Number of operations (self-reported)	0.2	0.3	1.1	0.5	0.2	0.2	0.5	0.5	0.6	0.6	0.6	-0.5	0.5	1.1	0.7	0.6	0.5	0.2	0.5	0.6	0.7	0.6	0.4	0.6	0.3	0.6	0.7
Average weekly beer plus cider intake	0.2	0.3	1.3	0.8	0.0	-0.3	0.4	-0.5	-0.7	0.7	0.5	-0.1	0.8	-0.4	0.4	-0.9	0.5	0.6	0.4	0.2	-1.1	0.5	0.4	-0.9	0.9	0.1	0.4
Diastolic blood pressure, automated reading	0.2	0.7	2.7	-0.5	-0.3	-0.9	-0.3	-1.6	-0.4	-0.5	-0.6	0.8	-0.5	-1.1	-0.9	-0.7	-0.9	-0.5	-0.6	-0.7	-1.2	-0.7	-0.9	-1.6	-1.1	-1.0	-0.5
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.4	1.1	-0.5	1.1	-0.0	-1.5	-1.0	1.0	1.4	1.0	1.1	-0.4	0.2	0.2	0.1	0.9	-0.2	-0.3	-0.5	-0.0	-0.7	-1.1	0.1	-0.1	-0.3
Pain experienced in last month	0.2	0.3	1.2	-0.4	-0.3	-1.1	-0.4	0.3	-0.9	-0.3	-0.5	0.8	-0.4	-0.6	-0.5	-0.7	-0.1	-0.6	-0.3	-0.0	-0.6	-0.2	-0.7	-1.0	-0.5	-0.4	-0.7
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.8	-0.4	0.4	-0.0	0.3	0.0	1.1	-0.5	-0.1	-1.4	-0.4	0.5	-0.4	0.2	-0.2	-0.3	-0.1	-0.2	0.1	-0.0	0.6	1.2	-0.1	-0.1	1.1
Intelligence (Savage-Jansen 2018)	0.1	0.4	4.2	-0.6	0.3	-0.1	0.0	0.8	-1.1	0.4	-0.2	-0.8	-0.3	-0.1	0.7	-0.2	0.2	0.2	0.1	0.7	-0.4	0.1	-0.3	-0.7	2.0	0.4	-1.1
Worry (Nagel 2018)	0.1	0.3	1.6	0.7	0.4	0.2	0.1	0.2	-0.1	0.3	0.5	-0.4	0.6	0.3	-0.8	-0.1	0.5	0.3	0.5	0.5	0.2	0.4	1.0	0.1	-0.5	-0.0	1.3
Primary Biliary Cirrhosis	0.1	0.1	0.9	-0.1	0.5	-0.0	0.1	-0.2	-0.2	0.1	0.3	0.6	-0.1	0.4	-0.9	-0.1	-0.2	0.2	0.3	0.1	-0.4	-0.0	-0.1	-0.3	-0.4	0.1	0.9
Triglycerides	0.1	0.2	1.3	-0.3	-0.4	-0.6	0.4	0.4	0.5	-0.2	-0.3	-1.1	-0.4	0.4	0.1	-0.1	-0.0	-0.4	-0.3	1.0	0.1	0.1	-0.0	0.5	-0.2	0.1	-0.9
Blood White Count	0.1	1.1	7.1	-1.9	0.0	-0.8	-0.0	0.8	1.5	-0.8	-1.4	-2.7	-1.7	0.2	-0.1	0.7	-0.8	-1.1	-0.8	-0.0	0.7	-0.7	-0.8	1.1	-1.0	-0.4	0.2
Systolic Blood Pressure	0.1	0.4	1.3	0.8	0.7	0.5	1.0	0.4	0.2	1.1	0.8	0.7	0.7	0.0	-0.1	0.8	0.7	0.7	0.6	-0.1	0.4	0.7	0.7	-0.1	0.4	0.0	0.3
Allergy or Eczema	0.1	0.3	1.5	0.7	0.5	0.6	0.4	0.9	-0.2	0.8	0.6	0.9	0.6	0.0	0.3	0.2	0.8	0.6	0.6	-0.4	0.1	0.5	1.2	-0.1	0.0	0.0	0.4
Hypothyroidism (self reported)	0.1	0.3	2.6	-0.5	0.3	-0.1	-0.2	0.7	0.4	-0.4	-0.3	1.6	-0.4	0.6	-0.5	0.8	0.0	-0.0	0.5	0.7	-0.0	-0.1	0.9	0.4	0.3	0.3	1.1
Neuroticism	0.1	0.4	2.1	-0.3	0.7	0.1	0.3	0.1	0.8	-0.4	-0.2	-0.5	-0.2	0.9	-0.2	0.3	-0.1	0.1	0.0	-0.1	0.5	0.1	1.4	1.2	-0.4	0.4	1.3
Hair Pigment	0.1	3.2	56.0	0.8	1.1	0.2	1.2	0.9	0.4	0.8	1.0	7.5	1.0	0.5	1.3	-0.4	1.1	1.4	0.7	1.5	0.3	0.9	1.2	0.7	-0.3	1.1	1.2
Sensitivity / hurt feelings	0.1	0.2	1.7	-0.2	0.4	-0.3	0.6	0.8	0.4	-0.1	-0.1	-1.3	-0.1	0.2	-0.4	-0.4	0.3	-0.1	0.1	-0.6	-0.1	0.3	0.1	0.4	-0.5	0.0	0.5
Taking other prescription medications	0.1	0.2	0.9	-0.6	-0.3	-0.4	-0.2	-0.8	0.2	-0.7	-0.5	-0.6	-0.6	0.1	-0.4	-0.1	-0.7	-0.6	-0.2	-0.3	-0.6	-0.4	-0.2	0.2	-1.0	-0.3	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	1.9	-0.4	0.5	-0.2	-0.2	0.7	0.2	-0.1	-0.2	0.2	-0.3	-0.3	-0.3	-0.2	0.1	0.2	0.3	1.4	-0.0	-0.0	0.4	0.1	0.3	-0.1	-0.0
Had menopause	0.1	0.1	0.7	-0.2	-0.0	0.0	-0.6	0.6	0.3	-0.7	-0.4	-0.2	-0.3	0.3	-0.0	0.9	-0.1	-0.4	0.1	0.1	0.4	-0.2	0.3	0.4	-0.4	-0.1	-0.3
Diabetes (self-reported)	0.1	0.2	1.0	-0.5	0.0	-0.3	0.1	0.7	-0.7	-0.7	-0.3	-0.1	-0.5	-0.2	-0.1	-0.4	0.0	-0.3	-0.1	-0.4	-0.4	-0.1	-0.1	-0.0	-0.7	-0.2	-1.0
Number of live births	0.1	0.1	0.5	-0.2	0.2	-0.4	0.4	-0.1	-0.4	0.2	0.3	0.0	-0.1	0.5	0.2	0.5	-0.0	0.2	0.1	-0.7	-0.5	0.1	-0.2	0.4	0.1	0.3	0.3
Pulse rate	0.1	0.2	1.2	0.1	0.4	-0.1	0.5	0.6	1.1	-0.1	-0.3	-1.0	-0.1	0.4	0.3	-0.0	0.2	-0.0	0.4	0.8	0.8	0.3	0.2	0.8	-0.1	0.0	0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.1	0.6	-0.5	0.4	-0.1	0.1	-0.3	0.8	0.5	0.4	0.6	-0.5	0.2	-0.4	0.4	0.2	0.1	-0.0	-0.1	0.1	0.5	-0.8	0.4	0.2	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	1.8	-0.2	0.1	0.7	0.2	0.4	-0.1	-0.1	-0.0	-1.3	-0.0	0.3	0.3	0.6	0.0	0.2	0.1	0.0	0.8	0.2	0.1	0.1	1.1	0.2	-0.2
Qualifications: College or University degree	0.1	0.4	2.7	0.7	-0.4	0.7	0.0	0.8	-0.6	0.6	0.5	-0.6	0.5	-0.0	0.6	1.0	0.7	0.2	0.1	-0.1	0.6	0.3	-0.0	-0.5	1.2	0.2	-1.6
Heart disease (mother)	0.1	0.1	0.9	-0.0	-0.6	0.0	-0.3	-0.1	0.0	-0.5	0.0	-0.9	-0.1	0.0	0.0	0.8	-0.2	-0.5	-0.2	-0.3	0.3	-0.2	0.2	0.4	-0.1	-0.0	-0.3
Suffer from ‘nerves’	0.1	0.2	1.2	0.3	-0.3	0.1	-0.6	-0.6	0.0	-0.2	-0.2	0.2	0.1	-0.5	-1.1	0.2	-0.2	-0.1	-0.1	0.1	-0.2	-0.3	0.4	0.2	-0.1	-0.8	1.1
Hypertension (Self-reported)	0.1	0.4	2.1	-0.6	0.5	-0.8	0.1	1.4	1.0	-0.5	-1.0	-0.2	-0.7	0.3	0.0	-0.6	0.1	-0.6	0.2	0.3	0.4	0.2	0.8	0.7	-0.3	0.0	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.7	-0.3	0.0	0.2	-0.3	0.1	0.6	-0.2	0.1	-0.3	-0.1	0.3	-0.2	0.8	-0.1	-0.0	0.3	0.8	-0.2	-0.2	0.6	0.2	-0.1	0.2	0.7
Mood swings	0.1	0.3	1.2	-0.6	0.1	-0.6	-0.1	-0.3	0.8	-0.3	-0.6	-0.8	-0.6	0.3	0.1	0.2	-0.5	-0.5	-0.5	-0.2	-0.3	-0.4	1.1	0.8	-0.4	0.0	0.6
Myopia	0.1	0.2	1.0	0.2	0.3	1.0	0.4	-0.6	0.6	-0.1	0.6	0.4	0.2	-0.4	0.6	-0.4	-0.1	0.6	0.1	-0.5	0.3	0.0	-0.7	-0.3	0.0	0.1	0.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.6	-0.3	-0.3	0.1	-0.2	-0.0	-0.2	0.1	0.0	-0.6	-0.2	-0.0	0.3	0.2	-0.2	-0.1	-0.2	-0.0	0.1	-0.3	-0.1	-0.6	0.8	-0.1	-0.6
Tanning	0.0	0.3	1.4	-0.3	-0.5	-0.3	-0.2	-0.3	1.2	-0.6	-0.3	-1.1	-0.2	0.4	0.4	1.0	-0.4	-0.1	-0.4	-0.8	0.9	0.1	-0.4	0.4	0.5	-0.0	0.1
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.8	0.1	0.1	0.2	0.1	0.9	-0.2	0.2	0.1	-0.2	0.1	-0.0	0.0	0.0	0.4	0.0	0.3	-0.2	0.3	0.1	0.6	-0.2	-0.4	-0.1	0.2

Hub : Genes

MST1L

Models

Trait associations