Best TWAS P=2.79e-08 · Best GWAS P=6.03e-08 conditioned to 0.00406
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FAM86B1 | 0.02 | 0.02 | lasso | 3 | 0.01 | 1.3e-02 | -5.3 | -5.2 | 1.5e-07 | 0.61 | 0.01 | 0.95 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | FAM66A | 0.23 | 0.26 | enet | 29 | 0.30 | 4.7e-39 | -3.8 | -5.5 | 2.8e-08 | 0.54 | 0.38 | 0.51 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | FAM66D | 0.15 | 0.16 | bslmm | 227 | 0.17 | 5.3e-21 | 4.0 | 5.1 | 2.7e-07 | -0.47 | 0.50 | 0.40 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | FAM85A | 0.11 | 0.07 | enet | 23 | 0.11 | 4.3e-14 | -3.8 | -5.3 | 8.7e-08 | 0.57 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | BLK | 0.07 | 0.05 | blup | 115 | 0.03 | 2.4e-03 | -4.0 | 5.4 | 8.4e-08 | -0.84 | 0.06 | 0.82 | FALSE |