[Hub]/) : Traits : Peak expiratory flow (PEF) : ← →

chr9:126,927,285-128,824,378

Best TWAS P=1.86e-08 · Best GWAS P=1.99e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum PRPS1P2 0.09 0.08 enet 16 0.04 2.8e-02 -3.4 5.4 6.3e-08 0.85 0.05 0.81 FALSE
2 GTEx Nerve Tibial PRPS1P2 0.11 0.11 enet 9 0.10 1.4e-07 5.4 5.2 1.6e-07 0.93 0.02 0.98 FALSE
3 GTEx Skin Not Sun Exposed Suprapubic PPP6C 0.08 0.06 lasso 4 0.05 7.8e-04 5.4 -5.5 5.0e-08 -0.99 0.02 0.96 FALSE
4 GTEx Skin Sun Exposed Lower leg PPP6C 0.11 0.10 lasso 5 0.09 9.1e-08 5.4 -5.3 9.1e-08 -0.96 0.02 0.98 FALSE
5 GTEx Skin Sun Exposed Lower leg RABEPK 0.07 0.05 lasso 4 0.05 6.3e-05 5.5 -5.5 4.9e-08 -0.98 0.02 0.98 FALSE
6 GTEx Skin Sun Exposed Lower leg GAPVD1 0.04 0.01 lasso 4 0.01 3.8e-02 4.0 -5.4 5.7e-08 -0.87 0.07 0.90 FALSE
7 GTEx Spleen PRPS1P2 0.18 0.02 lasso 4 0.04 3.9e-02 5.5 5.4 8.0e-08 0.91 0.05 0.58 FALSE
8 GTEx Testis PPP6C 0.10 0.03 enet 13 0.01 1.1e-01 5.1 -5.5 5.0e-08 -0.82 0.04 0.78 FALSE
9 GTEx Thyroid ARPC5L 0.18 0.12 enet 17 0.16 1.5e-12 4.8 5.1 3.1e-07 0.75 0.50 0.49 FALSE
10 ROSMAP Brain Pre-frontal Cortex PPP6C 0.11 0.19 lasso 5 0.20 8.6e-26 5.5 -5.2 1.6e-07 -0.95 0.02 0.98 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma PPP6C 0.03 0.03 lasso 5 0.03 7.3e-07 5.6 -5.2 2.3e-07 -0.97 0.01 0.99 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma RABEPK 0.02 0.02 lasso 2 0.02 1.4e-04 5.6 -5.6 1.9e-08 -1.00 0.00 0.99 TRUE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PPP6C 0.05 0.06 lasso 3 0.05 1.1e-03 5.5 -5.3 1.3e-07 -0.98 0.01 0.90 FALSE
14 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PPP6C 0.17 0.06 enet 5 0.09 2.0e-04 5.4 -5.5 3.4e-08 -1.00 0.01 0.81 FALSE