[Hub]/) : Traits : Peak expiratory flow (PEF) : ← →

chr17:61,106,371-62,694,738

Best TWAS P=1.2e-10 · Best GWAS P=6.37e-10 conditioned to 0.596

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CD79B 0.15 0.16 enet 9 0.17 3.5e-14 -6.0 6.4 1.5e-10 -0.79 0.01 0.99 FALSE
2 GTEx Breast Mammary Tissue (Female) CD79B 0.04 0.07 lasso 2 0.03 4.2e-02 -6.0 6.4 1.2e-10 -0.93 0.02 0.57 TRUE
3 GTEx Cells Transformed fibroblasts PSMC5 0.19 0.09 lasso 5 0.10 7.1e-08 -5.8 -5.3 1.2e-07 0.80 0.02 0.98 FALSE
4 GTEx Esophagus Mucosa STRADA 0.05 0.07 lasso 2 0.05 1.9e-04 -6.0 -6.0 1.8e-09 0.89 0.03 0.92 FALSE
5 GTEx Esophagus Muscularis PSMC5 0.12 0.08 lasso 3 0.07 3.8e-05 -6.0 -5.8 4.8e-09 0.89 0.02 0.96 FALSE
6 GTEx Testis CCDC47 0.17 0.06 enet 28 0.09 1.0e-04 -6.0 5.8 6.5e-09 -0.72 0.03 0.95 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma CD79B 0.02 0.02 lasso 2 0.01 3.0e-03 -6.1 6.1 9.3e-10 -0.72 0.01 0.84 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma SCN4A 0.04 0.01 blup 39 0.03 1.4e-07 -6.1 -5.3 9.0e-08 0.49 0.02 0.96 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma STRADA 0.05 0.03 lasso 1 0.02 1.7e-03 -5.8 -5.8 5.0e-09 0.90 0.00 0.90 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SCN4A 0.05 0.01 blup 41 0.04 2.2e-05 2.4 -6.0 1.5e-09 0.42 0.06 0.74 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma STRADA 0.07 0.01 blup 57 0.03 5.5e-04 2.9 5.3 1.4e-07 -0.85 0.01 0.92 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma STRADA 0.03 0.00 blup 57 0.01 5.2e-02 -5.8 5.7 1.3e-08 -0.88 0.01 0.77 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma PSMC5 0.04 0.03 lasso 1 0.03 5.6e-04 -6.0 -6.0 1.8e-09 0.92 0.01 0.96 FALSE