TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr2:73,169,500-74,565,186
Best TWAS P=3.5e-08 · Best GWAS P=1.2e-07 conditioned to 0.345
73.2M
73.4M
73.6M
73.8M
74M
74.2M
74.4M
74.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
NAT8
0.09
0.12
blup
348
0.13
6.4e-16
4.5
5.5
3.5e-08
0.88
0.04
0.96
TRUE
3
The Cancer Genome Atlas
Colon Adenocarcinoma
ALMS1P
0.08
0.04
blup
42
0.05
5.3e-04
4.7
5.4
7.1e-08
0.83
0.02
0.96
FALSE
2
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
ALMS1P
0.14
0.09
lasso
3
0.08
1.4e-07
4.7
5.2
2.1e-07
0.83
0.01
0.99
FALSE