Best TWAS P=3.5e-08 · Best GWAS P=1.2e-07 conditioned to 0.345
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | NAT8 | 0.09 | 0.12 | blup | 348 | 0.13 | 6.4e-16 | 4.5 | 5.5 | 3.5e-08 | 0.88 | 0.04 | 0.96 | TRUE |
2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ALMS1P | 0.14 | 0.09 | lasso | 3 | 0.08 | 1.4e-07 | 4.7 | 5.2 | 2.1e-07 | 0.83 | 0.01 | 0.99 | FALSE |
3 | The Cancer Genome Atlas | Colon Adenocarcinoma | ALMS1P | 0.08 | 0.04 | blup | 42 | 0.05 | 5.3e-04 | 4.7 | 5.4 | 7.1e-08 | 0.83 | 0.02 | 0.96 | FALSE |