TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr2:147,905,651-149,475,737
Best TWAS P=6.66e-08 · Best GWAS P=5.76e-08 conditioned to 1
148M
148.2M
148.4M
148.6M
148.8M
149M
149.2M
149.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Heart Left Ventricle
ACVR2A
0.07
0.08
lasso
1
0.07
9.3e-05
5.4
5.4
6.7e-08
1.00
0.02
0.97
TRUE
2
GTEx
Testis
ORC4
0.24
0.24
lasso
16
0.24
8.9e-11
5.4
5.4
8.6e-08
0.99
0.02
0.98
FALSE
4
The Cancer Genome Atlas
Breast Invasive Carcinoma
ORC4L
0.04
0.03
enet
7
0.03
5.4e-07
4.6
5.3
1.5e-07
0.80
0.03
0.96
FALSE
3
YFS
Blood
ACVR2A
0.08
0.09
enet
15
0.09
1.5e-27
5.0
5.2
2.1e-07
0.85
0.11
0.89
FALSE