Hub : Genes

CCDC58

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Brain Nucleus accumbens basal ganglia 0.1760 0.0760 6.9e-03 -0.008 NA -0.010 NA -0.010 5.8e-01 NA 8.1e-01 NA 8.1e-01
2 GTEx Esophagus Mucosa 0.1190 0.0470 2.5e-03 0.078 NA 0.044 NA 0.046 6.8e-06 NA 6.6e-04 NA 5.0e-04
3 GTEx Heart Atrial Appendage 0.2210 0.0630 4.0e-05 0.145 NA 0.073 NA 0.128 4.8e-07 NA 3.6e-04 NA 2.3e-06
4 GTEx Heart Left Ventricle 0.1140 0.0456 3.1e-03 0.036 NA 0.006 NA 0.023 5.0e-03 NA 1.4e-01 NA 2.2e-02
5 GTEx Muscle Skeletal 0.0672 0.0271 4.7e-03 0.039 NA 0.025 NA 0.033 9.9e-05 NA 1.6e-03 NA 3.3e-04
6 GTEx Testis 0.1320 0.0520 2.5e-03 0.061 NA 0.090 NA 0.089 1.1e-03 NA 8.7e-05 NA 8.8e-05
7 METSIM Adipose 0.1061 0.0325 6.6e-07 0.060 0.048 0.055 0.051 0.063 2.8e-09 1.0e-07 1.2e-08 3.4e-08 1.1e-09
8 YFS Blood 0.6631 0.0373 0.0e+00 0.486 0.594 0.640 0.560 0.641 8.8e-185 1.3e-249 1.8e-282 1.7e-227 9.0e-283

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.8 1.2 2.5 0.4 -0.4 -1.3 -1.1 -0.8 1.6 0.9 1.6
Bipolar Disorder or Schizophrenia 0.9 2.2 3.8 -0.0 -0.0 -1.3 -1.8 -1.7 1.5 1.9 1.9
Depressed Affect (Nagel 2018) 0.1 0.1 0.3 0.6 -0.5 -0.2 0.2 0.1 0.5 0.0 0.2
Depression (Nagel 2018) 3.7 5.5 9.3 1.6 0.7 -2.4 -2.4 -2.4 3.0 2.3 3.1
Intelligence (Savage-Jansen 2018) 0.2 0.5 2.4 -1.6 -1.2 -0.0 0.2 0.1 -0.7 0.1 0.2
Neuroticism (Nagel 2018) 0.5 1.1 1.9 1.4 0.2 -1.3 -0.9 -0.8 1.4 1.0 0.7
Schizophrenia (2018) 0.6 1.2 2.8 -0.4 0.3 -0.6 -1.4 -1.6 0.7 1.7 1.2
Schizophrenia vs Biploar Disorder 0.5 0.6 1.4 -1.0 -0.3 0.8 0.6 0.1 -1.2 -0.4 -1.2
Worry (Nagel 2018) 0.2 0.4 1.2 0.4 1.1 -0.1 -0.7 -1.0 0.6 0.6 -0.1
Alzheimer’s Disease (in mother) 1.5 1.7 4.4 -0.2 -1.2 0.5 1.9 2.1 -0.7 -1.4 -1.2
Alzheimer’s Disease (in father) 0.5 0.5 1.6 1.2 -0.1 -1.3 -0.5 -0.4 0.3 0.7 0.5
Alzheimer’s Disease (including proxy) 0.4 0.5 1.5 0.3 -0.5 -0.1 1.0 1.2 -0.7 -0.6 -0.8
Crohns Disease (2017) 0.3 0.6 2.1 -1.0 0.4 1.5 -0.2 -0.6 -0.5 0.4 -0.8
Irritable Bowel Disease (IBD) 0.2 0.6 1.4 -1.1 -1.2 0.8 0.5 0.3 -0.9 0.3 -0.5
Ulcerative Colitis (UC) 0.5 0.9 4.4 -0.9 -2.1 -0.4 0.6 0.8 -0.6 0.3 0.3
Major Depression (MDD) 2.7 3.3 5.1 1.5 1.4 -2.3 -2.1 -1.9 1.4 1.7 2.0
Reaction Time 0.9 1.7 6.2 -0.4 -0.5 -2.5 -1.4 -0.9 0.7 0.9 1.6
Verbal and Numeric Reasoning (VNR) 0.3 0.7 2.8 -1.4 -1.7 -0.0 0.6 0.6 -0.2 -0.3 0.2
Breast Cancer 1.1 2.7 5.0 -0.9 -0.7 1.4 1.9 2.0 -1.6 -1.7 -2.2
Ovarian Cancer 0.1 0.1 0.6 -0.4 -0.1 0.8 0.2 0.0 -0.3 -0.1 -0.4
Prostate Cancer 1.8 2.5 4.0 1.3 1.9 -0.9 -1.9 -2.0 1.5 1.3 1.3
Age at First Birth 0.2 0.3 0.8 0.5 0.1 0.1 0.3 0.3 -0.9 -0.6 -0.6
Bipolar Disorder (2011) 1.1 1.1 2.2 -0.4 0.2 -1.0 -1.1 -0.9 1.2 1.5 1.4
Body Mass Index (BMI) (2010) 0.2 0.2 0.7 -0.8 -0.5 -0.4 -0.1 -0.2 -0.5 0.0 0.7
Coronary Artery Disease (CAD) 1.4 1.6 3.3 -0.4 -0.6 0.8 1.5 1.6 -1.8 -1.0 -1.6
Crohns Disease (2012) 0.2 0.3 1.6 0.3 1.2 0.5 -0.4 -0.6 -0.1 0.2 -0.4
Mean Putamen Volume 1.7 1.9 3.9 -2.0 -1.9 0.5 1.4 1.5 -1.2 -0.7 -1.2
Fasting Glucose 0.4 0.4 0.8 -0.5 0.8 0.5 -0.7 -0.9 0.2 0.8 -0.1
HbA1C 0.2 0.2 0.4 0.4 0.3 -0.7 -0.4 -0.3 -0.5 0.3 -0.4
HDL Cholesterol 0.5 0.8 2.1 1.0 -0.4 -1.4 -0.3 0.1 1.4 0.5 1.0
LDL Cholesterol 1.6 2.5 12.9 3.6 1.3 -1.1 -0.5 0.2 1.7 -0.4 1.0
Lupus 1.7 2.6 5.7 -0.5 1.8 -0.9 -2.1 -2.4 0.6 2.2 1.1
Neuroticism (2016) 5.8 8.4 20.5 4.5 2.3 -3.2 -2.6 -2.1 3.2 1.7 2.6
Primary Biliary Cirrhosis 0.8 1.1 3.4 -1.8 0.8 0.2 -0.8 -1.2 0.1 1.7 0.3
Rheumatoid Arthritis 1.5 2.1 3.5 -0.3 -1.8 1.1 1.7 1.9 -1.3 -1.5 -1.3
Schizophrenia (2014) 0.3 0.6 1.5 -0.4 0.0 -0.7 -0.9 -1.0 0.5 1.2 0.8
Triglycerides 0.3 0.5 2.0 0.2 0.0 0.6 0.5 0.7 -0.4 -1.4 -0.8
Type 2 Diabetes (T2D) (2012) 0.6 0.7 2.1 0.1 0.3 -0.3 1.1 1.4 -0.5 -1.1 -0.9
Ulcerative Colitis 0.4 0.6 2.5 0.1 -1.6 -1.1 0.5 0.7 0.1 0.4 0.4
Blood Eosinophil Count 0.5 3.9 12.8 -0.1 -3.6 -1.9 1.6 2.3 -1.6 -1.7 -1.1
Blood Platelet Count 0.1 1.6 6.1 1.7 2.5 1.6 -0.3 -0.7 0.7 0.0 -0.3
Blood Red Count 0.0 0.3 1.1 0.7 0.3 0.7 0.3 0.4 0.4 -1.1 -0.3
Blood White Count 0.4 2.6 4.3 0.1 -0.9 0.8 1.8 2.0 -2.1 -2.0 -2.0
Heel T-Score 0.6 4.5 7.1 2.7 1.2 -2.2 -2.3 -2.0 2.1 1.6 2.5
BMI 0.1 0.6 2.2 -1.5 -0.9 -0.0 -0.1 -0.3 0.1 0.7 1.1
Height 0.2 3.5 16.7 -4.1 -2.4 0.4 -0.2 -0.8 -1.0 1.5 1.1
Waist Hip Ratio (WHR) 0.1 0.6 1.5 -0.1 -1.0 0.1 0.9 1.2 -0.4 -0.9 -0.7
Systolic Blood Pressure 1.7 8.4 28.6 3.4 5.3 0.0 -2.7 -3.1 2.5 1.6 1.1
Smoking Status 1.3 3.0 5.4 -1.1 -1.0 1.4 1.8 1.8 -1.9 -2.3 -2.1
Allergy or Eczema 1.1 2.9 10.3 -2.0 -3.2 -0.4 1.5 1.9 -1.6 -0.9 0.1
Cardiovascular Disease 2.8 9.3 14.5 3.5 3.8 -1.6 -3.1 -3.2 3.3 2.6 2.7
Hypothyroidism (self reported) 0.2 0.6 1.8 -0.9 -1.0 -1.3 0.4 0.7 -0.2 -0.0 0.3
Respiratory disease 0.2 0.4 1.3 -1.0 -1.1 -0.9 -0.0 0.3 -0.2 0.1 0.4
Type 2 Diabetes (T2D) (2018) 0.4 0.7 1.4 1.1 1.2 -0.8 -0.9 -0.6 0.6 0.7 0.4
Lung FEV1/FVC ratio 0.1 0.5 1.3 -1.1 -1.1 0.1 0.2 0.1 -0.7 0.5 0.8
Lung FVC 3.7 18.6 31.9 -1.0 -3.4 3.1 5.2 5.7 -3.7 -5.4 -5.0
Neuroticism 0.4 1.1 1.7 1.1 0.6 -1.3 -1.1 -1.1 1.2 0.9 0.9
Chronotype (morning person) 0.3 0.6 2.6 1.4 1.6 -0.3 -0.5 -0.4 0.1 -0.4 -0.0
Hair Pigment 0.1 3.7 9.2 2.3 3.0 2.1 -1.4 -1.5 1.7 1.2 1.2
Tanning 0.2 2.1 5.9 -0.9 -2.4 0.2 1.6 1.7 -1.3 -1.4 -0.8
Hand grip strength (left) 2.2 5.7 7.2 -2.0 -1.8 2.5 2.7 2.3 -2.7 -2.3 -2.7
Number of treatments/medications taken 5.9 10.6 16.3 2.6 2.1 -3.9 -3.5 -3.1 3.5 2.7 4.0
Average weekly spirits intake 0.4 0.5 2.4 -1.1 -1.6 -0.5 0.0 0.1 -0.2 -0.3 0.1
Sensitivity / hurt feelings 3.6 6.1 9.4 3.0 1.1 -3.1 -2.3 -1.7 3.1 2.2 2.7
Frequency of depressed mood in last 2 weeks 4.6 6.5 12.6 1.6 0.7 -2.5 -2.7 -2.6 3.1 2.5 3.5
Hearing difficulty/problems: Yes 1.2 1.9 4.7 -1.6 -0.4 0.6 1.3 1.3 -2.2 -1.1 -1.6
Relative age of first facial hair 0.1 0.2 0.5 0.7 0.6 0.7 -0.1 -0.0 -0.1 0.4 -0.2
Other serious medical condition/disability diagnosed by doctor 0.1 0.2 0.5 -0.7 -0.7 -0.1 0.3 0.4 -0.3 -0.1 0.3
Ever used hormone-replacement therapy (HRT) 0.4 0.5 0.8 0.7 0.9 0.5 0.4 0.5 0.6 -0.9 -0.8
Ever had hysterectomy (womb removed) 1.2 1.4 3.8 0.6 0.4 -0.8 -1.1 -0.9 1.9 0.9 1.8
Systolic blood pressure, automated reading 1.5 4.3 14.6 2.7 3.8 -0.2 -1.7 -2.0 1.8 1.3 0.7
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.5 0.6 0.5 -0.7 -0.4 -0.2 0.6 -0.3 -0.3
Angina 0.3 0.4 0.9 0.9 0.5 0.2 0.4 0.6 0.9 -0.5 0.3
Medication for hormone replacement therapy 0.4 0.4 1.7 0.3 1.3 0.8 -0.4 -0.5 0.6 0.3 -0.2
Vitamin and mineral supplements 2.1 2.8 6.7 0.7 -0.2 1.5 1.8 2.1 -1.0 -2.6 -2.2
Supplements: Zinc 0.3 0.4 1.5 -1.2 -0.9 0.3 0.3 0.1 -0.5 -0.3 -0.3
Medication: Co-codamol 2.6 3.0 7.3 1.7 -0.3 -2.0 -1.3 -1.0 2.1 1.5 2.7
Medication: Metformin 0.5 0.7 3.6 1.9 0.8 -0.7 -0.1 0.4 0.3 -0.7 -0.2
Diabetes (father) 0.5 0.6 1.2 -0.5 0.1 1.1 0.9 0.9 -0.5 -0.8 -1.0
Diabetes (mother) 1.8 2.3 5.1 -1.2 -0.1 2.3 1.1 0.9 -1.9 -1.2 -2.1
Severe depression (siblings) 0.7 0.7 3.7 -1.9 -1.4 -0.0 0.1 0.0 -0.1 0.1 0.1
Pack years adult smoking proportion 0.9 1.4 4.8 -0.4 0.7 2.2 1.0 0.7 -0.9 -1.1 -1.4
Impedance of leg (right) 0.2 0.8 2.2 0.2 0.1 1.4 0.9 0.9 -0.3 -0.9 -1.5
Leg fat-free mass (left) 0.3 1.5 2.7 -1.6 -1.4 -1.0 -0.9 -1.1 0.5 1.4 1.5
Trunk fat percentage 0.0 0.1 0.4 -0.4 -0.3 -0.0 -0.0 -0.1 0.6 0.4 0.6
Hand grip strength (right) 2.7 7.3 10.1 -2.7 -2.2 2.7 2.8 2.4 -3.2 -2.4 -3.0
Townsend deprivation index at recruitment 0.3 0.5 1.1 0.6 1.1 -0.0 -0.8 -0.8 0.4 0.8 0.3
Current tobacco smoking 1.7 2.8 7.0 -2.6 -1.8 1.9 1.4 1.1 -1.8 -1.1 -1.1
Average weekly fortified wine intake 0.6 0.7 1.9 -0.4 1.0 1.4 0.4 0.2 -0.3 -0.9 -1.3
Maternal smoking around birth 0.1 0.1 0.3 0.1 -0.5 -0.5 0.3 0.4 -0.3 -0.2 -0.2
Fed-up feelings 1.1 2.1 5.2 1.1 -0.6 -1.6 -1.2 -1.2 2.3 0.9 1.9
Frequency of unenthusiasm / disinterest in last 2 weeks 4.6 6.2 10.0 1.4 0.6 -2.4 -2.7 -2.7 2.9 2.8 3.2
Relative age voice broke 0.4 0.7 1.8 0.2 0.4 1.3 0.8 0.7 -1.0 -0.1 -1.1
Taking other prescription medications 7.2 11.2 17.5 1.6 2.0 -3.9 -3.8 -3.5 3.5 3.3 4.2
Age when periods started (menarche) 0.3 0.7 2.0 0.7 -0.3 0.1 0.7 0.8 -0.2 -1.4 -1.4
Bilateral oophorectomy (both ovaries removed) 4.4 5.1 9.9 1.9 1.2 -2.1 -2.3 -2.0 3.1 2.0 3.0
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 4.2 2.0 0.2 -0.5 -0.2 0.1 0.3 -0.3 0.6
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 1.0 0.0 0.1 -0.1 -0.8 -1.0 0.0 1.0 0.1
Qualifications: CSEs or equivalent 1.0 1.3 3.2 1.8 1.6 -0.6 -1.1 -1.1 0.9 0.7 0.4
Serious illness, injury or assault to yourself 0.4 0.5 1.2 -0.0 0.6 -0.3 -0.9 -0.8 1.0 0.5 1.1
High blood pressure 2.5 7.0 12.0 3.5 3.5 -1.6 -2.5 -2.5 3.0 2.0 2.0
Hayfever, allergic rhinitis or eczema 1.1 2.5 7.5 -1.9 -2.7 -0.6 1.3 1.6 -1.8 -0.8 -0.2
Multivitamins +/- minerals 1.0 1.2 3.7 -1.0 -0.1 -0.1 -1.0 -1.3 0.8 1.9 1.4
Stomach or abdominal pain in last month 0.2 0.2 0.5 0.2 0.1 -0.3 -0.6 -0.6 0.7 0.6 0.3
Supplements: Glucosamine 0.3 0.4 1.0 0.4 0.1 -0.8 -0.8 -0.8 0.6 0.3 1.0
Diverticular disease/diverticulitis (self-reported) 0.9 1.0 2.1 -0.2 -0.6 -1.1 -1.0 -0.9 1.4 1.1 1.2
Medication: Atenolol 0.5 0.6 1.8 1.3 0.9 -0.2 -0.5 -0.5 1.1 0.3 0.8
Medication: Levothyroxine sodium 0.3 0.6 2.7 -1.6 -0.4 -0.3 0.8 0.8 -0.2 -0.5 -0.3
Sitting height 0.1 0.9 1.8 -1.4 -1.3 -1.2 -0.7 -0.8 0.1 0.8 0.6
Chronic bronchitis/emphysema (father) 0.2 0.3 0.6 -0.2 0.8 0.6 0.2 0.2 -0.6 -0.5 -0.7
High blood pressure (mother) 0.9 1.3 2.4 -0.6 1.5 0.4 -1.2 -1.5 1.1 1.6 0.8
Body mass index (BMI) 0.1 0.2 0.7 -0.7 -0.8 -0.5 0.1 0.1 -0.1 0.2 0.6
Impedance of leg (left) 0.1 0.6 1.6 0.6 0.4 1.1 0.7 0.8 -0.2 -0.8 -1.3
Leg predicted mass (left) 0.3 1.6 2.6 -1.6 -1.4 -1.0 -1.0 -1.2 0.5 1.5 1.6
Trunk fat mass 0.1 0.3 0.7 -0.8 -0.7 -0.2 -0.2 -0.2 0.6 0.5 0.9
Waist circumference 0.2 0.6 1.9 -0.9 -1.4 -0.8 0.1 0.2 0.3 0.3 1.0
Number of incorrect matches in round 0.8 1.2 2.8 0.8 1.7 -0.6 -1.3 -1.4 0.6 1.3 0.8
Past tobacco smoking 0.1 0.2 0.5 0.6 0.4 0.7 -0.3 -0.5 0.3 0.5 0.2
Alcohol usually taken with meals 0.8 1.2 3.0 -0.6 -1.0 0.5 1.2 0.9 -1.7 -1.1 -1.3
Nervous feelings 2.0 3.6 6.7 1.8 2.6 -1.0 -2.1 -2.1 2.0 1.7 1.5
Frequency of tenseness / restlessness in last 2 weeks 6.3 9.8 18.9 2.6 0.1 -4.4 -3.1 -2.6 3.6 2.7 3.9
Hearing difficulty/problems with background noise 0.2 0.3 0.8 -0.3 -0.8 -0.9 0.4 0.7 -0.2 -0.2 -0.0
Hair/balding pattern: Pattern 2 0.5 0.6 1.8 1.3 0.5 0.2 -0.6 -0.7 1.0 0.7 0.7
Had menopause 1.5 1.9 3.6 0.4 -0.1 0.4 1.5 1.7 -1.6 -1.8 -1.9
Had other major operations 0.4 0.5 1.6 -0.2 1.3 0.1 -0.8 -0.9 0.6 0.3 0.5
Forced vital capacity (FVC) 1.3 5.2 6.3 -2.5 -2.5 2.1 2.3 2.2 -2.0 -1.9 -2.5
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.9 6.0 2.4 0.4 -1.5 -1.0 -0.7 1.3 0.6 1.8
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 4.7 -0.5 -2.2 -1.2 0.5 1.0 0.6 -0.2 0.8
Qualifications: None of the above 2.3 4.9 13.5 3.7 1.6 -2.3 -1.9 -1.2 2.8 1.1 2.0
Financial difficulties in last 2 years 0.1 0.2 0.9 -0.1 0.0 0.9 0.2 -0.1 -0.4 -0.1 -0.4
Mouth/teeth dental problems 0.7 1.1 3.2 0.0 1.8 0.7 -1.1 -1.5 0.7 1.0 0.2
Heart attack 0.2 0.3 1.4 1.2 0.7 -0.1 -0.1 0.1 0.7 -0.4 0.1
Allergy 0.8 1.8 5.6 1.9 2.4 1.0 -0.7 -1.0 1.4 0.3 -0.3
Pain all over the body in last month 0.4 0.5 1.2 -0.3 -0.4 -1.1 -0.6 -0.5 0.7 0.8 0.8
Diabetes (self-reported) 1.0 1.6 3.5 1.9 1.0 -1.5 -1.2 -0.8 1.6 0.2 1.3
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 0.9 -0.5 -0.9 -0.4 0.1 0.2 -0.8 0.2 0.1
Medication: Ramipril 1.3 1.7 5.0 2.2 1.2 -1.1 -0.8 -0.4 1.8 0.4 1.2
Medication: Simvastatin 2.5 3.7 10.1 3.2 2.4 -1.5 -1.5 -1.2 2.2 0.8 1.4
Fluid intelligence score 0.3 0.6 3.4 -1.8 -1.2 0.0 0.0 -0.2 0.1 -0.0 -0.2
Illnesses of siblings 0.1 0.2 0.6 -0.5 0.2 0.6 0.1 -0.1 -0.8 0.3 0.2
Neuroticism score 1.2 2.5 3.4 1.5 0.9 -1.8 -1.8 -1.7 1.9 1.4 1.5
Weight 0.2 0.8 2.1 -1.4 -1.2 -0.7 -0.4 -0.6 0.1 0.9 1.1
Impedance of arm (right) 0.2 1.0 1.7 1.3 1.0 -0.2 -0.9 -1.1 1.2 1.2 0.7
Arm fat percentage (right) 0.1 0.3 0.8 0.1 -0.5 -0.7 -0.2 -0.2 0.6 0.5 0.9
Trunk fat-free mass 0.2 1.3 5.3 -2.1 -2.3 -0.1 0.4 0.2 -0.9 -0.1 0.1
Hip circumference 0.5 2.1 5.3 -0.8 -1.2 -1.6 -1.0 -0.9 1.4 1.7 2.3
Time employed in main current job 2.6 3.0 5.5 -2.3 -2.0 1.1 1.5 1.5 -1.9 -1.3 -2.0
Alcohol intake versus 10 years previously 0.5 0.7 2.1 -0.9 0.1 1.1 0.6 0.3 -1.5 -0.0 -1.0
Father’s age at death 1.3 1.8 3.1 0.0 -0.7 1.0 1.5 1.5 -1.8 -1.6 -1.7
Worrier / anxious feelings 1.2 2.3 3.3 1.5 1.2 -1.8 -1.6 -1.4 1.8 1.4 1.2
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.1 3.3 0.1 -0.4 -1.7 -1.4 -1.4 1.8 1.8 1.8
Falls in the last year 1.1 1.5 5.4 -2.3 -2.2 1.0 0.4 0.1 -0.7 0.4 0.4
Hair/balding pattern: Pattern 3 1.0 1.5 4.0 1.1 2.0 -1.4 -1.3 -1.2 0.9 0.5 0.8
Number of live births 1.5 2.1 8.3 2.9 1.7 -1.3 -0.6 -0.2 1.5 -0.1 0.8
Forced expiratory volume in 1-second (FEV1) 1.3 4.5 7.3 -2.4 -2.7 1.9 2.1 2.0 -1.9 -1.5 -2.2
Pulse rate 4.4 7.5 15.4 -0.9 2.1 -0.9 -3.3 -3.9 1.7 3.9 3.1
Happiness 2.0 2.5 4.5 -0.1 1.3 -1.1 -1.9 -1.9 1.5 2.1 1.7
Noisy workplace 1.4 1.7 2.9 1.0 0.7 -1.7 -1.4 -1.2 1.1 1.5 1.5
Qualifications: A levels/AS levels or equivalent 0.4 0.8 2.7 -1.6 0.5 1.1 -0.2 -0.7 -1.1 0.5 -0.6
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.1 -1.1 -0.2 0.6 0.5 0.2 -0.9 0.2 -0.4
Mouth/teeth dental problems: Dentures 0.7 1.2 3.8 0.5 -0.8 -1.9 -0.8 -0.4 0.8 0.9 1.7
Asthma 0.2 0.3 0.9 -0.9 -0.3 -0.9 -0.5 -0.3 0.1 0.3 0.5
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 2.6 1.6 -0.2 -1.1 -0.1 0.3 0.4 -0.4 0.2
Medication: Cholesterol lowering 3.9 6.1 19.6 4.4 3.1 -2.0 -1.8 -1.2 2.7 0.6 1.8
Depression (self-reported) 4.1 4.9 8.3 0.8 -0.1 -2.2 -2.4 -2.2 2.9 2.7 2.8
Medication: Lansoprazole 0.3 0.3 0.8 0.6 0.2 -0.6 -0.5 -0.4 0.6 0.9 0.7
Prospective memory result 5.7 7.0 9.7 -2.2 -2.4 2.7 3.0 2.8 -3.1 -2.2 -2.5
Lung cancer (father) 0.1 0.1 0.3 -0.3 0.1 0.4 0.1 -0.0 -0.5 -0.2 -0.2
Illnesses of mother 0.5 0.7 1.1 1.1 0.7 -0.9 -0.9 -0.7 0.6 1.0 0.7
Forced expiratory volume in 1-second (FEV1), Best measure 1.4 4.6 7.3 -2.4 -2.7 2.0 2.2 2.1 -2.1 -1.3 -2.0
Pulse wave Arterial Stiffness index 0.7 0.9 2.4 -1.2 0.2 1.0 0.4 0.1 -1.6 -0.7 -1.2
Impedance of arm (left) 0.2 0.9 1.6 0.9 1.1 0.2 -0.8 -1.0 1.2 1.1 0.5
Arm fat mass (right) 0.1 0.3 0.8 -0.8 -0.9 -0.4 -0.0 -0.1 0.2 0.5 0.8
Trunk predicted mass 0.2 1.3 5.0 -2.1 -2.2 -0.0 0.3 0.2 -0.8 -0.0 0.2
Standing height 0.1 1.3 4.5 -2.1 -1.4 -0.1 -0.7 -1.1 0.1 1.2 0.8
Length of working week for main job 0.7 0.8 1.9 0.0 0.3 -1.4 -1.1 -1.0 0.7 1.2 0.7
Exposure to tobacco smoke at home 0.1 0.2 0.6 -0.0 -0.1 0.8 0.4 0.3 0.5 -0.3 -0.2
Breastfed as a baby 1.6 1.9 2.9 1.1 0.3 -1.5 -1.7 -1.7 1.4 1.2 1.7
Tense / ‘highly strung’ 1.2 2.0 2.9 1.0 1.5 -1.1 -1.5 -1.7 1.5 1.6 1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 2.3 3.5 8.0 1.9 -0.4 -2.8 -1.7 -1.3 2.0 1.4 2.4
Hair/balding pattern: Pattern 4 0.4 1.0 3.5 0.5 1.9 0.7 -1.1 -1.2 0.8 0.7 0.1
Birth weight of first child 0.2 0.4 1.3 -1.1 -1.0 0.3 0.1 -0.0 0.5 0.5 0.7
Peak expiratory flow (PEF) 0.7 1.7 4.1 -2.0 -1.9 0.9 0.9 0.7 -1.4 -0.6 -1.3
Pulse wave reflection index 4.2 5.2 7.6 -1.4 -2.0 1.7 2.5 2.3 -2.8 -2.7 -2.5
Ever highly irritable/argumentative for 2 days 0.5 0.5 1.3 -0.7 -1.1 -0.7 -0.4 -0.4 -0.1 1.0 0.8
Loud music exposure frequency 1.0 1.1 2.9 -1.5 -0.8 1.2 0.7 0.4 -1.7 -0.5 -0.9
Qualifications: O levels/GCSEs or equivalent 1.0 1.5 8.2 -2.9 -0.6 0.1 -0.6 -1.1 -0.8 1.2 0.1
Mouth/teeth dental problems: Bleeding gums 2.2 2.8 4.1 -1.7 -1.2 1.2 1.7 1.6 -2.0 -1.9 -2.0
Blood clot in the leg (DVT) 0.2 0.3 0.7 -0.5 0.2 -0.0 -0.7 -0.7 0.3 0.6 0.9
Medication: Paracetamol 2.1 3.4 7.8 1.5 2.8 -0.4 -2.0 -2.2 1.7 2.1 1.2
Headache pain in last month 0.1 0.1 0.4 0.3 0.2 0.0 -0.3 -0.3 0.2 0.6 0.2
Medication for cholesterol, blood pressure or diabetes 2.5 4.2 10.6 -3.3 -2.9 1.4 1.8 1.5 -2.1 -0.6 -1.4
Glaucoma (self-reported) 0.2 0.3 0.7 0.0 0.6 0.4 0.4 0.4 -0.8 -0.2 -0.6
Gout (self-reported) 0.0 0.0 0.0 -0.2 0.0 0.0 0.1 0.1 -0.1 0.1 -0.2
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 2.6 -1.6 -0.8 -0.3 1.2 1.2 -0.8 -0.9 -0.8
Medication: Amlodipine 1.3 1.8 5.8 1.5 2.4 0.1 -1.3 -1.4 1.4 0.8 0.5
Medication: Ventolin 100micrograms inhaler 0.4 0.5 2.3 -1.5 -0.9 -0.1 -0.4 -0.3 0.0 0.6 0.4
Birth weight 0.2 0.4 1.0 -0.6 1.0 0.5 -0.7 -0.8 0.0 0.5 0.0
Chronic bronchitis/emphysema (mother) 0.8 1.0 2.0 0.8 0.9 -1.3 -0.9 -0.9 0.6 1.4 0.7
High blood pressure (siblings) 0.4 0.6 1.4 0.0 0.5 -0.7 -0.9 -0.9 1.2 0.7 0.6
Forced vital capacity (FVC), Best measure 1.5 5.4 7.4 -2.4 -2.7 2.0 2.5 2.4 -2.4 -1.8 -2.3
Body fat percentage 0.1 0.2 0.6 -0.3 -0.4 -0.3 -0.1 -0.2 0.6 0.4 0.8
Leg fat percentage (right) 0.1 0.3 0.8 0.2 -0.5 -0.7 -0.2 -0.1 0.8 0.3 0.9
Arm fat-free mass (right) 0.3 1.4 6.3 -2.5 -2.1 0.1 0.3 0.0 -0.6 0.1 0.3
Exposure to tobacco smoke outside home 3.7 4.9 6.6 2.4 1.8 -2.0 -2.5 -2.6 1.9 2.1 2.3
Comparative body size at age 10 0.3 0.8 1.6 -1.3 0.1 1.1 0.8 0.6 -1.2 -0.9 -0.8
Number of full brothers 0.2 0.2 0.4 -0.6 0.0 0.5 -0.3 -0.6 0.6 0.6 0.2
Worry too long after embarrassment 0.1 0.2 0.7 -0.0 -0.6 -0.8 0.1 0.2 0.0 0.3 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 2.3 0.3 0.4 -1.4 -1.5 -1.4 0.7 1.4 1.2
Wheeze or whistling in the chest in last year 0.8 1.4 2.9 0.4 0.7 -1.4 -1.5 -1.4 0.6 1.7 1.1
Number of children fathered 1.0 1.2 2.1 0.5 -0.4 0.7 1.2 1.2 -1.4 -1.3 -1.4
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.5 0.6 1.6 0.6 -0.9 -1.1 0.5 0.8 0.3
Age at first live birth 2.8 4.9 11.1 -3.3 -2.0 2.3 1.8 1.4 -2.5 -1.9 -1.8
Pulse wave peak to peak time 0.5 0.6 1.8 0.8 -0.4 -0.7 -0.3 -0.0 1.3 0.7 1.1
Health satisfaction 0.4 0.5 1.0 0.2 0.8 -0.6 -0.7 -0.5 0.6 1.0 1.0
Shortness of breath walking on level ground 0.3 0.4 1.4 -1.2 -0.3 0.2 0.4 0.4 -0.8 -0.1 -0.6
Qualifications: College or University degree 0.4 1.2 4.8 -2.2 -0.7 1.0 0.6 0.1 -1.6 0.1 -0.4
Eye problems/disorders: None of the above 0.1 0.2 0.4 -0.6 -0.0 0.1 -0.3 -0.6 -0.2 0.6 0.1
Mouth/teeth dental problems: Loose teeth 1.7 2.0 6.1 0.4 -1.0 0.2 1.6 2.1 -0.9 -2.5 -1.1
Emphysema/chronic bronchitis 0.1 0.1 0.3 -0.6 -0.6 0.4 0.2 0.3 -0.2 -0.2 -0.0
Medication for pain relief, constipation, heartburn 3.0 5.1 6.3 -2.5 -2.5 2.0 2.5 2.2 -2.1 -2.0 -2.3
Neck or shoulder pain in last month 0.1 0.1 0.7 0.1 -0.9 -0.4 -0.3 -0.2 0.1 0.2 0.2
Medication: Blood pressure 1.2 2.1 4.8 2.1 2.2 -0.9 -1.3 -1.2 1.8 0.2 0.7
Angina (self-reported) 0.4 0.5 1.1 0.8 0.2 0.4 0.7 1.0 0.7 -1.0 -0.0
Migraine (self-reported) 0.5 0.6 1.5 1.1 0.5 -0.8 -0.4 -0.2 1.2 -0.0 1.0
Medication: Ibuprofen 0.4 0.5 1.8 1.3 -0.7 -0.7 0.2 0.5 0.3 -0.7 -0.1
Medication: Allopurinol 0.3 0.4 0.8 0.5 0.2 -0.9 -0.6 -0.5 0.7 0.6 0.9
Medication: Omeprazole 3.5 4.2 5.7 1.8 2.2 -2.0 -2.2 -2.1 2.4 1.8 1.8
Medication: Seretide 50 evohaler 1.6 1.8 3.0 -0.2 -0.5 -1.6 -1.7 -1.6 1.4 1.3 1.7
Mean time to correctly identify matches 0.9 1.7 7.4 0.2 0.0 -2.7 -1.3 -0.9 0.8 0.5 1.7
Heart disease (mother) 1.1 1.3 3.6 -1.1 0.1 1.9 1.2 0.7 -1.1 -1.0 -1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 1.9 3.9 1.1 1.6 -0.5 -1.8 -2.0 1.1 1.2 1.2
Whole body fat mass 0.1 0.4 0.8 -0.9 -0.8 -0.3 -0.2 -0.3 0.5 0.5 0.9
Leg fat mass (right) 0.2 0.9 2.5 -0.2 -0.5 -1.1 -0.8 -0.8 1.0 1.0 1.6
Arm predicted mass (right) 0.2 1.1 5.2 -2.3 -1.9 0.0 0.2 0.1 -0.5 0.0 0.3
Pulse rate, automated reading 9.6 31.0 54.8 2.3 6.2 -2.7 -6.6 -7.4 3.9 7.1 5.7
Alcohol intake frequency. 0.0 0.1 0.4 0.1 0.3 0.6 -0.0 -0.1 -0.5 0.0 -0.3
Comparative height size at age 10 0.3 1.9 6.1 -2.5 -1.5 -0.8 -0.9 -1.2 0.0 1.4 1.4
Number of full sisters 3.3 4.0 6.8 1.6 1.0 -1.3 -2.3 -2.4 2.6 2.2 1.9
Suffer from ‘nerves’ 0.1 0.2 0.3 -0.4 -0.3 0.4 0.5 0.6 -0.3 -0.4 -0.5
Overall health rating 1.4 3.1 4.9 0.5 1.1 -1.5 -2.1 -2.2 1.9 1.9 2.0
Chest pain or discomfort 1.5 2.2 3.6 0.7 1.1 -1.3 -1.7 -1.5 1.9 1.8 1.5
Had major operations 0.3 0.4 1.0 0.8 0.3 -0.3 0.4 0.5 -0.7 -1.0 -0.4
Age at last live birth 0.6 0.8 2.1 -1.0 -0.2 1.4 0.7 0.5 -1.3 -0.8 -0.8
Family relationship satisfaction 3.8 4.7 6.4 0.8 2.0 -1.4 -2.5 -2.5 2.3 2.5 2.5
Leg pain on walking 1.0 1.3 2.4 -0.1 -1.4 1.0 1.5 1.6 -1.2 -0.9 -0.7
Qualifications: NVQ or HND or HNC or equivalent 2.6 3.1 5.9 0.6 1.4 -0.9 -2.0 -2.2 1.7 2.4 2.0
Commuting to job workplace: Car/motor vehicle 0.7 0.8 3.4 -0.1 -1.8 -1.0 0.2 0.6 0.8 -0.7 0.6
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.0 0.6 0.9 -0.9 -0.7 -0.6 1.0 0.8 0.6
Medication: Aspirin 0.9 1.2 2.8 1.2 1.1 -0.6 -1.0 -0.7 1.2 0.6 1.7
Supplements: Vitamin C 0.3 0.3 1.1 -0.8 -1.1 -0.3 0.1 -0.2 -0.6 0.5 0.4
Knee pain experienced in last month 0.7 1.1 2.4 0.6 0.3 -0.4 -1.1 -1.4 1.1 1.1 1.5
Hypertension (Self-reported) 3.1 8.6 14.8 3.8 3.8 -1.7 -2.8 -2.8 3.3 2.2 2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.6 3.0 5.7 0.5 1.4 -1.7 -2.0 -2.0 1.5 2.4 1.7
Illnesses of father: Heart disease 0.9 1.3 4.2 -0.8 -2.0 0.4 1.2 1.3 -0.5 -1.4 -0.3
Illnesses of siblings: Diabetes 0.6 0.8 2.0 0.2 -1.1 -0.3 1.0 1.4 -0.6 -0.7 -1.0
Smoking status: Previous 0.2 0.3 1.5 0.6 0.4 -1.2 -0.2 0.2 0.6 -0.5 0.0
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 2.4 -1.5 -1.4 -0.4 -0.4 -0.5 0.2 1.1 0.6
Whole body fat-free mass 0.2 1.3 4.8 -2.2 -2.1 -0.4 -0.1 -0.3 -0.4 0.5 0.7
Leg fat-free mass (right) 0.3 1.8 3.1 -1.6 -1.3 -1.2 -1.1 -1.3 0.5 1.6 1.7
Arm fat percentage (left) 0.1 0.3 0.7 -0.2 -0.5 -0.5 -0.2 -0.2 0.7 0.5 0.8
Average weekly red wine intake 0.5 0.8 2.0 -0.1 -0.9 -0.5 0.9 1.2 -0.5 -1.4 -0.7
Handedness (chirality/laterality): Left-handed 5.7 6.9 9.4 2.4 2.4 -1.7 -3.0 -3.0 3.1 2.4 2.7
Mood swings 0.5 1.0 1.6 1.2 0.0 -1.2 -0.8 -0.7 1.3 0.9 1.3
Loneliness, isolation 0.8 1.1 3.0 -0.2 1.1 0.1 -1.4 -1.7 0.5 1.4 0.7
Long-standing illness, disability or infirmity 1.4 2.2 4.5 -0.6 0.4 -2.1 -1.6 -1.5 1.1 1.8 1.8
Ever had bowel cancer screening 0.6 0.8 1.7 -0.6 1.0 -0.6 -1.0 -1.3 0.0 1.0 0.7
Diabetes diagnosed by doctor 1.0 1.6 4.0 2.0 1.2 -1.4 -1.2 -0.8 1.4 0.5 1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.3 1.0 -1.0 0.0 0.9 0.1 -0.2 -0.4 -0.0 0.0
Friendships satisfaction 0.6 0.8 1.1 -0.0 1.1 -0.3 -1.0 -1.0 1.0 1.0 0.9
Qualifications: nursing, teaching 0.9 1.5 4.2 -2.1 -0.6 1.4 0.9 0.5 -1.6 -0.3 -1.2
Commuting to job workplace: Walk 0.6 0.6 3.1 -0.5 0.6 1.8 0.4 0.1 -0.7 -0.1 -0.6
Eye problems/disorders: Cataract 1.7 2.0 3.8 -0.1 -0.9 1.2 1.9 1.9 -1.0 -1.9 -1.4
Mouth/teeth dental problems: Mouth ulcers 1.2 2.0 3.6 0.3 -0.4 1.2 1.8 1.9 -1.3 -1.5 -1.8
Medication for cholesterol 3.3 5.0 6.5 -2.0 -2.5 1.3 2.5 2.5 -2.5 -2.4 -2.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.8 1.4 -0.4 1.1 -0.4 -0.9 -1.1 0.4 0.9 1.2
Back pain experienced in last month 0.4 0.5 2.4 0.3 -1.6 -0.7 0.1 0.3 0.9 0.2 0.4
Mineral and other dietary supplements 0.7 0.9 2.0 -0.0 0.6 1.4 0.9 0.9 -0.2 -1.1 -1.3
Breast cancer (self-reported) 0.2 0.3 1.4 -0.1 1.2 0.8 -0.1 -0.2 -0.1 0.0 -0.5
Asthma (self-reported) 0.2 0.3 0.9 -0.9 -0.6 -1.0 -0.3 -0.1 0.1 0.2 0.4
Osteoporosis (self-reported) 1.6 2.0 3.8 -0.1 1.2 -2.0 -1.5 -1.4 0.9 1.9 1.5
Osteoarthritis (self-reported) 2.6 3.4 6.6 1.4 1.4 -1.1 -2.0 -2.1 1.4 2.1 2.6
Medication: Aspirin 0.8 1.1 2.4 1.5 1.0 -0.6 -0.8 -0.4 1.3 0.3 1.5
Medication: Gliclazide 1.6 1.8 3.6 0.1 -0.8 1.3 1.5 1.5 -1.2 -1.9 -1.5
Illnesses of father: None of the above (group 1) 1.2 1.4 3.4 0.3 1.7 -0.1 -1.2 -1.4 0.9 1.9 0.9
Smoking status: Current 2.0 3.1 7.0 -2.6 -1.8 1.9 1.5 1.1 -2.1 -1.1 -1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.7 3.7 6.4 -0.5 -1.5 2.5 2.4 2.2 -1.2 -2.0 -2.1
Whole body water mass 0.2 1.2 4.5 -2.1 -2.1 -0.5 -0.0 -0.2 -0.5 0.4 0.6
Leg predicted mass (right) 0.3 1.6 2.7 -1.6 -1.3 -1.1 -1.0 -1.2 0.5 1.5 1.6
Arm fat mass (left) 0.1 0.3 1.0 -1.0 -1.0 -0.2 0.1 0.0 0.1 0.3 0.6
Number of self-reported non-cancer illnesses 5.5 9.5 15.3 1.8 1.5 -3.9 -3.4 -3.1 2.9 3.5 3.7
Average weekly champagne plus white wine intake 1.5 2.0 3.8 -0.2 -0.8 1.0 2.0 1.9 -1.5 -1.4 -1.7
Miserableness 0.7 1.2 2.8 0.9 -1.2 -1.7 -0.5 -0.1 1.6 0.4 1.2
Guilty feelings 0.1 0.1 0.4 -0.3 0.3 -0.1 -0.4 -0.6 -0.5 0.3 0.1
Wears glasses or contact lenses 0.6 0.7 3.0 -0.8 -0.9 -1.7 -0.3 -0.1 0.2 0.6 0.8
Ever taken oral contraceptive pill 0.6 0.7 2.7 -1.6 -1.4 -0.2 0.3 0.3 -0.6 -0.4 0.1
Hearing aid user 1.3 1.5 4.0 -2.0 -1.8 0.7 0.9 0.9 -1.4 -0.6 -0.3
Mother’s age at death 2.7 3.4 8.9 -0.7 0.1 3.0 1.9 1.7 -1.3 -1.8 -2.5
Financial situation satisfaction 0.6 0.8 3.4 -1.8 -0.9 1.1 0.5 0.2 -0.8 0.2 -0.0
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.4 -0.3 -0.9 -1.1 -0.4 -0.1 0.9 0.5 1.2
Commuting to job workplace: Public transport 0.4 0.5 1.2 -1.1 -0.1 1.0 0.3 -0.1 -0.9 0.4 -0.6
Eye problems/disorders: Glaucoma 0.6 0.7 1.9 0.8 1.4 -0.4 -0.9 -0.8 0.6 0.9 0.4
Medication: Blood pressure 3.3 6.4 11.8 2.3 3.4 -1.7 -2.7 -2.8 2.1 2.6 2.2
Pain type(s) experienced in last month: Hip pain 0.5 0.6 1.2 -0.9 -0.7 -0.4 -0.6 -0.8 -0.0 0.9 1.1
Supplements: Fish oil (including cod liver oil) 0.1 0.2 0.8 -0.5 -0.9 -0.3 -0.0 -0.1 -0.4 0.0 0.3
High cholesterol (Self-reported) 1.6 2.8 11.3 3.4 2.2 -0.9 -1.0 -0.8 1.7 0.2 1.0
Medication: Bendroflumethiazide 5.6 8.5 11.3 2.3 3.2 -1.8 -3.2 -3.4 2.7 3.3 3.2
Medication: Paracetamol 2.2 3.4 6.1 0.6 2.2 -0.6 -2.2 -2.5 1.8 2.2 1.7
Medication: Lisinopril 1.1 1.4 3.0 1.7 0.8 -0.7 -1.1 -1.1 1.6 0.7 1.4
Medication: Atorvastatin 0.4 0.4 1.8 1.3 0.9 -0.4 -0.3 -0.0 0.6 -0.4 0.5
Illnesses of father: High blood pressure 1.3 1.6 3.7 0.1 -0.1 1.3 1.1 1.1 -1.3 -1.9 -1.8
Alcohol drinker status: Never 0.3 0.3 1.5 0.3 0.4 1.2 0.3 0.4 -0.3 -0.5 -0.5
Ever smoked 0.2 0.3 1.1 -1.0 -0.6 -0.2 0.6 0.6 -0.6 -0.4 -0.2
Basal metabolic rate 0.2 1.1 4.0 -2.0 -1.9 -0.5 -0.2 -0.4 -0.3 0.7 0.8
Leg fat percentage (left) 0.1 0.4 1.0 0.4 -0.3 -0.8 -0.2 -0.1 0.9 0.3 1.0
Arm fat-free mass (left) 0.2 1.2 4.8 -2.2 -2.0 -0.3 0.2 0.0 -0.8 0.3 0.5
Number of operations (self-reported) 0.2 0.3 0.6 0.8 0.4 -0.6 -0.2 -0.1 0.7 -0.3 0.6
Average weekly beer plus cider intake 0.1 0.1 0.3 0.2 0.5 0.1 -0.3 -0.1 0.5 0.2 -0.1
Irritability 0.7 1.2 1.6 1.1 1.1 -1.1 -1.3 -1.2 1.1 1.1 0.8
Risk taking 1.6 2.3 2.9 -1.6 -1.7 1.4 1.6 1.7 -1.2 -1.5 -1.3
Ever had prostate specific antigen (PSA) test 0.3 0.4 1.7 -0.7 -0.8 -0.4 0.2 0.0 -1.3 -0.0 -0.1
Fractured/broken bones in last 5 years 1.2 1.6 2.7 -0.1 -1.3 -0.2 1.3 1.6 -1.5 -1.5 -1.5
Age started oral contraceptive pill 2.7 3.3 5.3 -0.8 -1.1 2.2 2.2 2.0 -1.2 -2.3 -2.0
Diastolic blood pressure, automated reading 3.6 11.3 27.1 2.6 5.2 -0.3 -3.7 -4.3 2.6 3.5 2.3
Ever depressed for a whole week 0.6 0.7 2.7 -1.1 -1.6 -0.9 0.3 0.5 -0.8 -0.2 0.1
Unable to work because of sickness or disability 2.7 3.5 6.0 -0.1 1.0 -2.0 -2.5 -2.4 1.3 2.0 2.2
Commuting to job workplace: Cycle 1.9 2.2 5.9 -1.3 -1.2 1.0 1.4 1.1 -2.4 -1.0 -1.9
Myopia 0.5 0.7 1.8 -0.5 0.7 0.9 0.5 0.3 -1.1 -0.6 -1.3
Vascular/heart problems diagnosed by doctor 2.5 6.9 12.6 -3.5 -3.5 1.6 2.4 2.4 -2.9 -1.8 -2.0
Cholesterol lowering medication 0.7 1.1 2.9 1.7 0.6 -1.1 -0.8 -0.5 1.3 0.7 1.1
Medication: Omeprazole (e.g. Zanprol) 3.5 4.2 6.1 1.3 2.5 -1.7 -2.3 -2.4 2.0 2.2 1.9
Pain experienced in last month 1.2 2.0 3.8 -1.5 0.5 2.0 1.3 1.0 -1.9 -1.0 -1.6
Supplements: Calcium 1.6 1.7 6.2 -2.5 -2.4 -0.0 0.7 0.5 -1.1 -0.1 -0.5
Basal cell carcinoma (self-reported) 1.3 1.6 8.3 0.6 2.9 1.7 -0.1 -0.5 -0.2 -0.2 -0.7
Heart attack/myocardial infarction (self-reported) 0.5 0.6 2.5 1.6 0.9 -0.5 -0.4 -0.1 1.0 -0.2 0.5
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 0.6 -0.6 0.3 0.1 -0.6 -0.6 0.3 0.6 0.7
Heart disease (siblings) 0.5 0.6 1.8 1.1 -0.3 -1.0 -0.2 0.3 1.4 -0.2 0.7
Alcohol drinker status: Previous 1.1 1.3 2.3 -0.2 -0.0 -1.5 -1.3 -1.2 1.1 1.3 1.4
Pack years of smoking 1.4 2.1 5.7 -0.3 0.7 2.4 1.4 1.2 -1.1 -1.7 -1.7
Impedance of whole body 0.1 0.3 0.7 0.7 0.8 0.8 -0.1 -0.2 0.6 0.2 -0.5
Leg fat mass (left) 0.2 0.8 2.3 -0.2 -0.6 -1.1 -0.7 -0.7 0.9 0.9 1.5
Arm predicted mass (left) 0.3 1.4 5.3 -2.3 -2.2 -0.3 0.3 0.1 -0.8 0.1 0.5