Hub : Genes

CCDC58

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Nucleus accumbens basal ganglia	0.1760	0.0760	6.9e-03	-0.008	NA	-0.010	NA	-0.010	5.8e-01	NA	8.1e-01	NA	8.1e-01
2	GTEx	Esophagus Mucosa	0.1190	0.0470	2.5e-03	0.078	NA	0.044	NA	0.046	6.8e-06	NA	6.6e-04	NA	5.0e-04
3	GTEx	Heart Atrial Appendage	0.2210	0.0630	4.0e-05	0.145	NA	0.073	NA	0.128	4.8e-07	NA	3.6e-04	NA	2.3e-06
4	GTEx	Heart Left Ventricle	0.1140	0.0456	3.1e-03	0.036	NA	0.006	NA	0.023	5.0e-03	NA	1.4e-01	NA	2.2e-02
5	GTEx	Muscle Skeletal	0.0672	0.0271	4.7e-03	0.039	NA	0.025	NA	0.033	9.9e-05	NA	1.6e-03	NA	3.3e-04
6	GTEx	Testis	0.1320	0.0520	2.5e-03	0.061	NA	0.090	NA	0.089	1.1e-03	NA	8.7e-05	NA	8.8e-05
7	METSIM	Adipose	0.1061	0.0325	6.6e-07	0.060	0.048	0.055	0.051	0.063	2.8e-09	1.0e-07	1.2e-08	3.4e-08	1.1e-09
8	YFS	Blood	0.6631	0.0373	0.0e+00	0.486	0.594	0.640	0.560	0.641	8.8e-185	1.3e-249	1.8e-282	1.7e-227	9.0e-283

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.8	1.2	2.5	0.4	-0.4	-1.3	-1.1	-0.8	1.6	0.9	1.6
Bipolar Disorder or Schizophrenia	0.9	2.2	3.8	-0.0	-0.0	-1.3	-1.8	-1.7	1.5	1.9	1.9
Depressed Affect (Nagel 2018)	0.1	0.1	0.3	0.6	-0.5	-0.2	0.2	0.1	0.5	0.0	0.2
Depression (Nagel 2018)	3.7	5.5	9.3	1.6	0.7	-2.4	-2.4	-2.4	3.0	2.3	3.1
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.4	-1.6	-1.2	-0.0	0.2	0.1	-0.7	0.1	0.2
Neuroticism (Nagel 2018)	0.5	1.1	1.9	1.4	0.2	-1.3	-0.9	-0.8	1.4	1.0	0.7
Schizophrenia (2018)	0.6	1.2	2.8	-0.4	0.3	-0.6	-1.4	-1.6	0.7	1.7	1.2
Schizophrenia vs Biploar Disorder	0.5	0.6	1.4	-1.0	-0.3	0.8	0.6	0.1	-1.2	-0.4	-1.2
Worry (Nagel 2018)	0.2	0.4	1.2	0.4	1.1	-0.1	-0.7	-1.0	0.6	0.6	-0.1
Alzheimer’s Disease (in mother)	1.5	1.7	4.4	-0.2	-1.2	0.5	1.9	2.1	-0.7	-1.4	-1.2
Alzheimer’s Disease (in father)	0.5	0.5	1.6	1.2	-0.1	-1.3	-0.5	-0.4	0.3	0.7	0.5
Alzheimer’s Disease (including proxy)	0.4	0.5	1.5	0.3	-0.5	-0.1	1.0	1.2	-0.7	-0.6	-0.8
Crohns Disease (2017)	0.3	0.6	2.1	-1.0	0.4	1.5	-0.2	-0.6	-0.5	0.4	-0.8
Irritable Bowel Disease (IBD)	0.2	0.6	1.4	-1.1	-1.2	0.8	0.5	0.3	-0.9	0.3	-0.5
Ulcerative Colitis (UC)	0.5	0.9	4.4	-0.9	-2.1	-0.4	0.6	0.8	-0.6	0.3	0.3
Major Depression (MDD)	2.7	3.3	5.1	1.5	1.4	-2.3	-2.1	-1.9	1.4	1.7	2.0
Reaction Time	0.9	1.7	6.2	-0.4	-0.5	-2.5	-1.4	-0.9	0.7	0.9	1.6
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.8	-1.4	-1.7	-0.0	0.6	0.6	-0.2	-0.3	0.2
Breast Cancer	1.1	2.7	5.0	-0.9	-0.7	1.4	1.9	2.0	-1.6	-1.7	-2.2
Ovarian Cancer	0.1	0.1	0.6	-0.4	-0.1	0.8	0.2	0.0	-0.3	-0.1	-0.4
Prostate Cancer	1.8	2.5	4.0	1.3	1.9	-0.9	-1.9	-2.0	1.5	1.3	1.3
Age at First Birth	0.2	0.3	0.8	0.5	0.1	0.1	0.3	0.3	-0.9	-0.6	-0.6
Bipolar Disorder (2011)	1.1	1.1	2.2	-0.4	0.2	-1.0	-1.1	-0.9	1.2	1.5	1.4
Body Mass Index (BMI) (2010)	0.2	0.2	0.7	-0.8	-0.5	-0.4	-0.1	-0.2	-0.5	0.0	0.7
Coronary Artery Disease (CAD)	1.4	1.6	3.3	-0.4	-0.6	0.8	1.5	1.6	-1.8	-1.0	-1.6
Crohns Disease (2012)	0.2	0.3	1.6	0.3	1.2	0.5	-0.4	-0.6	-0.1	0.2	-0.4
Mean Putamen Volume	1.7	1.9	3.9	-2.0	-1.9	0.5	1.4	1.5	-1.2	-0.7	-1.2
Fasting Glucose	0.4	0.4	0.8	-0.5	0.8	0.5	-0.7	-0.9	0.2	0.8	-0.1
HbA1C	0.2	0.2	0.4	0.4	0.3	-0.7	-0.4	-0.3	-0.5	0.3	-0.4
HDL Cholesterol	0.5	0.8	2.1	1.0	-0.4	-1.4	-0.3	0.1	1.4	0.5	1.0
LDL Cholesterol	1.6	2.5	12.9	3.6	1.3	-1.1	-0.5	0.2	1.7	-0.4	1.0
Lupus	1.7	2.6	5.7	-0.5	1.8	-0.9	-2.1	-2.4	0.6	2.2	1.1
Neuroticism (2016)	5.8	8.4	20.5	4.5	2.3	-3.2	-2.6	-2.1	3.2	1.7	2.6
Primary Biliary Cirrhosis	0.8	1.1	3.4	-1.8	0.8	0.2	-0.8	-1.2	0.1	1.7	0.3
Rheumatoid Arthritis	1.5	2.1	3.5	-0.3	-1.8	1.1	1.7	1.9	-1.3	-1.5	-1.3
Schizophrenia (2014)	0.3	0.6	1.5	-0.4	0.0	-0.7	-0.9	-1.0	0.5	1.2	0.8
Triglycerides	0.3	0.5	2.0	0.2	0.0	0.6	0.5	0.7	-0.4	-1.4	-0.8
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.1	0.1	0.3	-0.3	1.1	1.4	-0.5	-1.1	-0.9
Ulcerative Colitis	0.4	0.6	2.5	0.1	-1.6	-1.1	0.5	0.7	0.1	0.4	0.4
Blood Eosinophil Count	0.5	3.9	12.8	-0.1	-3.6	-1.9	1.6	2.3	-1.6	-1.7	-1.1
Blood Platelet Count	0.1	1.6	6.1	1.7	2.5	1.6	-0.3	-0.7	0.7	0.0	-0.3
Blood Red Count	0.0	0.3	1.1	0.7	0.3	0.7	0.3	0.4	0.4	-1.1	-0.3
Blood White Count	0.4	2.6	4.3	0.1	-0.9	0.8	1.8	2.0	-2.1	-2.0	-2.0
Heel T-Score	0.6	4.5	7.1	2.7	1.2	-2.2	-2.3	-2.0	2.1	1.6	2.5
BMI	0.1	0.6	2.2	-1.5	-0.9	-0.0	-0.1	-0.3	0.1	0.7	1.1
Height	0.2	3.5	16.7	-4.1	-2.4	0.4	-0.2	-0.8	-1.0	1.5	1.1
Waist Hip Ratio (WHR)	0.1	0.6	1.5	-0.1	-1.0	0.1	0.9	1.2	-0.4	-0.9	-0.7
Systolic Blood Pressure	1.7	8.4	28.6	3.4	5.3	0.0	-2.7	-3.1	2.5	1.6	1.1
Smoking Status	1.3	3.0	5.4	-1.1	-1.0	1.4	1.8	1.8	-1.9	-2.3	-2.1
Allergy or Eczema	1.1	2.9	10.3	-2.0	-3.2	-0.4	1.5	1.9	-1.6	-0.9	0.1
Cardiovascular Disease	2.8	9.3	14.5	3.5	3.8	-1.6	-3.1	-3.2	3.3	2.6	2.7
Hypothyroidism (self reported)	0.2	0.6	1.8	-0.9	-1.0	-1.3	0.4	0.7	-0.2	-0.0	0.3
Respiratory disease	0.2	0.4	1.3	-1.0	-1.1	-0.9	-0.0	0.3	-0.2	0.1	0.4
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.4	1.1	1.2	-0.8	-0.9	-0.6	0.6	0.7	0.4
Lung FEV1/FVC ratio	0.1	0.5	1.3	-1.1	-1.1	0.1	0.2	0.1	-0.7	0.5	0.8
Lung FVC	3.7	18.6	31.9	-1.0	-3.4	3.1	5.2	5.7	-3.7	-5.4	-5.0
Neuroticism	0.4	1.1	1.7	1.1	0.6	-1.3	-1.1	-1.1	1.2	0.9	0.9
Chronotype (morning person)	0.3	0.6	2.6	1.4	1.6	-0.3	-0.5	-0.4	0.1	-0.4	-0.0
Hair Pigment	0.1	3.7	9.2	2.3	3.0	2.1	-1.4	-1.5	1.7	1.2	1.2
Tanning	0.2	2.1	5.9	-0.9	-2.4	0.2	1.6	1.7	-1.3	-1.4	-0.8
Hand grip strength (left)	2.2	5.7	7.2	-2.0	-1.8	2.5	2.7	2.3	-2.7	-2.3	-2.7
Number of treatments/medications taken	5.9	10.6	16.3	2.6	2.1	-3.9	-3.5	-3.1	3.5	2.7	4.0
Average weekly spirits intake	0.4	0.5	2.4	-1.1	-1.6	-0.5	0.0	0.1	-0.2	-0.3	0.1
Sensitivity / hurt feelings	3.6	6.1	9.4	3.0	1.1	-3.1	-2.3	-1.7	3.1	2.2	2.7
Frequency of depressed mood in last 2 weeks	4.6	6.5	12.6	1.6	0.7	-2.5	-2.7	-2.6	3.1	2.5	3.5
Hearing difficulty/problems: Yes	1.2	1.9	4.7	-1.6	-0.4	0.6	1.3	1.3	-2.2	-1.1	-1.6
Relative age of first facial hair	0.1	0.2	0.5	0.7	0.6	0.7	-0.1	-0.0	-0.1	0.4	-0.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.5	-0.7	-0.7	-0.1	0.3	0.4	-0.3	-0.1	0.3
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.8	0.7	0.9	0.5	0.4	0.5	0.6	-0.9	-0.8
Ever had hysterectomy (womb removed)	1.2	1.4	3.8	0.6	0.4	-0.8	-1.1	-0.9	1.9	0.9	1.8
Systolic blood pressure, automated reading	1.5	4.3	14.6	2.7	3.8	-0.2	-1.7	-2.0	1.8	1.3	0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.5	0.6	0.5	-0.7	-0.4	-0.2	0.6	-0.3	-0.3
Angina	0.3	0.4	0.9	0.9	0.5	0.2	0.4	0.6	0.9	-0.5	0.3
Medication for hormone replacement therapy	0.4	0.4	1.7	0.3	1.3	0.8	-0.4	-0.5	0.6	0.3	-0.2
Vitamin and mineral supplements	2.1	2.8	6.7	0.7	-0.2	1.5	1.8	2.1	-1.0	-2.6	-2.2
Supplements: Zinc	0.3	0.4	1.5	-1.2	-0.9	0.3	0.3	0.1	-0.5	-0.3	-0.3
Medication: Co-codamol	2.6	3.0	7.3	1.7	-0.3	-2.0	-1.3	-1.0	2.1	1.5	2.7
Medication: Metformin	0.5	0.7	3.6	1.9	0.8	-0.7	-0.1	0.4	0.3	-0.7	-0.2
Diabetes (father)	0.5	0.6	1.2	-0.5	0.1	1.1	0.9	0.9	-0.5	-0.8	-1.0
Diabetes (mother)	1.8	2.3	5.1	-1.2	-0.1	2.3	1.1	0.9	-1.9	-1.2	-2.1
Severe depression (siblings)	0.7	0.7	3.7	-1.9	-1.4	-0.0	0.1	0.0	-0.1	0.1	0.1
Pack years adult smoking proportion	0.9	1.4	4.8	-0.4	0.7	2.2	1.0	0.7	-0.9	-1.1	-1.4
Impedance of leg (right)	0.2	0.8	2.2	0.2	0.1	1.4	0.9	0.9	-0.3	-0.9	-1.5
Leg fat-free mass (left)	0.3	1.5	2.7	-1.6	-1.4	-1.0	-0.9	-1.1	0.5	1.4	1.5
Trunk fat percentage	0.0	0.1	0.4	-0.4	-0.3	-0.0	-0.0	-0.1	0.6	0.4	0.6
Hand grip strength (right)	2.7	7.3	10.1	-2.7	-2.2	2.7	2.8	2.4	-3.2	-2.4	-3.0
Townsend deprivation index at recruitment	0.3	0.5	1.1	0.6	1.1	-0.0	-0.8	-0.8	0.4	0.8	0.3
Current tobacco smoking	1.7	2.8	7.0	-2.6	-1.8	1.9	1.4	1.1	-1.8	-1.1	-1.1
Average weekly fortified wine intake	0.6	0.7	1.9	-0.4	1.0	1.4	0.4	0.2	-0.3	-0.9	-1.3
Maternal smoking around birth	0.1	0.1	0.3	0.1	-0.5	-0.5	0.3	0.4	-0.3	-0.2	-0.2
Fed-up feelings	1.1	2.1	5.2	1.1	-0.6	-1.6	-1.2	-1.2	2.3	0.9	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	4.6	6.2	10.0	1.4	0.6	-2.4	-2.7	-2.7	2.9	2.8	3.2
Relative age voice broke	0.4	0.7	1.8	0.2	0.4	1.3	0.8	0.7	-1.0	-0.1	-1.1
Taking other prescription medications	7.2	11.2	17.5	1.6	2.0	-3.9	-3.8	-3.5	3.5	3.3	4.2
Age when periods started (menarche)	0.3	0.7	2.0	0.7	-0.3	0.1	0.7	0.8	-0.2	-1.4	-1.4
Bilateral oophorectomy (both ovaries removed)	4.4	5.1	9.9	1.9	1.2	-2.1	-2.3	-2.0	3.1	2.0	3.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	4.2	2.0	0.2	-0.5	-0.2	0.1	0.3	-0.3	0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.0	0.0	0.1	-0.1	-0.8	-1.0	0.0	1.0	0.1
Qualifications: CSEs or equivalent	1.0	1.3	3.2	1.8	1.6	-0.6	-1.1	-1.1	0.9	0.7	0.4
Serious illness, injury or assault to yourself	0.4	0.5	1.2	-0.0	0.6	-0.3	-0.9	-0.8	1.0	0.5	1.1
High blood pressure	2.5	7.0	12.0	3.5	3.5	-1.6	-2.5	-2.5	3.0	2.0	2.0
Hayfever, allergic rhinitis or eczema	1.1	2.5	7.5	-1.9	-2.7	-0.6	1.3	1.6	-1.8	-0.8	-0.2
Multivitamins +/- minerals	1.0	1.2	3.7	-1.0	-0.1	-0.1	-1.0	-1.3	0.8	1.9	1.4
Stomach or abdominal pain in last month	0.2	0.2	0.5	0.2	0.1	-0.3	-0.6	-0.6	0.7	0.6	0.3
Supplements: Glucosamine	0.3	0.4	1.0	0.4	0.1	-0.8	-0.8	-0.8	0.6	0.3	1.0
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	2.1	-0.2	-0.6	-1.1	-1.0	-0.9	1.4	1.1	1.2
Medication: Atenolol	0.5	0.6	1.8	1.3	0.9	-0.2	-0.5	-0.5	1.1	0.3	0.8
Medication: Levothyroxine sodium	0.3	0.6	2.7	-1.6	-0.4	-0.3	0.8	0.8	-0.2	-0.5	-0.3
Sitting height	0.1	0.9	1.8	-1.4	-1.3	-1.2	-0.7	-0.8	0.1	0.8	0.6
Chronic bronchitis/emphysema (father)	0.2	0.3	0.6	-0.2	0.8	0.6	0.2	0.2	-0.6	-0.5	-0.7
High blood pressure (mother)	0.9	1.3	2.4	-0.6	1.5	0.4	-1.2	-1.5	1.1	1.6	0.8
Body mass index (BMI)	0.1	0.2	0.7	-0.7	-0.8	-0.5	0.1	0.1	-0.1	0.2	0.6
Impedance of leg (left)	0.1	0.6	1.6	0.6	0.4	1.1	0.7	0.8	-0.2	-0.8	-1.3
Leg predicted mass (left)	0.3	1.6	2.6	-1.6	-1.4	-1.0	-1.0	-1.2	0.5	1.5	1.6
Trunk fat mass	0.1	0.3	0.7	-0.8	-0.7	-0.2	-0.2	-0.2	0.6	0.5	0.9
Waist circumference	0.2	0.6	1.9	-0.9	-1.4	-0.8	0.1	0.2	0.3	0.3	1.0
Number of incorrect matches in round	0.8	1.2	2.8	0.8	1.7	-0.6	-1.3	-1.4	0.6	1.3	0.8
Past tobacco smoking	0.1	0.2	0.5	0.6	0.4	0.7	-0.3	-0.5	0.3	0.5	0.2
Alcohol usually taken with meals	0.8	1.2	3.0	-0.6	-1.0	0.5	1.2	0.9	-1.7	-1.1	-1.3
Nervous feelings	2.0	3.6	6.7	1.8	2.6	-1.0	-2.1	-2.1	2.0	1.7	1.5
Frequency of tenseness / restlessness in last 2 weeks	6.3	9.8	18.9	2.6	0.1	-4.4	-3.1	-2.6	3.6	2.7	3.9
Hearing difficulty/problems with background noise	0.2	0.3	0.8	-0.3	-0.8	-0.9	0.4	0.7	-0.2	-0.2	-0.0
Hair/balding pattern: Pattern 2	0.5	0.6	1.8	1.3	0.5	0.2	-0.6	-0.7	1.0	0.7	0.7
Had menopause	1.5	1.9	3.6	0.4	-0.1	0.4	1.5	1.7	-1.6	-1.8	-1.9
Had other major operations	0.4	0.5	1.6	-0.2	1.3	0.1	-0.8	-0.9	0.6	0.3	0.5
Forced vital capacity (FVC)	1.3	5.2	6.3	-2.5	-2.5	2.1	2.3	2.2	-2.0	-1.9	-2.5
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	6.0	2.4	0.4	-1.5	-1.0	-0.7	1.3	0.6	1.8
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	4.7	-0.5	-2.2	-1.2	0.5	1.0	0.6	-0.2	0.8
Qualifications: None of the above	2.3	4.9	13.5	3.7	1.6	-2.3	-1.9	-1.2	2.8	1.1	2.0
Financial difficulties in last 2 years	0.1	0.2	0.9	-0.1	0.0	0.9	0.2	-0.1	-0.4	-0.1	-0.4
Mouth/teeth dental problems	0.7	1.1	3.2	0.0	1.8	0.7	-1.1	-1.5	0.7	1.0	0.2
Heart attack	0.2	0.3	1.4	1.2	0.7	-0.1	-0.1	0.1	0.7	-0.4	0.1
Allergy	0.8	1.8	5.6	1.9	2.4	1.0	-0.7	-1.0	1.4	0.3	-0.3
Pain all over the body in last month	0.4	0.5	1.2	-0.3	-0.4	-1.1	-0.6	-0.5	0.7	0.8	0.8
Diabetes (self-reported)	1.0	1.6	3.5	1.9	1.0	-1.5	-1.2	-0.8	1.6	0.2	1.3
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.9	-0.5	-0.9	-0.4	0.1	0.2	-0.8	0.2	0.1
Medication: Ramipril	1.3	1.7	5.0	2.2	1.2	-1.1	-0.8	-0.4	1.8	0.4	1.2
Medication: Simvastatin	2.5	3.7	10.1	3.2	2.4	-1.5	-1.5	-1.2	2.2	0.8	1.4
Fluid intelligence score	0.3	0.6	3.4	-1.8	-1.2	0.0	0.0	-0.2	0.1	-0.0	-0.2
Illnesses of siblings	0.1	0.2	0.6	-0.5	0.2	0.6	0.1	-0.1	-0.8	0.3	0.2
Neuroticism score	1.2	2.5	3.4	1.5	0.9	-1.8	-1.8	-1.7	1.9	1.4	1.5
Weight	0.2	0.8	2.1	-1.4	-1.2	-0.7	-0.4	-0.6	0.1	0.9	1.1
Impedance of arm (right)	0.2	1.0	1.7	1.3	1.0	-0.2	-0.9	-1.1	1.2	1.2	0.7
Arm fat percentage (right)	0.1	0.3	0.8	0.1	-0.5	-0.7	-0.2	-0.2	0.6	0.5	0.9
Trunk fat-free mass	0.2	1.3	5.3	-2.1	-2.3	-0.1	0.4	0.2	-0.9	-0.1	0.1
Hip circumference	0.5	2.1	5.3	-0.8	-1.2	-1.6	-1.0	-0.9	1.4	1.7	2.3
Time employed in main current job	2.6	3.0	5.5	-2.3	-2.0	1.1	1.5	1.5	-1.9	-1.3	-2.0
Alcohol intake versus 10 years previously	0.5	0.7	2.1	-0.9	0.1	1.1	0.6	0.3	-1.5	-0.0	-1.0
Father’s age at death	1.3	1.8	3.1	0.0	-0.7	1.0	1.5	1.5	-1.8	-1.6	-1.7
Worrier / anxious feelings	1.2	2.3	3.3	1.5	1.2	-1.8	-1.6	-1.4	1.8	1.4	1.2
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	3.3	0.1	-0.4	-1.7	-1.4	-1.4	1.8	1.8	1.8
Falls in the last year	1.1	1.5	5.4	-2.3	-2.2	1.0	0.4	0.1	-0.7	0.4	0.4
Hair/balding pattern: Pattern 3	1.0	1.5	4.0	1.1	2.0	-1.4	-1.3	-1.2	0.9	0.5	0.8
Number of live births	1.5	2.1	8.3	2.9	1.7	-1.3	-0.6	-0.2	1.5	-0.1	0.8
Forced expiratory volume in 1-second (FEV1)	1.3	4.5	7.3	-2.4	-2.7	1.9	2.1	2.0	-1.9	-1.5	-2.2
Pulse rate	4.4	7.5	15.4	-0.9	2.1	-0.9	-3.3	-3.9	1.7	3.9	3.1
Happiness	2.0	2.5	4.5	-0.1	1.3	-1.1	-1.9	-1.9	1.5	2.1	1.7
Noisy workplace	1.4	1.7	2.9	1.0	0.7	-1.7	-1.4	-1.2	1.1	1.5	1.5
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.7	-1.6	0.5	1.1	-0.2	-0.7	-1.1	0.5	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.1	-1.1	-0.2	0.6	0.5	0.2	-0.9	0.2	-0.4
Mouth/teeth dental problems: Dentures	0.7	1.2	3.8	0.5	-0.8	-1.9	-0.8	-0.4	0.8	0.9	1.7
Asthma	0.2	0.3	0.9	-0.9	-0.3	-0.9	-0.5	-0.3	0.1	0.3	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.6	1.6	-0.2	-1.1	-0.1	0.3	0.4	-0.4	0.2
Medication: Cholesterol lowering	3.9	6.1	19.6	4.4	3.1	-2.0	-1.8	-1.2	2.7	0.6	1.8
Depression (self-reported)	4.1	4.9	8.3	0.8	-0.1	-2.2	-2.4	-2.2	2.9	2.7	2.8
Medication: Lansoprazole	0.3	0.3	0.8	0.6	0.2	-0.6	-0.5	-0.4	0.6	0.9	0.7
Prospective memory result	5.7	7.0	9.7	-2.2	-2.4	2.7	3.0	2.8	-3.1	-2.2	-2.5
Lung cancer (father)	0.1	0.1	0.3	-0.3	0.1	0.4	0.1	-0.0	-0.5	-0.2	-0.2
Illnesses of mother	0.5	0.7	1.1	1.1	0.7	-0.9	-0.9	-0.7	0.6	1.0	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.6	7.3	-2.4	-2.7	2.0	2.2	2.1	-2.1	-1.3	-2.0
Pulse wave Arterial Stiffness index	0.7	0.9	2.4	-1.2	0.2	1.0	0.4	0.1	-1.6	-0.7	-1.2
Impedance of arm (left)	0.2	0.9	1.6	0.9	1.1	0.2	-0.8	-1.0	1.2	1.1	0.5
Arm fat mass (right)	0.1	0.3	0.8	-0.8	-0.9	-0.4	-0.0	-0.1	0.2	0.5	0.8
Trunk predicted mass	0.2	1.3	5.0	-2.1	-2.2	-0.0	0.3	0.2	-0.8	-0.0	0.2
Standing height	0.1	1.3	4.5	-2.1	-1.4	-0.1	-0.7	-1.1	0.1	1.2	0.8
Length of working week for main job	0.7	0.8	1.9	0.0	0.3	-1.4	-1.1	-1.0	0.7	1.2	0.7
Exposure to tobacco smoke at home	0.1	0.2	0.6	-0.0	-0.1	0.8	0.4	0.3	0.5	-0.3	-0.2
Breastfed as a baby	1.6	1.9	2.9	1.1	0.3	-1.5	-1.7	-1.7	1.4	1.2	1.7
Tense / ‘highly strung’	1.2	2.0	2.9	1.0	1.5	-1.1	-1.5	-1.7	1.5	1.6	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	8.0	1.9	-0.4	-2.8	-1.7	-1.3	2.0	1.4	2.4
Hair/balding pattern: Pattern 4	0.4	1.0	3.5	0.5	1.9	0.7	-1.1	-1.2	0.8	0.7	0.1
Birth weight of first child	0.2	0.4	1.3	-1.1	-1.0	0.3	0.1	-0.0	0.5	0.5	0.7
Peak expiratory flow (PEF)	0.7	1.7	4.1	-2.0	-1.9	0.9	0.9	0.7	-1.4	-0.6	-1.3
Pulse wave reflection index	4.2	5.2	7.6	-1.4	-2.0	1.7	2.5	2.3	-2.8	-2.7	-2.5
Ever highly irritable/argumentative for 2 days	0.5	0.5	1.3	-0.7	-1.1	-0.7	-0.4	-0.4	-0.1	1.0	0.8
Loud music exposure frequency	1.0	1.1	2.9	-1.5	-0.8	1.2	0.7	0.4	-1.7	-0.5	-0.9
Qualifications: O levels/GCSEs or equivalent	1.0	1.5	8.2	-2.9	-0.6	0.1	-0.6	-1.1	-0.8	1.2	0.1
Mouth/teeth dental problems: Bleeding gums	2.2	2.8	4.1	-1.7	-1.2	1.2	1.7	1.6	-2.0	-1.9	-2.0
Blood clot in the leg (DVT)	0.2	0.3	0.7	-0.5	0.2	-0.0	-0.7	-0.7	0.3	0.6	0.9
Medication: Paracetamol	2.1	3.4	7.8	1.5	2.8	-0.4	-2.0	-2.2	1.7	2.1	1.2
Headache pain in last month	0.1	0.1	0.4	0.3	0.2	0.0	-0.3	-0.3	0.2	0.6	0.2
Medication for cholesterol, blood pressure or diabetes	2.5	4.2	10.6	-3.3	-2.9	1.4	1.8	1.5	-2.1	-0.6	-1.4
Glaucoma (self-reported)	0.2	0.3	0.7	0.0	0.6	0.4	0.4	0.4	-0.8	-0.2	-0.6
Gout (self-reported)	0.0	0.0	0.0	-0.2	0.0	0.0	0.1	0.1	-0.1	0.1	-0.2
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.6	-1.6	-0.8	-0.3	1.2	1.2	-0.8	-0.9	-0.8
Medication: Amlodipine	1.3	1.8	5.8	1.5	2.4	0.1	-1.3	-1.4	1.4	0.8	0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.3	-1.5	-0.9	-0.1	-0.4	-0.3	0.0	0.6	0.4
Birth weight	0.2	0.4	1.0	-0.6	1.0	0.5	-0.7	-0.8	0.0	0.5	0.0
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.0	0.8	0.9	-1.3	-0.9	-0.9	0.6	1.4	0.7
High blood pressure (siblings)	0.4	0.6	1.4	0.0	0.5	-0.7	-0.9	-0.9	1.2	0.7	0.6
Forced vital capacity (FVC), Best measure	1.5	5.4	7.4	-2.4	-2.7	2.0	2.5	2.4	-2.4	-1.8	-2.3
Body fat percentage	0.1	0.2	0.6	-0.3	-0.4	-0.3	-0.1	-0.2	0.6	0.4	0.8
Leg fat percentage (right)	0.1	0.3	0.8	0.2	-0.5	-0.7	-0.2	-0.1	0.8	0.3	0.9
Arm fat-free mass (right)	0.3	1.4	6.3	-2.5	-2.1	0.1	0.3	0.0	-0.6	0.1	0.3
Exposure to tobacco smoke outside home	3.7	4.9	6.6	2.4	1.8	-2.0	-2.5	-2.6	1.9	2.1	2.3
Comparative body size at age 10	0.3	0.8	1.6	-1.3	0.1	1.1	0.8	0.6	-1.2	-0.9	-0.8
Number of full brothers	0.2	0.2	0.4	-0.6	0.0	0.5	-0.3	-0.6	0.6	0.6	0.2
Worry too long after embarrassment	0.1	0.2	0.7	-0.0	-0.6	-0.8	0.1	0.2	0.0	0.3	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.3	0.3	0.4	-1.4	-1.5	-1.4	0.7	1.4	1.2
Wheeze or whistling in the chest in last year	0.8	1.4	2.9	0.4	0.7	-1.4	-1.5	-1.4	0.6	1.7	1.1
Number of children fathered	1.0	1.2	2.1	0.5	-0.4	0.7	1.2	1.2	-1.4	-1.3	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.5	0.6	1.6	0.6	-0.9	-1.1	0.5	0.8	0.3
Age at first live birth	2.8	4.9	11.1	-3.3	-2.0	2.3	1.8	1.4	-2.5	-1.9	-1.8
Pulse wave peak to peak time	0.5	0.6	1.8	0.8	-0.4	-0.7	-0.3	-0.0	1.3	0.7	1.1
Health satisfaction	0.4	0.5	1.0	0.2	0.8	-0.6	-0.7	-0.5	0.6	1.0	1.0
Shortness of breath walking on level ground	0.3	0.4	1.4	-1.2	-0.3	0.2	0.4	0.4	-0.8	-0.1	-0.6
Qualifications: College or University degree	0.4	1.2	4.8	-2.2	-0.7	1.0	0.6	0.1	-1.6	0.1	-0.4
Eye problems/disorders: None of the above	0.1	0.2	0.4	-0.6	-0.0	0.1	-0.3	-0.6	-0.2	0.6	0.1
Mouth/teeth dental problems: Loose teeth	1.7	2.0	6.1	0.4	-1.0	0.2	1.6	2.1	-0.9	-2.5	-1.1
Emphysema/chronic bronchitis	0.1	0.1	0.3	-0.6	-0.6	0.4	0.2	0.3	-0.2	-0.2	-0.0
Medication for pain relief, constipation, heartburn	3.0	5.1	6.3	-2.5	-2.5	2.0	2.5	2.2	-2.1	-2.0	-2.3
Neck or shoulder pain in last month	0.1	0.1	0.7	0.1	-0.9	-0.4	-0.3	-0.2	0.1	0.2	0.2
Medication: Blood pressure	1.2	2.1	4.8	2.1	2.2	-0.9	-1.3	-1.2	1.8	0.2	0.7
Angina (self-reported)	0.4	0.5	1.1	0.8	0.2	0.4	0.7	1.0	0.7	-1.0	-0.0
Migraine (self-reported)	0.5	0.6	1.5	1.1	0.5	-0.8	-0.4	-0.2	1.2	-0.0	1.0
Medication: Ibuprofen	0.4	0.5	1.8	1.3	-0.7	-0.7	0.2	0.5	0.3	-0.7	-0.1
Medication: Allopurinol	0.3	0.4	0.8	0.5	0.2	-0.9	-0.6	-0.5	0.7	0.6	0.9
Medication: Omeprazole	3.5	4.2	5.7	1.8	2.2	-2.0	-2.2	-2.1	2.4	1.8	1.8
Medication: Seretide 50 evohaler	1.6	1.8	3.0	-0.2	-0.5	-1.6	-1.7	-1.6	1.4	1.3	1.7
Mean time to correctly identify matches	0.9	1.7	7.4	0.2	0.0	-2.7	-1.3	-0.9	0.8	0.5	1.7
Heart disease (mother)	1.1	1.3	3.6	-1.1	0.1	1.9	1.2	0.7	-1.1	-1.0	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	3.9	1.1	1.6	-0.5	-1.8	-2.0	1.1	1.2	1.2
Whole body fat mass	0.1	0.4	0.8	-0.9	-0.8	-0.3	-0.2	-0.3	0.5	0.5	0.9
Leg fat mass (right)	0.2	0.9	2.5	-0.2	-0.5	-1.1	-0.8	-0.8	1.0	1.0	1.6
Arm predicted mass (right)	0.2	1.1	5.2	-2.3	-1.9	0.0	0.2	0.1	-0.5	0.0	0.3
Pulse rate, automated reading	9.6	31.0	54.8	2.3	6.2	-2.7	-6.6	-7.4	3.9	7.1	5.7
Alcohol intake frequency.	0.0	0.1	0.4	0.1	0.3	0.6	-0.0	-0.1	-0.5	0.0	-0.3
Comparative height size at age 10	0.3	1.9	6.1	-2.5	-1.5	-0.8	-0.9	-1.2	0.0	1.4	1.4
Number of full sisters	3.3	4.0	6.8	1.6	1.0	-1.3	-2.3	-2.4	2.6	2.2	1.9
Suffer from ‘nerves’	0.1	0.2	0.3	-0.4	-0.3	0.4	0.5	0.6	-0.3	-0.4	-0.5
Overall health rating	1.4	3.1	4.9	0.5	1.1	-1.5	-2.1	-2.2	1.9	1.9	2.0
Chest pain or discomfort	1.5	2.2	3.6	0.7	1.1	-1.3	-1.7	-1.5	1.9	1.8	1.5
Had major operations	0.3	0.4	1.0	0.8	0.3	-0.3	0.4	0.5	-0.7	-1.0	-0.4
Age at last live birth	0.6	0.8	2.1	-1.0	-0.2	1.4	0.7	0.5	-1.3	-0.8	-0.8
Family relationship satisfaction	3.8	4.7	6.4	0.8	2.0	-1.4	-2.5	-2.5	2.3	2.5	2.5
Leg pain on walking	1.0	1.3	2.4	-0.1	-1.4	1.0	1.5	1.6	-1.2	-0.9	-0.7
Qualifications: NVQ or HND or HNC or equivalent	2.6	3.1	5.9	0.6	1.4	-0.9	-2.0	-2.2	1.7	2.4	2.0
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.4	-0.1	-1.8	-1.0	0.2	0.6	0.8	-0.7	0.6
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.0	0.6	0.9	-0.9	-0.7	-0.6	1.0	0.8	0.6
Medication: Aspirin	0.9	1.2	2.8	1.2	1.1	-0.6	-1.0	-0.7	1.2	0.6	1.7
Supplements: Vitamin C	0.3	0.3	1.1	-0.8	-1.1	-0.3	0.1	-0.2	-0.6	0.5	0.4
Knee pain experienced in last month	0.7	1.1	2.4	0.6	0.3	-0.4	-1.1	-1.4	1.1	1.1	1.5
Hypertension (Self-reported)	3.1	8.6	14.8	3.8	3.8	-1.7	-2.8	-2.8	3.3	2.2	2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.6	3.0	5.7	0.5	1.4	-1.7	-2.0	-2.0	1.5	2.4	1.7
Illnesses of father: Heart disease	0.9	1.3	4.2	-0.8	-2.0	0.4	1.2	1.3	-0.5	-1.4	-0.3
Illnesses of siblings: Diabetes	0.6	0.8	2.0	0.2	-1.1	-0.3	1.0	1.4	-0.6	-0.7	-1.0
Smoking status: Previous	0.2	0.3	1.5	0.6	0.4	-1.2	-0.2	0.2	0.6	-0.5	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.4	-1.5	-1.4	-0.4	-0.4	-0.5	0.2	1.1	0.6
Whole body fat-free mass	0.2	1.3	4.8	-2.2	-2.1	-0.4	-0.1	-0.3	-0.4	0.5	0.7
Leg fat-free mass (right)	0.3	1.8	3.1	-1.6	-1.3	-1.2	-1.1	-1.3	0.5	1.6	1.7
Arm fat percentage (left)	0.1	0.3	0.7	-0.2	-0.5	-0.5	-0.2	-0.2	0.7	0.5	0.8
Average weekly red wine intake	0.5	0.8	2.0	-0.1	-0.9	-0.5	0.9	1.2	-0.5	-1.4	-0.7
Handedness (chirality/laterality): Left-handed	5.7	6.9	9.4	2.4	2.4	-1.7	-3.0	-3.0	3.1	2.4	2.7
Mood swings	0.5	1.0	1.6	1.2	0.0	-1.2	-0.8	-0.7	1.3	0.9	1.3
Loneliness, isolation	0.8	1.1	3.0	-0.2	1.1	0.1	-1.4	-1.7	0.5	1.4	0.7
Long-standing illness, disability or infirmity	1.4	2.2	4.5	-0.6	0.4	-2.1	-1.6	-1.5	1.1	1.8	1.8
Ever had bowel cancer screening	0.6	0.8	1.7	-0.6	1.0	-0.6	-1.0	-1.3	0.0	1.0	0.7
Diabetes diagnosed by doctor	1.0	1.6	4.0	2.0	1.2	-1.4	-1.2	-0.8	1.4	0.5	1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.0	-1.0	0.0	0.9	0.1	-0.2	-0.4	-0.0	0.0
Friendships satisfaction	0.6	0.8	1.1	-0.0	1.1	-0.3	-1.0	-1.0	1.0	1.0	0.9
Qualifications: nursing, teaching	0.9	1.5	4.2	-2.1	-0.6	1.4	0.9	0.5	-1.6	-0.3	-1.2
Commuting to job workplace: Walk	0.6	0.6	3.1	-0.5	0.6	1.8	0.4	0.1	-0.7	-0.1	-0.6
Eye problems/disorders: Cataract	1.7	2.0	3.8	-0.1	-0.9	1.2	1.9	1.9	-1.0	-1.9	-1.4
Mouth/teeth dental problems: Mouth ulcers	1.2	2.0	3.6	0.3	-0.4	1.2	1.8	1.9	-1.3	-1.5	-1.8
Medication for cholesterol	3.3	5.0	6.5	-2.0	-2.5	1.3	2.5	2.5	-2.5	-2.4	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.8	1.4	-0.4	1.1	-0.4	-0.9	-1.1	0.4	0.9	1.2
Back pain experienced in last month	0.4	0.5	2.4	0.3	-1.6	-0.7	0.1	0.3	0.9	0.2	0.4
Mineral and other dietary supplements	0.7	0.9	2.0	-0.0	0.6	1.4	0.9	0.9	-0.2	-1.1	-1.3
Breast cancer (self-reported)	0.2	0.3	1.4	-0.1	1.2	0.8	-0.1	-0.2	-0.1	0.0	-0.5
Asthma (self-reported)	0.2	0.3	0.9	-0.9	-0.6	-1.0	-0.3	-0.1	0.1	0.2	0.4
Osteoporosis (self-reported)	1.6	2.0	3.8	-0.1	1.2	-2.0	-1.5	-1.4	0.9	1.9	1.5
Osteoarthritis (self-reported)	2.6	3.4	6.6	1.4	1.4	-1.1	-2.0	-2.1	1.4	2.1	2.6
Medication: Aspirin	0.8	1.1	2.4	1.5	1.0	-0.6	-0.8	-0.4	1.3	0.3	1.5
Medication: Gliclazide	1.6	1.8	3.6	0.1	-0.8	1.3	1.5	1.5	-1.2	-1.9	-1.5
Illnesses of father: None of the above (group 1)	1.2	1.4	3.4	0.3	1.7	-0.1	-1.2	-1.4	0.9	1.9	0.9
Smoking status: Current	2.0	3.1	7.0	-2.6	-1.8	1.9	1.5	1.1	-2.1	-1.1	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.7	6.4	-0.5	-1.5	2.5	2.4	2.2	-1.2	-2.0	-2.1
Whole body water mass	0.2	1.2	4.5	-2.1	-2.1	-0.5	-0.0	-0.2	-0.5	0.4	0.6
Leg predicted mass (right)	0.3	1.6	2.7	-1.6	-1.3	-1.1	-1.0	-1.2	0.5	1.5	1.6
Arm fat mass (left)	0.1	0.3	1.0	-1.0	-1.0	-0.2	0.1	0.0	0.1	0.3	0.6
Number of self-reported non-cancer illnesses	5.5	9.5	15.3	1.8	1.5	-3.9	-3.4	-3.1	2.9	3.5	3.7
Average weekly champagne plus white wine intake	1.5	2.0	3.8	-0.2	-0.8	1.0	2.0	1.9	-1.5	-1.4	-1.7
Miserableness	0.7	1.2	2.8	0.9	-1.2	-1.7	-0.5	-0.1	1.6	0.4	1.2
Guilty feelings	0.1	0.1	0.4	-0.3	0.3	-0.1	-0.4	-0.6	-0.5	0.3	0.1
Wears glasses or contact lenses	0.6	0.7	3.0	-0.8	-0.9	-1.7	-0.3	-0.1	0.2	0.6	0.8
Ever taken oral contraceptive pill	0.6	0.7	2.7	-1.6	-1.4	-0.2	0.3	0.3	-0.6	-0.4	0.1
Hearing aid user	1.3	1.5	4.0	-2.0	-1.8	0.7	0.9	0.9	-1.4	-0.6	-0.3
Mother’s age at death	2.7	3.4	8.9	-0.7	0.1	3.0	1.9	1.7	-1.3	-1.8	-2.5
Financial situation satisfaction	0.6	0.8	3.4	-1.8	-0.9	1.1	0.5	0.2	-0.8	0.2	-0.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.4	-0.3	-0.9	-1.1	-0.4	-0.1	0.9	0.5	1.2
Commuting to job workplace: Public transport	0.4	0.5	1.2	-1.1	-0.1	1.0	0.3	-0.1	-0.9	0.4	-0.6
Eye problems/disorders: Glaucoma	0.6	0.7	1.9	0.8	1.4	-0.4	-0.9	-0.8	0.6	0.9	0.4
Medication: Blood pressure	3.3	6.4	11.8	2.3	3.4	-1.7	-2.7	-2.8	2.1	2.6	2.2
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.2	-0.9	-0.7	-0.4	-0.6	-0.8	-0.0	0.9	1.1
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.8	-0.5	-0.9	-0.3	-0.0	-0.1	-0.4	0.0	0.3
High cholesterol (Self-reported)	1.6	2.8	11.3	3.4	2.2	-0.9	-1.0	-0.8	1.7	0.2	1.0
Medication: Bendroflumethiazide	5.6	8.5	11.3	2.3	3.2	-1.8	-3.2	-3.4	2.7	3.3	3.2
Medication: Paracetamol	2.2	3.4	6.1	0.6	2.2	-0.6	-2.2	-2.5	1.8	2.2	1.7
Medication: Lisinopril	1.1	1.4	3.0	1.7	0.8	-0.7	-1.1	-1.1	1.6	0.7	1.4
Medication: Atorvastatin	0.4	0.4	1.8	1.3	0.9	-0.4	-0.3	-0.0	0.6	-0.4	0.5
Illnesses of father: High blood pressure	1.3	1.6	3.7	0.1	-0.1	1.3	1.1	1.1	-1.3	-1.9	-1.8
Alcohol drinker status: Never	0.3	0.3	1.5	0.3	0.4	1.2	0.3	0.4	-0.3	-0.5	-0.5
Ever smoked	0.2	0.3	1.1	-1.0	-0.6	-0.2	0.6	0.6	-0.6	-0.4	-0.2
Basal metabolic rate	0.2	1.1	4.0	-2.0	-1.9	-0.5	-0.2	-0.4	-0.3	0.7	0.8
Leg fat percentage (left)	0.1	0.4	1.0	0.4	-0.3	-0.8	-0.2	-0.1	0.9	0.3	1.0
Arm fat-free mass (left)	0.2	1.2	4.8	-2.2	-2.0	-0.3	0.2	0.0	-0.8	0.3	0.5
Number of operations (self-reported)	0.2	0.3	0.6	0.8	0.4	-0.6	-0.2	-0.1	0.7	-0.3	0.6
Average weekly beer plus cider intake	0.1	0.1	0.3	0.2	0.5	0.1	-0.3	-0.1	0.5	0.2	-0.1
Irritability	0.7	1.2	1.6	1.1	1.1	-1.1	-1.3	-1.2	1.1	1.1	0.8
Risk taking	1.6	2.3	2.9	-1.6	-1.7	1.4	1.6	1.7	-1.2	-1.5	-1.3
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.7	-0.7	-0.8	-0.4	0.2	0.0	-1.3	-0.0	-0.1
Fractured/broken bones in last 5 years	1.2	1.6	2.7	-0.1	-1.3	-0.2	1.3	1.6	-1.5	-1.5	-1.5
Age started oral contraceptive pill	2.7	3.3	5.3	-0.8	-1.1	2.2	2.2	2.0	-1.2	-2.3	-2.0
Diastolic blood pressure, automated reading	3.6	11.3	27.1	2.6	5.2	-0.3	-3.7	-4.3	2.6	3.5	2.3
Ever depressed for a whole week	0.6	0.7	2.7	-1.1	-1.6	-0.9	0.3	0.5	-0.8	-0.2	0.1
Unable to work because of sickness or disability	2.7	3.5	6.0	-0.1	1.0	-2.0	-2.5	-2.4	1.3	2.0	2.2
Commuting to job workplace: Cycle	1.9	2.2	5.9	-1.3	-1.2	1.0	1.4	1.1	-2.4	-1.0	-1.9
Myopia	0.5	0.7	1.8	-0.5	0.7	0.9	0.5	0.3	-1.1	-0.6	-1.3
Vascular/heart problems diagnosed by doctor	2.5	6.9	12.6	-3.5	-3.5	1.6	2.4	2.4	-2.9	-1.8	-2.0
Cholesterol lowering medication	0.7	1.1	2.9	1.7	0.6	-1.1	-0.8	-0.5	1.3	0.7	1.1
Medication: Omeprazole (e.g. Zanprol)	3.5	4.2	6.1	1.3	2.5	-1.7	-2.3	-2.4	2.0	2.2	1.9
Pain experienced in last month	1.2	2.0	3.8	-1.5	0.5	2.0	1.3	1.0	-1.9	-1.0	-1.6
Supplements: Calcium	1.6	1.7	6.2	-2.5	-2.4	-0.0	0.7	0.5	-1.1	-0.1	-0.5
Basal cell carcinoma (self-reported)	1.3	1.6	8.3	0.6	2.9	1.7	-0.1	-0.5	-0.2	-0.2	-0.7
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.5	1.6	0.9	-0.5	-0.4	-0.1	1.0	-0.2	0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.6	-0.6	0.3	0.1	-0.6	-0.6	0.3	0.6	0.7
Heart disease (siblings)	0.5	0.6	1.8	1.1	-0.3	-1.0	-0.2	0.3	1.4	-0.2	0.7
Alcohol drinker status: Previous	1.1	1.3	2.3	-0.2	-0.0	-1.5	-1.3	-1.2	1.1	1.3	1.4
Pack years of smoking	1.4	2.1	5.7	-0.3	0.7	2.4	1.4	1.2	-1.1	-1.7	-1.7
Impedance of whole body	0.1	0.3	0.7	0.7	0.8	0.8	-0.1	-0.2	0.6	0.2	-0.5
Leg fat mass (left)	0.2	0.8	2.3	-0.2	-0.6	-1.1	-0.7	-0.7	0.9	0.9	1.5
Arm predicted mass (left)	0.3	1.4	5.3	-2.3	-2.2	-0.3	0.3	0.1	-0.8	0.1	0.5