[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr7:73,017,005-75,842,792

Best TWAS P=4.81e-11 · Best GWAS P=8.41e-08 conditioned to 0.331

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
29	METSIM	Adipose	NCF1	0.05	0.03	blup	130	0.04	3.9e-07	4.0	6.6	4.8e-11	-0.19	0.03	0.78	TRUE
11	GTEx	Cells EBV-transformed lymphocytes	STAG3L1	0.43	0.21	enet	21	0.23	3.8e-08	-5.2	-5.5	4.7e-08	0.84	0.00	1.00	TRUE
23	GTEx	Ovary	CLIP2	0.24	-0.01	enet	35	0.00	3.7e-01	4.1	5.6	1.7e-08	0.00	0.00	0.05	FALSE
37	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PMS2L3	0.23	0.14	lasso	2	0.14	1.3e-04	-5.2	-5.4	7.9e-08	0.94	0.00	0.85	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	POM121C	0.36	0.26	lasso	7	0.27	2.8e-34	-5.2	-5.4	8.3e-08	0.95	0.00	1.00	FALSE
2	GTEx	Adipose Subcutaneous	PMS2P3	0.15	0.12	lasso	3	0.10	9.8e-09	-5.4	-5.4	8.5e-08	0.99	0.00	1.00	FALSE
12	GTEx	Cells Transformed fibroblasts	PMS2P3	0.23	0.15	lasso	6	0.15	1.4e-11	-5.4	-5.4	8.5e-08	0.97	0.00	1.00	FALSE
26	GTEx	Stomach	PMS2P3	0.16	0.07	lasso	5	0.09	3.7e-05	-5.0	-5.4	8.5e-08	0.94	0.00	0.99	FALSE
28	GTEx	Whole Blood	STAG3L1	0.08	0.06	lasso	3	0.07	2.8e-07	-5.2	-5.4	8.7e-08	0.96	0.00	1.00	FALSE
16	GTEx	Esophagus Mucosa	PMS2P3	0.14	0.15	lasso	2	0.14	9.7e-10	-5.2	-5.3	9.5e-08	0.96	0.00	1.00	FALSE
19	GTEx	Esophagus Muscularis	TRIM73	0.12	0.07	lasso	2	0.05	3.5e-04	-5.4	-5.3	9.5e-08	1.00	0.00	0.99	FALSE
21	GTEx	Muscle Skeletal	PMS2P3	0.07	0.07	lasso	2	0.06	3.8e-06	-5.2	-5.3	1.0e-07	0.96	0.00	1.00	FALSE
22	GTEx	Nerve Tibial	PMS2P3	0.29	0.13	enet	4	0.18	1.1e-12	-5.0	-5.3	1.1e-07	0.90	0.00	1.00	FALSE
25	GTEx	Skin Sun Exposed Lower leg	PMS2P3	0.38	0.30	lasso	3	0.29	1.9e-24	-5.2	-5.3	1.1e-07	0.96	0.00	1.00	FALSE
3	GTEx	Adipose Subcutaneous	STAG3L1	0.30	0.24	enet	24	0.27	2.4e-22	-5.2	-5.3	1.2e-07	0.90	0.00	1.00	FALSE
13	GTEx	Cells Transformed fibroblasts	STAG3L1	0.22	0.17	lasso	4	0.18	2.6e-13	-5.2	-5.3	1.2e-07	0.94	0.00	1.00	FALSE
4	GTEx	Adipose Visceral Omentum	STAG3L1	0.20	0.19	lasso	3	0.17	2.3e-09	-5.2	-5.3	1.3e-07	0.96	0.00	1.00	FALSE
5	GTEx	Artery Coronary	STAG3L1	0.28	0.13	lasso	4	0.17	1.8e-06	-5.0	-5.3	1.4e-07	0.86	0.01	0.99	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	STAG3L1	0.46	0.32	lasso	4	0.32	2.2e-42	-5.2	-5.3	1.4e-07	0.96	0.00	1.00	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	POM121C	0.04	0.04	lasso	2	0.03	1.2e-07	-5.2	-5.3	1.4e-07	0.96	0.00	1.00	FALSE
6	GTEx	Artery Tibial	POM121C	0.12	0.10	lasso	1	0.10	6.8e-08	-5.2	-5.2	1.5e-07	0.96	0.00	1.00	FALSE
10	GTEx	Breast Mammary Tissue (Female)	STAG3L1	0.04	0.12	lasso	1	0.04	2.9e-02	-5.2	-5.2	1.5e-07	0.96	0.00	0.88	FALSE
15	GTEx	Colon Transverse	STAG3L1	0.22	0.18	lasso	1	0.16	4.0e-08	-5.2	-5.2	1.5e-07	0.96	0.00	1.00	FALSE
17	GTEx	Esophagus Mucosa	POM121C	0.13	0.10	lasso	1	0.07	1.0e-05	-5.2	-5.2	1.5e-07	0.96	0.00	0.99	FALSE
18	GTEx	Esophagus Mucosa	STAG3L1	0.19	0.19	lasso	1	0.18	2.4e-12	-5.2	-5.2	1.5e-07	0.96	0.00	1.00	FALSE
20	GTEx	Heart Left Ventricle	POM121C	0.13	0.12	lasso	1	0.09	2.2e-05	-5.2	-5.2	1.5e-07	0.96	0.00	0.99	FALSE
24	GTEx	Skin Not Sun Exposed Suprapubic	STAG3L1	0.13	0.19	lasso	1	0.18	2.6e-10	-5.2	-5.2	1.5e-07	0.96	0.00	1.00	FALSE
30	METSIM	Adipose	POM121C	0.11	0.08	lasso	1	0.08	1.6e-11	-5.2	-5.2	1.5e-07	0.96	0.00	1.00	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	PMS2P3	0.05	0.04	lasso	1	0.03	4.6e-05	-5.2	-5.2	1.5e-07	0.96	0.00	1.00	FALSE
7	GTEx	Artery Tibial	STAG3L1	0.25	0.19	lasso	4	0.19	8.3e-15	-5.2	-5.2	1.6e-07	0.96	0.00	1.00	FALSE
35	ROSMAP	Brain Pre-frontal Cortex	GTF2IP1	0.09	0.06	lasso	3	0.05	1.7e-07	-5.2	-5.2	1.8e-07	0.96	0.00	1.00	FALSE
9	GTEx	Breast Mammary Tissue	STAG3L1	0.16	0.15	lasso	2	0.14	8.7e-08	-5.2	-5.2	2.0e-07	0.94	0.00	1.00	FALSE
8	GTEx	Brain Cerebellar Hemisphere	POM121C	0.33	0.32	lasso	3	0.30	1.4e-08	-5.2	-5.2	2.4e-07	0.96	0.00	0.99	FALSE
27	GTEx	Testis	TRIM73	0.20	0.21	lasso	2	0.19	6.2e-09	-5.2	-5.2	2.4e-07	0.96	0.00	1.00	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	PMS2P2	0.17	0.08	enet	8	0.08	6.0e-10	-5.2	-5.2	2.5e-07	0.95	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	POM121C	0.08	0.05	lasso	2	0.04	1.1e-05	-5.2	-5.2	2.6e-07	0.95	0.00	0.99	FALSE
14	GTEx	Colon Sigmoid	STAG3L1	0.30	0.18	lasso	4	0.18	8.5e-07	-5.2	-5.1	3.0e-07	0.94	0.00	0.99	FALSE