[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr7:89,096,541-90,699,073

Best TWAS P=4.93e-11 · Best GWAS P=1.9e-10 conditioned to 0.481

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	STEAP1	0.13	0.12	enet	26	0.12	6.3e-15	6.2	5.5	3.7e-08	0.89	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	STEAP2	0.11	0.06	lasso	5	0.07	1.1e-06	6.1	-5.4	5.6e-08	-0.93	0.02	0.98	FALSE
3	GTEx	Artery Tibial	C7orf63	0.07	0.01	enet	11	0.03	1.4e-03	5.5	-5.2	2.0e-07	-0.76	0.16	0.76	FALSE
4	GTEx	Artery Tibial	GTPBP10	0.18	0.02	enet	18	0.11	9.0e-09	5.1	-5.4	8.2e-08	-0.70	0.12	0.87	FALSE
5	GTEx	Artery Tibial	STEAP2	0.22	0.24	enet	21	0.25	2.9e-19	5.5	-5.5	5.0e-08	-0.91	0.13	0.87	FALSE
6	GTEx	Brain Frontal Cortex BA9	GTPBP10	0.15	0.15	lasso	8	0.10	1.1e-03	6.1	-5.7	1.2e-08	-0.95	0.05	0.86	FALSE
7	GTEx	Breast Mammary Tissue	GTPBP10	0.13	0.04	lasso	4	0.04	3.6e-03	4.7	-5.6	1.9e-08	-0.95	0.03	0.95	FALSE
8	GTEx	Cells Transformed fibroblasts	STEAP2	0.19	0.16	enet	14	0.17	1.5e-12	6.1	-5.7	1.4e-08	-0.98	0.02	0.98	FALSE
9	GTEx	Esophagus Mucosa	C7orf63	0.11	0.01	lasso	5	0.00	5.9e-01	6.3	5.8	5.7e-09	0.95	0.02	0.95	FALSE
10	GTEx	Esophagus Mucosa	STEAP1	0.30	0.42	enet	14	0.40	9.7e-29	6.2	6.3	2.6e-10	0.99	0.01	0.99	FALSE
11	GTEx	Esophagus Muscularis	STEAP2	0.10	0.06	enet	16	0.07	3.4e-05	5.8	-5.7	1.5e-08	-0.94	0.02	0.98	FALSE
12	GTEx	Muscle Skeletal	GTPBP10	0.07	0.03	lasso	4	0.04	9.4e-05	6.3	-5.2	1.7e-07	-0.94	0.01	0.99	FALSE
13	GTEx	Pituitary	GTPBP10	0.22	0.01	enet	8	0.01	1.6e-01	6.4	-6.4	1.4e-10	-0.91	0.03	0.76	FALSE
14	GTEx	Prostate	GTPBP10	0.20	0.00	lasso	6	0.00	2.4e-01	4.2	-5.6	2.1e-08	-0.81	0.08	0.57	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	STEAP2	0.12	0.12	lasso	4	0.13	9.5e-08	6.2	-5.9	2.7e-09	-0.98	0.02	0.98	FALSE
16	METSIM	Adipose	STEAP2	0.07	0.05	lasso	6	0.06	8.5e-10	6.1	-5.3	1.4e-07	-0.91	0.03	0.97	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	STEAP2	0.10	0.10	lasso	4	0.10	9.5e-13	6.1	-6.0	1.8e-09	-0.94	0.03	0.97	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	STEAP1	0.01	0.00	blup	40	0.01	1.1e-02	6.2	6.3	2.6e-10	0.91	0.01	0.94	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STEAP1	0.05	0.05	enet	6	0.06	1.5e-07	6.2	6.1	1.3e-09	0.92	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	STEAP1	0.14	0.03	enet	7	0.06	6.0e-04	6.1	-5.7	1.2e-08	-0.82	0.01	0.89	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	STEAP1	0.03	0.04	lasso	2	0.03	5.6e-05	-6.3	6.4	2.1e-10	0.95	0.01	0.97	FALSE
22	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	STEAP1	0.04	0.03	blup	40	0.03	1.8e-04	6.2	6.6	4.9e-11	0.93	0.01	0.98	TRUE
23	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	STEAP1	0.06	0.04	blup	40	0.05	3.7e-04	6.3	6.5	8.9e-11	0.99	0.01	0.98	FALSE
24	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	STEAP1	0.09	0.02	lasso	7	0.01	1.3e-01	6.2	6.4	1.9e-10	0.92	0.01	0.90	FALSE
25	The Cancer Genome Atlas	Soft Tissue Sarcoma	GTPBP10	0.06	0.05	enet	4	0.05	1.1e-03	5.6	-5.3	1.3e-07	-0.89	0.00	0.97	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	STEAP1	0.02	0.01	blup	40	0.01	1.8e-02	5.0	6.0	1.6e-09	0.80	0.04	0.58	FALSE