TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr8:22,687,572-24,094,711
Best TWAS P=4.01e-08 · Best GWAS P=8.01e-08 conditioned to 0.216
22.8M
23M
23.2M
23.4M
23.6M
23.8M
24M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
SLC25A37
0.13
0.05
lasso
5
0.04
3.0e-04
4.3
-5.5
4.0e-08
-0.86
0.02
0.98
TRUE
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
SLC25A37
0.11
0.09
lasso
5
0.09
7.8e-10
5.4
5.4
7.2e-08
0.72
0.00
1.00
FALSE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SLC25A37
0.13
0.00
blup
123
0.03
9.4e-03
4.9
5.1
2.6e-07
0.67
0.01
0.75
FALSE