Best TWAS P=4.01e-08 · Best GWAS P=8.01e-08 conditioned to 0.216
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | SLC25A37 | 0.13 | 0.05 | lasso | 5 | 0.04 | 3.0e-04 | 4.3 | -5.5 | 4.0e-08 | -0.86 | 0.02 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SLC25A37 | 0.11 | 0.09 | lasso | 5 | 0.09 | 7.8e-10 | 5.4 | 5.4 | 7.2e-08 | 0.72 | 0.00 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC25A37 | 0.13 | 0.00 | blup | 123 | 0.03 | 9.4e-03 | 4.9 | 5.1 | 2.6e-07 | 0.67 | 0.01 | 0.75 | FALSE |