Best TWAS P=2.62e-17 · Best GWAS P=6.98e-22 conditioned to 8.28e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | CASP7 | 0.10 | -0.01 | enet | 15 | 0.04 | 4.3e-02 | 3.1 | -5.6 | 2.8e-08 | 0.00 | 0.06 | 0.05 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ADRB1 | 0.16 | 0.03 | enet | 31 | 0.07 | 4.1e-08 | -8.6 | 8.5 | 2.6e-17 | -0.40 | 0.05 | 0.65 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | C10orf118 | 0.03 | 0.01 | blup | 42 | 0.02 | 1.9e-03 | -4.1 | 6.3 | 2.7e-10 | -0.17 | 0.01 | 0.31 | TRUE |