TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Diastolic blood pressure, automated reading
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chr10:114,740,745-116,183,647
Best TWAS P=2.62e-17 · Best GWAS P=6.98e-22 conditioned to 8.28e-09
114.8M
115M
115.2M
115.4M
115.6M
115.8M
116M
116.2M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ADRB1
0.16
0.03
enet
31
0.07
4.1e-08
-8.6
8.5
2.6e-17
-0.40
0.05
0.65
TRUE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
C10orf118
0.03
0.01
blup
42
0.02
1.9e-03
-4.1
6.3
2.7e-10
-0.17
0.01
0.31
TRUE
1
GTEx
Breast Mammary Tissue (Male)
CASP7
0.10
-0.01
enet
15
0.04
4.3e-02
3.1
-5.6
2.8e-08
0.00
0.06
0.05
TRUE