Best TWAS P=5.11e-12 · Best GWAS P=2.42e-11 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | TNNT3 | 0.33 | 0.16 | lasso | 7 | 0.17 | 2.0e-09 | 5.3 | 5.6 | 2.2e-08 | -0.48 | 0.22 | 0.78 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | LSP1 | 0.12 | 0.08 | lasso | 5 | 0.10 | 5.0e-11 | -6.7 | -6.8 | 1.3e-11 | 0.92 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LSP1 | 0.07 | 0.03 | lasso | 4 | 0.03 | 2.4e-04 | 5.7 | -6.9 | 5.1e-12 | 0.76 | 0.01 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TNNI2 | 0.11 | 0.09 | lasso | 2 | 0.08 | 4.1e-06 | 5.7 | -5.7 | 1.2e-08 | 0.50 | 0.24 | 0.63 | TRUE |