TWAS
hub
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
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Diastolic blood pressure, automated reading
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chr11:1,242,690-2,640,824
Best TWAS P=5.11e-12 · Best GWAS P=2.42e-11 conditioned to NaN
1.2M
1.4M
1.6M
1.8M
2M
2.2M
2.4M
2.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
LSP1
0.07
0.03
lasso
4
0.03
2.4e-04
5.7
-6.9
5.1e-12
0.76
0.01
0.90
TRUE
4
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
TNNI2
0.11
0.09
lasso
2
0.08
4.1e-06
5.7
-5.7
1.2e-08
0.50
0.24
0.63
TRUE
1
GTEx
Skin Not Sun Exposed Suprapubic
TNNT3
0.33
0.16
lasso
7
0.17
2.0e-09
5.3
5.6
2.2e-08
-0.48
0.22
0.78
TRUE
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
LSP1
0.12
0.08
lasso
5
0.10
5.0e-11
-6.7
-6.8
1.3e-11
0.92
0.00
1.00
FALSE