Best TWAS P=1.09e-12 · Best GWAS P=5.5e-15 conditioned to 0.022
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | -4.8 | 7.1 | 1.1e-12 | 0.48 | 0.86 | 0.14 | TRUE |
2 | YFS | Blood | SWAP70 | 0.09 | 0.07 | bslmm | 379 | 0.08 | 1.6e-24 | -6.0 | -7.0 | 3.5e-12 | -0.16 | 1.00 | 0.00 | TRUE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SWAP70 | 0.17 | 0.02 | blup | 77 | 0.06 | 1.9e-03 | -5.7 | -5.4 | 7.5e-08 | -0.11 | 0.01 | 0.84 | FALSE |