[Hub]/) : Traits : Diastolic blood pressure, automated reading :

chr17:1,508,522-2,923,933

Best TWAS P=4.95e-11 · Best GWAS P=1.64e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SRR 0.27 0.48 lasso 1 0.48 3.5e-65 -5.6 5.6 2.8e-08 -0.94 0.07 0.93 FALSE
2 GTEx Adipose Subcutaneous SRR 0.16 0.16 lasso 9 0.18 1.9e-14 -6.0 6.6 5.7e-11 -0.94 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum SRR 0.29 0.26 lasso 5 0.25 1.8e-13 -5.6 5.8 6.9e-09 -0.97 0.01 0.99 FALSE
4 GTEx Adrenal Gland SRR 0.38 0.37 lasso 6 0.38 8.1e-15 -5.6 5.8 5.2e-09 -0.94 0.01 0.99 FALSE
5 GTEx Artery Aorta SRR 0.33 0.33 lasso 2 0.32 6.1e-18 -5.6 5.5 4.8e-08 -0.93 0.03 0.97 FALSE
6 GTEx Artery Coronary SRR 0.44 0.28 lasso 8 0.26 2.5e-09 -6.0 6.6 4.9e-11 -0.97 0.01 0.99 TRUE
7 GTEx Artery Tibial SRR 0.22 0.23 lasso 4 0.24 3.9e-19 -6.0 6.0 2.1e-09 -0.99 0.01 0.99 FALSE
8 GTEx Brain Caudate basal ganglia SRR 0.26 0.03 lasso 3 0.02 8.6e-02 -5.8 6.3 2.5e-10 -0.85 0.02 0.87 FALSE
9 GTEx Brain Cerebellar Hemisphere SRR 0.37 0.24 lasso 7 0.22 2.1e-06 -5.6 5.7 1.5e-08 -0.93 0.02 0.98 FALSE
10 GTEx Brain Cerebellum SRR 0.26 0.20 lasso 3 0.21 8.7e-07 -5.6 6.1 1.0e-09 -0.91 0.02 0.96 FALSE
11 GTEx Brain Frontal Cortex BA9 SRR 0.25 0.24 lasso 3 0.21 3.5e-06 -5.6 5.6 2.0e-08 -0.93 0.02 0.95 FALSE
12 GTEx Breast Mammary Tissue SRR 0.20 0.21 lasso 3 0.20 8.2e-11 -5.9 6.0 1.5e-09 -0.98 0.01 0.99 FALSE
13 GTEx Breast Mammary Tissue (Female) SRR 0.24 0.25 lasso 3 0.21 6.3e-07 -5.9 6.0 1.7e-09 -0.98 0.01 0.99 FALSE
14 GTEx Cells EBV-transformed lymphocytes SRR 0.39 0.34 lasso 5 0.35 3.1e-12 -5.6 6.0 1.9e-09 -0.96 0.01 0.99 FALSE
15 GTEx Cells Transformed fibroblasts SRR 0.36 0.38 lasso 4 0.38 8.2e-30 -5.6 5.7 1.1e-08 -0.95 0.03 0.97 FALSE
16 GTEx Colon Sigmoid SRR 0.32 0.35 enet 8 0.32 9.2e-12 -5.6 5.8 4.9e-09 -0.98 0.01 0.99 FALSE
17 GTEx Colon Transverse SRR 0.28 0.21 lasso 5 0.19 1.6e-09 -5.6 5.5 4.1e-08 -0.95 0.01 0.99 FALSE
18 GTEx Esophagus Gastroesophageal Junction SRR 0.40 0.35 lasso 3 0.36 1.1e-13 -5.6 5.6 2.5e-08 -0.94 0.02 0.98 FALSE
19 GTEx Esophagus Mucosa SRR 0.23 0.24 lasso 5 0.24 2.0e-16 -6.0 6.2 5.2e-10 -0.98 0.00 1.00 FALSE
20 GTEx Esophagus Muscularis SRR 0.30 0.39 lasso 3 0.38 3.4e-24 -5.6 5.6 1.9e-08 -0.94 0.03 0.97 FALSE
21 GTEx Heart Atrial Appendage SRR 0.35 0.30 lasso 7 0.29 1.4e-13 -6.0 6.3 2.6e-10 -0.98 0.01 0.99 FALSE
22 GTEx Heart Left Ventricle SRR 0.15 0.16 lasso 3 0.13 2.9e-07 -5.6 5.5 4.1e-08 -0.93 0.02 0.98 FALSE
23 GTEx Liver SRR 0.31 0.00 lasso 7 0.00 3.0e-01 -2.7 6.1 9.7e-10 -0.53 0.04 0.51 FALSE
24 GTEx Lung SRR 0.24 0.28 lasso 2 0.26 3.4e-20 -5.6 5.6 2.4e-08 -0.96 0.04 0.96 FALSE
25 GTEx Muscle Skeletal SRR 0.27 0.27 lasso 6 0.27 7.1e-27 -5.6 5.8 6.9e-09 -0.94 0.06 0.94 FALSE
26 GTEx Nerve Tibial SRR 0.15 0.13 lasso 3 0.13 2.9e-09 -6.0 6.2 7.0e-10 -0.98 0.01 0.99 FALSE
27 GTEx Pancreas SRR 0.13 0.17 lasso 3 0.15 5.2e-07 -6.0 5.9 3.5e-09 -0.99 0.01 0.99 FALSE
28 GTEx Skin Not Sun Exposed Suprapubic SRR 0.18 0.16 enet 18 0.19 7.9e-11 -5.6 5.3 1.2e-07 -0.75 0.01 0.99 FALSE
29 GTEx Skin Sun Exposed Lower leg SRR 0.13 0.15 lasso 4 0.14 2.0e-11 -5.6 5.7 9.6e-09 -0.95 0.03 0.97 FALSE
30 GTEx Spleen SRR 0.21 0.10 lasso 4 0.04 3.1e-02 -5.6 5.7 1.1e-08 -0.95 0.03 0.81 FALSE
31 GTEx Stomach SRR 0.27 0.30 lasso 7 0.28 7.1e-14 -6.0 5.9 3.2e-09 -0.99 0.01 0.99 FALSE
32 GTEx Testis SRR 0.13 0.12 lasso 2 0.09 6.6e-05 -5.6 5.6 1.8e-08 -0.96 0.01 0.98 FALSE
33 GTEx Thyroid SRR 0.26 0.27 lasso 4 0.25 2.0e-19 -5.6 5.6 2.5e-08 -0.95 0.02 0.98 FALSE
34 GTEx Vagina SRR 0.18 0.13 lasso 2 0.11 1.6e-03 -5.2 5.4 5.8e-08 -0.95 0.02 0.80 FALSE
35 GTEx Whole Blood SRR 0.09 0.03 enet 8 0.02 4.5e-03 -5.6 5.8 6.4e-09 -0.91 0.01 0.98 FALSE
36 METSIM Adipose SRR 0.07 0.07 enet 21 0.06 4.4e-09 -5.6 5.7 1.0e-08 -0.90 0.01 0.99 FALSE
37 ROSMAP Brain Pre-frontal Cortex SRR 0.25 0.39 lasso 3 0.39 5.6e-53 -5.6 5.8 8.6e-09 -0.95 0.06 0.94 FALSE
38 YFS Blood SRR 0.17 0.22 lasso 7 0.23 2.5e-72 -5.6 6.0 2.2e-09 -0.97 0.06 0.94 FALSE
39 The Cancer Genome Atlas Bladder Urothelial Carcinoma SRR 0.11 0.09 lasso 4 0.10 6.8e-09 -5.6 5.5 3.3e-08 -0.91 0.01 0.99 FALSE
40 The Cancer Genome Atlas Breast Invasive Carcinoma SRR 0.16 0.16 lasso 5 0.16 2.3e-32 -6.0 6.1 1.3e-09 -0.99 0.00 1.00 FALSE
41 The Cancer Genome Atlas Colon Adenocarcinoma SRR 0.32 0.24 lasso 3 0.23 1.5e-13 -5.6 5.5 2.9e-08 -0.94 0.02 0.98 FALSE
42 The Cancer Genome Atlas Esophageal Carcinoma SRR 0.32 0.13 lasso 2 0.16 9.2e-06 -5.6 5.6 1.9e-08 -0.94 0.02 0.96 FALSE
43 The Cancer Genome Atlas Glioblastoma Multiforme SRR 0.24 0.16 lasso 1 0.13 9.0e-05 -5.6 5.6 2.8e-08 -0.94 0.00 0.96 FALSE
44 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SRR 0.10 0.10 lasso 2 0.09 1.0e-10 -5.6 5.7 9.0e-09 -0.97 0.01 0.99 FALSE
45 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SRR 0.30 0.40 lasso 7 0.39 8.5e-47 -6.0 6.1 1.1e-09 -0.99 0.00 1.00 FALSE
46 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SRR 0.22 0.23 lasso 2 0.21 2.3e-12 -5.6 5.6 1.9e-08 -0.95 0.01 0.99 FALSE
47 The Cancer Genome Atlas Brain Lower Grade Glioma SRR 0.29 0.26 lasso 2 0.27 1.9e-30 -6.0 5.9 2.7e-09 -0.99 0.00 1.00 FALSE
48 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SRR 0.08 0.09 enet 3 0.08 1.7e-04 -5.6 5.8 8.3e-09 -0.97 0.01 0.97 FALSE
49 The Cancer Genome Atlas Lung Adenocarcinoma SRR 0.14 0.18 lasso 2 0.18 4.3e-21 -5.6 5.8 8.7e-09 -0.97 0.01 0.99 FALSE
50 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SRR 0.11 0.12 lasso 2 0.12 4.3e-13 -5.6 5.6 2.5e-08 -0.94 0.02 0.98 FALSE
51 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SRR 0.16 0.20 lasso 3 0.20 2.8e-13 -6.0 6.1 1.3e-09 -1.00 0.00 1.00 FALSE
52 The Cancer Genome Atlas Pancreatic Adenocarcinoma SRR 0.34 0.30 lasso 4 0.30 2.9e-13 -5.6 5.7 9.9e-09 -0.96 0.01 0.99 FALSE
53 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma SRR 0.27 0.19 enet 5 0.21 8.9e-09 -6.0 6.0 2.0e-09 -1.00 0.00 1.00 FALSE
54 The Cancer Genome Atlas Prostate Adenocarcinoma SMG6 0.04 0.01 blup 144 0.02 5.5e-03 -5.2 -6.3 3.7e-10 0.69 0.08 0.31 FALSE
55 The Cancer Genome Atlas Prostate Adenocarcinoma SRR 0.30 0.35 lasso 3 0.36 7.5e-39 -5.6 5.9 4.7e-09 -0.96 0.01 0.99 FALSE
56 The Cancer Genome Atlas Rectum Adenocarcinoma SRR 0.52 0.32 lasso 3 0.40 1.7e-10 -5.6 5.2 2.0e-07 -0.90 0.00 0.99 FALSE
57 The Cancer Genome Atlas Soft Tissue Sarcoma SRR 0.20 0.18 lasso 2 0.20 8.8e-12 -5.6 5.8 5.0e-09 -0.98 0.00 1.00 FALSE
58 The Cancer Genome Atlas Skin Cutaneous Melanoma SRR 0.16 0.03 blup 61 0.02 8.7e-02 -5.6 5.3 1.0e-07 -0.77 0.01 0.65 FALSE
59 The Cancer Genome Atlas Stomach Adenocarcinoma SRR 0.21 0.15 enet 11 0.16 1.1e-11 -6.0 5.3 1.2e-07 -0.93 0.00 1.00 FALSE
60 The Cancer Genome Atlas Testicular Germ Cell Tumors SGSM2 0.13 0.01 blup 81 0.01 1.1e-01 3.7 -5.8 8.3e-09 0.67 0.02 0.40 FALSE
61 The Cancer Genome Atlas Thyroid Carcinoma SRR 0.56 0.50 lasso 4 0.50 5.2e-55 -5.6 5.7 1.1e-08 -0.94 0.04 0.96 FALSE