[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr7:119,892,061-121,729,795

Best TWAS P=1.78e-238 · Best GWAS P=0 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	CPED1	0.08	0.00	lasso	4	0.00	1.4e-01	35.8	33.0	1.8e-238	0.86	0.03	0.91	TRUE
2	GTEx	Adipose Subcutaneous	CPED1	0.10	0.02	enet	26	0.04	6.2e-04	17.1	22.2	6.9e-109	0.35	0.42	0.23	TRUE
8	GTEx	Skin Sun Exposed Lower leg	FAM3C	0.16	0.07	enet	27	0.10	1.6e-08	-12.5	22.0	1.6e-107	0.47	0.66	0.32	TRUE
11	NTR	Blood	C7orf58	0.04	0.02	lasso	7	0.03	9.5e-10	21.2	15.3	6.4e-53	0.19	1.00	0.00	TRUE
5	GTEx	Nerve Tibial	CPED1	0.09	0.03	lasso	3	0.06	6.4e-05	20.1	14.8	1.7e-49	0.16	0.10	0.04	TRUE
6	GTEx	Skin Not Sun Exposed Suprapubic	FAM3C	0.15	0.09	lasso	7	0.10	6.2e-06	-11.9	13.3	1.4e-40	0.27	0.75	0.09	TRUE
7	GTEx	Skin Sun Exposed Lower leg	CPED1	0.05	0.01	lasso	4	0.02	1.3e-02	2.0	5.3	1.2e-07	0.04	0.27	0.04	TRUE
13	ROSMAP	Brain Pre-frontal Cortex	FAM3C	0.07	0.02	blup	369	0.04	1.6e-05	22.1	-5.2	2.6e-07	-0.24	0.52	0.06	TRUE
14	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C7orf58	0.08	0.01	blup	158	0.01	5.1e-02	22.0	21.6	1.1e-103	0.45	0.05	0.23	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	CPED1	0.05	0.01	blup	447	0.03	6.1e-05	1.1	-21.3	6.8e-101	-0.39	0.37	0.27	FALSE
4	GTEx	Cells Transformed fibroblasts	CPED1	0.20	0.12	lasso	5	0.16	7.6e-12	20.9	20.3	2.7e-91	0.27	1.00	0.00	FALSE
9	METSIM	Adipose	FAM3C	0.12	0.13	bslmm	376	0.13	7.0e-19	-14.7	16.7	1.7e-62	0.39	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	WNT16	0.09	0.04	enet	32	0.04	8.1e-06	-12.9	-10.3	1.2e-24	-0.19	0.81	0.06	FALSE
10	METSIM	Adipose	ING3	0.02	0.00	blup	352	0.00	6.0e-02	1.4	7.4	1.6e-13	0.05	0.06	0.03	FALSE