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Traits
:
Heel bone mineral density (BMD) T-score, automated (left)
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chr11:114,340,771-116,072,203
Best TWAS P=1.44e-12 · Best GWAS P=1.41e-16 conditioned to 0.624
114.4M
114.6M
114.8M
115M
115.2M
115.4M
115.6M
115.8M
116M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
CADM1
0.11
0.11
bslmm
631
0.12
1.1e-35
8.3
-7.1
1.4e-12
-0.94
0.00
1.00
TRUE
2
METSIM
Adipose
CADM1
0.08
0.00
enet
38
0.02
8.3e-04
5.7
5.3
1.4e-07
0.31
0.13
0.26
TRUE
1
GTEx
Thyroid
CADM1
0.55
0.53
lasso
3
0.53
2.9e-47
6.5
-6.5
9.4e-11
-0.82
1.00
0.00
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
CADM1
0.10
0.05
blup
191
0.09
2.7e-09
-6.7
-5.2
1.8e-07
-0.71
0.17
0.83
FALSE