Best TWAS P=1.44e-12 · Best GWAS P=1.41e-16 conditioned to 0.624
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | CADM1 | 0.55 | 0.53 | lasso | 3 | 0.53 | 2.9e-47 | 6.5 | -6.5 | 9.4e-11 | -0.82 | 1.00 | 0.00 | FALSE |
| 2 | METSIM | Adipose | CADM1 | 0.08 | 0.00 | enet | 38 | 0.02 | 8.3e-04 | 5.7 | 5.3 | 1.4e-07 | 0.31 | 0.13 | 0.26 | TRUE |
| 3 | YFS | Blood | CADM1 | 0.11 | 0.11 | bslmm | 631 | 0.12 | 1.1e-35 | 8.3 | -7.1 | 1.4e-12 | -0.94 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | CADM1 | 0.10 | 0.05 | blup | 191 | 0.09 | 2.7e-09 | -6.7 | -5.2 | 1.8e-07 | -0.71 | 0.17 | 0.83 | FALSE |